1SMYE

Structural basis for transcription regulation by alarmone ppgpp
Total Genus 18
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
95
structure length
95
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLEPEERPKMQTLEGLFDDPNAETWAMKELLTGRLVFGENLVPEDRLQKEMERIYPGE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis for transcription regulation by alarmone ppGpp
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-directed RNA polymerase alpha chain
total genus 18
structure length 95
sequence length 95
chains with identical sequence O
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2004-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1smyE00
3DXJE 3S14F 3GTJF 4YFNE 3S1MF 1TWCF 2JA7F 4BY1F 1I50F 4BBSF 4C3JF 3K7AF 1IW7E 5C44F 1K83F 4YG2E 3HOYF 3HOUF 5IYCF 5C4XF 2BE5E 2B63F 2R92F 2O5JE 3HOWF 4A3LF 2E2HF 1TWHF 3S1RF 3PO2F 4MQ9E 5IP9F 2NVYF 5FJ8F 4A3KF 4A3MF 4A3EF 2PMZK 4G7OE 3GTKF 3GTQF 5D4EE 4LJZE 2CW0E 3GTPF 3M4OF 2E2IF 4A93F 3M3YF 3PO3F 3GTMF 2YU9F 2R93F 1TWGF 5M3FF 4Y52F 3S17F 4KMUE 4LLGE 3S1NF 4BXXF 4BBRF 2WAQK 2A68E 4XLNE 5TMCE 5E17E 1YNNK 3GTOF 3H0GF 4A3JF 2R7ZF 3EQLE 2JA6F 1YNJK 5BYHE 4A3IF 4YFXE 2NVXF 1ZYRE 5M5YF 5C3EF 4XSZE 2WB1I 3S2DF 1TWAF 4OIRE 5D4DE 1I6VE 2NVQF 1I3QF 3I4MF 3HOZF 1SMYE 3I4NF 4C3IF 4XLPE 3CQZF 1HQME 4LK0E 5M3MF 5D4CE 2O5IE 2VUMF 3S16F 5IPLE 4JK1E 4KN7E 4KN4E 4OIPE 5IYBF 1Y1WF 4LK1E 4XSXE 1QKLA 2PPBE 2A69E 1Y1VF 4G7HE 3HOVF 4A3BF 4Q5SE 4YFKE 4MEXE 3H3VG 2A6EE 4A3DF 4A3GF 4C3HF 2JA8F 4AYBK 3RZOF 3RZDF 3HKZK 4MEYE 1TWFF 1SFOF 5M5WF 3FKIF 4OIOE 2JA5F 3S1QF 4Q4ZE 5IYDF 5M5XF 5FLMF 3S15F 4A3FF 4A3CF 5E18E 4X6AF 4G7ZE 2Y0SI 3WODE 3HOXF 4OINE 3GTLF 2A6HE 4BY7F 4GZYE 4ZH4E 1WCMF 4C2MF 3GTGF 5C4JF 5TMFE 4OIQE 4Y7NF 2NVTF 1I6HF 1R9TF 5IP7F 3S2HF 2E2JF
chains in the Genus database with same CATH superfamily
3DXJE 3GTOE 3H0GE 4YFNE 3GTJF 4A3JE 3S14F 3S1MF 2R7ZE 1TWCF 4A3BE 2JA7F 4BY1F 1I50F 4BBSF 2JA6E 4C3JF 3K7AF 1IW7E 4A3IE 5C44F 2E2JF 1K83F 4YG2E 2NVXE 3HOYF 5M5YE 5C3EE 4QIWH 3HOUF 3S2DE 5IYCF 1TWAE 2NVQE 5C4XF 1I3QE 3I4NE 3HOZE 2BE5E 4C3IE 2B63F 2R92F 2O5JE 3HOWF 2WAQH 3CQZE 4A3LF 2E2HF 1TWHF 3S1RF 3PO2F 5M3ME 4MQ9E 5IP9F 3S16E 2NVYF 5FJ8F 4A3KF 4A3MF 