1X6AA

Solution structures of the second lim domain of human lim-kinase 2 (limk2)
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
81
structure length
81
Chain Sequence
GSSGSSGKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVSGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2)
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords LIM domain kinase 2
total genus 6
structure length 81
sequence length 81
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2005-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 1x6aA01
2CUPA 2KBXB 2L6YB 1A7IA 2L6ZC 2JTNA 2O13A 2DARA 2EHEA 2LXDA 2XJYA 1IMLA 1X63A 2XQNT 1WYHA 1X4LA 2MBVA 4HI9B 1X64A 2XJZA 2CU8A 1B8TA 1CXXA 1J2OA 2D8YA 1X61A 1M3VA 1QLIA 2DJ7A 2EGQA 2O10A 2D8XA 4HI8B 1IBIA 1NYPA 1G47A 1X68A 2CUQA 2CURA 4KFZA 2D8ZA 2IYBE 1U5SB 3IXEB 1RUTX 1V6GA 1X6AA 1X62A 2L4ZA 1CTLA 2MIUA 2CO8A 1X3HA 2DLOA 2LZUA 1WIGA 3MMKA 2CORA 2YPAC 4JCJA 3F6QB 2DFYC
chains in the Genus database with same CATH superfamily
2KBXB 5FXVA 2JTNA 2O13A 2LXDA 2XJYA 2XQNT 2MBVA 4BHWA 3NIJA 2CU8A 2DJ7A 2EGQA 1X68A 2D8ZA 2CO8A 1WIGA 5LKZA 2YPAC 2CUPA 2L6YB 5FXZA 2L6ZC 2EHEA 3NILA 3NISA 4HI9B 1X64A 1B8TA 1X61A 4UF0A 4HI8B 2O10A 3ZLIA 1IBIA 1NYPA 3AVRA 4UF0B 1G47A 2CUQA 4KFZA 2IYBE 3IXEB 1RUTX 1X62A 2MIUA 5FXWA 3MMKA 5FYMA 5FY1A 1X63A 4EYUA 1X4LA 5FXXA 3NIHA 5LKUA 1J2OA 5FY7A 2D8YA 1M3VA 2D8XA 2CURA 2XUEA 5FY0A 4EZ4A 3AVSA 1CTLA 5A1LA 2DLOA 5LKXA 2LZUA 3NINA 4JCJA 2XJZA 2DFYC 1A7IA 2DARA 1IMLA 1WYHA 1CXXA 3NIKA 4EZHA 1QLIA 5LKTA 1U5SB 1V6GA 3ZPOA 1X6AA 2L4ZA 1X3HA 5FP3A 2CORA 3NIMA 3F6QB 4ASKA
chains in the Genus database with same CATH topology
2KBXB 5FXVA 2JTNA 2O13A 2LXDA 2XJYA 2XQNT 2MBVA 4BHWA 3NIJA 2CU8A 2DJ7A 2EGQA 1X68A 2D8ZA 2CO8A 1WIGA 5LKZA 2YPAC 2CUPA 2L6YB 5FXZA 2L6ZC 2EHEA 3NILA 3NISA 4HI9B 1X64A 1B8TA 1X61A 4UF0A 4HI8B 2O10A 3ZLIA 1IBIA 1NYPA 3AVRA 4UF0B 1G47A 2CUQA 4KFZA 2IYBE 3IXEB 1RUTX 1X62A 2MIUA 5FXWA 3MMKA 5FYMA 5FY1A 1X63A 4EYUA 1X4LA 5FXXA 3NIHA 5LKUA 1J2OA 5FY7A 2D8YA 1M3VA 2D8XA 2CURA 2XUEA 5FY0A 4EZ4A 3AVSA 1CTLA 5A1LA 2DLOA 5LKXA 2LZUA 3NINA 4JCJA 2XJZA 2DFYC 1A7IA 2DARA 1IMLA 1WYHA 1CXXA 3NIKA 4EZHA 1QLIA 5LKTA 1U5SB 1V6GA 3ZPOA 1X6AA 2L4ZA 1X3HA 5FP3A 2CORA 3NIMA 3F6QB 4ASKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CUP A;  2KBX B;  2L6Y B;  1A7I A;  2L6Z C;  2JTN A;  2O13 A;  2DAR A;  2EHE A;  2LXD A;  2XJY A;  1IML A;  1X63 A;  2XQN T;  1WYH