4LIFA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
127
structure length
127
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase, dna binding protein
molecule keywords Large T antigen
publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
source organism Jc polyomavirus
total genus 28
structure length 127
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4lifA00
5BYGA 2IF9A 1RZ9A 2ITLA 4NBPA 2ITJA 4ZQ9A 1UUTA 4GDFA 4FGNA 2HW0A 2NL8A 1Z1DB 5DCXA 5D9IA 1TBDA 3QN2A 4LMDA 4FB3A 2TBDA 3QK2A 2FUFA 4LIFA 5CYNA 1L5IA 1M55A 3QFQA 1L2MA 2NTCA 2IPRA 4ZO0A
chains in the Genus database with same CATH superfamily
3DKXA 5BYGA 2IF9A 1RZ9A 1KSXA 1R9WA 2ITLA 1F08A 3DKYA 2ITJA 4ZQ9A 1UUTA 4KW3A 4GDFA 4FGNA 1KSYA 2HW0A 2NL8A 1Z1DB 5DCXA 5D9IA 1TBDA 3QN2A 4LMDA 4FB3A 2TBDA 3QK2A 4U87A 2FUFA 4LIFA 5CYNA 1L5IA 1M55A 3QFQA 1L2MA 2NTCA 2IPRA 4ZO0A 4NBPA
chains in the Genus database with same CATH topology
3DKXA 5BYGA 2IF9A 1RZ9A 1KSXA 1R9WA 2ITLA 1F08A 3DKYA 2ITJA 4ZQ9A 1UUTA 4KW3A 4GDFA 4FGNA 1KSYA 2HW0A 2NL8A 1Z1DB 5DCXA 5D9IA 1TBDA 3QN2A 4LMDA 4FB3A 2TBDA 3QK2A 4U87A 2FUFA 4LIFA 5CYNA 1L5IA 1M55A 3QFQA 1L2MA 2NTCA 2IPRA 4ZO0A 4NBPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BYG A;  2IF9 A;  1RZ9 A;  2ITL A;  4NBP A;  2ITJ A;  4ZQ9 A;  1UUT A;  4GDF A;  4FGN A;  2HW0 A;  2NL8 A;  1Z1D B;  5DCX A;  5D9I A;  1TBD A;  3QN2 A;  4LMD A;  4FB3 A;  2TBD A;  3QK2 A;  2FUF A;  4LIF A;  5CYN A;  1L5I A;  1M55 A;  3QFQ A;  1L2M A;  2NTC A;  2IPR A;  4ZO0 A; 
#chains in the Genus database with same CATH topology
 3DKX A;  5BYG A;  2IF9 A;  1RZ9 A;  1KSX A;  1R9W A;  2ITL A;  1F08 A;  3DKY A;  2ITJ A;  4ZQ9 A;  1UUT A;  4KW3 A;  4GDF A;  4FGN A;  1KSY A;  2HW0 A;  2NL8 A;  1Z1D B;  5DCX A;  5D9I A;  1TBD A;  3QN2 A;  4LMD A;  4FB3 A;  2TBD A;  3QK2 A;  4U87 A;  2FUF A;  4LIF A;  5CYN A;  1L5I A;  1M55 A;  3QFQ A;  1L2M A;  2NTC A;  2IPR A;  4ZO0 A;  4NBP A; 
#chains in the Genus database with same CATH homology
 3DKX A;  5BYG A;  2IF9 A;  1RZ9 A;  1KSX A;  1R9W A;  2ITL A;  1F08 A;  3DKY A;  2ITJ A;  4ZQ9 A;  1UUT A;  4KW3 A;  4GDF A;  4FGN A;  1KSY A;  2HW0 A;  2NL8 A;  1Z1D B;  5DCX A;  5D9I A;  1TBD A;  3QN2 A;  4LMD A;  4FB3 A;  2TBD A;  3QK2 A;  4U87 A;  2FUF A;  4LIF A;  5CYN A;  1L5I A;  1M55 A;  3QFQ A;  1L2M A;  2NTC A;  2IPR A;  4ZO0 A;  4NBP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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