1RZ9A

Crystal structure of aav rep complexed with the rep-binding sequence
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
193
structure length
193
Chain Sequence
MATFYEVIVRVPFDVEEHLPGISDSFVDWVTGQIWELPPESDLNLTLVEQPQLTVADRIRRVFLYEWNKFSKQESKFFVQFEKGSEYFHLHTLVETSGISSMVLGRYVSQIRAQLVKVVFQGIEPQINDWVAITKVKKGGANKVVDSGYIPAYLLPKVQPELQWAWTNLDEYKLAALNLEERKRLVAQFLAES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
pubmed doi rcsb
molecule tags Viral protein/dna
source organism Adeno-associated virus - 5
molecule keywords 26-MER
total genus 59
structure length 193
sequence length 193
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2003-12-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08724 Rep_N Rep protein catalytic domain like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 1rz9A00
4GDFA 1UUTA 1Z1DB 2FUFA 3QN2A 4NBPA 1L5IA 2IF9A 4ZO0A 4FB3A 1L2MA 2TBDA 3QFQA 2IPRA 3QK2A 2ITLA 1RZ9A 2NL8A 4ZQ9A 2HW0A 1TBDA 1M55A 5CYNA 4LMDA 2ITJA 5D9IA 2NTCA 5BYGA 5DCXA 4FGNA 4LIFA
chains in the Genus database with same CATH superfamily
4GDFA 1KSXA 1UUTA 1Z1DB 2FUFA 4KW3A 3QN2A 4NBPA 1L5IA 2IF9A 4ZO0A 4FB3A 3DKXA 1L2MA 2TBDA 3QFQA 2IPRA 3QK2A 2ITLA 4U87A 1R9WA 1RZ9A 2NL8A 4ZQ9A 2HW0A 3DKYA 1TBDA 1M55A 5CYNA 1KSYA 4LMDA 2ITJA 5D9IA 2NTCA 5BYGA 5DCXA 1F08A 4FGNA 4LIFA
chains in the Genus database with same CATH topology
4GDFA 1KSXA 1UUTA 1Z1DB 2FUFA 4KW3A 3QN2A 4NBPA 1L5IA 2IF9A 4ZO0A 4FB3A 3DKXA 1L2MA 2TBDA 3QFQA 2IPRA 3QK2A 2ITLA 4U87A 1R9WA 1RZ9A 2NL8A 4ZQ9A 2HW0A 3DKYA 1TBDA 1M55A 5CYNA 1KSYA 4LMDA 2ITJA 5D9IA 2NTCA 5BYGA 5DCXA 1F08A 4FGNA 4LIFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GDF A;  1UUT A;  1Z1D B;  2FUF A;  3QN2 A;  4NBP A;  1L5I A;  2IF9 A;  4ZO0 A;  4FB3 A;  1L2M A;  2TBD A;  3QFQ A;  2IPR A;  3QK2 A;  2ITL A;  1RZ9 A;  2NL8 A;  4ZQ9 A;  2HW0 A;  1TBD A;  1M55 A;  5CYN A;  4LMD A;  2ITJ A;  5D9I A;  2NTC A;  5BYG A;  5DCX A;  4FGN A;  4LIF A; 
#chains in the Genus database with same CATH topology
 4GDF A;  1KSX A;  1UUT A;  1Z1D B;  2FUF A;  4KW3 A;  3QN2 A;  4NBP A;  1L5I A;  2IF9 A;  4ZO0 A;  4FB3 A;  3DKX A;  1L2M A;  2TBD A;  3QFQ A;  2IPR A;  3QK2 A;  2ITL A;  4U87 A;  1R9W A;  1RZ9 A;  2NL8 A;  4ZQ9 A;  2HW0 A;  3DKY A;  1TBD A;  1M55 A;  5CYN A;  1KSY A;  4LMD A;  2ITJ A;  5D9I A;  2NTC A;  5BYG A;  5DCX A;  1F08 A;  4FGN A;  4LIF A; 
#chains in the Genus database with same CATH homology
 4GDF A;  1KSX A;  1UUT A;  1Z1D B;  2FUF A;  4KW3 A;  3QN2 A;  4NBP A;  1L5I A;  2IF9 A;  4ZO0 A;  4FB3 A;  3DKX A;  1L2M A;  2TBD A;  3QFQ A;  2IPR A;  3QK2 A;  2ITL A;  4U87 A;  1R9W A;  1RZ9 A;  2NL8 A;  4ZQ9 A;  2HW0 A;  3DKY A;  1TBD A;  1M55 A;  5CYN A;  1KSY A;  4LMD A;  2ITJ A;  5D9I A;  2NTC A;  5BYG A;  5DCX A;  1F08 A;  4FGN A;  4LIF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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