1TWHF

Rna polymerase ii complexed with 2'datp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
83
structure length
83
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 21
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1twhF00
3M4OF 3S17F 3GTOF 2BE5E 5BYHE 2CW0E 2E2HF 2B63F 2JA5F 5IYBF 4A3GF 4X6AF 1TWFF 2WAQK 3RZDF 3S2DF 1ZYRE 3I4MF 2Y0SI 4Q5SE 1QKLA 4C2MF 5FLMF 4OIQE 2PPBE 4G7HE 4YFXE 3GTPF 4G7ZE 4A3LF 1SMYE 4C3JF 1I6HF 1SFOF 4BY1F 5C3EF 4A3JF 2A69E 4GZYE 1I6VE 2JA8F 3PO3F 4XSXE 3K7AF 4A3KF 3GTQF 4Y7NF 4C3IF 4KN4E 5E18E 4KN7E 4YG2E 3RZOF 3HKZK 4A3CF 4OIRE 5TMCE 4MEYE 4C3HF 5M5WF 2NVTF 2VUMF 1Y1WF 4MEXE 3S14F 5C44F 2NVXF 4ZH4E 2R92F 3EQLE 3S1QF 2JA7F 2R93F 3WODE 3S15F 2NVYF 2A6HE 1I3QF 3S1MF 5E17E 3S2HF 5IYDF 3HOXF 4G7OE 4A3MF 4XSZE 4A3FF 2JA6F 3GTJF 2WB1I 4LJZE 4XLNE 4LK0E 4YFNE 1TWHF 5M3MF 1YNJK 4OIPE 2E2IF 3PO2F 3GTKF 1TWGF 3HOUF 4Q4ZE 3S1NF 5FJ8F 1YNNK 4MQ9E 1HQME 3FKIF 4A3BF 5IP9F 2NVQF 1TWCF 3DXJE 5M5YF 5C4XF 3HOVF 5D4DE 1WCMF 4A93F 3HOYF 4LLGE 3M3YF 4A3EF 4OINE 2A68E 5D4EE 3GTLF 2YU9F 5M3FF 5C4JF 3S1RF 3I4NF 2R7ZF 3GTGF 4OIOE 3HOZF 3H0GF 5IYCF 2O5IE 1IW7E 2A6EE 2O5JE 4KMUE 4BBRF 3CQZF 1Y1VF 5D4CE 4BXXF 4YFKE 4JK1E 1K83F 5IPLE 3S16F 4A3IF 2PMZK 4BBSF 5TMFE 3GTMF 4LK1E 5M5XF 4Y52F 3H3VG 5IP7F 1R9TF 1TWAF 4AYBK 4BY7F 1I50F 4XLPE 4A3DF 2E2JF 3HOWF
chains in the Genus database with same CATH superfamily
5IYDE 3M4OF 4C3JE 1I6HE 3S17F 1SFOE 2KRXA 4BY1E 4A3JE 3GTOF 2BE5E 2WAQH 5BYHE 2CW0E 2E2HF 2B63F 2JA8E 3PO3E 2E2IE 3K7AE 4A3KE 2JA5F 4Y7NE 4C3IE 5IYBF 3GTQE 4A3GF 4X6AF 1TWFF 2WAQK 4A3CE 3RZDF 4C3HE 5M5WE 2NVTE 1ZYRE 3S2DF 2VUME 3I4MF 2Y0SI 1Y1WE 4Q5SE 1QKLA 3S14E 4C2MF 5FLMF 4OIQE 5C44E 2PPBE 3HOVE 4G7HE 4YFXE 1WCME 2R92E 3GTPF 4G7ZE 3S1QE 2JA7E 4A3LF 2R93E 1SMYE 4C3JF 3S15E 4A3EE 1I6HF 2NVYE 4BY1F 1SFOF 1I3QE 3S1ME 5C3EF 5C4JE 3S2HE 4A3JF 2A69E 3HOXE 3H3VF 3GTPE 1I6VE 4GZYE 4A3ME 2JA8F 4XSXE 3PO3F 3K7AF 4A3FE 4A3KF 4Y7NF 4C3IF 4KN4E 3GTJE 2JA6E 5E18E 4KN7E 4YG2E 3RZOF 3HKZK 4A3CF 4OIRE 5TMCE 4MEYE 1DZFA 1TWHE 4C3HF 5M3ME 5M5WF 2NVTF 3PO2E 2VUMF 3GTKE 1TWGE 3HOUE 4QIWH 1Y1WF 3S1NE 4MEXE 3S14F 5FJ8E 5C44F 3FKIE 4A3BE 1K83E 5IP9E 2NVQE 2NVXF 1TWCE 4ZH4E 2R92F 4QIWK 3EQLE 5M5YE 3S16E 3S1QF 2JA7F 5C4XE 2R93F 3WODE 3S15F 2NVYF 2A6HE 1I3QF 3S1MF 4A93E 3HOYE 3S2HF 5E17E 5IYDF 3M3YE 3HOXF 4G7OE 4A3MF 3GTLE 2YU9E 5M3FE 4XSZE 4A3FF 3S1RE 2JA6F 3GTJF 2R7ZE 3GTGE 2WB1I 4LJZE 4XLNE 3HOWE 3I4NE 3HOZE 3GTQF 2Y0SH 3HKZH 3H0GE 4LK0E 4YFNE 1TWHF 1YNJK 5IYCE 4OIPE 5M3MF 2E2IF 3PO2F 3GTKF 1TWGF 3HOUF 4Q4ZE 3S1NF 5FJ8F 1YNNK 4BBRE 4MQ9E 1HQME 3CQZE 3FKIF 4A3BF 5IP9F 1Y1VE 2NVQF 1TWCF 3DXJE 4BXXE 5M5YF 5C4XF 3HOVF 5D4DE 1WCMF 4A93F 3HOYF 4LLGE 4A3IE 4BBSE 3M3YF 4A3EF 4OINE 2A68E 5D4EE 3GTME 3GTLF 2YU9F 5M3FF 5C4JF 5M5XE 3S1RF 3I4NF 3GTGF 2R7ZF 4Y52E 5IP7E 4OIOE 1R9TE 3HOZF 1TWAE 4BY7E 3H0GF 1I50E 5C3EE 5IYCF 4A3DE 2O5IE 2E2JE 1IW7E 2A6EE 3M4OE 2O5JE 4KMUE 4BBRF 3S17E 3CQZF 1Y1VF 5D4CE 4BXXF 4YFKE 3RZOE 3GTOE 2PMZH 2E2HE 2B63E 4JK1E 1K83F 2JA5E 5IYBE 4A3GE 4X6AE 5IPLE 3S16F 4A3IF 1TWFE 2PMZK 3RZDE 4BBSF 4AYBH 2WB1H 3S2DE 2NVXE 5TMFE 3GTMF 4LK1E 3I4ME 5M5XF 4Y52F 4C2ME 5IP7F 5FLME 1R9TF 3H3VG 1TWAF 4AYBK 4BY7F 1I50F 4XLPE 4A3DF 1EIKA 2E2JF 4A3LE 3HOWF
chains in the Genus database with same CATH topology
3M4OF 3S17F 2KRXA 3GTOF 2BE5E 5BYHE 2CW0E 2E2HF 2B63F 2JA5F 5IYBF 4A3GF 4X6AF 1TWFF 2WAQK 3RZDF 3S2DF 1ZYRE 3I4MF 2Y0SI 4Q5SE 1QKLA 4C2MF 5FLMF 4OIQE 2PPBE 4G7HE 4YFXE 3GTPF 4G7ZE 4A3LF 1SMYE 4C3JF 1I6HF 1SFOF 4BY1F 5C3EF 4A3JF 2A69E 4GZYE 1I6VE 2JA8F 3PO3F 4XSXE 3K7AF 4A3KF 3GTQF 4Y7NF 4C3IF 4KN4E 5E18E 4KN7E 4YG2E 3RZOF 3HKZK 4A3CF 4OIRE 5TMCE 4MEYE 4C3HF 5M5WF 2NVTF 2VUMF 1Y1WF 4MEXE 3S14F 5C44F 2NVXF 4ZH4E 2R92F 4QIWK 3EQLE 3S1QF 2JA7F 2R93F 3WODE 3S15F 2NVYF 2A6HE 1I3QF 3S1MF 5E17E 3S2HF 5IYDF 3HOXF 4G7OE 4A3MF 4XSZE 4A3FF 2JA6F 3GTJF 2WB1I 4LJZE 4XLNE 4LK0E 4YFNE 1TWHF 5M3MF 1YNJK 4OIPE 2E2IF 3PO2F 3GTKF 1TWGF 3HOUF 4Q4ZE 3S1NF 5FJ8F 1YNNK 4MQ9E 1HQME 3FKIF 4A3BF 5IP9F 2NVQF 1TWCF 3DXJE 5M5YF 5C4XF 3HOVF 5D4DE 1WCMF 4A93F 3HOYF 4LLGE 3M3YF 4A3EF 4OINE 2A68E 5D4EE 3GTLF 2YU9F 5M3FF 5C4JF 3S1RF 3I4NF 2R7ZF 3GTGF 4OIOE 3HOZF 3H0GF 5IYCF 2O5IE 1IW7E 2A6EE 2O5JE 4KMUE 4BBRF 3CQZF 1Y1VF 5D4CE 4BXXF 4YFKE 4JK1E 1K83F 5IPLE 3S16F 4A3IF 2PMZK 