1Y1VE

Refined rna polymerase ii-tfiis complex
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transcription
source organism Saccharomyces cerevisiae
publication title Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 47
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2004-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 1y1vE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 1y1vE02
3HKZH 3FKIE 1K83E 2R93E 4A3BE 3H3VF 4A3ME 4A93E 3GTGE 4C3IE 3I4ME 1TWHE 1TWFE 5C3EE 5M5WE 5M5YE 5IYDE 4C3HE 3S2HE 4A3GE 2NVQE 4BBRE 3RZOE 2VUME 4A3DE 1Y1VE 4BBSE 2WB1H 3HOXE 3S1NE 5FJ8E 1TWGE 4QIWH 1Y1WE 3HOWE 5C44E 4X6AE 3PO3E 1SFOE 4Y52E 3S15E 3GTPE 2R92E 5IYBE 3PO2E 2JA8E 1WCME 1EIKA 4A3JE 4BY7E 3M4OE 2PMZH 3HOVE 2WAQH 1DZFA 3HOYE 2E2IE 4A3LE 2E2HE 2E2JE 2YU9E 1I50E 3CQZE 3S2DE 3K7AE 3GTQE 1I3QE 2Y0SH 3GTOE 4AYBH 2B63E 3HOZE 3S16E 2NVYE 3GTME 5M3FE 2NVTE 3M3YE 4BY1E 4A3KE 5C4JE 3GTLE 4Y7NE 5FLME 1I6HE 3HOUE 3S1QE 4A3CE 5IYCE 5IP7E 5C4XE 3I4NE 4BXXE 3GTKE 2R7ZE 2NVXE 1R9TE 4A3FE 3S1ME 5IP9E 3S17E 5M3ME 2JA7E 2JA5E 4C2ME 3GTJE 5M5XE 3S14E 2JA6E 4C3JE 3H0GE 4A3IE 3RZDE 1TWAE 1TWCE 4A3EE 3S1RE
chains in the Genus database with same CATH superfamily
3HKZH 4C3IF 3FKIE 1K83E 2R93E 3I4MF 4A3BE 4MEYE 3H3VF 1TWHF 4A3ME 1TWFF 4AYBK 5C3EF 4A93E 4G7OE 5M5WF 3GTGE 5M5YF 5IPLE 4YFKE 2A6HE 2R92F 5IYDF 4C3IE 4KN4E 2Y0SI 5E18E 3S2HF 3I4ME 3PO2F 4ZH4E 2NVQF 1TWHE 1TWFE 4BBRF 5C3EE 2VUMF 3RZOF 5M5WE 4A3DF 5M5YE 5IYDE 4BBSF 4GZYE 4C3HE 3S2HE 2PPBE 4OIOE 2WAQK 4A3GE 3HOXF 2NVQE 5TMFE 4BBRE 3RZOE 2VUME 1QKLA 3HOVF 4MEXE 4A3DE 3S1NF 5FJ8F 1Y1VE 4BBSE 1TWGF 2WB1H 1Y1WF 5C44F 3HOXE 3S1NE 5FJ8E 4X6AF 1TWGE 4QIWH 4G7HE 1Y1WE 3PO3F 3HOWE 5C44E 1YNJK 1SFOF 4Y52F 3DXJE 3S15F 3GTPF 4X6AE 5IYBF 3PO3E 3S16F 2NVYF 1SFOE 4Q4ZE 2JA8F 4Y52E 2KRXA 2WB1I 3S15E 5E17E 3M3YF 1WCMF 3GTPE 2R92E 4A3KF 5IYBE 3PO2E 4A3JF 4BY7F 5D4DE 2JA8E 3M4OF 2O5IE 1WCME 4OIPE 3HOYF 1EIKA 4Q5SE 4JK1E 4YG2E 2E2IF 4A3JE 3EQLE 4BY7E 4A3LF 4LLGE 3M4OE 2PMZH 2E2HF 3HOVE 2WAQH 3GTKF 1IW7E 2E2JF 2YU9F 2NVXF 1DZFA 3HOYE 2O5JE 1I50F 1R9TF 2E2IE 3CQZF 4KN7E 3S1MF 4XSZE 3S2DF 4A3LE 3K7AF 5D4CE 3GTQF 2E2HE 1I3QF 2JA7F 2E2JE 2YU9E 3GTOF 1SMYE 1I50E 2B63F 3HOZF 3CQZE 1ZYRE 2CW0E 5M5XF 3S2DE 2A69E 4MQ9E 3K7AE 3GTQE 5D4EE 3GTMF 5M3FF 2NVTF 4XLPE 1I3QE 2Y0SH 3HKZK 3WODE 3GTOE 5TMCE 4BY1F 4AYBH 2B63E 3HOZE 3H3VG 1YNNK 2BE5E 4Y7NF 5FLMF 5C4JF 3S16E 2NVYE 3GTLF 3GTME 4A3BF 5M3FE 2NVTE 1I6HF 4KMUE 3HOUF 3M3YE 3S1QF 3GTGF 4BY1E 4A3CF 4A3KE 5IYCF 5C4JE 3GTLE 4Y7NE 5FLME 4LK0E 5IP7F 5C4XF 1I6HE 3I4NF 4BXXF 2R7ZF 3HOUE 3S1QE 4A3CE 4OIRE 4XSXE 5IYCE 4LJZE 4A3FF 4YFNE 5IP9F 4G7ZE 5M3MF 4C3HF 4XLNE 4LK1E 5IP7E 5C4XE 3S17F 4A3GF 3I4NE 4BXXE 2A68E 3GTKE 2R7ZE 2JA5F 2NVXE 4YFXE 1R9TE 4C2MF 3GTJF 4A3FE 3S1ME 5IP9E 3S17E 5M3ME 1Y1VF 2PMZK 2JA6F 3S14F 4C3JF 3H0GF 4A3IF 3RZDF 2JA7E 2JA5E 1TWCF 1TWAF 4QIWK 4A3EF 4C2ME 3S1RF 2A6EE 3GTJE 5M5XE 3S14E 3FKIF 1K83F 2R93F 2JA6E 1HQME 3HOWF 1I6VE 4C3JE 4OIQE 4OINE 3H0GE 4A3IE 4A3MF 3RZDE 5BYHE 1TWAE 1TWCE 4A93F 4A3EE 3S1RE
chains in the Genus database with same CATH topology
3HKZH 3FKIE 1K83E 2R93E 4A3BE 3H3VF 4A3ME 4A93E 3GTGE 4C3IE 3I4ME 1TWHE 1TWFE 5C3EE 5M5WE 5M5YE 5IYDE 4C3HE 3S2HE 4A3GE 2NVQE 4BBRE 3RZOE 2VUME 4A3DE 1Y1VE 4BBSE 2WB1H 3HOXE 3S1NE 5FJ8E 1TWGE 4QIWH 1Y1WE 3HOWE 5C44E 4X6AE 3PO3E 1SFOE 4Y52E 3S15E 3GTPE 2R92E 5IYBE 3PO2E 2JA8E 1WCME 1EIKA 4A3JE 4BY7E 3M4OE 2PMZH 3HOVE 2WAQH 1DZFA 3HOYE 2E2IE 4A3LE 2E2HE 2E2JE 2YU9E 1I50E 3CQZE 3S2DE 3K7AE 3GTQE 1I3QE 2Y0SH 3GTOE 4AYBH 2B63E 3HOZE 3S16E 2NVYE 3GTME 5M3FE 2NVTE 3M3YE 4BY1E 4A3KE 5C4JE 3GTLE 4Y7NE 5FLME 1I6HE 3HOUE 3S1QE 4A3CE 5IYCE 5IP7E 5C4XE 3I4NE 4BXXE 3GTKE 2R7ZE 2NVXE 1R9TE 4A3FE 3S1ME 5IP9E 3S17E 5M3ME 2JA7E 2JA5E 4C2ME 3GTJE 5M5XE 3S14E 2JA6E 4C3JE 3H0GE 4A3IE 3RZDE 1TWAE 1TWCE 4A3EE 3S1RE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HKZ H;  3FKI E;  1K83 E;  2R93 E;  4A3B E;  3H3V F;  4A3M E;  4A93 E;  3GTG E;  4C3I E;  3I4M E;  1TWH E;  1TWF E;  5C3E E;  5M5W E;  5M5Y E;  5IYD E;  4C3H E;  3S2H E;  4A3G E;  2NVQ E;  4BBR E;  3RZO E;  2VUM E;  4A3D E;  1Y1V E;  4BBS E;  2WB1 H;  3HOX E;  3S1N E;  5FJ8 E;  1TWG E;  4QIW H;  1Y1W E;  3HOW E;  5C44 E;  4X6A E;  3PO3 E;  1SFO E;  4Y52 E;  3S15 E;  3GTP E;  2R92 E;  5IYB E;  3PO2 E;  2JA8 E;  1WCM E;  1EIK A;  4A3J E;  4BY7 E;  3M4O E;  2PMZ H;  3HOV E;  2WAQ H;  1DZF A;  3HOY E;  2E2I E;  4A3L E;  2E2H E;  2E2J E;  2YU9 E;  1I50 E;  3CQZ E;  3S2D E;  3K7A E;  3GTQ E;  1I3Q E;  2Y0S H;  3GTO E;  4AYB H;  2B63 E;  3HOZ E;  3S16 E;  2NVY E;  3GTM E;  5M3F E;  2NVT E;  3M3Y E;  4BY1 E;  4A3K E;  5C4J E;  3GTL E;  4Y7N E;  5FLM E;  1I6H E;  3HOU E;  3S1Q E;  4A3C E;  5IYC E;  5IP7 E;  5C4X E;  3I4N E;  4BXX E;  3GTK E;  2R7Z E;  2NVX E;  1R9T E;  4A3F E;  3S1M E;  5IP9 E;  3S17 E;  5M3M E;  2JA7 E;  2JA5 E;  4C2M E;  3GTJ E;  5M5X E;  3S14 E;  2JA6 E;  4C3J E;  3H0G E;  4A3I E;  3RZD E;  1TWA E;  1TWC E;  4A3E E;  3S1R E; 
#chains in the Genus database with same CATH topology
 3HKZ H;  4C3I F;  3FKI E;  1K83 E;  2R93 E;  3I4M F;  4A3B E;  4MEY E;  3H3V F;  1TWH F;  4A3M E;  1TWF F;  4AYB K;  5C3E F;  4A93 E;  4G7O E;  5M5W F;  3GTG E;  5M5Y F;  5IPL E;  4YFK E;  2A6H E;  2R92 F;  5IYD F;  4C3I E;  4KN4 E;  2Y0S I;  5E18 E;  3S2H F;  3I4M E;  3PO2 F;  4ZH4 E;  2NVQ F;  1TWH E;  1TWF E;  4BBR F;  5C3E E;  2VUM F;  3RZO F;  5M5W E;  4A3D F;  5M5Y E;  5IYD E;  4BBS F;  4GZY E;  4C3H E;  3S2H E;  2PPB E;  4OIO E;  2WAQ K;  4A3G E;  3HOX F;  2NVQ E;  5TMF E;  4BBR E;  3RZO E;  2VUM E;  1QKL A;  3HOV F;  4MEX E;  4A3D E;  3S1N F;  5FJ8 F;  1Y1V E;  4BBS E;  1TWG F;  2WB1 H;  1Y1W F;  5C44 F;  3HOX E;  3S1N E;  5FJ8 E;  4X6A F;  1TWG E;  4QIW H;  4G7H E;  1Y1W E;  3PO3 F;  3HOW E;  5C44 E;  1YNJ K;  1SFO F;  4Y52 F;  3DXJ E;  3S15 F;  3GTP F;  4X6A E;  5IYB F;  3PO3 E;  3S16 F;  2NVY F;  1SFO E;  4Q4Z E;  2JA8 F;  4Y52 E;  2KRX A;  2WB1 I;  3S15 E;  5E17 E;  3M3Y F;  1WCM F;  3GTP E;  2R92 E;  4A3K F;  5IYB E;  3PO2 E;  4A3J F;  4BY7 F;  5D4D E;  2JA8 E;  3M4O F;  2O5I E;  1WCM E;  4OIP E;  3HOY F;  1EIK A;  4Q5S E;  4JK1 E;  4YG2 E;  2E2I F;  4A3J E;  3EQL E;  4BY7 E;  4A3L F;  4LLG E;  3M4O E;  2PMZ H;  2E2H F;  3HOV E;  2WAQ H;  3GTK F;  1IW7 E;  2E2J F;  2YU9 F;  2NVX F;  1DZF A;  3HOY E;  2O5J E;  1I50 F;  1R9T F;  2E2I E;  3CQZ F;  4KN7 E;  3S1M F;  4XSZ E;  3S2D F;  4A3L E;  3K7A F;  5D4C E;  3GTQ F;  2E2H E;  1I3Q F;  2JA7 F;  2E2J E;  2YU9 E;  3GTO F;  1SMY E;  1I50 E;  2B63 F;  3HOZ F;  3CQZ E;  1ZYR E;  2CW0 E;  5M5X F;  3S2D E;  2A69 E;  4MQ9 E;  3K7A E;  3GTQ E;  5D4E E;  3GTM F;  5M3F F;  2NVT F;  4XLP E;  1I3Q E;  2Y0S H;  3HKZ K;  3WOD E;  3GTO E;  5TMC E;  4BY1 F;  4AYB H;  2B63 E;  3HOZ E;  3H3V G;  1YNN K;  