1RZ9A

Crystal structure of aav rep complexed with the rep-binding sequence
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
193
structure length
193
Chain Sequence
MATFYEVIVRVPFDVEEHLPGISDSFVDWVTGQIWELPPESDLNLTLVEQPQLTVADRIRRVFLYEWNKFSKQESKFFVQFEKGSEYFHLHTLVETSGISSMVLGRYVSQIRAQLVKVVFQGIEPQINDWVAITKVKKGGANKVVDSGYIPAYLLPKVQPELQWAWTNLDEYKLAALNLEERKRLVAQFLAES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
pubmed doi rcsb
molecule keywords 26-MER
molecule tags Viral protein/dna
source organism Adeno-associated virus - 5
total genus 59
structure length 193
sequence length 193
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2003-12-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08724 Rep_N Rep protein catalytic domain like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 1rz9A00
1Z1DB 2FUFA 5DCXA 4ZQ9A 2IF9A 1RZ9A 2NL8A 5BYGA 3QFQA 3QK2A 1M55A 2IPRA 2ITJA 5CYNA 4LIFA 4NBPA 4FGNA 2ITLA 4LMDA 2HW0A 3QN2A 4ZO0A 5D9IA 2NTCA 1TBDA 1UUTA 1L2MA 4FB3A 1L5IA 2TBDA 4GDFA
chains in the Genus database with same CATH superfamily
1Z1DB 2FUFA 5DCXA 4ZQ9A 4KW3A 2IF9A 1RZ9A 2NL8A 1KSYA 5BYGA 3QFQA 3QK2A 1M55A 2IPRA 2ITJA 4U87A 4LIFA 5CYNA 4NBPA 4FGNA 2ITLA 4LMDA 2HW0A 3DKXA 3QN2A 4ZO0A 1R9WA 1F08A 5D9IA 2NTCA 1TBDA 1UUTA 3DKYA 1L2MA 1KSXA 4FB3A 1L5IA 2TBDA 4GDFA
chains in the Genus database with same CATH topology
1Z1DB 2FUFA 5DCXA 4ZQ9A 4KW3A 2IF9A 1RZ9A 2NL8A 1KSYA 5BYGA 3QFQA 3QK2A 1M55A 2IPRA 2ITJA 4U87A 4LIFA 5CYNA 4NBPA 4FGNA 2ITLA 4LMDA 2HW0A 3DKXA 3QN2A 4ZO0A 1R9WA 1F08A 5D9IA 2NTCA 1TBDA 1UUTA 3DKYA 1L2MA 1KSXA 4FB3A 1L5IA 2TBDA 4GDFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z1D B;  2FUF A;  5DCX A;  4ZQ9 A;  2IF9 A;  1RZ9 A;  2NL8 A;  5BYG A;  3QFQ A;  3QK2 A;  1M55 A;  2IPR A;  2ITJ A;  5CYN A;  4LIF A;  4NBP A;  4FGN A;  2ITL A;  4LMD A;  2HW0 A;  3QN2 A;  4ZO0 A;  5D9I A;  2NTC A;  1TBD A;  1UUT A;  1L2M A;  4FB3 A;  1L5I A;  2TBD A;  4GDF A; 
#chains in the Genus database with same CATH topology
 1Z1D B;  2FUF A;  5DCX A;  4ZQ9 A;  4KW3 A;  2IF9 A;  1RZ9 A;  2NL8 A;  1KSY A;  5BYG A;  3QFQ A;  3QK2 A;  1M55 A;  2IPR A;  2ITJ A;  4U87 A;  4LIF A;  5CYN A;  4NBP A;  4FGN A;  2ITL A;  4LMD A;  2HW0 A;  3DKX A;  3QN2 A;  4ZO0 A;  1R9W A;  1F08 A;  5D9I A;  2NTC A;  1TBD A;  1UUT A;  3DKY A;  1L2M A;  1KSX A;  4FB3 A;  1L5I A;  2TBD A;  4GDF A; 
#chains in the Genus database with same CATH homology
 1Z1D B;  2FUF A;  5DCX A;  4ZQ9 A;  4KW3 A;  2IF9 A;  1RZ9 A;  2NL8 A;  1KSY A;  5BYG A;  3QFQ A;  3QK2 A;  1M55 A;  2IPR A;  2ITJ A;  4U87 A;  4LIF A;  5CYN A;  4NBP A;  4FGN A;  2ITL A;  4LMD A;  2HW0 A;  3DKX A;  3QN2 A;  4ZO0 A;  1R9W A;  1F08 A;  5D9I A;  2NTC A;  1TBD A;  1UUT A;  3DKY A;  1L2M A;  1KSX A;  4FB3 A;  1L5I A;  2TBD A;  4GDF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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