4A3EF 2PMZK 2Y0SH 5IYBE 1Y1WE 3GTKF 3GTQF 4G7OE 4LJZE 5D4EE 5C4JE 2CW0E 1Y1VE 3GTPF 3M4OF 3HOVE 2NVTE 2E2IF 4A93F 3M3YF 3PO3F 4A3DE 3GTMF 2YU9F 4A3GE 4C3HE 2R93F 4QIWK 2JA8E 1TWGF 3RZOE 5M3FF 4Y52F 3S17F 4KMUE 4LLGE 3RZDE 3S1NF 4BXXF 4BBRF 1TWFE 1SFOE 2WAQK 5M5WE 3FKIE 3S1QE 2A68E 2JA5E 4XLNE 5IYDE 5TMCE 5M5XE 5E17E 1YNNK 3GTOF 3H0GF 5IYCE 5FLME 4A3JF 4A3FE 3S15E 2R7ZF 4A3CE 3H3VF 3EQLE 4X6AE 2JA6F 1YNJK 5BYHE 3HOXE 4A3IF 1DZFA 3GTLE 4YFXE 2NVXF 4BY7E 1ZYRE 5M5YF 5C3EF 4XSZE 2WB1I 3S2DF 4AYBH 1WCME 4C2ME 3GTGE 1TWAF 4OIRE 5D4DE 1I6VE 2NVQF 1I3QF 3I4MF 3HOZF 1SMYE 4Y7NE 3I4NF 3HKZH 4C3IF 1I6HE 4A3EE 1R9TE 5IP7E 4XLPE 3S2HE 3CQZF 1HQME 4LK0E 5M3MF 5D4CE 2E2JE 2O5IE 2VUMF 3S14E 3GTJE 3S16F 5IPLE 4JK1E 3S1ME 1TWCE 2JA7E 4BY1E 1I50E 4KN7E 4KN4E 4BBSE 4OIPE 3K7AE 4C3JE 5IYBF 5C44E 1Y1WF 4LK1E 4XSXE 1QKLA 1K83E 3HOYE 2PPBE 2A69E 1Y1VF 4G7HE 3HOVF 3HOUE 4A3BF 5C4XE 4Q5SE 4YFKE 4MEXE 3H3VG 2A6EE 4A3DF 4A3GF 4C3HF 2JA8F 2B63E 2R92E 4AYBK 3RZOF 3HOWE 4A3LE 2E2HE 1TWHE 3RZDF 3S1RE 3PO2E 5IP9E 3HKZK 4MEYE 1TWFF 1SFOF 2NVYE 5FJ8E 4A3KE 1EIKA 5M5WF 3FKIF 2KRXA 2JA5F 4OIOE 4A3ME 3S1QF 4Q4ZE 5IYDF 5M5XF 3GTKE 3GTQE 5FLMF 3S15F 4A3FF 4A3CF 3I4ME 5E18E 3GTPE 3M4OE 4X6AF 2WB1H 4G7ZE 2Y0SI 3WODE 3HOXF 2E2IE 4A93E 4OINE 3GTLF 2A6HE 3M3YE 4BY7F 3GTME 3PO3E 2YU9E 2R93E 4GZYE 1TWGE 2VUME 4ZH4E 1WCMF 4C2MF 3GTGF 5M3FE 5C4JF 3S17E 4Y52E 5TMFE 4OIQE 4Y7NF 4BXXE 3S1NE 2NVTF 4BBRE 1I6HF 1R9TF 5IP7F 3S2HF 2PMZH
chains in the Genus database with same CATH topology
3DXJE 3S14F 3GTJF 4YFNE 3S1MF 1TWCF 2JA7F 4BY1F 1I50F 4BBSF 4C3JF 3K7AF 1IW7E 5C44F 1K83F 4YG2E 3HOYF 3HOUF 5IYCF 5C4XF 2BE5E 2B63F 2R92F 2O5JE 3HOWF 4A3LF 2E2HF 1TWHF 3S1RF 3PO2F 4MQ9E 5IP9F 2NVYF 5FJ8F 4A3KF 4A3MF 4A3EF 2PMZK 4G7OE 3GTKF 3GTQF 5D4EE 4LJZE 2CW0E 3GTPF 3M4OF 2E2IF 4A93F 3M3YF 3PO3F 3GTMF 2YU9F 2R93F 4QIWK 1TWGF 5M3FF 4Y52F 3S17F 4KMUE 4LLGE 3S1NF 4BXXF 4BBRF 2WAQK 2A68E 4XLNE 5TMCE 5E17E 1YNNK 3GTOF 3H0GF 4A3JF 2R7ZF 3EQLE 2JA6F 1YNJK 5BYHE 4A3IF 4YFXE 2NVXF 1ZYRE 5M5YF 5C3EF 4XSZE 2WB1I 3S2DF 1TWAF 4OIRE 5D4DE 1I6VE 2NVQF 1I3QF 3I4MF 3HOZF 1SMYE 3I4NF 4C3IF 4XLPE 3CQZF 1HQME 4LK0E 5M3MF 5D4CE 2O5IE 2VUMF 3S16F 5IPLE 4JK1E 4KN7E 4KN4E 4OIPE 5IYBF 