1TWCF

Rna polymerase ii complexed with gtp
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
83
structure length
83
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 23
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1twcF00
4XLPE 3S14F 2R93F 4LK0E 5IYDF 4KN4E 2E2IF 5C44F 3GTLF 2PMZK 4JK1E 1I6HF 5C4XF 4A3FF 4C2MF 4ZH4E 5IYCF 3S17F 2A68E 5D4DE 3GTMF 3S1MF 2B63F 2PPBE 4YFXE 4X6AF 5E18E 1I6VE 5IP9F 3M3YF 1YNNK 2NVTF 5D4CE 1SMYE 4OIQE 5D4EE 4A3KF 1I50F 3RZOF 1WCMF 5C3EF 3S2DF 2O5IE 1Y1VF 5FLMF 4LLGE 3PO2F 4A3DF 5E17E 5IPLE 1TWFF 3S2HF 4OIRE 4XSXE 2E2HF 4KMUE 4A3JF 1TWHF 4OIPE 3FKIF 2JA7F 4OIOE 1ZYRE 3GTJF 5M5YF 4Y7NF 2JA5F 2JA8F 4A3CF 3HOVF 3HOZF 5M5WF 2WAQK 4G7ZE 4Q5SE 1TWAF 2NVQF 3I4MF 1TWGF 2NVYF 4A3LF 1I3QF 3S1RF 3GTQF 2CW0E 1QKLA 2JA6F 4BY1F 5TMFE 3RZDF 4A3IF 1R9TF 4BXXF 3GTOF 5IP7F 4MEXE 5M3FF 4A3BF 1TWCF 4MQ9E 4C3IF 4MEYE 4XSZE 3HOYF 4YG2E 4KN7E 4A3EF 5M5XF 2O5JE 3I4NF 2BE5E 5BYHE 4G7OE 3S1NF 1K83F 2NVXF 4YFKE 1IW7E 3H3VG 3S15F 4LK1E 4G7HE 4XLNE 2Y0SI 2A69E 3PO3F 3EQLE 3DXJE 1HQME 4YFNE 3S1QF 5IYBF 4BBSF 3GTPF 2R7ZF 4Q4ZE 1SFOF 3HOWF 2A6HE 3WODE 1Y1WF 5C4JF 5TMCE 2A6EE 4A93F 3CQZF 3M4OF 3HOUF 4GZYE 3GTGF 5FJ8F 4BY7F 4AYBK 5M3MF 3HOXF 2VUMF 4A3MF 3S16F 3K7AF 4Y52F 2R92F 3GTKF 3HKZK 4C3JF 2E2JF 3H0GF 4BBRF 1YNJK 4LJZE 4A3GF 4OINE 4C3HF 2YU9F 2WB1I
chains in the Genus database with same CATH superfamily
2KRXA 2VUME 4A3ME 4XLPE 3S14F 2R93F 4LK0E 5IYDF 3S16E 3K7AE 2R92E 3GTKE 4Y52E 4KN4E 2E2IF 4C3JE 5C44F 3GTLF 2PMZK 4JK1E 1I6HF 5C4XF 4A3FF 4C2MF 2E2JE 3H0GE 4ZH4E 4BBRE 5IYCF 3S17F 4A3GE 2A68E 5D4DE 3GTMF 4C3HE 3S1MF 2YU9E 2B63F 2PPBE 4YFXE 3S14E 4X6AF 5E18E 2R93E 1I6VE 5IP9F 5IYDE 3M3YF 1YNNK 2NVTF 5D4CE 1SMYE 2E2IE 5C44E 4OIQE 3GTLE 5C4XE 1I6HE 5D4EE 4C2ME 4A3FE 1I50F 4A3KF 3M4OE 3RZOF 1WCMF 5IYCE 5C3EF 2O5IE 1Y1VF 3S17E 5FLMF 3S2DF 4LLGE 3GTME 3S1ME 3PO2F 4A3DF 2B63E 5E17E 1DZFA 5IPLE 1TWFF 4X6AE 2WB1H 3S2HF 5IP9E 4OIRE 3M3YE 4XSXE 2E2HF 2NVTE 4KMUE 4A3JF 1TWHF 4A3KE 1I50E 4OIPE 4AYBH 3FKIF 2JA7F 3RZOE 4OIOE 1WCME 5C3EE 3S2DE 1Y1VE 1ZYRE 5FLME 3GTJF 5M5YF 3PO2E 4A3DE 4Y7NF 2JA5F 2JA8F 1TWFE 3HKZH 3S2HE 