1YNNK

Taq rna polymerase-rifampicin complex
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
95
structure length
95
Chain Sequence
MAEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHRFKNTVLEPEERPKMRTLEGLYDDPNAVTWAMKELLTGRLFFGENLVPEDRLQKEMERLYPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-directed RNA polymerase alpha chain
total genus 19
structure length 95
sequence length 95
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2005-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1ynnK00
5D4CE 4KN4E 4BY7F 4MQ9E 5IYBF 4KMUE 2NVTF 4OIPE 4OINE 2NVQF 1TWGF 4JK1E 4G7OE 5C44F 3FKIF 3RZOF 3GTQF 4Q4ZE 4BBSF 4MEYE 5IYCF 1TWCF 4XLPE 2A68E 4Y7NF 3HOUF 4YG2E 5FLMF 4A3MF 5IP9F 2A6EE 3K7AF 4LK1E 4A3EF 4A3LF 4Y52F 5TMCE 1SMYE 3GTGF 1QKLA 4C3HF 1HQME 2A69E 4BY1F 2A6HE 4ZH4E 3GTOF 4LJZE 3S2DF 3PO3F 1TWFF 1YNJK 2JA5F 1I3QF 2CW0E 3S1RF 2R7ZF 1Y1WF 5M5YF 3S16F 4XSXE 1YNNK 4A3JF 5M5WF 1I6VE 1SFOF 5C3EF 1WCMF 2JA8F 3GTPF 5E17E 3RZDF 2B63F 3H3VG 2R93F 4AYBK 1TWAF 2BE5E 2JA6F 4Q5SE 3GTJF 4BXXF 4YFNE 2WAQK 4OIRE 4G7HE 4A3CF 3GTLF 3I4NF 4OIOE 3HOZF 3HOXF 4A3DF 3DXJE 3I4MF 5M5XF 2E2IF 3HOWF 4C3IF 2WB1I 4A3IF 4A93F 4A3KF 3HOYF 5TMFE 1I50F 3WODE 3HKZK 3GTKF 2O5JE 4XLNE 5IYDF 1K83F 3S2HF 3PO2F 3M4OF 2PMZK 3CQZF 2E2HF 5E18E 2O5IE 2NVXF 5D4EE 4LLGE 4C3JF 3S15F 3S1QF 5C4JF 2VUMF 2E2JF 3S17F 4GZYE 1I6HF 4YFKE 2R92F 5M3FF 5M3MF 2PPBE 4BBRF 4A3FF 2Y0SI 3GTMF 4LK0E 1R9TF 3S14F 2NVYF 2YU9F 3S1MF 5BYHE 5IP7F 3M3YF 1IW7E 1TWHF 4YFXE 3HOVF 4X6AF 1Y1VF 5FJ8F 3S1NF 1ZYRE 5C4XF 4A3GF 5D4DE 3EQLE 4G7ZE 4OIQE 4XSZE 3H0GF 4C2MF 4A3BF 4MEXE 4KN7E 5IPLE 2JA7F
chains in the Genus database with same CATH superfamily
5D4CE 4KN4E 4BY7F 4MQ9E 5IYBF 3GTLE 4A3CE 4KMUE 4C3HE 2NVTF 4BY1E 3HOZE 4OIPE 3HOXE 4OINE 2NVQF 1TWGF 4JK1E 4G7OE 5M5XE 5C44F 2E2IE 3FKIF 3HOWE 3RZOF 3GTQF 4Q4ZE 4BBSF 4MEYE 4C3IE 1TWCF 1I3QE 5IYCF 4XLPE 3S1RE 2A68E 4Y7NF 4A3IE 3HOUF 4A93E 2R7ZE 1I50E 4YG2E 5M5YE 5FLMF 3S16E 4A3MF 1DZFA 5IP9F 5IYDE 1K83E 2A6EE 3S2HE 3K7AF 3PO2E 1SFOE 4LK1E 2JA8E 1WCME 3RZDE 4A3EF 2B63E 4A3LF 4Y52F 5TMCE 1SMYE 3GTGF 1QKLA 2R93E 4BXXE 4C3HF 1HQME 2A69E 4BY1F 4C3JE 3I4NE 2A6HE 3S1QE 5C4JE 3S17E 2E2JE 4ZH4E 3GTOF 1I6HE 4LJZE 4A3DE 2R92E 2KRXA 4BBRE 3S2DF 3GTME 3I4ME 3PO3F 1TWFF 1YNJK 1R9TE 2JA5F 3S14E 1I3QF 2CW0E 2Y0SH 3S1ME 3S1RF 3HOVE 4X6AE 2R7ZF 1Y1WF 1Y1VE 5FJ8E 5M5YF 4A3KE 3S16F 4XSXE 3HOYE 1YNNK 4A3JF 5C4XE 5M5WF 3GTKE 1I6VE 1SFOF 5C3EF 1WCMF 2JA8F 3GTPF 5E17E 3RZDF 3M4OE 2B63F 1EIKA 3CQZE 3H3VG 2E2HE 2R93F 4AYBK 1TWAF 2BE5E 2JA6F 4Q5SE 3GTJF 4BXXF 4YFNE 2WAQK 4OIRE 4G7HE 2NVTE 3GTLF 3I4NF 4A3CF 2NVXE 4OIOE 2NVQE 3HOZF 3S15E 3HOXF 2VUME 4A3DF 2WAQH 5C44E 3DXJE 3FKIE 5M3FE 3I4MF 5M3ME 5M5XF 4A3FE 2E2IF 4BBSE 3HOWF 4C3IF 2NVYE 2WB1I 4Y7NE 2YU9E 5IP7E 3M3YE 1TWHE 4A3IF 4A93F 4A3KF 3HOYF 4A3ME 5TMFE 1I50F 3WODE 3HKZK 3GTKF 5IP9E 3S1NE 2O5JE 4XLNE 3K7AE 4A3GE 5IYDF 1K83F 3S2HF 3PO2F 3M4OF 3H0GE 4C2ME 4A3EE 2PMZK 3HKZH 4A3BE 4A3LE 3CQZF 4Y52E 2E2HF 3GTGE 4QIWK 5E18E 2PMZH 2JA7E 5IYBE 4BY7E 2O5IE 2NVXF 2YU9F 5D4EE 4LLGE 4QIWH 4C3JF 3S15F 4AYBH 3GTOE 5C4JF 2VUMF 2E2JF 3S17F 3S1QF 4GZYE 1I6HF 1TWGE 4YFKE 2R92F 5M3FF 3S2DE 3PO3E 5M3MF 2PPBE 1TWFE 4BBRF 4A3FF 2JA5E 2Y0SI 3GTMF 3RZOE 4LK0E 3GTQE 1R9TF 3S14F 2NVYF 2WB1H 1TWCE 5IYCE 5BYHE 5IP7F 1IW7E 1TWHF 4YFXE 1Y1WE 3HOVF 3HOUE 3M3YF 4X6AF 1Y1VF 5FJ8F 4A3JE 5FLME 5M5WE 1ZYRE 3S1NF 5C4XF 3H3VF 4A3GF 5D4DE 3EQLE 5C3EE 4G7ZE 4OIQE 3GTPE 4XSZE 3H0GF 4C2MF 4A3BF 4MEXE 1TWAE 3S1MF 2JA6E 4KN7E 3GTJE 5IPLE 2JA7F
chains in the Genus database with same CATH topology
5D4CE 4KN4E 4BY7F 4MQ9E 5IYBF 4KMUE 2NVTF 4OIPE 4OINE 2NVQF 1TWGF 4JK1E 4G7OE 5C44F 3FKIF 3RZOF 3GTQF 4Q4ZE 4BBSF 4MEYE 5IYCF 1TWCF 4XLPE 2A68E 4Y7NF 3HOUF 4YG2E 5FLMF 4A3MF 5IP9F 2A6EE 3K7AF 4LK1E 4A3EF 4A3LF 4Y52F 5TMCE 1SMYE 3GTGF 1QKLA 4C3HF 1HQME 2A69E 4BY1F 2A6HE 4ZH4E 3GTOF 4LJZE 2KRXA 3S2DF 3PO3F 1TWFF 1YNJK 2JA5F 1I3QF 2CW0E 3S1RF 2R7ZF 1Y1WF 5M5YF 3S16F 4XSXE 1YNNK 4A3JF 5M5WF 1I6VE 1SFOF 5C3EF 1WCMF 2JA8F 3GTPF 5E17E 3RZDF 2B63F 3H3VG 2R93F 4AYBK 1TWAF 2BE5E 2JA6F 4Q5SE 3GTJF 4BXXF 4YFNE 2WAQK 4OIRE 4G7HE 4A3CF 3GTLF 3I4NF 4OIOE 3HOZF 3HOXF 4A3DF 3DXJE 3I4MF 5M5XF 2E2IF 3HOWF 4C3IF 2WB1I 4A3IF 4A93F 4A3KF 3HOYF 5TMFE 1I50F 3WODE 3HKZK 3GTKF 2O5JE 4XLNE 5IYDF 1K83F 3S2HF 3PO2F 3M4OF 2PMZK 3CQZF 2E2HF 4QIWK 5E18E 2O5IE 2NVXF 5D4EE 4LLGE 4C3JF 3S15F 3S1QF 5C4JF 2VUMF 2E2JF 3S17F 4GZYE 1I6HF 4YFKE 2R92F 5M3FF 5M3MF 2PPBE 4BBRF 4A3FF 2Y0SI 3GTMF 4LK0E 1R9TF 3S14F 2NVYF 2YU9F 3S1MF 5BYHE 5IP7F 3M3YF 1IW7E 1TWHF 4YFXE 3HOVF 4X6AF 1Y1VF 5FJ8F 3S1NF 1ZYRE 5C4XF 4A3GF 5D4DE 3EQLE 4G7ZE 4OIQE 4XSZE 3H0GF 4C2MF 4A3BF 4MEXE 4KN7E 5IPLE 2JA7F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D4C E;  4KN4 E;  4BY7 F;  4MQ9 E;  5IYB F;  4KMU E;  2NVT F;  4OIP E;  4OIN E;  2NVQ F;  1TWG F;  4JK1 E;  4G7O E;  5C44 F;  3FKI F;  3RZO F;  3GTQ F;  4Q4Z E;  4BBS F;  4MEY E;  5IYC F;  1TWC F;  4XLP E;  2A68 E;  4Y7N F;  3HOU F;  4YG2 E;  5FLM F;  4A3M F;  5IP9 F;  2A6E E;  3K7A F;  4LK1 E;  4A3E F;  4A3L F;  4Y52 F;  5TMC E;  1SMY E;  3GTG F;  1QKL A;  4C3H F;  1HQM E;  2A69 E;  4BY1 F;  2A6H E;  4ZH4 E;  3GTO F;  4LJZ E;  3S2D F;  3PO3 F;  1TWF F;  1YNJ K;  2JA5 F;  1I3Q F;  2CW0 E;  3S1R F;  2R7Z F;  1Y1W F;  5M5Y F;  3S16 F;  4XSX E;  1YNN K;  4A3J F;  5M5W F;  1I6V E;  1SFO F;  5C3E F;  1WCM F;  2JA8 F;  3GTP F;  5E17 E;  3RZD F;  2B63 F;  3H3V G;  2R93 F;  4AYB K;  1TWA F;  2BE5 E;  2JA6 F;  4Q5S E;  3GTJ F;  4BXX F;  4YFN E;  2WAQ K;  4OIR E;  4G7H E;  4A3C F;  3GTL F;  3I4N F;  4OIO E;  3HOZ F;  3HOX F;  4A3D F;  3DXJ E;  3I4M F;  5M5X F;  2E2I F;  3HOW F;  4C3I F;  2WB1 I;  4A3I F;  4A93 F;  4A3K F;  3HOY F;  5TMF E;  1I50 F;  3WOD E;  3HKZ K;  3GTK F;  2O5J E;  4XLN E;  5IYD F;  1K83 F;  3S2H F;  3PO2 F;  3M4O F;  2PMZ K;  3CQZ F;  2E2H F;  5E18 E;  2O5I E;  2NVX F;  5D4E E;  4LLG E;  4C3J F;  3S15 F;  3S1Q F;  5C4J F;  2VUM F;  2E2J F;  3S17 F;  4GZY E;  1I6H F;  4YFK E;  2R92 F;  5M3F F;  5M3M F;  2PPB E;  4BBR F;  4A3F F;  2Y0S I;  3GTM F;  4LK0 E;  1R9T F;  3S14 F;  2NVY F;  2YU9 F;  3S1M F;  5BYH E;  5IP7 F;  3M3Y F;  1IW7 E;  1TWH F;  4YFX E;  3HOV F;  4X6A F;  1Y1V F;  5FJ8 F;  3S1N F;  1ZYR E;  5C4X F;  4A3G F;  5D4D E;  3EQL E;  4G7Z E;  4OIQ E;  4XSZ E;  3H0G F;  4C2M F;  4A3B F;  4MEX E;  4KN7 E;  5IPL E;  2JA7 F; 
#chains in the Genus database with same CATH topology
 5D4C E;  4KN4 E;  4BY7 F;  4MQ9 E;  5IYB F;  3GTL E;  4A3C E;  4KMU E;  4C3H E;  2NVT F;  4BY1 E;  3HOZ E;  4OIP E;  3HOX E;  4OIN E;  2NVQ F;  1TWG F;  4JK1 E;  4G7O E;  5M5X E;  5C44 F;  2E2I E;  3FKI F;  3HOW E;  3RZO F;  3GTQ F;  4Q4Z E;  4BBS F;  4MEY E;  4C3I E;  1TWC F;  1I3Q E;  5IYC F;  4XLP E;  3S1R E;  2A68 E;  4Y7N F;  4A3I E;  3HOU F;  4A93 E;  2R7Z E;  1I50 E;  4YG2 E;  5M5Y E;  5FLM F;  3S16 E;  4A3M F;  1DZF A;  5IP9 F;  5IYD E;  1K83 E;  2A6E E;  3S2H E;  3K7A F;  3PO2 E;  1SFO E;  4LK1 E;  2JA8 E;  1WCM E;  3RZD E;  4A3E F;  2B63 E;  4A3L F;  4Y52 F;  5TMC E;  1SMY E;  3GTG F;  1QKL A;  2R93 E;  4BXX E;  4C3H F;  1HQM E;  2A69 E;  4BY1 F;  4C3J E;  3I4N E;  2A6H E;  3S1Q E;  5C4J E;  3S17 E;  2E2J E;  4ZH4 E;  3GTO F;  1I6H E;  4LJZ E;  4A3D E;  2R92 E;  2KRX A;  4BBR E;  3S2D F;  3GTM E;  3I4M E;  3PO3 F;  1TWF F;  1YNJ K;  1R9T E;  2JA5 F;  3S14 E;  1I3Q F;  2CW0 E;  2Y0S H;  3S1M E;  3S1R F;  3HOV E;  4X6A E;  2R7Z F;  1Y1W F;  1Y1V E;  5FJ8 E;  5M5Y F;  4A3K E;  3S16 F;  4XSX E;  3HOY E;  1YNN K;  4A3J F;  5C4X E;  5M5W F;  3GTK E;  1I6V E;  1SFO F;  5C3E F;  1WCM F;  2JA8 F;  3GTP F;  5E17 E;  3RZD F;  3M4O E;  2B63 F;  1EIK A;  3CQZ E;  3H3V G;  2E2H E;  2R93 F;  4AYB K;  1TWA F;  2BE5 E;  2JA6 F;  4Q5S E;  3GTJ F;  4BXX F;  4YFN E;  2WAQ K;  4OIR E;  4G7H E;  2NVT E;  3GTL F;  3I4N F;  4A3C F;  2NVX E;  4OIO E;  2NVQ E;  3HOZ F;  3S15 E;  3HOX F;  2VUM E;  4A3D F;  2WAQ H;  5C44 E;  3DXJ E;  3FKI E;  5M3F E;  3I4M F;  5M3M E;  5M5X F;  4A3F E;  2E2I F;  4BBS E;  3HOW F;  4C3I F;  2NVY E;  2WB1 I;  4Y7N E;  2YU9 E;  5IP7 E;  3M3Y E;  1TWH E;  4A3I F;  4A93 F;  4A3K F;  3HOY F;  4A3M E;  5TMF E;  1I50 F;  3WOD E;  3HKZ K;  3GTK F;  5IP9 E;  3S1N E;  2O5J E;  4XLN E;  3K7A E;  4A3G E;  5IYD F;  1K83 F;  3S2H F;  3PO2 F;  3M4O F;  3H0G E;  4C2M E;  4A3E E;  2PMZ K;  3HKZ H;  4A3B E;  4A3L E;  3CQZ F;  4Y52 E;  2E2H F;  3GTG E;  4QIW K;  5E18 E;  2PMZ H;  2JA7 E;  5IYB E;  4BY7 E;  2O5I E;  2NVX F;  2YU9 F;  5D4E E;  4LLG E;  4QIW H;  4C3J F;  3S15 F;  4AYB H;  3GTO E;  5C4J F;  2VUM F;  2E2J F;  3S17 F;  3S1Q F;  4GZY E;  1I6H F;  1TWG E;  4YFK E;  2R92 F;  5M3F F;  3S2D E;  3PO3 E;  5M3M F;  2PPB E;  1TWF E;  4BBR F;  4A3F F;  2JA5 E;  2Y0S I;  3GTM F;  3RZO E;  4LK0 E;  3GTQ E;  1R9T F;  3S14 F;  2NVY F;  2WB1 