1RZ9A

Crystal structure of aav rep complexed with the rep-binding sequence
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
193
structure length
193
Chain Sequence
MATFYEVIVRVPFDVEEHLPGISDSFVDWVTGQIWELPPESDLNLTLVEQPQLTVADRIRRVFLYEWNKFSKQESKFFVQFEKGSEYFHLHTLVETSGISSMVLGRYVSQIRAQLVKVVFQGIEPQINDWVAITKVKKGGANKVVDSGYIPAYLLPKVQPELQWAWTNLDEYKLAALNLEERKRLVAQFLAES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
pubmed doi rcsb
molecule tags Viral protein/dna
source organism Adeno-associated virus - 5
molecule keywords 26-MER
total genus 59
structure length 193
sequence length 193
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2003-12-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08724 Rep_N Rep protein catalytic domain like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 1rz9A00
1RZ9A 1L2MA 2FUFA 2NL8A 2IF9A 3QFQA 3QK2A 2ITJA 5D9IA 4FB3A 4GDFA 1UUTA 4ZO0A 1TBDA 2ITLA 1Z1DB 2TBDA 4LMDA 5BYGA 5CYNA 2NTCA 4NBPA 2HW0A 2IPRA 1L5IA 5DCXA 4FGNA 4ZQ9A 4LIFA 1M55A 3QN2A
chains in the Genus database with same CATH superfamily
4U87A 4KW3A 1RZ9A 1L2MA 1R9WA 2FUFA 2NL8A 2IF9A 3QFQA 3DKYA 3QK2A 2ITJA 5D9IA 4FB3A 1F08A 4GDFA 1UUTA 4ZO0A 1TBDA 2ITLA 1Z1DB 2TBDA 4LMDA 5BYGA 1KSXA 5CYNA 2NTCA 2HW0A 2IPRA 4NBPA 3DKXA 1L5IA 5DCXA 4FGNA 4ZQ9A 1KSYA 4LIFA 1M55A 3QN2A
chains in the Genus database with same CATH topology
4U87A 4KW3A 1RZ9A 1L2MA 1R9WA 2FUFA 2NL8A 2IF9A 3QFQA 3DKYA 3QK2A 2ITJA 5D9IA 4FB3A 1F08A 4GDFA 1UUTA 4ZO0A 1TBDA 2ITLA 1Z1DB 2TBDA 4LMDA 5BYGA 1KSXA 5CYNA 2NTCA 2HW0A 2IPRA 4NBPA 3DKXA 1L5IA 5DCXA 4FGNA 4ZQ9A 1KSYA 4LIFA 1M55A 3QN2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RZ9 A;  1L2M A;  2FUF A;  2NL8 A;  2IF9 A;  3QFQ A;  3QK2 A;  2ITJ A;  5D9I A;  4FB3 A;  4GDF A;  1UUT A;  4ZO0 A;  1TBD A;  2ITL A;  1Z1D B;  2TBD A;  4LMD A;  5BYG A;  5CYN A;  2NTC A;  4NBP A;  2HW0 A;  2IPR A;  1L5I A;  5DCX A;  4FGN A;  4ZQ9 A;  4LIF A;  1M55 A;  3QN2 A; 
#chains in the Genus database with same CATH topology
 4U87 A;  4KW3 A;  1RZ9 A;  1L2M A;  1R9W A;  2FUF A;  2NL8 A;  2IF9 A;  3QFQ A;  3DKY A;  3QK2 A;  2ITJ A;  5D9I A;  4FB3 A;  1F08 A;  4GDF A;  1UUT A;  4ZO0 A;  1TBD A;  2ITL A;  1Z1D B;  2TBD A;  4LMD A;  5BYG A;  1KSX A;  5CYN A;  2NTC A;  2HW0 A;  2IPR A;  4NBP A;  3DKX A;  1L5I A;  5DCX A;  4FGN A;  4ZQ9 A;  1KSY A;  4LIF A;  1M55 A;  3QN2 A; 
#chains in the Genus database with same CATH homology
 4U87 A;  4KW3 A;  1RZ9 A;  1L2M A;  1R9W A;  2FUF A;  2NL8 A;  2IF9 A;  3QFQ A;  3DKY A;  3QK2 A;  2ITJ A;  5D9I A;  4FB3 A;  1F08 A;  4GDF A;  1UUT A;  4ZO0 A;  1TBD A;  2ITL A;  1Z1D B;  2TBD A;  4LMD A;  5BYG A;  1KSX A;  5CYN A;  2NTC A;  2HW0 A;  2IPR A;  4NBP A;  3DKX A;  1L5I A;  5DCX A;  4FGN A;  4ZQ9 A;  1KSY A;  4LIF A;  1M55 A;  3QN2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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