4LMDA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
128
structure length
128
Chain Sequence
EDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Large T antigen
publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
source organism Jc polyomavirus
total genus 38
structure length 128
sequence length 128
chains with identical sequence B
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4lmdA00
4ZO0A 1UUTA 1TBDA 2ITLA 2IF9A 4GDFA 3QFQA 4LIFA 2TBDA 3QN2A 1L5IA 1Z1DB 2NL8A 2HW0A 5D9IA 4FB3A 4FGNA 4LMDA 2IPRA 3QK2A 2ITJA 2FUFA 5DCXA 5BYGA 2NTCA 4ZQ9A 1L2MA 4NBPA 1M55A 5CYNA 1RZ9A
chains in the Genus database with same CATH superfamily
4ZO0A 1R9WA 1TBDA 4U87A 1UUTA 2ITLA 2IF9A 4GDFA 3QFQA 4LIFA 2TBDA 3QN2A 1L5IA 1Z1DB 2NL8A 2HW0A 5D9IA 4FB3A 1KSXA 1F08A 4KW3A 4FGNA 4LMDA 2IPRA 1KSYA 3QK2A 3DKXA 2ITJA 3DKYA 2FUFA 5DCXA 5BYGA 2NTCA 4ZQ9A 1L2MA 4NBPA 1M55A 5CYNA 1RZ9A
chains in the Genus database with same CATH topology
4ZO0A 1R9WA 1TBDA 4U87A 1UUTA 2ITLA 2IF9A 4GDFA 3QFQA 4LIFA 2TBDA 3QN2A 1L5IA 1Z1DB 2NL8A 2HW0A 5D9IA 4FB3A 1KSXA 1F08A 4KW3A 4FGNA 4LMDA 2IPRA 1KSYA 3QK2A 3DKXA 2ITJA 3DKYA 2FUFA 5DCXA 5BYGA 2NTCA 4ZQ9A 1L2MA 4NBPA 1M55A 5CYNA 1RZ9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZO0 A;  1UUT A;  1TBD A;  2ITL A;  2IF9 A;  4GDF A;  3QFQ A;  4LIF A;  2TBD A;  3QN2 A;  1L5I A;  1Z1D B;  2NL8 A;  2HW0 A;  5D9I A;  4FB3 A;  4FGN A;  4LMD A;  2IPR A;  3QK2 A;  2ITJ A;  2FUF A;  5DCX A;  5BYG A;  2NTC A;  4ZQ9 A;  1L2M A;  4NBP A;  1M55 A;  5CYN A;  1RZ9 A; 
#chains in the Genus database with same CATH topology
 4ZO0 A;  1R9W A;  1TBD A;  4U87 A;  1UUT A;  2ITL A;  2IF9 A;  4GDF A;  3QFQ A;  4LIF A;  2TBD A;  3QN2 A;  1L5I A;  1Z1D B;  2NL8 A;  2HW0 A;  5D9I A;  4FB3 A;  1KSX A;  1F08 A;  4KW3 A;  4FGN A;  4LMD A;  2IPR A;  1KSY A;  3QK2 A;  3DKX A;  2ITJ A;  3DKY A;  2FUF A;  5DCX A;  5BYG A;  2NTC A;  4ZQ9 A;  1L2M A;  4NBP A;  1M55 A;  5CYN A;  1RZ9 A; 
#chains in the Genus database with same CATH homology
 4ZO0 A;  1R9W A;  1TBD A;  4U87 A;  1UUT A;  2ITL A;  2IF9 A;  4GDF A;  3QFQ A;  4LIF A;  2TBD A;  3QN2 A;  1L5I A;  1Z1D B;  2NL8 A;  2HW0 A;  5D9I A;  4FB3 A;  1KSX A;  1F08 A;  4KW3 A;  4FGN A;  4LMD A;  2IPR A;  1KSY A;  3QK2 A;  3DKX A;  2ITJ A;  3DKY A;  2FUF A;  5DCX A;  5BYG A;  2NTC A;  4ZQ9 A;  1L2M A;  4NBP A;  1M55 A;  5CYN A;  1RZ9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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