A;  1X4L A;  2MBV A;  4HI9 B;  1X64 A;  2XJZ A;  2CU8 A;  1B8T A;  1CXX A;  1J2O A;  2D8Y A;  1X61 A;  1M3V A;  1QLI A;  2DJ7 A;  2EGQ A;  2O10 A;  2D8X A;  4HI8 B;  1IBI A;  1NYP A;  1G47 A;  1X68 A;  2CUQ A;  2CUR A;  4KFZ A;  2D8Z A;  2IYB E;  1U5S B;  3IXE B;  1RUT X;  1V6G A;  1X6A A;  1X62 A;  2L4Z A;  1CTL A;  2MIU A;  2CO8 A;  1X3H A;  2DLO A;  2LZU A;  1WIG A;  3MMK A;  2COR A;  2YPA C;  4JCJ A;  3F6Q B;  2DFY C; 
#chains in the Genus database with same CATH topology
 2KBX B;  5FXV A;  2JTN A;  2O13 A;  2LXD A;  2XJY A;  2XQN T;  2MBV A;  4BHW A;  3NIJ A;  2CU8 A;  2DJ7 A;  2EGQ A;  1X68 A;  2D8Z A;  2CO8 A;  1WIG A;  5LKZ A;  2YPA C;  2CUP A;  2L6Y B;  5FXZ A;  2L6Z C;  2EHE A;  3NIL A;  3NIS A;  4HI9 B;  1X64 A;  1B8T A;  1X61 A;  4UF0 A;  4HI8 B;  2O10 A;  3ZLI A;  1IBI A;  1NYP A;  3AVR A;  4UF0 B;  1G47 A;  2CUQ A;  4KFZ A;  2IYB E;  3IXE B;  1RUT X;  1X62 A;  2MIU A;  5FXW A;  3MMK A;  5FYM A;  5FY1 A;  1X63 A;  4EYU A;  1X4L A;  5FXX A;  3NIH A;  5LKU A;  1J2O A;  5FY7 A;  2D8Y A;  1M3V A;  2D8X A;  2CUR A;  2XUE A;  5FY0 A;  4EZ4 A;  3AVS A;  1CTL A;  5A1L A;  2DLO A;  5LKX A;  2LZU A;  3NIN A;  4JCJ A;  2XJZ A;  2DFY C;  1A7I A;  2DAR A;  1IML A;  1WYH A;  1CXX A;  3NIK A;  4EZH A;  1QLI A;  5LKT A;  1U5S B;  1V6G A;  3ZPO A;  1X6A A;  2L4Z A;  1X3H A;  5FP3 A;  2COR A;  3NIM A;  3F6Q B;  4ASK A; 
#chains in the Genus database with same CATH homology
 2KBX B;  5FXV A;  2JTN A;  2O13 A;  2LXD A;  2XJY A;  2XQN T;  2MBV A;  4BHW A;  3NIJ A;  2CU8 A;  2DJ7 A;  2EGQ A;  1X68 A;  2D8Z A;  2CO8 A;  1WIG A;  5LKZ A;  2YPA C;  2CUP A;  2L6Y B;  5FXZ A;  2L6Z C;  2EHE A;  3NIL A;  3NIS A;  4HI9 B;  1X64 A;  1B8T A;  1X61 A;  4UF0 A;  4HI8 B;  2O10 A;  3ZLI A;  1IBI A;  1NYP A;  3AVR A;  4UF0 B;  1G47 A;  2CUQ A;  4KFZ A;  2IYB E;  3IXE B;  1RUT X;  1X62 A;  2MIU A;  5FXW A;  3MMK A;  5FYM A;  5FY1 A;  1X63 A;  4EYU A;  1X4L A;  5FXX A;  3NIH A;  5LKU A;  1J2O A;  5FY7 A;  2D8Y A;  1M3V A;  2D8X A;  2CUR A;  2XUE A;  5FY0 A;  4EZ4 A;  3AVS A;  1CTL A;  5A1L A;  2DLO A;  5LKX A;  2LZU A;  3NIN A;  4JCJ A;  2XJZ A;  2DFY C;  1A7I A;  2DAR A;  1IML A;  1WYH A;  1CXX A;  3NIK A;  4EZH A;  1QLI A;  5LKT A;  1U5S B;  1V6G A;  3ZPO A;  1X6A A;  2L4Z A;  1X3H A;  5FP3 A;  2COR A;  3NIM A;  3F6Q B;  4ASK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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