1T8NB

Crystal structure of the p1 thr bpti mutant- bovine chymotrypsin complex
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCTARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCLRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Bos taurus
publication title Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
pubmed doi rcsb
molecule keywords Chymotrypsin A
total genus 11
structure length 58
sequence length 58
chains with identical sequence D
ec nomenclature
pdb deposition date 2004-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1t8nB00
1UUBA 3BTMI 1EAWB 2DDIA 1TOCR 2PTCI 3AUEA 1CA0D 1EJMB 4DG4C 2ODYE 1JC6A 3BYBA 1T8OB 3AUBA 1D0DA 3TGII 3BTGI 1JV9A 3L33E 1BZ5A 2M01A 8PTIA 1JV8A 1SHPA 1KNTA 3UOUB 1G6XA 5PTIA 2J6DA 3FP7J 1PITA 1KIGI 3TPII 4U32X 1TFXC 2ZVXA 4BNRI 1ADZA 4Y0ZI 1KUNA 1P2KI 2LFLA 4Y11I 3BTQI 1P2II 4WWYC 4U30W 3U1JE 1F7ZI 2FI3I 4PTIA 1BIKA 2FI5I 1YKTB 3WNYA 3BTHI 1BF0A 1ZR0B 5JB5A 5JB6A 3AUHA 1OA55 2KAII 3LDJA 9PTIA 1BPTA 1YLCB 4WXVC 6PTIA 3CI7A 7PTIA 5JB4A 3FP8I 1DTXA 3T62D 2LFKA 1DEMA 1FANA 2TGPI 1T7CB 1CBWD 1TPAI 1QLQA 1BTHP 1FAKI 3TGKI 1P2MB 3D65I 4ISLB 5JB7A 3GYMI 3P95E 3UIRC 4TPII 1P2NB 2HEXA 2ZJXA 2TPII 1KTHA 1BRBI 1BUNB 1Y62A 1T8LB 1TCPA 2M99A 1LD5A 3FP6I 1BHCA 1BZXI 1YLDB 1TAPA 2RA3C 1P2JI 2UUXA 3AUDA 3AUGA 3L3TE 4NTYB 4BQDA 2KCRA 3P92E 3BTKI 1FY8I 4NTXB 4ISOB 1OA65 2JOTA 1DENA 1MTND 2DDJA 3AUCA 3BTWI 1T8MB 2FTLI 1CO7I 1NAGA 1YC0I 1T8NB 1B0CA 1AAPA 2IJOI 4NTWB 3M7QB 3TGJI 2FTMB 1P2QB 1IRHA 3OFWA 3BTDI 2UUYB 3BTFI 3AUIA 2KNTA 4BD9B 1P2OB 1UUAA 3BTEI 1BRCI 3LDMA 4Y0YI 1BPIA 1LD6A 4DTGK 2R9PE 1D0DB 5C67C 3OTJI 1BTIA 1AALA 1DTKA 1TAWB 1ZJDB 2FI4I 4ISNB 2CA7A 3BTTI 3LDIA 2W8XA 4Y10I 1F5RI 1K6UA
chains in the Genus database with same CATH superfamily
1UUBA 3BTMI 1EAWB 2DDIA 1TOCR 2PTCI 3AUEA 1CA0D 1EJMB 4DG4C 2ODYE 1JC6A 3BYBA 1T8OB 3AUBA 1D0DA 3TGII 3BTGI 1JV9A 3L33E 1BZ5A 2M01A 8PTIA 1JV8A 1SHPA 1KNTA 3UOUB 1G6XA 5PTIA 2J6DA 3FP7J 1PITA 1KIGI 3TPII 4U32X 1TFXC 2ZVXA 4BNRI 1ADZA 4Y0ZI 1KUNA 1P2KI 2LFLA 4Y11I 3BTQI 1P2II 4WWYC 4U30W 3U1JE 1F7ZI 2FI3I 4PTIA 1BIKA 2FI5I 1YKTB 3WNYA 3BTHI 1BF0A 1ZR0B 5JB5A 5JB6A 3AUHA 1OA55 2KAII 3LDJA 9PTIA 1BPTA 1YLCB 4WXVC 6PTIA 3CI7A 7PTIA 5JB4A 3FP8I 1DTXA 3T62D 2LFKA 1DEMA 1FANA 2TGPI 1T7CB 1CBWD 1TPAI 1QLQA 1BTHP 1FAKI 3TGKI 1P2MB 3D65I 4ISLB 5JB7A 3GYMI 3P95E 3UIRC 4TPII 1P2NB 2HEXA 2ZJXA 2TPII 1KTHA 1BRBI 1BUNB 1Y62A 1T8LB 1TCPA 2M99A 1LD5A 3FP6I 1BHCA 1BZXI 1YLDB 1TAPA 2RA3C 1P2JI 2UUXA 3AUDA 3AUGA 3L3TE 4NTYB 4BQDA 2KCRA 3P92E 3BTKI 1FY8I 4NTXB 4ISOB 1OA65 2JOTA 1DENA 1MTND 2DDJA 3AUCA 3BTWI 1T8MB 2FTLI 1CO7I 1NAGA 1YC0I 1T8NB 1B0CA 1AAPA 2IJOI 4NTWB 3M7QB 3TGJI 2FTMB 1P2QB 1IRHA 3OFWA 3BTDI 2UUYB 3BTFI 3AUIA 2KNTA 4BD9B 1P2OB 1UUAA 3BTEI 1BRCI 3LDMA 4Y0YI 1BPIA 1LD6A 4DTGK 2R9PE 1D0DB 5C67C 3OTJI 1BTIA 1AALA 1DTKA 1TAWB 1ZJDB 2FI4I 4ISNB 2CA7A 3BTTI 3LDIA 2W8XA 4Y10I 1F5RI 1K6UA
chains in the Genus database with same CATH topology
1UUBA 3BTMI 1EAWB 2DDIA 1TOCR 2PTCI 3AUEA 1CA0D 1EJMB 4DG4C 2ODYE 1JC6A 3BYBA 1T8OB 3AUBA 1D0DA 3TGII 3BTGI 1JV9A 3L33E 1BZ5A 2M01A 8PTIA 1JV8A 1SHPA 1KNTA 3UOUB 1G6XA 5PTIA 2J6DA 3FP7J 1PITA 1KIGI 3TPII 4U32X 1TFXC 2ZVXA 4BNRI 1ADZA 4Y0ZI 1KUNA 1P2KI 2LFLA 4Y11I 3BTQI 1P2II 4WWYC 4U30W 3U1JE 1F7ZI 2FI3I 4PTIA 1BIKA 2FI5I 1YKTB 3WNYA 3BTHI 1BF0A 1ZR0B 5JB5A 5JB6A 3AUHA 1OA55 2KAII 3LDJA 9PTIA 1BPTA 1YLCB 4WXVC 6PTIA 3CI7A 7PTIA 5JB4A 3FP8I 1DTXA 3T62D 2LFKA 1DEMA 1FANA 2TGPI 1T7CB 1CBWD 1TPAI 1QLQA 1BTHP 1FAKI 3TGKI 1P2MB 3D65I 4ISLB 5JB7A 3GYMI 3P95E 3UIRC 4TPII 1P2NB 2HEXA 2ZJXA 2TPII 1KTHA 1BRBI 1BUNB 1Y62A 1T8LB 1TCPA 2M99A 1LD5A 3FP6I 1BHCA 1BZXI 1YLDB 1TAPA 2RA3C 1P2JI 2UUXA 3AUDA 3AUGA 3L3TE 4NTYB 4BQDA 2KCRA 3P92E 3BTKI 1FY8I 4NTXB 4ISOB 1OA65 2JOTA 1DENA 1MTND 2DDJA 3AUCA 3BTWI 1T8MB 2FTLI 1CO7I 1NAGA 1YC0I 1T8NB 1B0CA 1AAPA 2IJOI 4NTWB 3M7QB 3TGJI 2FTMB 1P2QB 1IRHA 3OFWA 3BTDI 2UUYB 3BTFI 3AUIA 2KNTA 4BD9B 1P2OB 1UUAA 3BTEI 1BRCI 3LDMA 4Y0YI 1BPIA 1LD6A 4DTGK 2R9PE 1D0DB 5C67C 3OTJI 1BTIA 1AALA 1DTKA 1TAWB 1ZJDB 2FI4I 4ISNB 2CA7A 3BTTI 3LDIA 2W8XA 4Y10I 1F5RI 1K6UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UUB A;  3BTM I;  1EAW B;  2DDI A;  1TOC R;  2PTC I;  3AUE A;  1CA0 D;  1EJM B;  4DG4 C;  2ODY E;  1JC6 A;  3BYB A;  1T8O B;  3AUB A;  1D0D A;  3TGI I;  3BTG I;  1JV9 A;  3L33 E;  1BZ5 A;  2M01 A;  8PTI A;  1JV8 A;  1SHP A;  1KNT A;  3UOU B;  1G6X A;  5PTI A;  2J6D A;  3FP7 J;  1PIT A;  1KIG I;  3TPI I;  4U32 X;  1TFX C;  2ZVX A;  4BNR I;  1ADZ A;  4Y0Z I;  1KUN A;  1P2K I;  2LFL A;  4Y11 I;  3BTQ I;  1P2I I;  4WWY C;  4U30 W;  3U1J E;  1F7Z I;  2FI3 I;  4PTI A;  1BIK A;  2FI5 I;  1YKT B;  3WNY A;  3BTH I;  1BF0 A;  1ZR0 B;  5JB5 A;  5JB6 A;  3AUH A;  1OA5 