1ADZ | Genus

Total Genus 7

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	7
sequence length	71
structure length	71
Chain Sequence	DYKDDDDKLKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5d29a95bd056fea708a81bf6/pdb.gz

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The Resolver thinks Pdb

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Time for openFile(/file/5d29a95bd056fea708a81bf6/pdb.gz): 2159 ms

reading 71 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

71 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 16 ms

Adding embedded #jmolscript: select ({0:70});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa. pubmed doi rcsb
molecule keywords	TISSUE FACTOR PATHWAY INHIBITOR
total genus	7
structure length	71
sequence length	71
ec nomenclature
pdb deposition date	1997-02-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00014	Kunitz_BPTI	Kunitz/Bovine pancreatic trypsin inhibitor domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
4.10.410.10	Few Secondary Structures	Irregular	Factor Xa Inhibitor	Pancreatic trypsin inhibitor Kunitz domain	1adzA00

1BUNB 3BTQI 1TAWB 1TFXC 1BPIA 3BTDI 1OA65 2TPII 4BD9B 3OTJI 8PTIA 1EAWB 2LFKA 1DTXA 1TAPA 1YKTB 1QLQA 1UUBA 1G6XA 1T8LB 1AAPA 1LD6A 3AUCA 1BF0A 4BQDA 2KCRA 1BTHP 2DDIA 3BTTI 3LDMA 1IRHA 4ISLB 1BTIA 1KNTA 3UIRC 1AALA 5JB5A 3UOUB 3U1JE 3LDIA 3BTKI 1P2NB 4Y11I 1JV8A 2PTCI 5C67C 3AUDA 3BTFI 1F7ZI 4Y10I 3AUIA 2KAII 3L3TE 1P2QB 1P2JI 1DTKA 3TGJI 2TGPI 2JOTA 1CA0D 4BNRI 1BIKA 4ISOB 1FANA 3L33E 1NAGA 4WWYC 1D0DB 3D65I 1PITA 4WXVC 3WNYA 4ISNB 1SHPA 2ODYE 1BRCI 3P92E 1BZXI 1T8NB 3TGKI 5JB6A 3TPII 1TCPA 3BTHI 2IJOI 5PTIA 3GYMI 3FP8I 3BTGI 1EJMB 2R9PE 3BYBA 1BPTA 2DDJA 6PTIA 4PTIA 4NTYB 1LD5A 1UUAA 1BHCA 3AUEA 2M99A 1FY8I 1FAKI 3CI7A 1P2OB 1P2KI 1JV9A 2ZVXA 3BTEI 1F5RI 1KIGI 2FTMB 4NTXB 4NTWB 3T62D 4DG4C 9PTIA 1YC0I 1K6UA 1JC6A 2UUXA 2ZJXA 2LFLA 2HEXA 1P2II 3LDJA 4TPII 1DENA 1BZ5A 1Y62A 3AUBA 1MTND 2RA3C 1DEMA 1D0DA 2FI4I 1CO7I 1CBWD 3AUGA 3M7QB 2W8XA 3FP6I 1KTHA 1P2MB 2UUYB 4DTGK 2KNTA 3BTWI 1TOCR 1YLCB 1TPAI 3TGII 1ADZA 1T8OB 4U32X 2FI3I 1ZR0B 1ZJDB 4U30W 1T8MB 3FP7J 1YLDB 1KUNA 1BRBI 4Y0ZI 2CA7A 5JB4A 2FTLI 2M01A 1B0CA 3P95E 4Y0YI 3OFWA 2FI5I 1T7CB 5JB7A 7PTIA 3BTMI 2J6DA 3AUHA 1OA55