1Y1WF 4LK1E 4XSXE 1QKLA 2PPBE 2A69E 1Y1VF 4G7HE 3HOVF 4A3BF 4Q5SE 4YFKE 4MEXE 3H3VG 2A6EE 4A3DF 4A3GF 4C3HF 2JA8F 4AYBK 3RZOF 3RZDF 3HKZK 4MEYE 1TWFF 1SFOF 5M5WF 3FKIF 2KRXA 2JA5F 4OIOE 3S1QF 4Q4ZE 5IYDF 5M5XF 5FLMF 3S15F 4A3FF 4A3CF 5E18E 4X6AF 4G7ZE 2Y0SI 3WODE 3HOXF 4OINE 3GTLF 2A6HE 4BY7F 4GZYE 4ZH4E 1WCMF 4C2MF 3GTGF 5C4JF 5TMFE 4OIQE 4Y7NF 2NVTF 1I6HF 1R9TF 5IP7F 3S2HF 2E2JF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DXJ E;  3S14 F;  3GTJ F;  4YFN E;  3S1M F;  1TWC F;  2JA7 F;  4BY1 F;  1I50 F;  4BBS F;  4C3J F;  3K7A F;  1IW7 E;  5C44 F;  1K83 F;  4YG2 E;  3HOY F;  3HOU F;  5IYC F;  5C4X F;  2BE5 E;  2B63 F;  2R92 F;  2O5J E;  3HOW F;  4A3L F;  2E2H F;  1TWH F;  3S1R F;  3PO2 F;  4MQ9 E;  5IP9 F;  2NVY F;  5FJ8 F;  4A3K F;  4A3M F;  4A3E F;  2PMZ K;  4G7O E;  3GTK F;  3GTQ F;  5D4E E;  4LJZ E;  2CW0 E;  3GTP F;  3M4O F;  2E2I F;  4A93 F;  3M3Y F;  3PO3 F;  3GTM F;  2YU9 F;  2R93 F;  1TWG F;  5M3F F;  4Y52 F;  3S17 F;  4KMU E;  4LLG E;  3S1N F;  4BXX F;  4BBR F;  2WAQ K;  2A68 E;  4XLN E;  5TMC E;  5E17 E;  1YNN K;  3GTO F;  3H0G F;  4A3J F;  2R7Z F;  3EQL E;  2JA6 F;  1YNJ K;  5BYH E;  4A3I F;  4YFX E;  2NVX F;  1ZYR E;  5M5Y F;  5C3E F;  4XSZ E;  2WB1 I;  3S2D F;  1TWA F;  4OIR E;  5D4D E;  1I6V E;  2NVQ F;  1I3Q F;  3I4M F;  3HOZ F;  1SMY E;  3I4N F;  4C3I F;  4XLP E;  3CQZ F;  1HQM E;  4LK0 E;  5M3M F;  5D4C E;  2O5I E;  2VUM F;  3S16 F;  5IPL E;  4JK1 E;  4KN7 E;  4KN4 E;  4OIP E;  5IYB F;  1Y1W F;  4LK1 E;  4XSX E;  1QKL A;  2PPB E;  2A69 E;  1Y1V F;  4G7H E;  3HOV F;  4A3B F;  4Q5S E;  4YFK E;  4MEX E;  3H3V G;  2A6E E;  4A3D F;  4A3G F;  4C3H F;  2JA8 F;  4AYB K;  3RZO F;  3RZD F;  3HKZ K;  4MEY E;  1TWF F;  1SFO F;  5M5W F;  3FKI F;  4OIO E;  2JA5 F;  3S1Q F;  4Q4Z E;  5IYD F;  5M5X F;  5FLM F;  3S15 F;  4A3F F;  4A3C F;  5E18 E;  4X6A F;  4G7Z E;  2Y0S I;  3WOD E;  3HOX F;  4OIN E;  3GTL F;  2A6H E;  4BY7 F;  4GZY E;  4ZH4 E;  1WCM F;  4C2M F;  3GTG F;  5C4J F;  5TMF E;  4OIQ E;  4Y7N F;  2NVT F;  1I6H F;  1R9T F;  5IP7 F;  3S2H F;  2E2J F; 
#chains in the Genus database with same CATH topology