5;  2KAI I;  3LDJ A;  9PTI A;  1BPT A;  1YLC B;  4WXV C;  6PTI A;  3CI7 A;  7PTI A;  5JB4 A;  3FP8 I;  1DTX A;  3T62 D;  2LFK A;  1DEM A;  1FAN A;  2TGP I;  1T7C B;  1CBW D;  1TPA I;  1QLQ A;  1BTH P;  1FAK I;  3TGK I;  1P2M B;  3D65 I;  4ISL B;  5JB7 A;  3GYM I;  3P95 E;  3UIR C;  4TPI I;  1P2N B;  2HEX A;  2ZJX A;  2TPI I;  1KTH A;  1BRB I;  1BUN B;  1Y62 A;  1T8L B;  1TCP A;  2M99 A;  1LD5 A;  3FP6 I;  1BHC A;  1BZX I;  1YLD B;  1TAP A;  2RA3 C;  1P2J I;  2UUX A;  3AUD A;  3AUG A;  3L3T E;  4NTY B;  4BQD A;  2KCR A;  3P92 E;  3BTK I;  1FY8 I;  4NTX B;  4ISO B;  1OA6 5;  2JOT A;  1DEN A;  1MTN D;  2DDJ A;  3AUC A;  3BTW I;  1T8M B;  2FTL I;  1CO7 I;  1NAG A;  1YC0 I;  1T8N B;  1B0C A;  1AAP A;  2IJO I;  4NTW B;  3M7Q B;  3TGJ I;  2FTM B;  1P2Q B;  1IRH A;  3OFW A;  3BTD I;  2UUY B;  3BTF I;  3AUI A;  2KNT A;  4BD9 B;  1P2O B;  1UUA A;  3BTE I;  1BRC I;  3LDM A;  4Y0Y I;  1BPI A;  1LD6 A;  4DTG K;  2R9P E;  1D0D B;  5C67 C;  3OTJ I;  1BTI A;  1AAL A;  1DTK A;  1TAW B;  1ZJD B;  2FI4 I;  4ISN B;  2CA7 A;  3BTT I;  3LDI A;  2W8X A;  4Y10 I;  1F5R I;  1K6U A; 
#chains in the Genus database with same CATH topology
 1UUB A;  3BTM I;  1EAW B;  2DDI A;  1TOC R;  2PTC I;  3AUE A;  1CA0 D;  1EJM B;  4DG4 C;  2ODY E;  1JC6 A;  3BYB A;  1T8O B;  3AUB A;  1D0D A;  3TGI I;  3BTG I;  1JV9 A;  3L33 E;  1BZ5 A;  2M01 A;  8PTI A;  1JV8 A;  1SHP A;  1KNT A;  3UOU B;  1G6X A;  5PTI A;  2J6D A;  3FP7 J;  1PIT A;  1KIG I;  3TPI I;  4U32 X;  1TFX C;  2ZVX A;  4BNR I;  1ADZ A;  4Y0Z I;  1KUN A;  1P2K I;  2LFL A;  4Y11 I;  3BTQ I;  1P2I I;  4WWY C;  4U30 W;  3U1J E;  1F7Z I;  2FI3 I;  4PTI A;  1BIK A;  2FI5 I;  1YKT B;  3WNY A;  3BTH I;  1BF0 A;  1ZR0 B;  5JB5 A;  5JB6 A;  3AUH A;  1OA5 5;  2KAI I;  3LDJ A;  9PTI A;  1BPT A;  1YLC B;  4WXV C;  6PTI A;  3CI7 A;  7PTI A;  5JB4 A;  3FP8 I;  1DTX A;  3T62 D;  2LFK A;  1DEM A;  1FAN A;  2TGP I;  1T7C B;  1CBW D;  1TPA I;  1QLQ A;  1BTH P;  1FAK I;  3TGK I;  1P2M B;  3D65 I;  4ISL B;  5JB7 A;  3GYM I;  3P95 E;  3UIR C;  4TPI I;  1P2N B;  2HEX A;  2ZJX A;  2TPI I;  1KTH A;  1BRB I;  1BUN B;  1Y62 A;  1T8L B;  1TCP A;  2M99 A;  1LD5 A;  3FP6 I;  1BHC A;  1BZX I;  1YLD B;  1TAP A;  2RA3 C;  1P2J I;  2UUX A;  3AUD A;  3AUG A;  3L3T E;  4NTY B;  4BQD A;  2KCR A;  3P92 E;  3BTK I;  1FY8 I;  4NTX B;  4ISO B;  1OA6 5;  2JOT A;  