1TWAF

Rna polymerase ii complexed with atp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
83
structure length
83
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 21
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1twaF00
4A3KF 4GZYE 3S2DF 5FJ8F 2Y0SI 2R92F 1K83F 2B63F 4BXXF 4BBRF 4ZH4E 4C3IF 5M5WF 4A3JF 2E2HF 4KN4E 3RZDF 3GTLF 3I4NF 5IP9F 3DXJE 4A3EF 4G7HE 5FLMF 4Y52F 3H3VG 1I3QF 4KMUE 3S1MF 2E2JF 1TWGF 4MEYE 4XLNE 3HOXF 4Q4ZE 2VUMF 5D4DE 2NVTF 3GTJF 2YU9F 4C2MF 3HKZK 4BBSF 5IYDF 4OIOE 2A6EE 5IP7F 2JA6F 4A3CF 4XLPE 4JK1E 5M5YF 3GTOF 2O5JE 3HOYF 3I4MF 1WCMF 2BE5E 1SFOF 1HQME 2CW0E 4YFNE 2R7ZF 4A3BF 3H0GF 5TMCE 1Y1WF 4XSZE 4BY7F 4G7ZE 4MEXE 3S2HF 5IYBF 1I50F 4Q5SE 1I6VE 4XSXE 4G7OE 5M3MF 3PO3F 4YG2E 2A69E 4A3GF 1TWFF 3FKIF 5E17E 2PPBE 2R93F 3GTQF 5E18E 4KN7E 3S16F 3GTGF 3S1NF 3RZOF 1SMYE 1TWAF 3M4OF 3S1RF 5C3EF 3GTKF 3HOVF 4YFXE 1QKLA 3CQZF 4OIRE 4A3LF 5BYHE 5C44F 5C4XF 4A3DF 1TWHF 4LK1E 4A93F 3S14F 1Y1VF 4LLGE 4A3MF 3WODE 5M5XF 3K7AF 5IYCF 5M3FF 2JA5F 4X6AF 3S17F 5D4CE 2WB1I 4A3FF 1YNJK 5IPLE 4AYBK 1YNNK 3S15F 4OIQE 3M3YF 4C3JF 3GTMF 3GTPF 4LJZE 4LK0E 4C3HF 4A3IF 2O5IE 4YFKE 3S1QF 2NVXF 3HOUF 1R9TF 1IW7E 1I6HF 4OIPE 2A68E 2JA8F 3HOZF 2NVYF 4Y7NF 2WAQK 4OINE 4BY1F 2JA7F 1ZYRE 5C4JF 3HOWF 1TWCF 2PMZK 5D4EE 4MQ9E 5TMFE 3PO2F 2NVQF 2A6HE 3EQLE 2E2IF
chains in the Genus database with same CATH superfamily
1TWHE 4A3KF 4A93E 4GZYE 3S14E 1Y1VE 3S2DF 5FJ8F 4A3ME 2Y0SI 2R92F 1K83F 2B63F 2WB1H 4BXXF 3K7AE 5IYCE 4BBRF 4ZH4E 4C3IF 5M5WF 5M3FE 4A3JF 3PO3E 4X6AE 2E2HF 3S17E 4KN4E 4A3FE 3RZDF 3GTLF 3I4NF 3FKIE 5IP9F 3DXJE 4A3EF 3M3YE 4C3JE 4G7HE 5FLMF 4Y52F 3GTME 3H3VG 1I3QF 3GTPE 4KMUE 3S1MF 4A3IE 2KRXA 2E2JF 3S1QE 1TWGF 2NVXE 4MEYE 4XLNE 3HOXF 3HOUE 4Q4ZE 2VUMF 5D4DE 1R9TE 2NVTF 4AYBH 3GTJF 2YU9F 1I6HE 4C2MF 2JA8E 2NVYE 3HKZK 4BBSF 5IYDF 4A3DE 4OIOE 2A6EE 5IP7F 2JA6F 2JA7E 4A3CF 3HOWE 4XLPE 1TWCE 4JK1E 5M5YF 3GTOF 2O5JE 3PO2E 2NVQE 5M5XE 3HOYF 3HOZE 3I4MF 2JA5E 2Y0SH 1WCMF 2BE5E 1SFOF 4A3KE 3S2DE 1HQME 2CW0E 2WAQH 4YFNE 5FJ8E 2R7ZF 3H0GF 3S15E 4A3BF 1K83E 2R92E 5TMCE 1Y1WF 4XSZE 4BY7F 4C3HE 4G7ZE 4MEXE 2B63E 4BBRE 