2BE5 E;  4Y7N F;  5FLM F;  5C4J F;  3S16 E;  2NVY E;  3GTL F;  3GTM E;  4A3B F;  5M3F E;  2NVT E;  1I6H F;  4KMU E;  3HOU F;  3M3Y E;  3S1Q F;  3GTG F;  4BY1 E;  4A3C F;  4A3K E;  5IYC F;  5C4J E;  3GTL E;  4Y7N E;  5FLM E;  4LK0 E;  5IP7 F;  5C4X F;  1I6H E;  3I4N F;  4BXX F;  2R7Z F;  3HOU E;  3S1Q E;  4A3C E;  4OIR E;  4XSX E;  5IYC E;  4LJZ E;  4A3F F;  4YFN E;  5IP9 F;  4G7Z E;  5M3M F;  4C3H F;  4XLN E;  4LK1 E;  5IP7 E;  5C4X E;  3S17 F;  4A3G F;  3I4N E;  4BXX E;  2A68 E;  3GTK E;  2R7Z E;  2JA5 F;  2NVX E;  4YFX E;  1R9T E;  4C2M F;  3GTJ F;  4A3F E;  3S1M E;  5IP9 E;  3S17 E;  5M3M E;  1Y1V F;  2PMZ K;  2JA6 F;  3S14 F;  4C3J F;  3H0G F;  4A3I F;  3RZD F;  2JA7 E;  2JA5 E;  1TWC F;  1TWA F;  4QIW K;  4A3E F;  4C2M E;  3S1R F;  2A6E E;  3GTJ E;  5M5X E;  3S14 E;  3FKI F;  1K83 F;  2R93 F;  2JA6 E;  1HQM E;  3HOW F;  1I6V E;  4C3J E;  4OIQ E;  4OIN E;  3H0G E;  4A3I E;  4A3M F;  3RZD E;  5BYH E;  1TWA E;  1TWC E;  4A93 F;  4A3E E;  3S1R E; 
#chains in the Genus database with same CATH homology
 3HKZ H;  3FKI E;  1K83 E;  2R93 E;  4A3B E;  3H3V F;  4A3M E;  4A93 E;  3GTG E;  4C3I E;  3I4M E;  1TWH E;  1TWF E;  5C3E E;  5M5W E;  5M5Y E;  5IYD E;  4C3H E;  3S2H E;  4A3G E;  2NVQ E;  4BBR E;  3RZO E;  2VUM E;  4A3D E;  1Y1V E;  4BBS E;  2WB1 H;  3HOX E;  3S1N E;  5FJ8 E;  1TWG E;  4QIW H;  1Y1W E;  3HOW E;  5C44 E;  4X6A E;  3PO3 E;  1SFO E;  4Y52 E;  3S15 E;  3GTP E;  2R92 E;  5IYB E;  3PO2 E;  2JA8 E;  1WCM E;  1EIK A;  4A3J E;  4BY7 E;  3M4O E;  2PMZ H;  3HOV E;  2WAQ H;  1DZF A;  3HOY E;  2E2I E;  4A3L E;  2E2H E;  2E2J E;  2YU9 E;  1I50 E;  3CQZ E;  3S2D E;  3K7A E;  3GTQ E;  1I3Q E;  2Y0S H;  3GTO E;  4AYB H;  2B63 E;  3HOZ E;  3S16 E;  2NVY E;  3GTM E;  5M3F E;  2NVT E;  3M3Y E;  4BY1 E;  4A3K E;  5C4J E;  3GTL E;  4Y7N E;  5FLM E;  1I6H E;  3HOU E;  3S1Q E;  4A3C E;  5IYC E;  5IP7 E;  5C4X E;  3I4N E;  4BXX E;  3GTK E;  2R7Z E;  2NVX E;  1R9T E;  4A3F E;  3S1M E;  5IP9 E;  3S17 E;  5M3M E;  2JA7 E;  2JA5 E;  4C2M E;  3GTJ E;  5M5X E;  3S14 E;  2JA6 E;  4C3J E;  3H0G E;  4A3I E;  3RZD E;  1TWA E;  1TWC E;  4A3E E;  3S1R E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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