4A3CF 3HOVF 3HOZF 5M5WF 2E2HE 4QIWK 2WAQK 4G7ZE 4Q5SE 1TWAF 2NVQF 1TWHE 3I4MF 1TWGF 2NVYF 3FKIE 1I3QF 3S1RF 2JA7E 3GTQF 4A3LF 2CW0E 1QKLA 2JA6F 4BY1F 5TMFE 3GTJE 4A3IF 3RZDF 1R9TF 3GTOF 5IP7F 4BXXF 5M5YE 4MEXE 4Y7NE 5M3FF 3H3VF 4A3BF 2JA5E 1TWCF 4MQ9E 4C3IF 4MEYE 4XSZE 2JA8E 2PMZH 4YG2E 4KN7E 3HOYF 3HOVE 3HOZE 4A3CE 5M5WE 4A3EF 5M5XF 2O5JE 1TWAE 2NVQE 3I4NF 2BE5E 3I4ME 5BYHE 1TWGE 2NVYE 3S1NF 1I3QE 3S1RE 3GTQE 4A3LE 1K83F 2NVXF 4G7OE 2JA6E 4BY1E 1R9TE 3RZDE 4A3IE 4BXXE 4YFKE 1IW7E 5IP7E 3GTOE 3H3VG 3S15F 4LK1E 5M3FE 4A3BE 1TWCE 4C3IE 4G7HE 4XLNE 3HOYE 2Y0SI 2A69E 3PO3F 3EQLE 3DXJE 1HQME 4YFNE 5M5XE 4A3JE 4A3EE 3I4NE 3S1QF 1EIKA 5IYBF 4BBSF 3GTPF 3S1NE 2R7ZF 1K83E 4Q4ZE 1SFOF 2NVXE 3HOWF 2A6HE 3WODE 1Y1WF 3S15E 5C4JF 5TMCE 2A6EE 4A93F 3CQZF 3M4OF 3HOUF 4GZYE 3PO3E 3GTGF 5FJ8F 3S1QE 4BY7F 4AYBK 5M3MF 3HOXF 5IYBE 2VUMF 4A3MF 4BBSE 3GTPE 2R7ZE 1SFOE 3S16F 3K7AF 3HOWE 4Y52F 2R92F 3GTKF 3HKZK 4C3JF 1Y1WE 5C4JE 4QIWH 2WAQH 4A93E 3CQZE 2E2JF 3HOUE 3H0GF 4BBRF 1YNJK 2Y0SH 4LJZE 5FJ8E 3GTGE 4OINE 4BY7E 5M3ME 4A3GF 4C3HF 3HOXE 2YU9F 2WB1I
chains in the Genus database with same CATH topology
2KRXA 4XLPE 3S14F 2R93F 4LK0E 5IYDF 4KN4E 2E2IF 5C44F 3GTLF 2PMZK 4JK1E 1I6HF 5C4XF 4A3FF 4C2MF 4ZH4E 5IYCF 3S17F 2A68E 5D4DE 3GTMF 3S1MF 2B63F 2PPBE 4YFXE 4X6AF 5E18E 1I6VE 5IP9F 3M3YF 1YNNK 2NVTF 5D4CE 1SMYE 4OIQE 5D4EE 4A3KF 1I50F 3RZOF 1WCMF 5C3EF 3S2DF 2O5IE 1Y1VF 5FLMF 4LLGE 3PO2F 4A3DF 5E17E 5IPLE 1TWFF 3S2HF 4OIRE 4XSXE 2E2HF 4KMUE 4A3JF 1TWHF 4OIPE 3FKIF 2JA7F 4OIOE 1ZYRE 3GTJF 5M5YF 4Y7NF 2JA5F 2JA8F 4A3CF 3HOVF 3HOZF 5M5WF 4QIWK 2WAQK 4G7ZE 4Q5SE 1TWAF 2NVQF 3I4MF 1TWGF 2NVYF 4A3LF 1I3QF 3S1RF 3GTQF 2CW0E 1QKLA 2JA6F 4BY1F 5TMFE 3RZDF 4A3IF 1R9TF 4BXXF 3GTOF 5IP7F 4MEXE 5M3FF 4A3BF 1TWCF 4MQ9E 4C3IF 4MEYE 4XSZE 3HOYF 4YG2E 4KN7E 4A3EF 5M5XF 2O5JE 3I4NF 2BE5E 5BYHE 4G7OE 3S1NF 1K83F 2NVXF 4YFKE 1IW7E 3H3VG 3S15F 4LK1E 4G7HE 4XLNE 2Y0SI 2A69E 3PO3F 3EQLE 3DXJE 1HQME 4YFNE 3S1QF 5IYBF 4BBSF 3GTPF 2R7ZF 4Q4ZE 1SFOF 3HOWF 2A6HE 3WODE 1Y1WF 5C4JF 5TMCE 2A6EE 4A93F 3CQZF 3M4OF 3HOUF 4GZYE 3GTGF 5FJ8F 4BY7F 4AYBK 5M3MF 3HOXF 2VUMF 4A3MF 3S16F 3K7AF 4Y52F 2R92F 3GTKF 3HKZK 4C3JF 2E2JF 3H0GF 4BBRF 1YNJK 4LJZE 4A3GF 4OINE 4C3HF 2YU9F 2WB1I
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XLP E;  3S14 F;  2R93 F;  4LK0 E;  5IYD F;  4KN4 E;  2E2I F;  5C44 F;  3GTL F;  2PMZ K;  4JK1 E;  1I6H F;  5C4X F;  4A3F F;  4C2M F;  4ZH4 E;  5IYC F;  3S17 F;  2A68 E;  5D4D E;  3GTM F;  3S1M F;  2B63 F;  2PPB E;  4YFX E;  4X6A F;  5E18 E;  1I6V E;  5IP9 F;  3M3Y F;  1YNN K;  2NVT F;  5D4C E;  1SMY E;  4OIQ E;  5D4E E;  4A3K F;  1I50 F;  3RZO F;  1WCM F;  5C3E F;  3S2D F;  2O5I E;  1Y1V F;  5FLM F;  4LLG E;  3PO2 F;  4A3D F;  5E17 E;  5IPL E;  1TWF F;  3S2H F;  4OIR E;  4XSX E;  2E2H F;  4KMU E;  4A3J F;  1TWH F;  4OIP E;  3FKI F;  2JA7 F;  4OIO E;  1ZYR E;  3GTJ F;  5M5Y F;  4Y7N F;  2JA5 F;  2JA8 F;  4A3C F;  3HOV F;  3HOZ F;  5M5W F;  2WAQ K;  4G7Z E;  4Q5S E;  1TWA F;  2NVQ F;  3I4M F;  1TWG F;  2NVY F;  4A3L F;  1I3Q F;  3S1R F;  3GTQ F;  2CW0 E;  1QKL A;  2JA6 F;  4BY1 F;  5TMF E;  3RZD F;  4A3I F;  1R9T F;  4BXX F;  3GTO F;  5IP7 F;  4MEX E;  5M3F F;  4A3B F;  1TWC F;  4MQ9 E;  4C3I F;  4MEY E;  4XSZ E;  3HOY F;  4YG2 E;  4KN7 E;  4A3E F;  5M5X F;  2O5J E;  3I4N F;  2BE5 E;  5BYH E;  4G7O E;  3S1N F;  1K83 F;  2NVX F;  4YFK E;  1IW7 E;  3H3V G;  3S15 F;  4LK1 E;  4G7H E;  4XLN E;  2Y0S I;  2A69 E;  3PO3 F;  3EQL E;  3DXJ E;  1HQM E;  4YFN E;  3S1Q F;  5IYB F;  4BBS F;  3GTP F;  2R7Z F;  4Q4Z E;  1SFO F;  3HOW F;  2A6H E;  3WOD E;  1Y1W F;  5C4J F;  5TMC E;  2A6E E;  4A93 F;  3CQZ F;  3M4O F;  3HOU F;  4GZY E;  3GTG F;  5FJ8 F;  4BY7 F;  4AYB K;  5M3M F;  3HOX F;  2VUM F;  4A3M F;  3S16 F;  3K7A F;  4Y52 F;  2R92 F;  3GTK F;  3HKZ K;  4C3J F;  2E2J F;  3H0G F;  4BBR F;  1YNJ K;  4LJZ E;  4A3G F;  4OIN E;  4C3H F;  2YU9 F;  2WB1 I; 
#chains in the Genus database with same CATH topology
