1RZ9A

Crystal structure of aav rep complexed with the rep-binding sequence
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
193
structure length
193
Chain Sequence
MATFYEVIVRVPFDVEEHLPGISDSFVDWVTGQIWELPPESDLNLTLVEQPQLTVADRIRRVFLYEWNKFSKQESKFFVQFEKGSEYFHLHTLVETSGISSMVLGRYVSQIRAQLVKVVFQGIEPQINDWVAITKVKKGGANKVVDSGYIPAYLLPKVQPELQWAWTNLDEYKLAALNLEERKRLVAQFLAES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
pubmed doi rcsb
molecule keywords 26-MER
molecule tags Viral protein/dna
source organism Adeno-associated virus - 5
total genus 59
structure length 193
sequence length 193
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2003-12-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08724 Rep_N Rep protein catalytic domain like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 1rz9A00
5BYGA 2NTCA 1RZ9A 3QFQA 2HW0A 2ITLA 1L2MA 1Z1DB 1M55A 4LMDA 4GDFA 2FUFA 1L5IA 2IPRA 3QN2A 4ZQ9A 1UUTA 4LIFA 5D9IA 4FGNA 2IF9A 5DCXA 3QK2A 4FB3A 5CYNA 4ZO0A 2NL8A 1TBDA 4NBPA 2TBDA 2ITJA
chains in the Genus database with same CATH superfamily
5BYGA 2NTCA 3DKXA 4U87A 1RZ9A 3QFQA 2HW0A 2ITLA 1L2MA 1KSXA 1Z1DB 1M55A 1F08A 4LMDA 4GDFA 2FUFA 4KW3A 1KSYA 1L5IA 2IPRA 3QN2A 3DKYA 4ZQ9A 1UUTA 4LIFA 5D9IA 4FGNA 2IF9A 5DCXA 1R9WA 3QK2A 4FB3A 5CYNA 4ZO0A 2NL8A 1TBDA 4NBPA 2TBDA 2ITJA
chains in the Genus database with same CATH topology
5BYGA 2NTCA 3DKXA 4U87A 1RZ9A 3QFQA 2HW0A 2ITLA 1L2MA 1KSXA 1Z1DB 1M55A 1F08A 4LMDA 4GDFA 2FUFA 4KW3A 1KSYA 1L5IA 2IPRA 3QN2A 3DKYA 4ZQ9A 1UUTA 4LIFA 5D9IA 4FGNA 2IF9A 5DCXA 1R9WA 3QK2A 4FB3A 5CYNA 4ZO0A 2NL8A 1TBDA 4NBPA 2TBDA 2ITJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BYG A;  2NTC A;  1RZ9 A;  3QFQ A;  2HW0 A;  2ITL A;  1L2M A;  1Z1D B;  1M55 A;  4LMD A;  4GDF A;  2FUF A;  1L5I A;  2IPR A;  3QN2 A;  4ZQ9 A;  1UUT A;  4LIF A;  5D9I A;  4FGN A;  2IF9 A;  5DCX A;  3QK2 A;  4FB3 A;  5CYN A;  4ZO0 A;  2NL8 A;  1TBD A;  4NBP A;  2TBD A;  2ITJ A; 
#chains in the Genus database with same CATH topology
 5BYG A;  2NTC A;  3DKX A;  4U87 A;  1RZ9 A;  3QFQ A;  2HW0 A;  2ITL A;  1L2M A;  1KSX A;  1Z1D B;  1M55 A;  1F08 A;  4LMD A;  4GDF A;  2FUF A;  4KW3 A;  1KSY A;  1L5I A;  2IPR A;  3QN2 A;  3DKY A;  4ZQ9 A;  1UUT A;  4LIF A;  5D9I A;  4FGN A;  2IF9 A;  5DCX A;  1R9W A;  3QK2 A;  4FB3 A;  5CYN A;  4ZO0 A;  2NL8 A;  1TBD A;  4NBP A;  2TBD A;  2ITJ A; 
#chains in the Genus database with same CATH homology
 5BYG A;  2NTC A;  3DKX A;  4U87 A;  1RZ9 A;  3QFQ A;  2HW0 A;  2ITL A;  1L2M A;  1KSX A;  1Z1D B;  1M55 A;  1F08 A;  4LMD A;  4GDF A;  2FUF A;  4KW3 A;  1KSY A;  1L5I A;  2IPR A;  3QN2 A;  3DKY A;  4ZQ9 A;  1UUT A;  4LIF A;  5D9I A;  4FGN A;  2IF9 A;  5DCX A;  1R9W A;  3QK2 A;  4FB3 A;  5CYN A;  4ZO0 A;  2NL8 A;  1TBD A;  4NBP A;  2TBD A;  2ITJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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