1X6AA

Solution structures of the second lim domain of human lim-kinase 2 (limk2)
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
81
structure length
81
Chain Sequence
GSSGSSGKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVSGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2)
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords LIM domain kinase 2
total genus 6
structure length 81
sequence length 81
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2005-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 1x6aA01
2CUPA 2DFYC 1X61A 4KFZA 2CORA 1WIGA 1V6GA 3MMKA 2EGQA 2D8ZA 4HI8B 1G47A 2LZUA 2XQNT 1IBIA 2L6YB 4JCJA 1X6AA 1NYPA 2DARA 2MIUA 1X4LA 2O13A 1X3HA 1X64A 1A7IA 1J2OA 1WYHA 1M3VA 1U5SB 1X62A 1CTLA 2IYBE 2JTNA 2D8XA 1IMLA 3F6QB 2YPAC 2L4ZA 2CU8A 2CO8A 2CUQA 1CXXA 1X68A 2D8YA 2DJ7A 2KBXB 2MBVA 3IXEB 1RUTX 2O10A 2CURA 2XJZA 4HI9B 2DLOA 2LXDA 1QLIA 1B8TA 1X63A 2L6ZC 2EHEA 2XJYA
chains in the Genus database with same CATH superfamily
2DFYC 4UF0B 3MMKA 2EGQA 4HI8B 2LZUA 2L6YB 4JCJA 1X6AA 4BHWA 2DARA 2O13A 4EYUA 1X3HA 4EZHA 1X64A 3NIMA 2JTNA 5LKXA 5FYMA 5FY7A 2KBXB 1RUTX 2XJZA 5FXXA 1B8TA 3NIKA 4KFZA 3NIJA 1V6GA 3AVSA 1G47A 2MIUA 1X4LA 3ZPOA 5A1LA 1WYHA 1U5SB 5FXVA 2CO8A 1CXXA 2XUEA 2DJ7A 2MBVA 3NISA 4EZ4A 2L4ZA 5FXWA 2L6ZC 2EHEA 2CUPA 5LKTA 2CORA 1WIGA 1IBIA 1M3VA 1X62A 1CTLA 3F6QB 2YPAC 2CUQA 3IXEB 2CURA 3NILA 2DLOA 5FY1A 1QLIA 1X63A 1X61A 3NINA 4UF0A 2D8ZA 2XQNT 1NYPA 5FY0A 5LKZA 3AVRA 5LKUA 3NIHA 5FP3A 1A7IA 1J2OA 3ZLIA 2IYBE 1IMLA 2D8XA 5FXZA 2CU8A 1X68A 2D8YA 4ASKA 2O10A 4HI9B 2LXDA 2XJYA
chains in the Genus database with same CATH topology
2DFYC 4UF0B 3MMKA 2EGQA 4HI8B 2LZUA 2L6YB 4JCJA 1X6AA 4BHWA 2DARA 2O13A 4EYUA 1X3HA 4EZHA 1X64A 3NIMA 2JTNA 5LKXA 5FYMA 5FY7A 2KBXB 1RUTX 2XJZA 5FXXA 1B8TA 3NIKA 4KFZA 3NIJA 1V6GA 3AVSA 1G47A 2MIUA 1X4LA 3ZPOA 5A1LA 1WYHA 1U5SB 5FXVA 2CO8A 1CXXA 2XUEA 2DJ7A 2MBVA 3NISA 4EZ4A 2L4ZA 5FXWA 2L6ZC 2EHEA 2CUPA 5LKTA 2CORA 1WIGA 1IBIA 1M3VA 1X62A 1CTLA 3F6QB 2YPAC 2CUQA 3IXEB 2CURA 3NILA 2DLOA 5FY1A 1QLIA 1X63A 1X61A 3NINA 4UF0A 2D8ZA 2XQNT 1NYPA 5FY0A 5LKZA 3AVRA 5LKUA 3NIHA 5FP3A 1A7IA 1J2OA 3ZLIA 2IYBE 1IMLA 2D8XA 5FXZA 2CU8A 1X68A 2D8YA 4ASKA 2O10A 4HI9B 2LXDA 2XJYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CUP A;  2DFY C;  1X61 A;  4KFZ A;  2COR A;  1WIG A;  1V6G A;  3MMK A;  2EGQ A;  2D8Z A;  4HI8 B;  1G47 A;  2LZU A;  2XQN T;  1IBI A;  2L6Y B;  4JCJ A;  1X6A A;  1NYP A;  2DAR A;  2MIU A;  1X4L A;  2O13 A;  1X3H A;  1X64 A;  1A7I A;  1J2O A;  1WYH A;  1M3V A;  1U5S B;  1X62 A;  1CTL A;  2IYB E;  2JTN A;  2D8X A;  1IML A;  3F6Q B;  2YPA C;  2L4Z A;  2CU8 A;  2CO8 A;  2CUQ A;  1CXX A;  1X68 A;  2D8Y A;  2DJ7 A;  2KBX B;  2MBV A;  3IXE B;  1RUT X;  2O10 A;  2CUR A;  2XJZ A;  4HI9 B;  2DLO A;  2LXD A;  1QLI A;  1B8T A;  1X63 A;  2L6Z C;  2EHE A;  2XJY A; 
#chains in the Genus database with same CATH topology
 2DFY C;  4UF0 B;  3MMK A;  2EGQ A;  4HI8 B;  2LZU A;  2L6Y B;  4JCJ A;  1X6A A;  4BHW A;  2DAR A;  2O13 A;  4EYU A;  1X3H A;  4EZH A;  1X64 A;  3NIM A;  2JTN A;  5LKX A;  5FYM A;  5FY7 A;  2KBX B;  1RUT X;  2XJZ A;  5FXX A;  1B8T A;  3NIK A;  4KFZ A;  3NIJ A;  1V6G A;  3AVS A;  1G47 A;  2MIU A;  1X4L A;  3ZPO A;  5A1L A;  1WYH A;  1U5S B;  5FXV A;  2CO8 A;  1CXX A;  2XUE A;  2DJ7 A;  2MBV A;  3NIS A;  4EZ4 A;  2L4Z A;  5FXW A;  2L6Z C;  2EHE A;  2CUP A;  5LKT A;  2COR A;  1WIG A;  1IBI A;  1M3V A;  1X62 A;  1CTL A;  3F6Q B;  2YPA C;  2CUQ A;  3IXE B;  2CUR A;  3NIL A;  2DLO A;  5FY1 A;  1QLI A;  1X63 A;  1X61 A;  3NIN A;  4UF0 A;  2D8Z A;  2XQN T;  1NYP A;  5FY0 A;  5LKZ A;  3AVR A;  5LKU A;  3NIH A;  5FP3 A;  1A7I A;  1J2O A;  3ZLI A;  2IYB E;  1IML A;  2D8X A;  5FXZ A;  2CU8 A;  1X68 A;  2D8Y A;  4ASK A;  2O10 A;  4HI9 B;  2LXD A;  2XJY A; 
#chains in the Genus database with same CATH homology
 2DFY C;  4UF0 B;  3MMK A;  2EGQ A;  4HI8 B;  2LZU A;  2L6Y B;  4JCJ A;  1X6A A;  4BHW A;  2DAR A;  2O13 A;  4EYU A;  1X3H A;  4EZH A;  1X64 A;  3NIM A;  2JTN A;  5LKX A;  5FYM A;  5FY7 A;  2KBX B;  1RUT X;  2XJZ A;  5FXX A;  1B8T A;  3NIK A;  4KFZ A;  3NIJ A;  1V6G A;  3AVS A;  1G47 A;  2MIU A;  1X4L A;  3ZPO A;  5A1L A;  1WYH A;  1U5S B;  5FXV A;  2CO8 A;  1CXX A;  2XUE A;  2DJ7 A;  2MBV A;  3NIS A;  4EZ4 A;  2L4Z A;  5FXW A;  2L6Z C;  2EHE A;  2CUP A;  5LKT A;  2COR A;  1WIG A;  1IBI A;  1M3V A;  1X62 A;  1CTL A;  3F6Q B;  2YPA C;  2CUQ A;  3IXE B;  2CUR A;  3NIL A;  2DLO A;  5FY1 A;  1QLI A;  1X63 A;  1X61 A;  3NIN A;  4UF0 A;  2D8Z A;  2XQN T;  1NYP A;  5FY0 A;  5LKZ A;  3AVR A;  5LKU A;  3NIH A;  5FP3 A;  1A7I A;  1J2O A;  3ZLI A;  2IYB E;  1IML A;  2D8X A;  5FXZ A;  2CU8 A;  1X68 A;  2D8Y A;  4ASK A;  2O10 A;  4HI9 B;  2LXD A;  2XJY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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