3S2HF 4C3IE 5M5WE 4BXXE 4A3JE 5IYBF 1I50F 2E2HE 4Q5SE 1I6VE 4XSXE 3RZDE 3GTLE 3I4NE 4G7OE 5M3MF 5IP9E 4A3EE 3PO3F 5FLME 4YG2E 4Y52E 1I3QE 2A69E 4A3GF 3S1ME 1TWFF 3FKIF 5E17E 2E2JE 2PPBE 2R93F 1TWGE 4Y7NE 3GTQF 3HOXE 5E18E 4KN7E 3S16F 4BY1E 5C4JE 2VUME 3GTGF 3S1NF 4QIWH 2NVTE 3RZOF 3GTJE 2YU9E 1SMYE 1DZFA 1TWAF 4C2ME 3M4OF 3S1RF 4BBSE 5C3EF 3GTKF 2E2IE 5IYDE 3HOVF 4YFXE 5IP7E 2JA6E 4A3CE 1QKLA 3H3VF 3CQZF 4OIRE 4A3LF 5BYHE 5M5YE 3GTOE 5C44F 5C4XF 4A3DF 1TWHF 4LK1E 4A93F 2PMZH 3HOYE 3S14F 1Y1VF 4LLGE 4A3MF 3I4ME 1WCME 1SFOE 3WODE 5M5XF 3HKZH 3K7AF 5IYCF 2R7ZE 4A3BE 5M3FF 2JA5F 3H0GE 4X6AF 1Y1WE 5D4CE 2WB1I 4A3FF 3S17F 1YNJK 3S2HE 4BY7E 4AYBK 5IPLE 1YNNK 3S15F 4OIQE 5IYBE 1I50E 4C3JF 3GTMF 3M3YF 3GTPF 4LJZE 4LK0E 4C3HF 5M3ME 5C4XE 4A3IF 2O5IE 4YFKE 3S1QF 2NVXF 4QIWK 3HOUF 4A3GE 1TWFE 2R93E 1EIKA 1R9TF 3GTQE 3S16E 1IW7E 1I6HF 4OIPE 2A68E 2JA8F 3GTGE 2NVYF 3HOZF 3S1NE 4Y7NF 2WAQK 3RZOE 4OINE 4BY1F 1TWAE 2JA7F 1ZYRE 5C4JF 3HOWF 1TWCF 3S1RE 2PMZK 5C3EE 3GTKE 5D4EE 4MQ9E 3M4OE 3HOVE 5TMFE 3PO2F 2NVQF 3CQZE 2A6HE 4A3LE 3EQLE 5C44E 2E2IF
chains in the Genus database with same CATH topology
4A3KF 4GZYE 3S2DF 5FJ8F 2Y0SI 2R92F 1K83F 2B63F 4BXXF 4BBRF 4ZH4E 4C3IF 5M5WF 4A3JF 2E2HF 4KN4E 3RZDF 3GTLF 3I4NF 5IP9F 3DXJE 4A3EF 4G7HE 5FLMF 4Y52F 3H3VG 1I3QF 4KMUE 3S1MF 2KRXA 2E2JF 1TWGF 4MEYE 4XLNE 3HOXF 4Q4ZE 2VUMF 5D4DE 2NVTF 3GTJF 2YU9F 4C2MF 3HKZK 4BBSF 5IYDF 4OIOE 2A6EE 5IP7F 2JA6F 4A3CF 4XLPE 4JK1E 5M5YF 3GTOF 2O5JE 3HOYF 3I4MF 1WCMF 2BE5E 1SFOF 1HQME 2CW0E 4YFNE 2R7ZF 4A3BF 3H0GF 5TMCE 1Y1WF 4XSZE 4BY7F 4G7ZE 4MEXE 3S2HF 5IYBF 1I50F 4Q5SE 1I6VE 4XSXE 4G7OE 5M3MF 3PO3F 4YG2E 2A69E 4A3GF 1TWFF 3FKIF 5E17E 2PPBE 2R93F 3GTQF 5E18E 4KN7E 3S16F 3GTGF 3S1NF 3RZOF 1SMYE 1TWAF 3M4OF 3S1RF 5C3EF 3GTKF 3HOVF 4YFXE 1QKLA 3CQZF 4OIRE 4A3LF 5BYHE 5C44F 5C4XF 4A3DF 1TWHF 4LK1E 4A93F 3S14F 1Y1VF 4LLGE 4A3MF 3WODE 5M5XF 3K7AF 5IYCF 5M3FF 2JA5F 4X6AF 3S17F 5D4CE 2WB1I 4A3FF 1YNJK 5IPLE 4AYBK 1YNNK 3S15F 4OIQE 3M3YF 4C3JF 3GTMF 3GTPF 4LJZE 4LK0E 4C3HF 4A3IF 2O5IE 4YFKE 3S1QF 2NVXF 4QIWK 3HOUF 1R9TF 1IW7E 1I6HF 4OIPE 2A68E 2JA8F 3HOZF 2NVYF 4Y7NF 2WAQK 4OINE 4BY1F 2JA7F 1ZYRE 5C4JF 3HOWF 1TWCF 2PMZK 5D4EE 4MQ9E 5TMFE 3PO2F 2NVQF 2A6HE 3EQLE 2E2IF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3K F;  4GZY E;  3S2D F;  5FJ8 F;  2Y0S I;  2R92 F;  1K83 F;  2B63 F;  4BXX F;  4BBR F;  4ZH4 E;  4C3I F;  5M5W F;  4A3J F;  2E2H F;  4KN4 E;  3RZD F;  3GTL F;  3I4N F;  5IP9 F;  3DXJ E;  4A3E F;  4G7H E;  5FLM F;  4Y52 F;  3H3V G;  1I3Q F;  4KMU E;  3S1M F;  2E2J F;  1TWG F;  4MEY E;  4XLN E;  3HOX F;  4Q4Z E;  2VUM F;  5D4D E;  2NVT F;  3GTJ F;  2YU9 F;  4C2M F;  3HKZ K;  4BBS F;  5IYD F;  4OIO E;  2A6E E;  5IP7 F;  2JA6 F;  4A3C F;  4XLP E;  4JK1 E;  5M5Y F;  3GTO F;  2O5J E;  3HOY F;  3I4M F;  1WCM F;  2BE5 E;  1SFO F;  1HQM E;  2CW0 E;  4YFN E;  2R7Z F;  4A3B F;  3H0G F;  5TMC E;  1Y1W F;  4XSZ E;  4BY7 F;  4G7Z E;  4MEX E;  3S2H F;  5IYB F;  1I50 F;  4Q5S E;  1I6V E;  4XSX E;  4G7O E;  5M3M F;  3PO3 F;  4YG2 E;  2A69 E;  4A3G F;  1TWF F;  3FKI F;  5E17 E;  2PPB E;  2R93 F;  3GTQ F;  5E18 E;  4KN7 E;  3S16 F;  3GTG F;  3S1N F;  3RZO F;  1SMY E;  1TWA F;  3M4O F;  3S1R F;  5C3E F;  3GTK F;  3HOV F;  4YFX E;  1QKL A;  3CQZ F;  4OIR E;  4A3L F;  5BYH E;  5C44 F;  5C4X F;  4A3D F;  1TWH F;  4LK1 E;  4A93 F;  3S14 F;  1Y1V F;  4LLG E;  4A3M F;  3WOD E;  5M5X F;  3K7A F;  5IYC F;  5M3F F;  2JA5 F;  4X6A F;  3S17 F;  5D4C E;  2WB1 I;  4A3F F;  1YNJ K;  5IPL E;  4AYB K;  1YNN K;  3S15 F;  4OIQ E;  3M3Y F;  4C3J F;  3GTM F;  3GTP F;  4LJZ E;  4LK0 E;  4C3H F;  4A3I F;  2O5I E;  4YFK E;  3S1Q F;  2NVX F;  3HOU F;  1R9T F;  1IW7 E;  1I6H F;  4OIP E;  2A68 E;  2JA8 F;  3HOZ F;  2NVY F;  4Y7N F;  2WAQ K;  4OIN E;  4BY1 F;  2JA7 F;  1ZYR E;  5C4J F;  3HOW F;  1TWC F;  2PMZ K;  5D4E E;  4MQ9 E;  5TMF E;  3PO2 F;  2NVQ F;  2A6H E;  3EQL E;  2E2I F; 
#chains in the Genus database with same CATH topology
 1TWH E;  4A3K F;  4A93 E;  4GZY E;  3S14 E;  1Y1V E;  3S2D F;  5FJ8 F;  4A3M E;  2Y0S I;  2R92 F;  1K83 F;  2B63 F;  2WB1 H;  4BXX F;  3K7A E;  5IYC E;  4BBR F;  4ZH4 E;  4C3I F;  5M5W F;  5M3F E;  4A3J F;  3PO3 E;  4X6A E;  2E2H F;  3S17 E;  4KN4 E;  4A3F E;  3RZD F;  3GTL F;  3I4N F;  3FKI E;  5IP9 F;  3DXJ E;  4A3E F;  3M3Y E;  4C3J E;  4G7H E;  5FLM F;  4Y52 F;  3GTM E;  3H3V G;  1I3Q F;  3GTP E;  4KMU E;  3S1M F;  4A3I E;  2KRX A;  2E2J F;  3S1Q E;  1TWG F;  2NVX E;  4MEY E;  4XLN E;  3HOX F;  3HOU E;  4Q4Z E;  2VUM F;  5D4D E;  1R9T E;  2NVT F;  4AYB H;  3GTJ F;  2YU9 F;  1I6H E;  4C2M F;  2JA8 E;  2NVY E;  3HKZ K;  4BBS F;  5IYD F;  4A3D E;  4OIO E;  2A6E E;  5IP7 F;  2JA6 F;  2JA7 E;  4A3C F;  3HOW E;  4XLP E;  1TWC E;  4JK1 E;  5M5Y F;  3GTO F;  2O5J E;  3PO2 E;  2NVQ E;  5M5X E;  3HOY F;  3HOZ E;  3I4M F;  2JA5 E;  2Y0S H;  1WCM F;  2BE5 E;  1SFO F;  4A3K E;  3S2D E;  1HQM E;  2CW0 E;  2WAQ H;  4YFN E;  5FJ8 E;  2R7Z F;  3H0G F;  3S15 E;  4A3B F;  1K83 E;  2R92 E;  5TMC E;  1Y1W F;  4XSZ E;  4BY7 F;  4C3H E;  4G7Z E;  4MEX E;  2B63 E;  4BBR E;  3S2H F;  4C3I E;  5M5W E;  4BXX E;  4A3J E;  5IYB F;  1I50 F;  2E2H E;  4Q5S E;  1I6V E;  4XSX E;  3RZD E;  3GTL E;  3I4N E;  4G7O E;  5M3M F;  5IP9 E;  4A3E E;  3PO3 F;  5FLM E;  4YG2 E;  4Y52 E;  1I3Q E;  2A69 E;  4A3G F;  3S1M E;  1TWF F;  3FKI F;  5E17 E;  2E2J E;  2PPB E;  2R93 F;  1TWG E;  4Y7N E;  3GTQ F;  3HOX E;  5E18 E;  4KN7 E;  3S16 F;  4BY1 E;  5C4J E;  2VUM E;  3GTG F;  3S1N F;  4QIW H;  2NVT E;  3RZO F;  3GTJ E;  2YU9 E;  1SMY E;  1DZF A;  1TWA F;  4C2M E;  3M4O F;  3S1R F;  4BBS E;  5C3E F;  3GTK F;  2E2I E;  5IYD E;  3HOV F;  4YFX E;  5IP7 E;  2JA6 E;  4A3C E;  1QKL A;  3H3V F;  3CQZ F;  4OIR E;  4A3L F;  5BYH E;  5M5Y E;  3GTO E;  5C44 F;  5C4X F;  4A3D F;  1TWH F;  4LK1 E;  4A93 F;  2PMZ H;  3HOY E;  3S14 F;  1Y1V F;  4LLG E;  4A3M F;  3I4M E;  1WCM E;  1SFO E;  3WOD E;  5M5X F;  3HKZ H;  3K7A F;  5IYC F;  2R7Z E;  4A3B E;  5M3F F;  2JA5 F;  3H0G E;  4X6A F;  1Y1W E;  5D4C E;  2WB1 I;  4A3F F;  3S17 F;  1YNJ K;  3S2H E;  4BY7 E;  4AYB K;  5IPL E;  1YNN K;  3S15 F;  4OIQ E;  5IYB E;  1I50 E;  4C3J F;  3GTM F;  3M3Y F;  3GTP F;  4LJZ E;  4LK0 E;  4C3H F;  5M3M E;  5C4X E;  4A3I F;  2O5I E;  4YFK E;  3S1Q F;  2NVX F;  4QIW K;  3HOU F;  4A3G E;  1TWF E;  2R93 E;  1EIK A;  1R9T F;  3GTQ E;  3S16 E;  1IW7 E;  1I6H F;  4OIP E;  2A68 E;  2JA8 F;  3GTG E;  2NVY F;  3HOZ F;  3S1N E;  4Y7N F;  2WAQ K;  3RZO E;  4OIN E;  4BY1 F;  1TWA E;  2JA7 F;  1ZYR E;  5C4J F;  3HOW F;  1TWC F;  3S1R E;  2PMZ K;  5C3E E;  3GTK E;  5D4E E;  4MQ9 E;  3M4O E;  3HOV E;  5TMF E;  3PO2 F;  2NVQ F;  3CQZ E;  2A6H E;  4A3L E;  3EQL E;  5C44 E;  2E2I F; 
#chains in the Genus database with same CATH homology
 4A3K F;  4GZY E;  3S2D F;  5FJ8 F;  2Y0S I;  2R92 F;  1K83 F;  2B63 F;  4BXX F;  4BBR F;  4ZH4 E;  4C3I F;  5M5W F;  4A3J F;  2E2H F;  4KN4 E;  3RZD F;  3GTL F;  3I4N F;  5IP9 F;  3DXJ E;  4A3E F;  4G7H E;  5FLM F;  4Y52 F;  3H3V G;  1I3Q F;  4KMU E;  3S1M F;  2KRX A;  2E2J F;  1TWG F;  4MEY E;  4XLN E;  3HOX F;  4Q4Z E;  2VUM F;  5D4D E;  2NVT F;  3GTJ F;  2YU9 F;  4C2M F;  3HKZ K;  4BBS F;  5IYD F;  4OIO E;  2A6E E;  5IP7 F;  2JA6 F;  4A3C F;  4XLP E;  4JK1 E;  5M5Y F;  3GTO F;  2O5J E;  3HOY F;  3I4M F;  1WCM F;  2BE5 E;  1SFO F;  1HQM E;  2CW0 E;  4YFN E;  2R7Z F;  4A3B F;  3H0G F;  5TMC E;  1Y1W F;  4XSZ E;  4BY7 F;  4G7Z E;  4MEX E;  3S2H F;  5IYB F;  1I50 F;  4Q5S E;  1I6V E;  4XSX E;  4G7O E;  5M3M F;  3PO3 F;  4YG2 E;  2A69 E;  4A3G F;  1TWF F;  3FKI F;  5E17 E;  2PPB E;  2R93 F;  3GTQ F;  5E18 E;  4KN7 E;  3S16 F;  3GTG F;  3S1N F;  3RZO F;  1SMY E;  1TWA F;  3M4O F;  3S1R F;  5C3E F;  3GTK F;  3HOV F;  4YFX E;  1QKL A;  3CQZ F;  4OIR E;  4A3L F;  5BYH E;  5C44 F;  5C4X F;  4A3D F;  1TWH F;  4LK1 E;  4A93 F;  3S14 F;  1Y1V F;  4LLG E;  4A3M F;  3WOD E;  5M5X F;  3K7A F;  5IYC F;  5M3F F;  2JA5 F;  4X6A F;  3S17 F;  5D4C E;  2WB1 I;  4A3F F;  1YNJ K;  5IPL E;  4AYB K;  1YNN K;  3S15 F;  4OIQ E;  3M3Y F;  4C3J F;  3GTM F;  3GTP F;  4LJZ E;  4LK0 E;  4C3H F;  4A3I F;  2O5I E;  4YFK E;  3S1Q F;  2NVX F;  4QIW K;  3HOU F;  1R9T F;  1IW7 E;  1I6H F;  4OIP E;  2A68 E;  2JA8 F;  3HOZ F;  2NVY F;  4Y7N F;  2WAQ K;  4OIN E;  4BY1 F;  2JA7 F;  1ZYR E;  5C4J F;  3HOW F;  1TWC F;  2PMZ K;  5D4E E;  4MQ9 E;  5TMF E;  3PO2 F;  2NVQ F;  2A6H E;  3EQL E;  2E2I F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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