 3DXJ E;  3GTO E;  3H0G E;  4YFN E;  3GTJ F;  4A3J E;  3S14 F;  3S1M F;  2R7Z E;  1TWC F;  4A3B E;  2JA7 F;  4BY1 F;  1I50 F;  4BBS F;  2JA6 E;  4C3J F;  3K7A F;  1IW7 E;  4A3I E;  5C44 F;  2E2J F;  1K83 F;  4YG2 E;  2NVX E;  3HOY F;  5M5Y E;  5C3E E;  4QIW H;  3HOU F;  3S2D E;  5IYC F;  1TWA E;  2NVQ E;  5C4X F;  1I3Q E;  3I4N E;  3HOZ E;  2BE5 E;  4C3I E;  2B63 F;  2R92 F;  2O5J E;  3HOW F;  2WAQ H;  3CQZ E;  4A3L F;  2E2H F;  1TWH F;  3S1R F;  3PO2 F;  5M3M E;  4MQ9 E;  5IP9 F;  3S16 E;  2NVY F;  5FJ8 F;  4A3K F;  4A3M F;  4A3E F;  2PMZ K;  2Y0S H;  5IYB E;  1Y1W E;  3GTK F;  3GTQ F;  4G7O E;  4LJZ E;  5D4E E;  5C4J E;  2CW0 E;  1Y1V E;  3GTP F;  3M4O F;  3HOV E;  2NVT E;  2E2I F;  4A93 F;  3M3Y F;  3PO3 F;  4A3D E;  3GTM F;  2YU9 F;  4A3G E;  4C3H E;  2R93 F;  4QIW K;  2JA8 E;  1TWG F;  3RZO E;  5M3F F;  4Y52 F;  3S17 F;  4KMU E;  4LLG E;  3RZD E;  3S1N F;  4BXX F;  4BBR F;  1TWF E;  1SFO E;  2WAQ K;  5M5W E;  3FKI E;  3S1Q E;  2A68 E;  2JA5 E;  4XLN E;  5IYD E;  5TMC E;  5M5X E;  5E17 E;  1YNN K;  3GTO F;  3H0G F;  5IYC E;  5FLM E;  4A3J F;  4A3F E;  3S15 E;  2R7Z F;  4A3C E;  3H3V F;  3EQL E;  4X6A E;  2JA6 F;  1YNJ K;  5BYH E;  3HOX E;  4A3I F;  1DZF A;  3GTL E;  4YFX E;  2NVX F;  4BY7 E;  1ZYR E;  5M5Y F;  5C3E F;  4XSZ E;  2WB1 I;  3S2D F;  4AYB H;  1WCM E;  4C2M E;  3GTG E;  1TWA F;  4OIR E;  5D4D E;  1I6V E;  2NVQ F;  1I3Q F;  3I4M F;  3HOZ F;  1SMY E;  4Y7N E;  3I4N F;  3HKZ H;  4C3I F;  1I6H E;  4A3E E;  1R9T E;  5IP7 E;  4XLP E;  3S2H E;  3CQZ F;  1HQM E;  4LK0 E;  5M3M F;  5D4C E;  2E2J E;  2O5I E;  2VUM F;  3S14 E;  3GTJ E;  3S16 F;  5IPL E;  4JK1 E;  3S1M E;  1TWC E;  2JA7 E;  4BY1 E;  1I50 E;  4KN7 E;  4KN4 E;  4BBS E;  4OIP E;  3K7A E;  4C3J E;  5IYB F;  5C44 E;  1Y1W F;  4LK1 E;  4XSX E;  1QKL A;  1K83 E;  3HOY E;  2PPB E;  2A69 E;  1Y1V F;  4G7H E;  3HOV F;  3HOU E;  4A3B F;  5C4X E;  4Q5S E;  4YFK E;  4MEX E;  3H3V G;  2A6E E;  4A3D F;  4A3G F;  4C3H F;  2JA8 F;  2B63 E;  2R92 E;  4AYB K;  3RZO F;  3HOW E;  4A3L E;  2E2H E;  1TWH E;  3RZD F;  3S1R E;  3PO2 E;  5IP9 E;  3HKZ K;  4MEY E;  1TWF F;  1SFO F;  2NVY E;  5FJ8 E;  4A3K E;  1EIK A;  5M5W F;  3FKI F;  2KRX A;  2JA5 F;  4OIO E;  4A3M E;  3S1Q F;  4Q4Z E;  5IYD F;  5M5X F;  3GTK E;  3GTQ E;  5FLM F;  3S15 F;  4A3F F;  4A3C F;  3I4M E;  5E18 E;  3GTP E;  3M4O E;  4X6A F;  2WB1 H;  4G7Z E;  2Y0S I;  3WOD E;  3HOX F;  2E2I E;  4A93 E;  4OIN E;  3GTL F;  2A6H E;  3M3Y E;  4BY7 F;  3GTM E;  3PO3 E;  2YU9 E;  2R93 E;  4GZY E;  1TWG E;  2VUM E;  4ZH4 E;  1WCM F;  4C2M F;  3GTG F;  5M3F E;  5C4J F;  3S17 E;  4Y52 E;  5TMF E;  4OIQ E;  4Y7N F;  4BXX E;  3S1N E;  2NVT F;  4BBR E;  1I6H F;  1R9T F;  5IP7 F;  3S2H F;  2PMZ H; 
#chains in the Genus database with same CATH homology
 3DXJ E;  3S14 F;  3GTJ F;  4YFN E;  3S1M F;  1TWC F;  2JA7 F;  4BY1 F;  1I50 F;  4BBS F;  4C3J F;  3K7A F;  1IW7 E;  5C44 F;  1K83 F;  4YG2 E;  3HOY F;  3HOU F;  5IYC F;  5C4X F;  2BE5 E;  2B63 F;  2R92 F;  2O5J E;  3HOW F;  4A3L F;  2E2H F;  1TWH F;  3S1R F;  3PO2 F;  4MQ9 E;  5IP9 F;  2NVY F;  5FJ8 F;  4A3K F;  4A3M F;  4A3E F;  2PMZ K;  4G7O E;  3GTK F;  3GTQ F;  5D4E E;  4LJZ E;  2CW0 E;  3GTP F;  3M4O F;  2E2I F;  4A93 F;  3M3Y F;  3PO3 F;  3GTM F;  2YU9 F;  2R93 F;  4QIW K;  1TWG F;  5M3F F;  4Y52 F;  3S17 F;  4KMU E;  4LLG E;  3S1N F;  4BXX F;  4BBR F;  2WAQ K;  2A68 E;  4XLN E;  5TMC E;  5E17 E;  1YNN K;  3GTO F;  3H0G F;  4A3J F;  2R7Z F;  3EQL E;  2JA6 F;  1YNJ K;  5BYH E;  4A3I F;  4YFX E;  2NVX F;  1ZYR E;  5M5Y F;  5C3E F;  4XSZ E;  2WB1 I;  3S2D F;  1TWA F;  4OIR E;  5D4D E;  1I6V E;  2NVQ F;  1I3Q F;  3I4M F;  3HOZ F;  1SMY E;  3I4N F;  4C3I F;  4XLP E;  3CQZ F;  1HQM E;  4LK0 E;  5M3M F;  5D4C E;  2O5I E;  2VUM F;  3S16 F;  5IPL E;  4JK1 E;  4KN7 E;  4KN4 E;  4OIP E;  5IYB F;  1Y1W F;  4LK1 E;  4XSX E;  1QKL A;  2PPB E;  2A69 E;  1Y1V F;  4G7H E;  3HOV F;  4A3B F;  4Q5S E;  4YFK E;  4MEX E;  3H3V G;  2A6E E;  4A3D F;  4A3G F;  4C3H F;  2JA8 F;  4AYB K;  3RZO F;  3RZD F;  3HKZ K;  4MEY E;  1TWF F;  1SFO F;  5M5W F;  3FKI F;  2KRX A;  2JA5 F;  4OIO E;  3S1Q F;  4Q4Z E;  5IYD F;  5M5X F;  5FLM F;  3S15 F;  4A3F F;  4A3C F;  5E18 E;  4X6A F;  4G7Z E;  2Y0S I;  3WOD E;  3HOX F;  4OIN E;  3GTL F;  2A6H E;  4BY7 F;  4GZY E;  4ZH4 E;  1WCM F;  4C2M F;  3GTG F;  5C4J F;  5TMF E;  4OIQ E;  4Y7N F;  2NVT F;  1I6H F;  1R9T F;  5IP7 F;  3S2H F;  2E2J F; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...