1TWCF

Rna polymerase ii complexed with gtp
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
83
structure length
83
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 23
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1twcF00
4BY7F 5M5XF 5M5WF 3RZDF 2R93F 5C4XF 4OINE 4JK1E 4LK0E 3H3VG 4C2MF 3GTKF 1HQME 3DXJE 2A68E 4A3JF 3GTMF 3HOYF 3WODE 4OIQE 4BBRF 4XSZE 3PO2F 4AYBK 2O5IE 4LLGE 3S1QF 1QKLA 1Y1WF 4A3CF 5IP7F 3GTGF 3S17F 2PPBE 3S2HF 4XLNE 3GTLF 3HOWF 1Y1VF 4BBSF 4XLPE 2O5JE 4MEXE 2JA7F 4LK1E 4XSXE 4Q4ZE 3S1NF 1TWHF 2A6EE 2WAQK 3I4MF 4X6AF 3I4NF 4ZH4E 5IYCF 1TWGF 2A6HE 5D4CE 4MEYE 1I6VE 4A93F 5C44F 1SMYE 1I50F 5TMCE 2VUMF 4YG2E 3M3YF 4OIOE 4MQ9E 5C4JF 3GTQF 3CQZF 1I3QF 5IYDF 4KN4E 2R7ZF 4C3HF 2R92F 4A3FF 3S1RF 1ZYRE 4YFNE 3FKIF 2PMZK 5IYBF 3HOVF 4BY1F 2NVYF 3S16F 4A3IF 3PO3F 5TMFE 1R9TF 2NVQF 4A3LF 3S1MF 4Q5SE 2JA6F 5M3FF 2BE5E 5C3EF 4A3BF 4A3DF 3GTPF 4A3MF 4BXXF 5E18E 2E2IF 4A3KF 4A3EF 2A69E 3EQLE 2E2JF 5M5YF 4YFXE 4Y52F 3H0GF 2WB1I 4KN7E 2CW0E 3M4OF 2E2HF 3S14F 5BYHE 4G7HE 4GZYE 2NVXF 5M3MF 4OIRE 3HKZK 5IP9F 1TWAF 4G7ZE 4C3IF 4Y7NF 5IPLE 5D4EE 3HOXF 2YU9F 3GTJF 3HOUF 1K83F 1TWCF 2JA5F 1YNNK 2JA8F 3HOZF 2Y0SI 2B63F 2NVTF 1WCMF 4LJZE 4A3GF 5FLMF 1I6HF 5D4DE 3GTOF 3S2DF 3K7AF 1YNJK 4C3JF 1SFOF 4G7OE 1IW7E 1TWFF 3RZOF 5FJ8F 3S15F 5E17E 4OIPE 4YFKE 4KMUE
chains in the Genus database with same CATH superfamily
4BY7F 5M5XF 5M5WF 5C3EE 2KRXA 3RZDF 2NVTE 4A3BE 2R93F 4A3DE 5C4XF 4OINE 3GTPE 4JK1E 4LK0E 5FLME 4A3ME 4C2MF 3GTKF 3H3VG 1HQME 3DXJE 4BXXE 4A3KE 4A3EE 2A68E 4A3JF 2E2JE 3GTMF 5M5YE 3HOYF 3WODE 4OIQE 4BBRF 4XSZE 3PO2F 4Y52E 4AYBK 3H0GE 2O5IE 4LLGE 3M4OE 2E2HE 3S1QF 1QKLA 1Y1WF 2NVXE 5IP7F 4A3CF 4AYBH 5M3ME 3GTGF 5IP9E 1TWAE 2PPBE 4C3IE 3S17F 4Y7NE 3S2HF 5M5XE 4XLNE 3HOXE 3GTJE 3RZDE 2YU9E 3GTLF 1K83E 1TWCE 1Y1VF 3HOUE 3HOWF 4BBSF 4XLPE 1DZFA 2JA5E 2O5JE 2JA8E 4MEXE 2JA7F 2B63E 4LK1E 3GTME 1WCME 4XSXE 4Q4ZE 4A3GE 3S1NF 1I6HE 1TWHF 2A6EE 2WAQK 3I4MF 4X6AF 3I4NF 4ZH4E 3GTOE 3S2DE 3K7AE 5IYCF 1TWGF 1SFOE 2A6HE 2WAQH 4MEYE 1I6VE 4C3JE 5D4CE 5C44F 4A93F 1SMYE 1I50F 5TMCE 2VUMF 4YG2E 3M3YF 4OIOE 1TWFE 4MQ9E 5C4JF 3GTQF 3CQZF 3RZOE 5FJ8E 3S15E 1I3QF 5IYDF 4KN4E 2R7ZF 4C3HF 3HOZE 4BY7E 2R92F 4A3FF 3S1RF 1ZYRE 4YFNE 3FKIF 2PMZK 5M5WE 5IYBF 3HOVF 2R93E 4BY1F 5C4XE 2NVYF 3S16F 4C2ME 4A3IF 5TMFE 1R9TF 3GTKE 2NVQF 3PO3F 4A3LF 2PMZH 3S1MF 4A3JE 4Q5SE 2JA6F 5M3FF 2BE5E 3HOYE 5M3FE 5IYCE 5C3EF 3H3VF 2WB1H 4A3BF 4A3DF 4BBRE 3GTPF 3PO2E 4A3MF 4BXXF 1EIKA 5E18E 2E2IF 4A3KF 4A3EF 2A69E 3EQLE 3M3YE 3S1QE 1Y1WE 2E2JF 3CQZE 5IP7E 5M5YF 4A3CE 3GTGE 3S17E 4YFXE 3S2HE 4C3HE 4Y52F 3H0GF 2WB1I 4KN7E 2CW0E 4QIWK 3GTLE 3HOWE 2E2HF 3M4OF 3S14F 1Y1VE 4BY1E 4BBSE 5BYHE 4G7HE 4GZYE 2Y0SH 2NVXF 5M3MF 4OIRE 3HKZK 5IP9F 1TWAF 4QIWH 4C3IF 4G7ZE 3S1ME 4Y7NF 2JA7E 5IPLE 5D4EE 3HOXF 2YU9F 3GTJF 3HOUF 3HKZH 1K83F 1TWCF 3S1NE 1TWHE 2JA5F 1YNNK 3I4ME 2JA8F 2E2IE 3I4NE 3HOZF 4X6AE 2Y0SI 2B63F 2NVTF 1WCMF 1TWGE 4LJZE 4A93E 4A3GF 5C44E 5FLMF 1I6HF 1I50E 2VUME 5D4DE 3GTQE 5C4JE 3GTOF 3S14E 2JA6E 3K7AF 3S2DF 1I3QE 1YNJK 5IYDE 4C3JF 1SFOF 2R7ZE 2R92E 4A3FE 3S1RE 3FKIE 3HOVE 5IYBE 4G7OE 1IW7E 1TWFF 2NVYE 3RZOF 3S16E 4A3IE 3PO3E 5FJ8F 1R9TE 3S15F 2NVQE 5E17E 4A3LE 4OIPE 4YFKE 4KMUE
chains in the Genus database with same CATH topology
4BY7F 5M5XF 5M5WF 3RZDF 2KRXA 2R93F 5C4XF 4OINE 4JK1E 4LK0E 3H3VG 4C2MF 3GTKF 1HQME 3DXJE 2A68E 4A3JF 3GTMF 3HOYF 3WODE 4OIQE 4BBRF 4XSZE 3PO2F 4AYBK 2O5IE 4LLGE 3S1QF 1QKLA 1Y1WF 4A3CF 5IP7F 3GTGF 3S17F 2PPBE 3S2HF 4XLNE 3GTLF 3HOWF 1Y1VF 4BBSF 4XLPE 2O5JE 4MEXE 2JA7F 4LK1E 4XSXE 4Q4ZE 3S1NF 1TWHF 2A6EE 2WAQK 3I4MF 4X6AF 3I4NF 4ZH4E 5IYCF 1TWGF 2A6HE 5D4CE 4MEYE 1I6VE 4A93F 5C44F 1SMYE 1I50F 5TMCE 2VUMF 4YG2E 3M3YF 4OIOE 4MQ9E 5C4JF 3GTQF 3CQZF 1I3QF 5IYDF 4KN4E 2R7ZF 4C3HF 2R92F 4A3FF 3S1RF 1ZYRE 4YFNE 3FKIF 2PMZK 5IYBF 3HOVF 4BY1F 2NVYF 3S16F 4A3IF 3PO3F 5TMFE 1R9TF 2NVQF 4A3LF 3S1MF 4Q5SE 2JA6F 5M3FF 2BE5E 5C3EF 4A3BF 4A3DF 3GTPF 4A3MF 4BXXF 5E18E 2E2IF 4A3KF 4A3EF 2A69E 3EQLE 2E2JF 5M5YF 4YFXE 4Y52F 3H0GF 2WB1I 4KN7E 2CW0E 4QIWK 3M4OF 2E2HF 3S14F 5BYHE 4G7HE 4GZYE 2NVXF 5M3MF 4OIRE 3HKZK 5IP9F 1TWAF 4G7ZE 4C3IF 4Y7NF 5IPLE 5D4EE 3HOXF 2YU9F 3GTJF 3HOUF 1K83F 1TWCF 2JA5F 1YNNK 2JA8F 3HOZF 2Y0SI 2B63F 2NVTF 1WCMF 4LJZE 4A3GF 5FLMF 1I6HF 5D4DE 3GTOF 3S2DF 3K7AF 1YNJK 4C3JF 1SFOF 4G7OE 1IW7E 1TWFF 3RZOF 5FJ8F 3S15F 5E17E 4OIPE 4YFKE 4KMUE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BY7 F;  5M5X F;  5M5W F;  3RZD F;  2R93 F;  5C4X F;  4OIN E;  4JK1 E;  4LK0 E;  3H3V G;  4C2M F;  3GTK F;  1HQM E;  3DXJ E;  2A68 E;  4A3J F;  3GTM F;  3HOY F;  3WOD E;  4OIQ E;  4BBR F;  4XSZ E;  3PO2 F;  4AYB K;  2O5I E;  4LLG E;  3S1Q F;  1QKL A;  1Y1W F;  4A3C F;  5IP7 F;  3GTG F;  3S17 F;  2PPB E;  3S2H F;  4XLN E;  3GTL F;  3HOW F;  1Y1V F;  4BBS F;  4XLP E;  2O5J E;  4MEX E;  2JA7 F;  4LK1 E;  4XSX E;  4Q4Z E;  3S1N F;  1TWH F;  2A6E E;  2WAQ K;  3I4M F;  4X6A F;  3I4N F;  4ZH4 E;  5IYC F;  1TWG F;  2A6H E;  5D4C E;  4MEY E;  1I6V E;  4A93 F;  5C44 F;  1SMY E;  1I50 F;  5TMC E;  2VUM F;  4YG2 E;  3M3Y F;  4OIO E;  4MQ9 E;  5C4J F;  3GTQ F;  3CQZ F;  1I3Q F;  5IYD F;  4KN4 E;  2R7Z F;  4C3H F;  2R92 F;  4A3F F;  3S1R F;  1ZYR E;  4YFN E;  3FKI F;  2PMZ K;  5IYB F;  3HOV F;  4BY1 F;  2NVY F;  3S16 F;  4A3I F;  3PO3 F;  5TMF E;  1R9T F;  2NVQ F;  4A3L F;  3S1M F;  4Q5S E;  2JA6 F;  5M3F F;  2BE5 E;  5C3E F;  4A3B F;  4A3D F;  3GTP F;  4A3M F;  4BXX F;  5E18 E;  2E2I F;  4A3K F;  4A3E F;  2A69 E;  3EQL E;  2E2J F;  5M5Y F;  4YFX E;  4Y52 F;  3H0G F;  2WB1 I;  4KN7 E;  2CW0 E;  3M4O F;  2E2H F;  3S14 F;  5BYH E;  4G7H E;  4GZY E;  2NVX F;  5M3M F;  4OIR E;  3HKZ K;  5IP9 F;  1TWA F;  4G7Z E;  4C3I F;  4Y7N F;  5IPL E;  5D4E E;  3HOX F;  2YU9 F;  3GTJ F;  3HOU F;  1K83 F;  1TWC F;  2JA5 F;  1YNN K;  2JA8 F;  3HOZ F;  2Y0S I;  2B63 F;  2NVT F;  1WCM F;  4LJZ E;  4A3G F;  5FLM F;  1I6H F;  5D4D E;  3GTO F;  3S2D F;  3K7A F;  1YNJ K;  4C3J F;  1SFO F;  4G7O E;  1IW7 E;  1TWF F;  3RZO F;  5FJ8 F;  3S15 F;  5E17 E;  4OIP E;  4YFK E;  4KMU E; 
#chains in the Genus database with same CATH topology
 4BY7 F;  5M5X F;  5M5W F;  5C3E E;  2KRX A;  3RZD F;  2NVT E;  4A3B E;  2R93 F;  4A3D E;  5C4X F;  4OIN E;  3GTP E;  4JK1 E;  4LK0 E;  5FLM E;  4A3M E;  4C2M F;  3GTK F;  3H3V G;  1HQM E;  3DXJ E;  4BXX E;  4A3K E;  4A3E E;  2A68 E;  4A3J F;  2E2J E;  3GTM F;  5M5Y E;  3HOY F;  3WOD E;  4OIQ E;  4BBR F;  4XSZ E;  3PO2 F;  4Y52 E;  4AYB K;  3H0G E;  2O5I E;  4LLG E;  3M4O E;  2E2H E;  3S1Q F;  1QKL A;  1Y1W F;  2NVX E;  5IP7 F;  4A3C F;  4AYB H;  5M3M E;  3GTG F;  5IP9 E;  1TWA E;  2PPB E;  4C3I E;  3S17 F;  4Y7N E;  3S2H F;  5M5X E;  4XLN E;  3HOX E;  3GTJ E;  3RZD E;  2YU9 E;  3GTL F;  1K83 E;  1TWC E;  1Y1V F;  3HOU E;  3HOW F;  4BBS F;  4XLP E;  1DZF A;  2JA5 E;  2O5J E;  2JA8 E;  4MEX E;  2JA7 F;  2B63 E;  4LK1 E;  3GTM E;  1WCM E;  4XSX E;  4Q4Z E;  4A3G E;  3S1N F;  1I6H E;  1TWH F;  2A6E E;  2WAQ K;  3I4M F;  4X6A F;  3I4N F;  4ZH4 E;  3GTO E;  3S2D E;  3K7A E;  5IYC F;  1TWG F;  1SFO E;  2A6H E;  2WAQ H;  4MEY E;  1I6V E;  4C3J E;  5D4C E;  5C44 F;  4A93 F;  1SMY E;  1I50 F;  5TMC E;  2VUM F;  4YG2 E;  3M3Y F;  4OIO E;  1TWF E;  4MQ9 E;  5C4J F;  3GTQ F;  3CQZ F;  3RZO E;  5FJ8 E;  3S15 E;  1I3Q F;  5IYD F;  4KN4 E;  2R7Z F;  4C3H F;  3HOZ E;  4BY7 E;  2R92 F;  4A3F F;  3S1R F;  1ZYR E;  4YFN E;  3FKI F;  2PMZ K;  5M5W E;  5IYB F;  3HOV F;  2R93 E;  4BY1 F;  5C4X E;  2NVY F;  3S16 F;  4C2M E;  4A3I F;  5TMF E;  1R9T F;  3GTK E;  2NVQ F;  3PO3 F;  4A3L F;  2PMZ H;  3S1M F;  4A3J E;  4Q5S E;  2JA6 F;  5M3F F;  2BE5 E;  3HOY E;  5M3F E;  5IYC E;  5C3E F;  3H3V F;  2WB1 H;  4A3B F;  4A3D F;  4BBR E;  3GTP F;  3PO2 E;  4A3M F;  4BXX F;  1EIK A;  5E18 E;  2E2I F;  4A3K F;  4A3E F;  2A69 E;  3EQL E;  3M3Y E;  3S1Q E;  1Y1W E;  2E2J F;  3CQZ E;  5IP7 E;  5M5Y F;  4A3C E;  3GTG E;  3S17 E;  4YFX E;  3S2H E;  4C3H E;  4Y52 F;  3H0G F;  2WB1 I;  4KN7 E;  2CW0 E;  4QIW K;  3GTL E;  3HOW E;  2E2H F;  3M4O F;  3S14 F;  1Y1V E;  4BY1 E;  4BBS E;  5BYH E;  4G7H E;  4GZY E;  2Y0S H;  2NVX F;  5M3M F;  4OIR E;  3HKZ K;  5IP9 F;  1TWA F;  4QIW H;  4C3I F;  4G7Z E;  3S1M E;  4Y7N F;  2JA7 E;  5IPL E;  5D4E E;  3HOX F;  2YU9 F;  3GTJ F;  3HOU F;  3HKZ H;  1K83 F;  1TWC F;  3S1N E;  1TWH E;  2JA5 F;  1YNN K;  3I4M E;  2JA8 F;  2E2I E;  3I4N E;  3HOZ F;  4X6A E;  2Y0S I;  2B63 F;  2NVT F;  1WCM F;  1TWG E;  4LJZ E;  4A93 E;  4A3G F;  5C44 E;  5FLM F;  1I6H F;  1I50 E;  2VUM E;  5D4D E;  3GTQ E;  5C4J E;  3GTO F;  3S14 E;  2JA6 E;  3K7A F;  3S2D F;  1I3Q E;  1YNJ K;  5IYD E;  4C3J F;  1SFO F;  2R7Z E;  2R92 E;  4A3F E;  3S1R E;  3FKI E;  3HOV E;  5IYB E;  4G7O E;  1IW7 E;  1TWF F;  2NVY E;  3RZO F;  3S16 E;  4A3I E;  3PO3 E;  5FJ8 F;  1R9T E;  3S15 F;  2NVQ E;  5E17 E;  4A3L E;  4OIP E;  4YFK E;  4KMU E; 
#chains in the Genus database with same CATH homology
 4BY7 F;  5M5X F;  5M5W F;  3RZD F;  2KRX A;  2R93 F;  5C4X F;  4OIN E;  4JK1 E;  4LK0 E;  3H3V G;  4C2M F;  3GTK F;  1HQM E;  3DXJ E;  2A68 E;  4A3J F;  3GTM F;  3HOY F;  3WOD E;  4OIQ E;  4BBR F;  4XSZ E;  3PO2 F;  4AYB K;  2O5I E;  4LLG E;  3S1Q F;  1QKL A;  1Y1W F;  4A3C F;  5IP7 F;  3GTG F;  3S17 F;  2PPB E;  3S2H F;  4XLN E;  3GTL F;  3HOW F;  1Y1V F;  4BBS F;  4XLP E;  2O5J E;  4MEX E;  2JA7 F;  4LK1 E;  4XSX E;  4Q4Z E;  3S1N F;  1TWH F;  2A6E E;  2WAQ K;  3I4M F;  4X6A F;  3I4N F;  4ZH4 E;  5IYC F;  1TWG F;  2A6H E;  5D4C E;  4MEY E;  1I6V E;  4A93 F;  5C44 F;  1SMY E;  1I50 F;  5TMC E;  2VUM F;  4YG2 E;  3M3Y F;  4OIO E;  4MQ9 E;  5C4J F;  3GTQ F;  3CQZ F;  1I3Q F;  5IYD F;  4KN4 E;  2R7Z F;  4C3H F;  2R92 F;  4A3F F;  3S1R F;  1ZYR E;  4YFN E;  3FKI F;  2PMZ K;  5IYB F;  3HOV F;  4BY1 F;  2NVY F;  3S16 F;  4A3I F;  3PO3 F;  5TMF E;  1R9T F;  2NVQ F;  4A3L F;  3S1M F;  4Q5S E;  2JA6 F;  5M3F F;  2BE5 E;  5C3E F;  4A3B F;  4A3D F;  3GTP F;  4A3M F;  4BXX F;  5E18 E;  2E2I F;  4A3K F;  4A3E F;  2A69 E;  3EQL E;  2E2J F;  5M5Y F;  4YFX E;  4Y52 F;  3H0G F;  2WB1 I;  4KN7 E;  2CW0 E;  4QIW K;  3M4O F;  2E2H F;  3S14 F;  5BYH E;  4G7H E;  4GZY E;  2NVX F;  5M3M F;  4OIR E;  3HKZ K;  5IP9 F;  1TWA F;  4G7Z E;  4C3I F;  4Y7N F;  5IPL E;  5D4E E;  3HOX F;  2YU9 F;  3GTJ F;  3HOU F;  1K83 F;  1TWC F;  2JA5 F;  1YNN K;  2JA8 F;  3HOZ F;  2Y0S I;  2B63 F;  2NVT F;  1WCM F;  4LJZ E;  4A3G F;  5FLM F;  1I6H F;  5D4D E;  3GTO F;  3S2D F;  3K7A F;  1YNJ K;  4C3J F;  1SFO F;  4G7O E;  1IW7 E;  1TWF F;  3RZO F;  5FJ8 F;  3S15 F;  5E17 E;  4OIP E;  4YFK E;  4KMU E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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