H;  1TWC E;  5IYC E;  5BYH E;  5IP7 F;  1IW7 E;  1TWH F;  4YFX E;  1Y1W E;  3HOV F;  3HOU E;  3M3Y F;  4X6A F;  1Y1V F;  5FJ8 F;  4A3J E;  5FLM E;  5M5W E;  1ZYR E;  3S1N F;  5C4X F;  3H3V F;  4A3G F;  5D4D E;  3EQL E;  5C3E E;  4G7Z E;  4OIQ E;  3GTP E;  4XSZ E;  3H0G F;  4C2M F;  4A3B F;  4MEX E;  1TWA E;  3S1M F;  2JA6 E;  4KN7 E;  3GTJ E;  5IPL E;  2JA7 F; 
#chains in the Genus database with same CATH homology
 5D4C E;  4KN4 E;  4BY7 F;  4MQ9 E;  5IYB F;  4KMU E;  2NVT F;  4OIP E;  4OIN E;  2NVQ F;  1TWG F;  4JK1 E;  4G7O E;  5C44 F;  3FKI F;  3RZO F;  3GTQ F;  4Q4Z E;  4BBS F;  4MEY E;  5IYC F;  1TWC F;  4XLP E;  2A68 E;  4Y7N F;  3HOU F;  4YG2 E;  5FLM F;  4A3M F;  5IP9 F;  2A6E E;  3K7A F;  4LK1 E;  4A3E F;  4A3L F;  4Y52 F;  5TMC E;  1SMY E;  3GTG F;  1QKL A;  4C3H F;  1HQM E;  2A69 E;  4BY1 F;  2A6H E;  4ZH4 E;  3GTO F;  4LJZ E;  2KRX A;  3S2D F;  3PO3 F;  1TWF F;  1YNJ K;  2JA5 F;  1I3Q F;  2CW0 E;  3S1R F;  2R7Z F;  1Y1W F;  5M5Y F;  3S16 F;  4XSX E;  1YNN K;  4A3J F;  5M5W F;  1I6V E;  1SFO F;  5C3E F;  1WCM F;  2JA8 F;  3GTP F;  5E17 E;  3RZD F;  2B63 F;  3H3V G;  2R93 F;  4AYB K;  1TWA F;  2BE5 E;  2JA6 F;  4Q5S E;  3GTJ F;  4BXX F;  4YFN E;  2WAQ K;  4OIR E;  4G7H E;  4A3C F;  3GTL F;  3I4N F;  4OIO E;  3HOZ F;  3HOX F;  4A3D F;  3DXJ E;  3I4M F;  5M5X F;  2E2I F;  3HOW F;  4C3I F;  2WB1 I;  4A3I F;  4A93 F;  4A3K F;  3HOY F;  5TMF E;  1I50 F;  3WOD E;  3HKZ K;  3GTK F;  2O5J E;  4XLN E;  5IYD F;  1K83 F;  3S2H F;  3PO2 F;  3M4O F;  2PMZ K;  3CQZ F;  2E2H F;  4QIW K;  5E18 E;  2O5I E;  2NVX F;  5D4E E;  4LLG E;  4C3J F;  3S15 F;  3S1Q F;  5C4J F;  2VUM F;  2E2J F;  3S17 F;  4GZY E;  1I6H F;  4YFK E;  2R92 F;  5M3F F;  5M3M F;  2PPB E;  4BBR F;  4A3F F;  2Y0S I;  3GTM F;  4LK0 E;  1R9T F;  3S14 F;  2NVY F;  2YU9 F;  3S1M F;  5BYH E;  5IP7 F;  3M3Y F;  1IW7 E;  1TWH F;  4YFX E;  3HOV F;  4X6A F;  1Y1V F;  5FJ8 F;  3S1N F;  1ZYR E;  5C4X F;  4A3G F;  5D4D E;  3EQL E;  4G7Z E;  4OIQ E;  4XSZ E;  3H0G F;  4C2M F;  4A3B F;  4MEX E;  4KN7 E;  5IPL E;  2JA7 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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