1FANA

Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of f22a, y23a, n43g, and f45a
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNAKSAEDCMRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A.
pubmed rcsb
molecule tags Serine protease inhibitor
source organism Bos taurus
molecule keywords BOVINE PANCREATIC TRYPSIN INHIBITOR
total genus 8
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 1992-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1fanA00
3FP6I 3FP8I 3OFWA 4PTIA 2TPII 1P2OB 2FI3I 3P95E 1KIGI 4DG4C 2KNTA 2LFLA 3AUCA 1JV9A 1AAPA 7PTIA 4U30W 2LFKA 3L33E 2FI5I 1AALA 3AUBA 3GYMI 1FANA 3AUIA 5JB7A 3BTGI 1TOCR 2IJOI 3BYBA 1B0CA 3D65I 4ISNB 4Y0YI 5PTIA 2KAII 1D0DB 1UUAA 3TGII 1KNTA 2ODYE 1KTHA 2FTLI 2FTMB 3CI7A 1BPIA 3AUGA 3BTDI 4NTYB 3T62D 1TAWB 1BF0A 2ZJXA 4DTGK 1G6XA 1CBWD 1KUNA 1LD6A 1YKTB 4Y11I 1T8OB 1MTND 3TGJI 4BD9B 3BTWI 3LDJA 9PTIA 1ZR0B 3BTMI 1P2II 3LDMA 1F7ZI 4TPII 1P2JI 1YLDB 8PTIA 1ZJDB 1OA65 1PITA 1EAWB 3TPII 1BIKA 5JB6A 1Y62A 1BZXI 2DDIA 2KCRA 1YC0I 2PTCI 2HEXA 1TPAI 3TGKI 1T8NB 1T8MB 1P2QB 1TAPA 1DTXA 2UUXA 3BTKI 4Y0ZI 1LD5A 1JC6A 3WNYA 3AUDA 1CO7I 1DEMA 2W8XA 1DENA 3BTFI 3P92E 4U32X 4WWYC 4NTXB 2TGPI 3BTQI 1BUNB 3UOUB 2R9PE 2UUYB 3OTJI 3AUEA 1UUBA 1P2KI 1SHPA 5JB5A 2ZVXA 1TCPA 2RA3C 6PTIA 4WXVC 1YLCB 2M99A 2FI4I 1D0DA 1ADZA 1OA55 1NAGA 4Y10I 1BTHP 1BHCA 1BRBI 4ISLB 2M01A 4ISOB 1FY8I 1K6UA 1EJMB 3M7QB 3U1JE 1T8LB 1BRCI 1BZ5A 1P2NB 1BPTA 3BTEI 5C67C 1TFXC 1FAKI 4BNRI 3UIRC 1JV8A 1T7CB 1P2MB 4NTWB 1IRHA 1F5RI 1BTIA 1QLQA 3BTHI 3AUHA 2JOTA 1DTKA 2CA7A 1CA0D 2DDJA 2J6DA 3BTTI 3L3TE 3LDIA 5JB4A 4BQDA 3FP7J
chains in the Genus database with same CATH superfamily
3FP6I 3FP8I 3OFWA 4PTIA 2TPII 1P2OB 2FI3I 3P95E 1KIGI 4DG4C 2KNTA 2LFLA 3AUCA 1JV9A 1AAPA 7PTIA 4U30W 2LFKA 3L33E 2FI5I 1AALA 3AUBA 3GYMI 1FANA 3AUIA 5JB7A 3BTGI 1TOCR 2IJOI 3BYBA 1B0CA 3D65I 4ISNB 4Y0YI 5PTIA 2KAII 1D0DB 1UUAA 3TGII 1KNTA 2ODYE 1KTHA 2FTLI 2FTMB 3CI7A 1BPIA 3AUGA 3BTDI 4NTYB 3T62D 1TAWB 1BF0A 2ZJXA 4DTGK 1G6XA 1CBWD 1KUNA 1LD6A 1YKTB 4Y11I 1T8OB 1MTND 3TGJI 4BD9B 3BTWI 3LDJA 9PTIA 1ZR0B 3BTMI 1P2II 3LDMA 1F7ZI 4TPII 1P2JI 1YLDB 8PTIA 1ZJDB 1OA65 1PITA 1EAWB 3TPII 1BIKA 5JB6A 1Y62A 1BZXI 2DDIA 2KCRA 1YC0I 2PTCI 2HEXA 1TPAI 3TGKI 1T8NB 1T8MB 1P2QB 1TAPA 1DTXA 2UUXA 3BTKI 4Y0ZI 1LD5A 1JC6A 3WNYA 3AUDA 1CO7I 1DEMA 2W8XA 1DENA 3BTFI 3P92E 4U32X 4WWYC 4NTXB 2TGPI 3BTQI 1BUNB 3UOUB 2R9PE 2UUYB 3OTJI 3AUEA 1UUBA 1P2KI 1SHPA 5JB5A 2ZVXA 1TCPA 2RA3C 6PTIA 4WXVC 1YLCB 2M99A 2FI4I 1D0DA 1ADZA 1OA55 1NAGA 4Y10I 1BTHP 1BHCA 1BRBI 4ISLB 2M01A 4ISOB 1FY8I 1K6UA 1EJMB 3M7QB 3U1JE 1T8LB 1BRCI 1BZ5A 1P2NB 1BPTA 3BTEI 5C67C 1TFXC 1FAKI 4BNRI 3UIRC 1JV8A 1T7CB 1P2MB 4NTWB 1IRHA 1F5RI 1BTIA 1QLQA 3BTHI 3AUHA 2JOTA 1DTKA 2CA7A 1CA0D 2DDJA 2J6DA 3BTTI 3L3TE 3LDIA 5JB4A 4BQDA 3FP7J
chains in the Genus database with same CATH topology
3FP6I 3FP8I 3OFWA 4PTIA 2TPII 1P2OB 2FI3I 3P95E 1KIGI 4DG4C 2KNTA 2LFLA 3AUCA 1JV9A 1AAPA 7PTIA 4U30W 2LFKA 3L33E 2FI5I 1AALA 3AUBA 3GYMI 1FANA 3AUIA 5JB7A 3BTGI 1TOCR 2IJOI 3BYBA 1B0CA 3D65I 4ISNB 4Y0YI 5PTIA 2KAII 1D0DB 1UUAA 3TGII 1KNTA 2ODYE 1KTHA 2FTLI 2FTMB 3CI7A 1BPIA 3AUGA 3BTDI 4NTYB 3T62D 1TAWB 1BF0A 2ZJXA 4DTGK 1G6XA 1CBWD 1KUNA 1LD6A 1YKTB 4Y11I 1T8OB 1MTND 3TGJI 4BD9B 3BTWI 3LDJA 9PTIA 1ZR0B 3BTMI 1P2II 3LDMA 1F7ZI 4TPII 1P2JI 1YLDB 8PTIA 1ZJDB 1OA65 1PITA 1EAWB 3TPII 1BIKA 5JB6A 1Y62A 1BZXI 2DDIA 2KCRA 1YC0I 2PTCI 2HEXA 1TPAI 3TGKI 1T8NB 1T8MB 1P2QB 1TAPA 1DTXA 2UUXA 3BTKI 4Y0ZI 1LD5A 1JC6A 3WNYA 3AUDA 1CO7I 1DEMA 2W8XA 1DENA 3BTFI 3P92E 4U32X 4WWYC 4NTXB 2TGPI 3BTQI 1BUNB 3UOUB 2R9PE 2UUYB 3OTJI 3AUEA 1UUBA 1P2KI 1SHPA 5JB5A 2ZVXA 1TCPA 2RA3C 6PTIA 4WXVC 1YLCB 2M99A 2FI4I 1D0DA 1ADZA 1OA55 1NAGA 4Y10I 1BTHP 1BHCA 1BRBI 4ISLB 2M01A 4ISOB 1FY8I 1K6UA 1EJMB 3M7QB 3U1JE 1T8LB 1BRCI 1BZ5A 1P2NB 1BPTA 3BTEI 5C67C 1TFXC 1FAKI 4BNRI 3UIRC 1JV8A 1T7CB 1P2MB 4NTWB 1IRHA 1F5RI 1BTIA 1QLQA 3BTHI 3AUHA 2JOTA 1DTKA 2CA7A 1CA0D 2DDJA 2J6DA 3BTTI 3L3TE 3LDIA 5JB4A 4BQDA 3FP7J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FP6 I;  3FP8 I;  3OFW A;  4PTI A;  2TPI I;  1P2O B;  2FI3 I;  3P95 E;  1KIG I;  4DG4 C;  2KNT A;  2LFL A;  3AUC A;  1JV9 A;  1AAP A;  7PTI A;  4U30 W;  2LFK A;  3L33 E;  2FI5 I;  1AAL A;  3AUB A;  3GYM I;  1FAN A;  3AUI A;  5JB7 A;  3BTG I;  1TOC R;  2IJO I;  3BYB A;  1B0C A;  3D65 I;  4ISN B;  4Y0Y I;  5PTI A;  2KAI I;  1D0D B;  1UUA A;  3TGI I;  1KNT A;  2ODY E;  1KTH A;  2FTL I;  2FTM B;  3CI7 A;  1BPI A;  3AUG A;  3BTD I;  4NTY B;  3T62 D;  1TAW B;  1BF0 A;  2ZJX A;  4DTG K;  1G6X A;  1CBW D;  1KUN A;  1LD6 A;  1YKT B;  4Y11 I;  1T8O B;  1MTN D;  3TGJ I;  4BD9 B;  3BTW I;  3LDJ A;  9PTI A;  1ZR0 B;  3BTM I;  1P2I I;  3LDM A;  1F7Z I;  4TPI I;  1P2J I;  1YLD B;  8PTI A;  1ZJD B;  1OA6 5;  1PIT A;  1EAW B;  3TPI I;  1BIK A;  5JB6 A;  1Y62 A;  1BZX I;  2DDI A;  2KCR A;  1YC0 I;  2PTC I;  2HEX A;  1TPA I;  3TGK I;  1T8N B;  1T8M B;  1P2Q B;  1TAP A;  1DTX A;  2UUX A;  3BTK I;  4Y0Z I;  1LD5 A;  1JC6 A;  3WNY A;  3AUD A;  1CO7 I;  1DEM A;  2W8X A;  1DEN A;  3BTF I;  3P92 E;  4U32 X;  4WWY C;  4NTX B;  2TGP I;  3BTQ I;  1BUN B;  3UOU B;  2R9P E;  2UUY B;  3OTJ I;  3AUE A;  1UUB A;  1P2K I;  1SHP A;  5JB5 A;  2ZVX A;  1TCP A;  2RA3 C;  6PTI A;  4WXV C;  1YLC B;  2M99 A;  2FI4 I;  1D0D A;  1ADZ A;  1OA5 5;  1NAG A;  4Y10 I;  1BTH P;  1BHC A;  1BRB I;  4ISL B;  2M01 A;  4ISO B;  1FY8 I;  1K6U A;  1EJM B;  3M7Q B;  3U1J E;  1T8L B;  1BRC I;  1BZ5 A;  1P2N B;  1BPT A;  3BTE I;  5C67 C;  1TFX C;  1FAK I;  4BNR I;  3UIR C;  1JV8 A;  1T7C B;  1P2M B;  4NTW B;  1IRH A;  1F5R I;  1BTI A;  1QLQ A;  3BTH I;  3AUH A;  2JOT A;  1DTK A;  2CA7 A;  1CA0 D;  2DDJ A;  2J6D A;  3BTT I;  3L3T E;  3LDI A;  5JB4 A;  4BQD A;  3FP7 J; 
#chains in the Genus database with same CATH topology
 3FP6 I;  3FP8 I;  3OFW A;  4PTI A;  2TPI I;  1P2O B;  2FI3 I;  3P95 E;  1KIG I;  4DG4 C;  2KNT A;  2LFL A;  3AUC A;  1JV9 A;  1AAP A;  7PTI A;  4U30 W;  2LFK A;  3L33 E;  2FI5 I;  1AAL A;  3AUB A;  3GYM I;  1FAN A;  3AUI A;  5JB7 A;  3BTG I;  1TOC R;  2IJO I;  3BYB A;  1B0C A;  3D65 I;  4ISN B;  4Y0Y I;  5PTI A;  2KAI I;  1D0D B;  1UUA A;  3TGI I;  1KNT A;  2ODY E;  1KTH A;  2FTL I;  2FTM B;  3CI7 A;  1BPI A;  3AUG A;  3BTD I;  4NTY B;  3T62 D;  1TAW B;  1BF0 A;  2ZJX A;  4DTG K;  1G6X A;  1CBW D;  1KUN A;  1LD6 A;  1YKT B;  4Y11 I;  1T8O B;  1MTN D;  3TGJ I;  4BD9 B;  3BTW I;  3LDJ A;  9PTI A;  1ZR0 B;  3BTM I;  1P2I I;  3LDM A;  1F7Z I;  4TPI I;  1P2J I;  1YLD B;  8PTI A;  1ZJD B;  1OA6 5;  1PIT A;  1EAW B;  3TPI I;  1BIK A;  5JB6 A;  1Y62 A;  1BZX I;  2DDI A;  2KCR A;  1YC0 I;  2PTC I;  2HEX A;  1TPA I;  3TGK I;  1T8N B;  1T8M B;  1P2Q B;  1TAP A;  1DTX A;  2UUX A;  3BTK I;  4Y0Z I;  1LD5 A;  1JC6 A;  3WNY A;  3AUD A;  1CO7 I;  1DEM A;  2W8X A;  1DEN A;  3BTF I;  3P92 E;  4U32 X;  4WWY C;  4NTX B;  2TGP I;  3BTQ I;  1BUN B;  3UOU B;  2R9P E;  2UUY B;  3OTJ I;  3AUE A;  1UUB A;  1P2K I;  1SHP A;  5JB5 A;  2ZVX A;  1TCP A;  2RA3 C;  6PTI A;  4WXV C;  1YLC B;  2M99 A;  2FI4 I;  1D0D A;  1ADZ A;  1OA5 5;  1NAG A;  4Y10 I;  1BTH P;  1BHC A;  1BRB I;  4ISL B;  2M01 A;  4ISO B;  1FY8 I;  1K6U A;  1EJM B;  3M7Q B;  3U1J E;  1T8L B;  1BRC I;  1BZ5 A;  1P2N B;  1BPT A;  3BTE I;  5C67 C;  1TFX C;  1FAK I;  4BNR I;  3UIR C;  1JV8 A;  1T7C B;  1P2M B;  4NTW B;  1IRH A;  1F5R I;  1BTI A;  1QLQ A;  3BTH I;  3AUH A;  2JOT A;  1DTK A;  2CA7 A;  1CA0 D;  2DDJ A;  2J6D A;  3BTT I;  3L3T E;  3LDI A;  5JB4 A;  4BQD A;  3FP7 J; 
#chains in the Genus database with same CATH homology
 3FP6 I;  3FP8 I;  3OFW A;  4PTI A;  2TPI I;  1P2O B;  2FI3 I;  3P95 E;  1KIG I;  4DG4 C;  2KNT A;  2LFL A;  3AUC A;  1JV9 A;  1AAP A;  7PTI A;  4U30 W;  2LFK A;  3L33 E;  2FI5 I;  1AAL A;  3AUB A;  3GYM I;  1FAN A;  3AUI A;  5JB7 A;  3BTG I;  1TOC R;  2IJO I;  3BYB A;  1B0C A;  3D65 I;  4ISN B;  4Y0Y I;  5PTI A;  2KAI I;  1D0D B;  1UUA A;  3TGI I;  1KNT A;  2ODY E;  1KTH A;  2FTL I;  2FTM B;  3CI7 A;  1BPI A;  3AUG A;  3BTD I;  4NTY B;  3T62 D;  1TAW B;  1BF0 A;  2ZJX A;  4DTG K;  1G6X A;  1CBW D;  1KUN A;  1LD6 A;  1YKT B;  4Y11 I;  1T8O B;  1MTN D;  3TGJ I;  4BD9 B;  3BTW I;  3LDJ A;  9PTI A;  1ZR0 B;  3BTM I;  1P2I I;  3LDM A;  1F7Z I;  4TPI I;  1P2J I;  1YLD B;  8PTI A;  1ZJD B;  1OA6 5;  1PIT A;  1EAW B;  3TPI I;  1BIK A;  5JB6 A;  1Y62 A;  1BZX I;  2DDI A;  2KCR A;  1YC0 I;  2PTC I;  2HEX A;  1TPA I;  3TGK I;  1T8N B;  1T8M B;  1P2Q B;  1TAP A;  1DTX A;  2UUX A;  3BTK I;  4Y0Z I;  1LD5 A;  1JC6 A;  3WNY A;  3AUD A;  1CO7 I;  1DEM A;  2W8X A;  1DEN A;  3BTF I;  3P92 E;  4U32 X;  4WWY C;  4NTX B;  2TGP I;  3BTQ I;  1BUN B;  3UOU B;  2R9P E;  2UUY B;  3OTJ I;  3AUE A;  1UUB A;  1P2K I;  1SHP A;  5JB5 A;  2ZVX A;  1TCP A;  2RA3 C;  6PTI A;  4WXV C;  1YLC B;  2M99 A;  2FI4 I;  1D0D A;  1ADZ A;  1OA5 5;  1NAG A;  4Y10 I;  1BTH P;  1BHC A;  1BRB I;  4ISL B;  2M01 A;  4ISO B;  1FY8 I;  1K6U A;  1EJM B;  3M7Q B;  3U1J E;  1T8L B;  1BRC I;  1BZ5 A;  1P2N B;  1BPT A;  3BTE I;  5C67 C;  1TFX C;  1FAK I;  4BNR I;  3UIR C;  1JV8 A;  1T7C B;  1P2M B;  4NTW B;  1IRH A;  1F5R I;  1BTI A;  1QLQ A;  3BTH I;  3AUH A;  2JOT A;  1DTK A;  2CA7 A;  1CA0 D;  2DDJ A;  2J6D A;  3BTT I;  3L3T E;  3LDI A;  5JB4 A;  4BQD A;  3FP7 J; 
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