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1BUN B;  3BTQ I;  1TAW B;  1TFX C;  1BPI A;  3BTD I;  1OA6 5;  2TPI I;  4BD9 B;  3OTJ I;  8PTI A;  1EAW B;  2LFK A;  1DTX A;  1TAP A;  1YKT B;  1QLQ A;  1UUB A;  1G6X A;  1T8L B;  1AAP A;  1LD6 A;  3AUC A;  1BF0 A;  4BQD A;  2KCR A;  1BTH P;  2DDI A;  3BTT I;  3LDM A;  1IRH A;  4ISL B;  1BTI A;  1KNT A;  3UIR C;  1AAL A;  5JB5 A;  3UOU B;  3U1J E;  3LDI A;  3BTK I;  1P2N B;  4Y11 I;  1JV8 A;  2PTC I;  5C67 C;  3AUD A;  3BTF I;  1F7Z I;  4Y10 I;  3AUI A;  2KAI I;  3L3T E;  1P2Q B;  1P2J I;  1DTK A;  3TGJ I;  2TGP I;  2JOT A;  1CA0 D;  4BNR I;  1BIK A;  4ISO B;  1FAN A;  3L33 E;  1NAG A;  4WWY C;  1D0D B;  3D65 I;  1PIT A;  4WXV C;  3WNY A;  4ISN B;  1SHP A;  2ODY E;  1BRC I;  3P92 E;  1BZX I;  1T8N B;  3TGK I;  5JB6 A;  3TPI I;  1TCP A;  3BTH I;  2IJO I;  5PTI A;  3GYM I;  3FP8 I;  3BTG I;  1EJM B;  2R9P E;  3BYB A;  1BPT A;  2DDJ A;  6PTI A;  4PTI A;  4NTY B;  1LD5 A;  1UUA A;  1BHC A;  3AUE A;  2M99 A;  1FY8 I;  1FAK I;  3CI7 A;  1P2O B;  1P2K I;  1JV9 A;  2ZVX A;  3BTE I;  1F5R I;  1KIG I;  2FTM B;  4NTX B;  4NTW B;  3T62 D;  4DG4 C;  9PTI A;  1YC0 I;  1K6U A;  1JC6 A;  2UUX A;  2ZJX A;  2LFL A;  2HEX A;  1P2I I;  3LDJ A;  4TPI I;  1DEN A;  1BZ5 A;  1Y62 A;  3AUB A;  1MTN D;  2RA3 C;  1DEM A;  1D0D A;  2FI4 I;  1CO7 I;  1CBW D;  3AUG A;  3M7Q B;  2W8X A;  3FP6 I;  1KTH A;  1P2M B;  2UUY B;  4DTG K;  2KNT A;  3BTW I;  1TOC R;  1YLC B;  1TPA I;  3TGI I;  1ADZ A;  1T8O B;  4U32 X;  2FI3 I;  1ZR0 B;  1ZJD B;  4U30 W;  1T8M B;  3FP7 J;  1YLD B;  1KUN A;  1BRB I;  4Y0Z I;  2CA7 A;  5JB4 A;  2FTL I;  2M01 A;  1B0C A;  3P95 E;  4Y0Y I;  3OFW A;  2FI5 I;  1T7C B;  5JB7 A;  7PTI A;  3BTM I;  2J6D A;  3AUH A;  1OA5 5; 
#chains in the Genus database with same CATH topology
 1BUN B;  3BTQ I;  1TAW B;  1TFX C;  1BPI A;  3BTD I;  1OA6 5;  2TPI I;  4BD9 B;  3OTJ I;  8PTI A;  1EAW B;  2LFK A;  1DTX A;  1TAP A;  1YKT B;  1QLQ A;  1UUB A;  1G6X A;  1T8L B;  1AAP A;  1LD6 A;  3AUC A;  1BF0 A;  4BQD A;  2KCR A;  1BTH P;  2DDI A;  3BTT I;  3LDM A;  1IRH A;  4ISL B;  1BTI A;  1KNT A;  3UIR C;  1AAL A;  5JB5 A;  3UOU B;  3U1J E;  3LDI A;  3BTK I;  1P2N B;  4Y11 I;  1JV8 A;  2PTC I;  5C67 C;  3AUD A;  3BTF I;  1F7Z I;  4Y10 I;  3AUI A;  2KAI I;  3L3T E;  1P2Q B;  1P2J I;  1DTK A;  3TGJ I;  2TGP I;  2JOT A;  1CA0 D;  4BNR I;  1BIK A;  4ISO B;  1FAN A;  3L33 E;  1NAG A;  4WWY C;  1D0D B;  3D65 I;  1PIT A;  4WXV C;  3WNY A;  4ISN B;  1SHP A;  2ODY E;  1BRC I;  3P92 E;  1BZX I;  1T8N B;  3TGK I;  5JB6 A;  3TPI I;  1TCP A;  3BTH I;  2IJO I;  5PTI A;  3GYM I;  3FP8 I;  3BTG I;  1EJM B;  2R9P E;  3BYB A;  1BPT A;  2DDJ A;  6PTI A;  4PTI A;  4NTY B;  1LD5 A;  1UUA A;  1BHC A;  3AUE A;  2M99 A;  1FY8 I;  1FAK I;  3CI7 A;  1P2O B;  1P2K I;  1JV9 A;  2ZVX