 2KRX A;  2VUM E;  4A3M E;  4XLP E;  3S14 F;  2R93 F;  4LK0 E;  5IYD F;  3S16 E;  3K7A E;  2R92 E;  3GTK E;  4Y52 E;  4KN4 E;  2E2I F;  4C3J E;  5C44 F;  3GTL F;  2PMZ K;  4JK1 E;  1I6H F;  5C4X F;  4A3F F;  4C2M F;  2E2J E;  3H0G E;  4ZH4 E;  4BBR E;  5IYC F;  3S17 F;  4A3G E;  2A68 E;  5D4D E;  3GTM F;  4C3H E;  3S1M F;  2YU9 E;  2B63 F;  2PPB E;  4YFX E;  3S14 E;  4X6A F;  5E18 E;  2R93 E;  1I6V E;  5IP9 F;  5IYD E;  3M3Y F;  1YNN K;  2NVT F;  5D4C E;  1SMY E;  2E2I E;  5C44 E;  4OIQ E;  3GTL E;  5C4X E;  1I6H E;  5D4E E;  4C2M E;  4A3F E;  1I50 F;  4A3K F;  3M4O E;  3RZO F;  1WCM F;  5IYC E;  5C3E F;  2O5I E;  1Y1V F;  3S17 E;  5FLM F;  3S2D F;  4LLG E;  3GTM E;  3S1M E;  3PO2 F;  4A3D F;  2B63 E;  5E17 E;  1DZF A;  5IPL E;  1TWF F;  4X6A E;  2WB1 H;  3S2H F;  5IP9 E;  4OIR E;  3M3Y E;  4XSX E;  2E2H F;  2NVT E;  4KMU E;  4A3J F;  1TWH F;  4A3K E;  1I50 E;  4OIP E;  4AYB H;  3FKI F;  2JA7 F;  3RZO E;  4OIO E;  1WCM E;  5C3E E;  3S2D E;  1Y1V E;  1ZYR E;  5FLM E;  3GTJ F;  5M5Y F;  3PO2 E;  4A3D E;  4Y7N F;  2JA5 F;  2JA8 F;  1TWF E;  3HKZ H;  3S2H E;  4A3C F;  3HOV F;  3HOZ F;  5M5W F;  2E2H E;  4QIW K;  2WAQ K;  4G7Z E;  4Q5S E;  1TWA F;  2NVQ F;  1TWH E;  3I4M F;  1TWG F;  2NVY F;  3FKI E;  1I3Q F;  3S1R F;  2JA7 E;  3GTQ F;  4A3L F;  2CW0 E;  1QKL A;  2JA6 F;  4BY1 F;  5TMF E;  3GTJ E;  4A3I F;  3RZD F;  1R9T F;  3GTO F;  5IP7 F;  4BXX F;  5M5Y E;  4MEX E;  4Y7N E;  5M3F F;  3H3V F;  4A3B F;  2JA5 E;  1TWC F;  4MQ9 E;  4C3I F;  4MEY E;  4XSZ E;  2JA8 E;  2PMZ H;  4YG2 E;  4KN7 E;  3HOY F;  3HOV E;  3HOZ E;  4A3C E;  5M5W E;  4A3E F;  5M5X F;  2O5J E;  1TWA E;  2NVQ E;  3I4N F;  2BE5 E;  3I4M E;  5BYH E;  1TWG E;  2NVY E;  3S1N F;  1I3Q E;  3S1R E;  3GTQ E;  4A3L E;  1K83 F;  2NVX F;  4G7O E;  2JA6 E;  4BY1 E;  1R9T E;  3RZD E;  4A3I E;  4BXX E;  4YFK E;  1IW7 E;  5IP7 E;  3GTO E;  3H3V G;  3S15 F;  4LK1 E;  5M3F E;  4A3B E;  1TWC E;  4C3I E;  4G7H E;  4XLN E;  3HOY E;  2Y0S I;  2A69 E;  3PO3 F;  3EQL E;  3DXJ E;  1HQM E;  4YFN E;  5M5X E;  4A3J E;  4A3E E;  3I4N E;  3S1Q F;  1EIK A;  5IYB F;  4BBS F;  3GTP F;  3S1N E;  2R7Z F;  1K83 E;  4Q4Z E;  1SFO F;  2NVX E;  3HOW F;  2A6H E;  3WOD E;  1Y1W F;  3S15 E;  5C4J F;  5TMC E;  2A6E E;  4A93 F;  3CQZ F;  3M4O F;  3HOU F;  4GZY E;  3PO3 E;  3GTG F;  5FJ8 F;  3S1Q E;  4BY7 F;  4AYB K;  5M3M F;  3HOX F;  5IYB E;  2VUM F;  4A3M F;  4BBS