4BBSF 5TMFE 3GTMF 4LK1E 5M5XF 4Y52F 3H3VG 5IP7F 1R9TF 1TWAF 4AYBK 4BY7F 1I50F 4XLPE 4A3DF 2E2JF 3HOWF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M4O F;  3S17 F;  3GTO F;  2BE5 E;  5BYH E;  2CW0 E;  2E2H F;  2B63 F;  2JA5 F;  5IYB F;  4A3G F;  4X6A F;  1TWF F;  2WAQ K;  3RZD F;  3S2D F;  1ZYR E;  3I4M F;  2Y0S I;  4Q5S E;  1QKL A;  4C2M F;  5FLM F;  4OIQ E;  2PPB E;  4G7H E;  4YFX E;  3GTP F;  4G7Z E;  4A3L F;  1SMY E;  4C3J F;  1I6H F;  1SFO F;  4BY1 F;  5C3E F;  4A3J F;  2A69 E;  4GZY E;  1I6V E;  2JA8 F;  3PO3 F;  4XSX E;  3K7A F;  4A3K F;  3GTQ F;  4Y7N F;  4C3I F;  4KN4 E;  5E18 E;  4KN7 E;  4YG2 E;  3RZO F;  3HKZ K;  4A3C F;  4OIR E;  5TMC E;  4MEY E;  4C3H F;  5M5W F;  2NVT F;  2VUM F;  1Y1W F;  4MEX E;  3S14 F;  5C44 F;  2NVX F;  4ZH4 E;  2R92 F;  3EQL E;  3S1Q F;  2JA7 F;  2R93 F;  3WOD E;  3S15 F;  2NVY F;  2A6H E;  1I3Q F;  3S1M F;  5E17 E;  3S2H F;  5IYD F;  3HOX F;  4G7O E;  4A3M F;  4XSZ E;  4A3F F;  2JA6 F;  3GTJ F;  2WB1 I;  4LJZ E;  4XLN E;  4LK0 E;  4YFN E;  1TWH F;  5M3M F;  1YNJ K;  4OIP E;  2E2I F;  3PO2 F;  3GTK F;  1TWG F;  3HOU F;  4Q4Z E;  3S1N F;  5FJ8 F;  1YNN K;  4MQ9 E;  1HQM E;  3FKI F;  4A3B F;  5IP9 F;  2NVQ F;  1TWC F;  3DXJ E;  5M5Y F;  5C4X F;  3HOV F;  5D4D E;  1WCM F;  4A93 F;  3HOY F;  4LLG E;  3M3Y F;  4A3E F;  4OIN E;  2A68 E;  5D4E E;  3GTL F;  2YU9 F;  5M3F F;  5C4J F;  3S1R F;  3I4N F;  2R7Z F;  3GTG F;  4OIO E;  3HOZ F;  3H0G F;  5IYC F;  2O5I E;  1IW7 E;  2A6E E;  2O5J E;  4KMU E;  4BBR F;  3CQZ F;  1Y1V F;  5D4C E;  4BXX F;  4YFK E;  4JK1 E;  1K83 F;  5IPL E;  3S16 F;  4A3I F;  2PMZ K;  4BBS F;  5TMF E;  3GTM F;  4LK1 E;  5M5X F;  4Y52 F;  3H3V G;  5IP7 F;  1R9T F;  1TWA F;  4AYB K;  4BY7 F;  1I50 F;  4XLP E;  4A3D F;  2E2J F;  3HOW F; 
#chains in the Genus database with same CATH topology