A;  3BTE I;  1F5R I;  1KIG I;  2FTM B;  4NTX B;  4NTW B;  3T62 D;  4DG4 C;  9PTI A;  1YC0 I;  1K6U A;  1JC6 A;  2UUX A;  2ZJX A;  2LFL A;  2HEX A;  1P2I I;  3LDJ A;  4TPI I;  1DEN A;  1BZ5 A;  1Y62 A;  3AUB A;  1MTN D;  2RA3 C;  1DEM A;  1D0D A;  2FI4 I;  1CO7 I;  1CBW D;  3AUG A;  3M7Q B;  2W8X A;  3FP6 I;  1KTH A;  1P2M B;  2UUY B;  4DTG K;  2KNT A;  3BTW I;  1TOC R;  1YLC B;  1TPA I;  3TGI I;  1ADZ A;  1T8O B;  4U32 X;  2FI3 I;  1ZR0 B;  1ZJD B;  4U30 W;  1T8M B;  3FP7 J;  1YLD B;  1KUN A;  1BRB I;  4Y0Z I;  2CA7 A;  5JB4 A;  2FTL I;  2M01 A;  1B0C A;  3P95 E;  4Y0Y I;  3OFW A;  2FI5 I;  1T7C B;  5JB7 A;  7PTI A;  3BTM I;  2J6D A;  3AUH A;  1OA5 5; 
#chains in the Genus database with same CATH homology
 1BUN B;  3BTQ I;  1TAW B;  1TFX C;  1BPI A;  3BTD I;  1OA6 5;  2TPI I;  4BD9 B;  3OTJ I;  8PTI A;  1EAW B;  2LFK A;  1DTX A;  1TAP A;  1YKT B;  1QLQ A;  1UUB A;  1G6X A;  1T8L B;  1AAP A;  1LD6 A;  3AUC A;  1BF0 A;  4BQD A;  2KCR A;  1BTH P;  2DDI A;  3BTT I;  3LDM A;  1IRH A;  4ISL B;  1BTI A;  1KNT A;  3UIR C;  1AAL A;  5JB5 A;  3UOU B;  3U1J E;  3LDI A;  3BTK I;  1P2N B;  4Y11 I;  1JV8 A;  2PTC I;  5C67 C;  3AUD A;  3BTF I;  1F7Z I;  4Y10 I;  3AUI A;  2KAI I;  3L3T E;  1P2Q B;  1P2J I;  1DTK A;  3TGJ I;  2TGP I;  2JOT A;  1CA0 D;  4BNR I;  1BIK A;  4ISO B;  1FAN A;  3L33 E;  1NAG A;  4WWY C;  1D0D B;  3D65 I;  1PIT A;  4WXV C;  3WNY A;  4ISN B;  1SHP A;  2ODY E;  1BRC I;  3P92 E;  1BZX I;  1T8N B;  3TGK I;  5JB6 A;  3TPI I;  1TCP A;  3BTH I;  2IJO I;  5PTI A;  3GYM I;  3FP8 I;  3BTG I;  1EJM B;  2R9P E;  3BYB A;  1BPT A;  2DDJ A;  6PTI A;  4PTI A;  4NTY B;  1LD5 A;  1UUA A;  1BHC A;  3AUE A;  2M99 A;  1FY8 I;  1FAK I;  3CI7 A;  1P2O B;  1P2K I;  1JV9 A;  2ZVX A;  3BTE I;  1F5R I;  1KIG I;  2FTM B;  4NTX B;  4NTW B;  3T62 D;  4DG4 C;  9PTI A;  1YC0 I;  1K6U A;  1JC6 A;  2UUX A;  2ZJX A;  2LFL A;  2HEX A;  1P2I I;  3LDJ A;  4TPI I;  1DEN A;  1BZ5 A;  1Y62 A;  3AUB A;  1MTN D;  2RA3 C;  1DEM A;  1D0D A;  2FI4 I;  1CO7 I;  1CBW D;  3AUG A;  3M7Q B;  2W8X A;  3FP6 I;  1KTH A;  1P2M B;  2UUY B;  4DTG K;  2KNT A;  3BTW I;  1TOC R;  1YLC B;  1TPA I;  3TGI I;  1ADZ A;  1T8O B;  4U32 X;  2FI3 I;  1ZR0 B;  1ZJD B;  4U30 W;  1T8M B;  3FP7 J;  1YLD B;  1KUN A;  1BRB I;  4Y0Z I;  2CA7 A;  5JB4 A;  2FTL I;  2M01 A;  1B0C A;  3P95 E;  4Y0Y I;  3OFW A;  2FI5 I;  1T7C B;  5JB7 A;  7PTI A;  3BTM I;  2J6D A;  3AUH A;  1OA5 5;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1ADZA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations