2ITLA

The origin binding domain of the sv40 large t antigen bound to the functional pen palindrome dna (23 bp)
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
120
structure length
120
Chain Sequence
DPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Dna binding protein/dna
molecule keywords 24-nt PEN element of the SV40 DNA origin
publication title Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
pubmed doi rcsb
source organism Simian virus 40
total genus 33
structure length 120
sequence length 120
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 2itlA00
3QN2A 2ITLA 4NBPA 4FB3A 5BYGA 4LIFA 2NTCA 1L2MA 5DCXA 1TBDA 2HW0A 4ZQ9A 4ZO0A 1L5IA 3QFQA 5CYNA 2IPRA 4LMDA 2NL8A 1Z1DB 2IF9A 3QK2A 1M55A 2ITJA 2TBDA 1RZ9A 4GDFA 1UUTA 4FGNA 2FUFA 5D9IA
chains in the Genus database with same CATH superfamily
3QN2A 1R9WA 4U87A 2ITLA 4NBPA 1KSXA 4FB3A 5BYGA 4LIFA 2NTCA 1TBDA 1L2MA 5DCXA 2HW0A 4ZQ9A 4ZO0A 1L5IA 3QFQA 5CYNA 2IPRA 4LMDA 2NL8A 1Z1DB 3DKYA 3DKXA 2IF9A 3QK2A 1M55A 2ITJA 2TBDA 1RZ9A 4GDFA 1UUTA 1KSYA 4FGNA 2FUFA 1F08A 5D9IA 4KW3A
chains in the Genus database with same CATH topology
3QN2A 1R9WA 4U87A 2ITLA 4NBPA 1KSXA 4FB3A 5BYGA 4LIFA 2NTCA 1TBDA 1L2MA 5DCXA 2HW0A 4ZQ9A 4ZO0A 1L5IA 3QFQA 5CYNA 2IPRA 4LMDA 2NL8A 1Z1DB 3DKYA 3DKXA 2IF9A 3QK2A 1M55A 2ITJA 2TBDA 1RZ9A 4GDFA 1UUTA 1KSYA 4FGNA 2FUFA 1F08A 5D9IA 4KW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QN2 A;  2ITL A;  4NBP A;  4FB3 A;  5BYG A;  4LIF A;  2NTC A;  1L2M A;  5DCX A;  1TBD A;  2HW0 A;  4ZQ9 A;  4ZO0 A;  1L5I A;  3QFQ A;  5CYN A;  2IPR A;  4LMD A;  2NL8 A;  1Z1D B;  2IF9 A;  3QK2 A;  1M55 A;  2ITJ A;  2TBD A;  1RZ9 A;  4GDF A;  1UUT A;  4FGN A;  2FUF A;  5D9I A; 
#chains in the Genus database with same CATH topology
 3QN2 A;  1R9W A;  4U87 A;  2ITL A;  4NBP A;  1KSX A;  4FB3 A;  5BYG A;  4LIF A;  2NTC A;  1TBD A;  1L2M A;  5DCX A;  2HW0 A;  4ZQ9 A;  4ZO0 A;  1L5I A;  3QFQ A;  5CYN A;  2IPR A;  4LMD A;  2NL8 A;  1Z1D B;  3DKY A;  3DKX A;  2IF9 A;  3QK2 A;  1M55 A;  2ITJ A;  2TBD A;  1RZ9 A;  4GDF A;  1UUT A;  1KSY A;  4FGN A;  2FUF A;  1F08 A;  5D9I A;  4KW3 A; 
#chains in the Genus database with same CATH homology
 3QN2 A;  1R9W A;  4U87 A;  2ITL A;  4NBP A;  1KSX A;  4FB3 A;  5BYG A;  4LIF A;  2NTC A;  1TBD A;  1L2M A;  5DCX A;  2HW0 A;  4ZQ9 A;  4ZO0 A;  1L5I A;  3QFQ A;  5CYN A;  2IPR A;  4LMD A;  2NL8 A;  1Z1D B;  3DKY A;  3DKX A;  2IF9 A;  3QK2 A;  1M55 A;  2ITJ A;  2TBD A;  1RZ9 A;  4GDF A;  1UUT A;  1KSY A;  4FGN A;  2FUF A;  1F08 A;  5D9I A;  4KW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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