1DENA

Proteinase inhibitor homologues as potassium channel blockers
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
60
structure length
60
Chain Sequence
QPLRKLCILHRNPGRCYQKIPAFYYNQKKKQCEGFTWSGCGGNSNRFKTIEECRRTCIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Proteinase inhibitor homologues as potassium channel blockers.
pubmed doi rcsb
molecule tags Venom(potassium channel inhibitor)
source organism Dendroaspis polylepis polylepis
molecule keywords DENDROTOXIN I
total genus 5
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 1994-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1denA00
1K6UA 3TPII 1TFXC 2LFLA 3BTWI 1F7ZI 3L3TE 1Y62A 2CA7A 2KCRA 3AUGA 3BTTI 1BPIA 3D65I 4DTGK 7PTIA 5JB6A 2ODYE 1B0CA 1TCPA 4Y0ZI 2HEXA 5C67C 5JB4A 3BTQI 1TOCR 1IRHA 1YC0I 3BTDI 1SHPA 3L33E 3BTGI 1OA65 1T8OB 1P2MB 1BZ5A 3FP7J 1ADZA 3AUEA 1CO7I 4U32X 2PTCI 2UUYB 2R9PE 3OTJI 1KTHA 5PTIA 4PTIA 2JOTA 2M01A 2UUXA 1DEMA 1YLDB 1BTHP 3P92E 1TPAI 3U1JE 6PTIA 2TPII 2W8XA 1CBWD 3OFWA 2FI4I 1JC6A 1OA55 9PTIA 3AUCA 4NTWB 1D0DB 1BTIA 5JB5A 4BNRI 2FI5I 2IJOI 1LD5A 1T7CB 4BD9B 4BQDA 3LDMA 1TAPA 1DTXA 3BYBA 1PITA 3T62D 1UUAA 1ZJDB 1P2OB 3BTFI 3GYMI 1BRCI 4Y11I 3AUDA 1MTND 3FP6I 1BF0A 1YKTB 1ZR0B 4TPII 1EAWB 1CA0D 4NTYB 3WNYA 2FI3I 5JB7A 2FTMB 1FANA 3TGKI 1F5RI 1KUNA 1NAGA 1P2KI 3FP8I 4DG4C 1FY8I 2J6DA 3AUBA 3M7QB 1BPTA 1G6XA 2LFKA 2ZJXA 3UOUB 3TGJI 2M99A 3AUIA 1YLCB 3LDJA 3BTKI 2KAII 1P2QB 4ISOB 1BUNB 3BTHI 8PTIA 2TGPI 1KNTA 2DDIA 1QLQA 1T8MB 1AALA 4Y10I 1P2NB 1DTKA 3BTMI 4WXVC 4U30W 1BIKA 4Y0YI 1DENA 1BZXI 3BTEI 4NTXB 4WWYC 3CI7A 1BHCA 1AAPA 3LDIA 1P2II 2RA3C 1JV8A 1P2JI 1UUBA 2KNTA 1TAWB 1T8NB 1T8LB 2DDJA 1FAKI 2ZVXA 1BRBI 1LD6A 1D0DA 3UIRC 1KIGI 1EJMB 1JV9A 2FTLI 3AUHA 3P95E 4ISLB 3TGII 4ISNB
chains in the Genus database with same CATH superfamily
1K6UA 3TPII 1TFXC 2LFLA 3BTWI 1F7ZI 3L3TE 1Y62A 2CA7A 2KCRA 3AUGA 3BTTI 1BPIA 3D65I 4DTGK 7PTIA 5JB6A 2ODYE 1B0CA 1TCPA 4Y0ZI 2HEXA 5C67C 5JB4A 3BTQI 1TOCR 1IRHA 1YC0I 3BTDI 1SHPA 3L33E 3BTGI 1OA65 1T8OB 1P2MB 1BZ5A 3FP7J 1ADZA 3AUEA 1CO7I 4U32X 2PTCI 2UUYB 2R9PE 3OTJI 1KTHA 5PTIA 4PTIA 2JOTA 2M01A 2UUXA 1DEMA 1YLDB 1BTHP 3P92E 1TPAI 3U1JE 6PTIA 2TPII 2W8XA 1CBWD 3OFWA 2FI4I 1JC6A 1OA55 9PTIA 3AUCA 4NTWB 1D0DB 1BTIA 5JB5A 4BNRI 2FI5I 2IJOI 1LD5A 1T7CB 4BD9B 4BQDA 3LDMA 1TAPA 1DTXA 3BYBA 1PITA 3T62D 1UUAA 1ZJDB 1P2OB 3BTFI 3GYMI 1BRCI 4Y11I 3AUDA 1MTND 3FP6I 1BF0A 1YKTB 1ZR0B 4TPII 1EAWB 1CA0D 4NTYB 3WNYA 2FI3I 5JB7A 2FTMB 1FANA 3TGKI 1F5RI 1KUNA 1NAGA 1P2KI 3FP8I 4DG4C 1FY8I 2J6DA 3AUBA 3M7QB 1BPTA 1G6XA 2LFKA 2ZJXA 3UOUB 3TGJI 2M99A 3AUIA 1YLCB 3LDJA 3BTKI 2KAII 1P2QB 4ISOB 1BUNB 3BTHI 8PTIA 2TGPI 1KNTA 2DDIA 1QLQA 1T8MB 1AALA 4Y10I 1P2NB 1DTKA 3BTMI 4WXVC 4U30W 1BIKA 4Y0YI 1DENA 1BZXI 3BTEI 4NTXB 4WWYC 3CI7A 1BHCA 1AAPA 3LDIA 1P2II 2RA3C 1JV8A 1P2JI 1UUBA 2KNTA 1TAWB 1T8NB 1T8LB 2DDJA 1FAKI 2ZVXA 1BRBI 1LD6A 1D0DA 3UIRC 1KIGI 1EJMB 1JV9A 2FTLI 3AUHA 3P95E 4ISLB 3TGII 4ISNB
chains in the Genus database with same CATH topology
1K6UA 3TPII 1TFXC 2LFLA 3BTWI 1F7ZI 3L3TE 1Y62A 2CA7A 2KCRA 3AUGA 3BTTI 1BPIA 3D65I 4DTGK 7PTIA 5JB6A 2ODYE 1B0CA 1TCPA 4Y0ZI 2HEXA 5C67C 5JB4A 3BTQI 1TOCR 1IRHA 1YC0I 3BTDI 1SHPA 3L33E 3BTGI 1OA65 1T8OB 1P2MB 1BZ5A 3FP7J 1ADZA 3AUEA 1CO7I 4U32X 2PTCI 2UUYB 2R9PE 3OTJI 1KTHA 5PTIA 4PTIA 2JOTA 2M01A 2UUXA 1DEMA 1YLDB 1BTHP 3P92E 1TPAI 3U1JE 6PTIA 2TPII 2W8XA 1CBWD 3OFWA 2FI4I 1JC6A 1OA55 9PTIA 3AUCA 4NTWB 1D0DB 1BTIA 5JB5A 4BNRI 2FI5I 2IJOI 1LD5A 1T7CB 4BD9B 4BQDA 3LDMA 1TAPA 1DTXA 3BYBA 1PITA 3T62D 1UUAA 1ZJDB 1P2OB 3BTFI 3GYMI 1BRCI 4Y11I 3AUDA 1MTND 3FP6I 1BF0A 1YKTB 1ZR0B 4TPII 1EAWB 1CA0D 4NTYB 3WNYA 2FI3I 5JB7A 2FTMB 1FANA 3TGKI 1F5RI 1KUNA 1NAGA 1P2KI 3FP8I 4DG4C 1FY8I 2J6DA 3AUBA 3M7QB 1BPTA 1G6XA 2LFKA 2ZJXA 3UOUB 3TGJI 2M99A 3AUIA 1YLCB 3LDJA 3BTKI 2KAII 1P2QB 4ISOB 1BUNB 3BTHI 8PTIA 2TGPI 1KNTA 2DDIA 1QLQA 1T8MB 1AALA 4Y10I 1P2NB 1DTKA 3BTMI 4WXVC 4U30W 1BIKA 4Y0YI 1DENA 1BZXI 3BTEI 4NTXB 4WWYC 3CI7A 1BHCA 1AAPA 3LDIA 1P2II 2RA3C 1JV8A 1P2JI 1UUBA 2KNTA 1TAWB 1T8NB 1T8LB 2DDJA 1FAKI 2ZVXA 1BRBI 1LD6A 1D0DA 3UIRC 1KIGI 1EJMB 1JV9A 2FTLI 3AUHA 3P95E 4ISLB 3TGII 4ISNB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K6U A;  3TPI I;  1TFX C;  2LFL A;  3BTW I;  1F7Z I;  3L3T E;  1Y62 A;  2CA7 A;  2KCR A;  3AUG A;  3BTT I;  1BPI A;  3D65 I;  4DTG K;  7PTI A;  5JB6 A;  2ODY E;  1B0C A;  1TCP A;  4Y0Z I;  2HEX A;  5C67 C;  5JB4 A;  3BTQ I;  1TOC R;  1IRH A;  1YC0 I;  3BTD I;  1SHP A;  3L33 E;  3BTG I;  1OA6 5;  1T8O B;  1P2M B;  1BZ5 A;  3FP7 J;  1ADZ A;  3AUE A;  1CO7 I;  4U32 X;  2PTC I;  2UUY B;  2R9P E;  3OTJ I;  1KTH A;  5PTI A;  4PTI A;  2JOT A;  2M01 A;  2UUX A;  1DEM A;  1YLD B;  1BTH P;  3P92 E;  1TPA I;  3U1J E;  6PTI A;  2TPI I;  2W8X A;  1CBW D;  3OFW A;  2FI4 I;  1JC6 A;  1OA5 5;  9PTI A;  3AUC A;  4NTW B;  1D0D B;  1BTI A;  5JB5 A;  4BNR I;  2FI5 I;  2IJO I;  1LD5 A;  1T7C B;  4BD9 B;  4BQD A;  3LDM A;  1TAP A;  1DTX A;  3BYB A;  1PIT A;  3T62 D;  1UUA A;  1ZJD B;  1P2O B;  3BTF I;  3GYM I;  1BRC I;  4Y11 I;  3AUD A;  1MTN D;  3FP6 I;  1BF0 A;  1YKT B;  1ZR0 B;  4TPI I;  1EAW B;  1CA0 D;  4NTY B;  3WNY A;  2FI3 I;  5JB7 A;  2FTM B;  1FAN A;  3TGK I;  1F5R I;  1KUN A;  1NAG A;  1P2K I;  3FP8 I;  4DG4 C;  1FY8 I;  2J6D A;  3AUB A;  3M7Q B;  1BPT A;  1G6X A;  2LFK A;  2ZJX A;  3UOU B;  3TGJ I;  2M99 A;  3AUI A;  1YLC B;  3LDJ A;  3BTK I;  2KAI I;  1P2Q B;  4ISO B;  1BUN B;  3BTH I;  8PTI A;  2TGP I;  1KNT A;  2DDI A;  1QLQ A;  1T8M B;  1AAL A;  4Y10 I;  1P2N B;  1DTK A;  3BTM I;  4WXV C;  4U30 W;  1BIK A;  4Y0Y I;  1DEN A;  1BZX I;  3BTE I;  4NTX B;  4WWY C;  3CI7 A;  1BHC A;  1AAP A;  3LDI A;  1P2I I;  2RA3 C;  1JV8 A;  1P2J I;  1UUB A;  2KNT A;  1TAW B;  1T8N B;  1T8L B;  2DDJ A;  1FAK I;  2ZVX A;  1BRB I;  1LD6 A;  1D0D A;  3UIR C;  1KIG I;  1EJM B;  1JV9 A;  2FTL I;  3AUH A;  3P95 E;  4ISL B;  3TGI I;  4ISN B; 
#chains in the Genus database with same CATH topology
 1K6U A;  3TPI I;  1TFX C;  2LFL A;  3BTW I;  1F7Z I;  3L3T E;  1Y62 A;  2CA7 A;  2KCR A;  3AUG A;  3BTT I;  1BPI A;  3D65 I;  4DTG K;  7PTI A;  5JB6 A;  2ODY E;  1B0C A;  1TCP A;  4Y0Z I;  2HEX A;  5C67 C;  5JB4 A;  3BTQ I;  1TOC R;  1IRH A;  1YC0 I;  3BTD I;  1SHP A;  3L33 E;  3BTG I;  1OA6 5;  1T8O B;  1P2M B;  1BZ5 A;  3FP7 J;  1ADZ A;  3AUE A;  1CO7 I;  4U32 X;  2PTC I;  2UUY B;  2R9P E;  3OTJ I;  1KTH A;  5PTI A;  4PTI A;  2JOT A;  2M01 A;  2UUX A;  1DEM A;  1YLD B;  1BTH P;  3P92 E;  1TPA I;  3U1J E;  6PTI A;  2TPI I;  2W8X A;  1CBW D;  3OFW A;  2FI4 I;  1JC6 A;  1OA5 5;  9PTI A;  3AUC A;  4NTW B;  1D0D B;  1BTI A;  5JB5 A;  4BNR I;  2FI5 I;  2IJO I;  1LD5 A;  1T7C B;  4BD9 B;  4BQD A;  3LDM A;  1TAP A;  1DTX A;  3BYB A;  1PIT A;  3T62 D;  1UUA A;  1ZJD B;  1P2O B;  3BTF I;  3GYM I;  1BRC I;  4Y11 I;  3AUD A;  1MTN D;  3FP6 I;  1BF0 A;  1YKT B;  1ZR0 B;  4TPI I;  1EAW B;  1CA0 D;  4NTY B;  3WNY A;  2FI3 I;  5JB7 A;  2FTM B;  1FAN A;  3TGK I;  1F5R I;  1KUN A;  1NAG A;  1P2K I;  3FP8 I;  4DG4 C;  1FY8 I;  2J6D A;  3AUB A;  3M7Q B;  1BPT A;  1G6X A;  2LFK A;  2ZJX A;  3UOU B;  3TGJ I;  2M99 A;  3AUI A;  1YLC B;  3LDJ A;  3BTK I;  2KAI I;  1P2Q B;  4ISO B;  1BUN B;  3BTH I;  8PTI A;  2TGP I;  1KNT A;  2DDI A;  1QLQ A;  1T8M B;  1AAL A;  4Y10 I;  1P2N B;  1DTK A;  3BTM I;  4WXV C;  4U30 W;  1BIK A;  4Y0Y I;  1DEN A;  1BZX I;  3BTE I;  4NTX B;  4WWY C;  3CI7 A;  1BHC A;  1AAP A;  3LDI A;  1P2I I;  2RA3 C;  1JV8 A;  1P2J I;  1UUB A;  2KNT A;  1TAW B;  1T8N B;  1T8L B;  2DDJ A;  1FAK I;  2ZVX A;  1BRB I;  1LD6 A;  1D0D A;  3UIR C;  1KIG I;  1EJM B;  1JV9 A;  2FTL I;  3AUH A;  3P95 E;  4ISL B;  3TGI I;  4ISN B; 
#chains in the Genus database with same CATH homology
 1K6U A;  3TPI I;  1TFX C;  2LFL A;  3BTW I;  1F7Z I;  3L3T E;  1Y62 A;  2CA7 A;  2KCR A;  3AUG A;  3BTT I;  1BPI A;  3D65 I;  4DTG K;  7PTI A;  5JB6 A;  2ODY E;  1B0C A;  1TCP A;  4Y0Z I;  2HEX A;  5C67 C;  5JB4 A;  3BTQ I;  1TOC R;  1IRH A;  1YC0 I;  3BTD I;  1SHP A;  3L33 E;  3BTG I;  1OA6 5;  1T8O B;  1P2M B;  1BZ5 A;  3FP7 J;  1ADZ A;  3AUE A;  1CO7 I;  4U32 X;  2PTC I;  2UUY B;  2R9P E;  3OTJ I;  1KTH A;  5PTI A;  4PTI A;  2JOT A;  2M01 A;  2UUX A;  1DEM A;  1YLD B;  1BTH P;  3P92 E;  1TPA I;  3U1J E;  6PTI A;  2TPI I;  2W8X A;  1CBW D;  3OFW A;  2FI4 I;  1JC6 A;  1OA5 5;  9PTI A;  3AUC A;  4NTW B;  1D0D B;  1BTI A;  5JB5 A;  4BNR I;  2FI5 I;  2IJO I;  1LD5 A;  1T7C B;  4BD9 B;  4BQD A;  3LDM A;  1TAP A;  1DTX A;  3BYB A;  1PIT A;  3T62 D;  1UUA A;  1ZJD B;  1P2O B;  3BTF I;  3GYM I;  1BRC I;  4Y11 I;  3AUD A;  1MTN D;  3FP6 I;  1BF0 A;  1YKT B;  1ZR0 B;  4TPI I;  1EAW B;  1CA0 D;  4NTY B;  3WNY A;  2FI3 I;  5JB7 A;  2FTM B;  1FAN A;  3TGK I;  1F5R I;  1KUN A;  1NAG A;  1P2K I;  3FP8 I;  4DG4 C;  1FY8 I;  2J6D A;  3AUB A;  3M7Q B;  1BPT A;  1G6X A;  2LFK A;  2ZJX A;  3UOU B;  3TGJ I;  2M99 A;  3AUI A;  1YLC B;  3LDJ A;  3BTK I;  2KAI I;  1P2Q B;  4ISO B;  1BUN B;  3BTH I;  8PTI A;  2TGP I;  1KNT A;  2DDI A;  1QLQ A;  1T8M B;  1AAL A;  4Y10 I;  1P2N B;  1DTK A;  3BTM I;  4WXV C;  4U30 W;  1BIK A;  4Y0Y I;  1DEN A;  1BZX I;  3BTE I;  4NTX B;  4WWY C;  3CI7 A;  1BHC A;  1AAP A;  3LDI A;  1P2I I;  2RA3 C;  1JV8 A;  1P2J I;  1UUB A;  2KNT A;  1TAW B;  1T8N B;  1T8L B;  2DDJ A;  1FAK I;  2ZVX A;  1BRB I;  1LD6 A;  1D0D A;  3UIR C;  1KIG I;  1EJM B;  1JV9 A;  2FTL I;  3AUH A;  3P95 E;  4ISL B;  3TGI I;  4ISN B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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