E;  3GTP E;  2R7Z E;  1SFO E;  3S16 F;  3K7A F;  3HOW E;  4Y52 F;  2R92 F;  3GTK F;  3HKZ K;  4C3J F;  1Y1W E;  5C4J E;  4QIW H;  2WAQ H;  4A93 E;  3CQZ E;  2E2J F;  3HOU E;  3H0G F;  4BBR F;  1YNJ K;  2Y0S H;  4LJZ E;  5FJ8 E;  3GTG E;  4OIN E;  4BY7 E;  5M3M E;  4A3G F;  4C3H F;  3HOX E;  2YU9 F;  2WB1 I; 
#chains in the Genus database with same CATH homology
 2KRX A;  4XLP E;  3S14 F;  2R93 F;  4LK0 E;  5IYD F;  4KN4 E;  2E2I F;  5C44 F;  3GTL F;  2PMZ K;  4JK1 E;  1I6H F;  5C4X F;  4A3F F;  4C2M F;  4ZH4 E;  5IYC F;  3S17 F;  2A68 E;  5D4D E;  3GTM F;  3S1M F;  2B63 F;  2PPB E;  4YFX E;  4X6A F;  5E18 E;  1I6V E;  5IP9 F;  3M3Y F;  1YNN K;  2NVT F;  5D4C E;  1SMY E;  4OIQ E;  5D4E E;  4A3K F;  1I50 F;  3RZO F;  1WCM F;  5C3E F;  3S2D F;  2O5I E;  1Y1V F;  5FLM F;  4LLG E;  3PO2 F;  4A3D F;  5E17 E;  5IPL E;  1TWF F;  3S2H F;  4OIR E;  4XSX E;  2E2H F;  4KMU E;  4A3J F;  1TWH F;  4OIP E;  3FKI F;  2JA7 F;  4OIO E;  1ZYR E;  3GTJ F;  5M5Y F;  4Y7N F;  2JA5 F;  2JA8 F;  4A3C F;  3HOV F;  3HOZ F;  5M5W F;  4QIW K;  2WAQ K;  4G7Z E;  4Q5S E;  1TWA F;  2NVQ F;  3I4M F;  1TWG F;  2NVY F;  4A3L F;  1I3Q F;  3S1R F;  3GTQ F;  2CW0 E;  1QKL A;  2JA6 F;  4BY1 F;  5TMF E;  3RZD F;  4A3I F;  1R9T F;  4BXX F;  3GTO F;  5IP7 F;  4MEX E;  5M3F F;  4A3B F;  1TWC F;  4MQ9 E;  4C3I F;  4MEY E;  4XSZ E;  3HOY F;  4YG2 E;  4KN7 E;  4A3E F;  5M5X F;  2O5J E;  3I4N F;  2BE5 E;  5BYH E;  4G7O E;  3S1N F;  1K83 F;  2NVX F;  4YFK E;  1IW7 E;  3H3V G;  3S15 F;  4LK1 E;  4G7H E;  4XLN E;  2Y0S I;  2A69 E;  3PO3 F;  3EQL E;  3DXJ E;  1HQM E;  4YFN E;  3S1Q F;  5IYB F;  4BBS F;  3GTP F;  2R7Z F;  4Q4Z E;  1SFO F;  3HOW F;  2A6H E;  3WOD E;  1Y1W F;  5C4J F;  5TMC E;  2A6E E;  4A93 F;  3CQZ F;  3M4O F;  3HOU F;  4GZY E;  3GTG F;  5FJ8 F;  4BY7 F;  4AYB K;  5M3M F;  3HOX F;  2VUM F;  4A3M F;  3S16 F;  3K7A F;  4Y52 F;  2R92 F;  3GTK F;  3HKZ K;  4C3J F;  2E2J F;  3H0G F;  4BBR F;  1YNJ K;  4LJZ E;  4A3G F;  4OIN E;  4C3H F;  2YU9 F;  2WB1 I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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