 5IYD E;  3M4O F;  4C3J E;  1I6H E;  3S17 F;  1SFO E;  2KRX A;  4BY1 E;  4A3J E;  3GTO F;  2BE5 E;  2WAQ H;  5BYH E;  2CW0 E;  2E2H F;  2B63 F;  2JA8 E;  3PO3 E;  2E2I E;  3K7A E;  4A3K E;  2JA5 F;  4Y7N E;  4C3I E;  5IYB F;  3GTQ E;  4A3G F;  4X6A F;  1TWF F;  2WAQ K;  4A3C E;  3RZD F;  4C3H E;  5M5W E;  2NVT E;  1ZYR E;  3S2D F;  2VUM E;  3I4M F;  2Y0S I;  1Y1W E;  4Q5S E;  1QKL A;  3S14 E;  4C2M F;  5FLM F;  4OIQ E;  5C44 E;  2PPB E;  3HOV E;  4G7H E;  4YFX E;  1WCM E;  2R92 E;  3GTP F;  4G7Z E;  3S1Q E;  2JA7 E;  4A3L F;  2R93 E;  1SMY E;  4C3J F;  3S15 E;  4A3E E;  1I6H F;  2NVY E;  4BY1 F;  1SFO F;  1I3Q E;  3S1M E;  5C3E F;  5C4J E;  3S2H E;  4A3J F;  2A69 E;  3HOX E;  3H3V F;  3GTP E;  1I6V E;  4GZY E;  4A3M E;  2JA8 F;  4XSX E;  3PO3 F;  3K7A F;  4A3F E;  4A3K F;  4Y7N F;  4C3I F;  4KN4 E;  3GTJ E;  2JA6 E;  5E18 E;  4KN7 E;  4YG2 E;  3RZO F;  3HKZ K;  4A3C F;  4OIR E;  5TMC E;  4MEY E;  1DZF A;  1TWH E;  4C3H F;  5M3M E;  5M5W F;  2NVT F;  3PO2 E;  2VUM F;  3GTK E;  1TWG E;  3HOU E;  4QIW H;  1Y1W F;  3S1N E;  4MEX E;  3S14 F;  5FJ8 E;  5C44 F;  3FKI E;  4A3B E;  1K83 E;  5IP9 E;  2NVQ E;  2NVX F;  1TWC E;  4ZH4 E;  2R92 F;  4QIW K;  3EQL E;  5M5Y E;  3S16 E;  3S1Q F;  2JA7 F;  5C4X E;  2R93 F;  3WOD E;  3S15 F;  2NVY F;  2A6H E;  1I3Q F;  3S1M F;  4A93 E;  3HOY E;  3S2H F;  5E17 E;  5IYD F;  3M3Y E;  3HOX F;  4G7O E;  4A3M F;  3GTL E;  2YU9 E;  5M3F E;  4XSZ E;  4A3F F;  3S1R E;  2JA6 F;  3GTJ F;  2R7Z E;  3GTG E;  2WB1 I;  4LJZ E;  4XLN E;  3HOW E;  3I4N E;  3HOZ E;  3GTQ F;  2Y0S H;  3HKZ H;  3H0G E;  4LK0 E;  4YFN E;  1TWH F;  1YNJ K;  5IYC E;  4OIP E;  5M3M F;  2E2I F;  3PO2 F;  3GTK F;  1TWG F;  3HOU F;  4Q4Z E;  3S1N F;  5FJ8 F;  1YNN K;  4BBR E;  4MQ9 E;  1HQM E;  3CQZ E;  3FKI F;  4A3B F;  5IP9 F;  1Y1V E;  2NVQ F;  1TWC F;  3DXJ E;  4BXX E;  5M5Y F;  5C4X F;  3HOV F;  5D4D E;  1WCM F;  4A93 F;  3HOY F;  4LLG E;  4A3I E;  4BBS E;  3M3Y F;  4A3E F;  4OIN E;  2A68 E;  5D4E E;  3GTM E;  3GTL F;  2YU9 F;  5M3F F;  5C4J F;  5M5X E;  3S1R F;  3I4N F;  3GTG F;  2R7Z F;  4Y52 E;  5IP7 E;  4OIO E;  1R9T E;  3HOZ F;  1TWA E;  4BY7 E;  3H0G F;  1I50 E;  5C3E E;  5IYC F;  4A3D E;  2O5I E;  2E2J E;  1IW7 E;  2A6E E;  3M4O E;  2O5J E;  4KMU E;  4BBR F;  3S17 E;  3CQZ F;  1Y1V F;  5D4C E;  4BXX F;  4YFK E;  3RZO E;  3GTO E;  2PMZ H;  2E2H E;  2B63 E;  4JK1 E;  1K83 F;  2JA5 E;  5IYB