1DEN A;  1MTN D;  2DDJ A;  3AUC A;  3BTW I;  1T8M B;  2FTL I;  1CO7 I;  1NAG A;  1YC0 I;  1T8N B;  1B0C A;  1AAP A;  2IJO I;  4NTW B;  3M7Q B;  3TGJ I;  2FTM B;  1P2Q B;  1IRH A;  3OFW A;  3BTD I;  2UUY B;  3BTF I;  3AUI A;  2KNT A;  4BD9 B;  1P2O B;  1UUA A;  3BTE I;  1BRC I;  3LDM A;  4Y0Y I;  1BPI A;  1LD6 A;  4DTG K;  2R9P E;  1D0D B;  5C67 C;  3OTJ I;  1BTI A;  1AAL A;  1DTK A;  1TAW B;  1ZJD B;  2FI4 I;  4ISN B;  2CA7 A;  3BTT I;  3LDI A;  2W8X A;  4Y10 I;  1F5R I;  1K6U A; 
#chains in the Genus database with same CATH homology
 1UUB A;  3BTM I;  1EAW B;  2DDI A;  1TOC R;  2PTC I;  3AUE A;  1CA0 D;  1EJM B;  4DG4 C;  2ODY E;  1JC6 A;  3BYB A;  1T8O B;  3AUB A;  1D0D A;  3TGI I;  3BTG I;  1JV9 A;  3L33 E;  1BZ5 A;  2M01 A;  8PTI A;  1JV8 A;  1SHP A;  1KNT A;  3UOU B;  1G6X A;  5PTI A;  2J6D A;  3FP7 J;  1PIT A;  1KIG I;  3TPI I;  4U32 X;  1TFX C;  2ZVX A;  4BNR I;  1ADZ A;  4Y0Z I;  1KUN A;  1P2K I;  2LFL A;  4Y11 I;  3BTQ I;  1P2I I;  4WWY C;  4U30 W;  3U1J E;  1F7Z I;  2FI3 I;  4PTI A;  1BIK A;  2FI5 I;  1YKT B;  3WNY A;  3BTH I;  1BF0 A;  1ZR0 B;  5JB5 A;  5JB6 A;  3AUH A;  1OA5 5;  2KAI I;  3LDJ A;  9PTI A;  1BPT A;  1YLC B;  4WXV C;  6PTI A;  3CI7 A;  7PTI A;  5JB4 A;  3FP8 I;  1DTX A;  3T62 D;  2LFK A;  1DEM A;  1FAN A;  2TGP I;  1T7C B;  1CBW D;  1TPA I;  1QLQ A;  1BTH P;  1FAK I;  3TGK I;  1P2M B;  3D65 I;  4ISL B;  5JB7 A;  3GYM I;  3P95 E;  3UIR C;  4TPI I;  1P2N B;  2HEX A;  2ZJX A;  2TPI I;  1KTH A;  1BRB I;  1BUN B;  1Y62 A;  1T8L B;  1TCP A;  2M99 A;  1LD5 A;  3FP6 I;  1BHC A;  1BZX I;  1YLD B;  1TAP A;  2RA3 C;  1P2J I;  2UUX A;  3AUD A;  3AUG A;  3L3T E;  4NTY B;  4BQD A;  2KCR A;  3P92 E;  3BTK I;  1FY8 I;  4NTX B;  4ISO B;  1OA6 5;  2JOT A;  1DEN A;  1MTN D;  2DDJ A;  3AUC A;  3BTW I;  1T8M B;  2FTL I;  1CO7 I;  1NAG A;  1YC0 I;  1T8N B;  1B0C A;  1AAP A;  2IJO I;  4NTW B;  3M7Q B;  3TGJ I;  2FTM B;  1P2Q B;  1IRH A;  3OFW A;  3BTD I;  2UUY B;  3BTF I;  3AUI A;  2KNT A;  4BD9 B;  1P2O B;  1UUA A;  3BTE I;  1BRC I;  3LDM A;  4Y0Y I;  1BPI A;  1LD6 A;  4DTG K;  2R9P E;  1D0D B;  5C67 C;  3OTJ I;  1BTI A;  1AAL A;  1DTK A;  1TAW B;  1ZJD B;  2FI4 I;  4ISN B;  2CA7 A;  3BTT I;  3LDI A;  2W8X A;  4Y10 I;  1F5R I;  1K6U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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