E;  4A3G E;  4X6A E;  5IPL E;  3S16 F;  4A3I F;  1TWF E;  2PMZ K;  3RZD E;  4BBS F;  4AYB H;  2WB1 H;  3S2D E;  2NVX E;  5TMF E;  3GTM F;  4LK1 E;  3I4M E;  5M5X F;  4Y52 F;  4C2M E;  5IP7 F;  5FLM E;  1R9T F;  3H3V G;  1TWA F;  4AYB K;  4BY7 F;  1I50 F;  4XLP E;  4A3D F;  1EIK A;  2E2J F;  4A3L E;  3HOW F; 
#chains in the Genus database with same CATH homology
 3M4O F;  3S17 F;  2KRX A;  3GTO F;  2BE5 E;  5BYH E;  2CW0 E;  2E2H F;  2B63 F;  2JA5 F;  5IYB F;  4A3G F;  4X6A F;  1TWF F;  2WAQ K;  3RZD F;  3S2D F;  1ZYR E;  3I4M F;  2Y0S I;  4Q5S E;  1QKL A;  4C2M F;  5FLM F;  4OIQ E;  2PPB E;  4G7H E;  4YFX E;  3GTP F;  4G7Z E;  4A3L F;  1SMY E;  4C3J F;  1I6H F;  1SFO F;  4BY1 F;  5C3E F;  4A3J F;  2A69 E;  4GZY E;  1I6V E;  2JA8 F;  3PO3 F;  4XSX E;  3K7A F;  4A3K F;  3GTQ F;  4Y7N F;  4C3I F;  4KN4 E;  5E18 E;  4KN7 E;  4YG2 E;  3RZO F;  3HKZ K;  4A3C F;  4OIR E;  5TMC E;  4MEY E;  4C3H F;  5M5W F;  2NVT F;  2VUM F;  1Y1W F;  4MEX E;  3S14 F;  5C44 F;  2NVX F;  4ZH4 E;  2R92 F;  4QIW K;  3EQL E;  3S1Q F;  2JA7 F;  2R93 F;  3WOD E;  3S15 F;  2NVY F;  2A6H E;  1I3Q F;  3S1M F;  5E17 E;  3S2H F;  5IYD F;  3HOX F;  4G7O E;  4A3M F;  4XSZ E;  4A3F F;  2JA6 F;  3GTJ F;  2WB1 I;  4LJZ E;  4XLN E;  4LK0 E;  4YFN E;  1TWH F;  5M3M F;  1YNJ K;  4OIP E;  2E2I F;  3PO2 F;  3GTK F;  1TWG F;  3HOU F;  4Q4Z E;  3S1N F;  5FJ8 F;  1YNN K;  4MQ9 E;  1HQM E;  3FKI F;  4A3B F;  5IP9 F;  2NVQ F;  1TWC F;  3DXJ E;  5M5Y F;  5C4X F;  3HOV F;  5D4D E;  1WCM F;  4A93 F;  3HOY F;  4LLG E;  3M3Y F;  4A3E F;  4OIN E;  2A68 E;  5D4E E;  3GTL F;  2YU9 F;  5M3F F;  5C4J F;  3S1R F;  3I4N F;  2R7Z F;  3GTG F;  4OIO E;  3HOZ F;  3H0G F;  5IYC F;  2O5I E;  1IW7 E;  2A6E E;  2O5J E;  4KMU E;  4BBR F;  3CQZ F;  1Y1V F;  5D4C E;  4BXX F;  4YFK E;  4JK1 E;  1K83 F;  5IPL E;  3S16 F;  4A3I F;  2PMZ K;  4BBS F;  5TMF E;  3GTM F;  4LK1 E;  5M5X F;  4Y52 F;  3H3V G;  5IP7 F;  1R9T F;  1TWA F;  4AYB K;  4BY7 F;  1I50 F;  4XLP E;  4A3D F;  2E2J F;  3HOW F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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