1G6XA

Ultra high resolution structure of bovine pancreatic trypsin inhibitor (bpti) mutant with altered binding loop sequence
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYAGACRARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCLRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ultrahigh-resolution structure of a BPTI mutant.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Bos taurus
molecule keywords PANCREATIC TRYPSIN INHIBITOR
total genus 8
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2000-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1g6xA00
1CO7I 2FI3I 2KCRA 4ISOB 1TAPA 1BPTA 1YC0I 1OA65 9PTIA 1FAKI 3UOUB 4NTWB 1PITA 2KNTA 1YLDB 3BTMI 1TPAI 1CBWD 1KNTA 1UUAA 3AUGA 3U1JE 2FTLI 1D0DB 4U32X 2W8XA 4WWYC 7PTIA 1JV8A 4NTXB 1FY8I 1P2II 1QLQA 2CA7A 6PTIA 3AUEA 3L3TE 1SHPA 2M01A 1IRHA 1FANA 1G6XA 2PTCI 1JC6A 1T8MB 1BZXI 2HEXA 1LD5A 4ISNB 4Y0YI 3BYBA 1EAWB 2M99A 3FP7J 1TAWB 3TGKI 3LDMA 1P2NB 3LDJA 3D65I 3P92E 5JB4A 2DDIA 3T62D 1BRBI 3TPII 5JB5A 1P2JI 3M7QB 1DEMA 1YKTB 5JB6A 1BIKA 1F7ZI 3BTDI 4BD9B 1P2KI 4DTGK 1BTHP 1OA55 1TFXC 2FI4I 1EJMB 3AUCA 2ZVXA 1Y62A 3LDIA 2ZJXA 3FP6I 2UUYB 1P2MB 3L33E 1NAGA 1BHCA 3BTTI 3OTJI 2IJOI 2TGPI 1AAPA 2FTMB 3TGJI 4DG4C 8PTIA 4BQDA 1DTKA 3AUBA 2DDJA 4TPII 4BNRI 1ZR0B 5PTIA 3BTWI 1D0DA 4Y10I 1BZ5A 1P2QB 4WXVC 1LD6A 4Y11I 5C67C 1KUNA 1T8OB 1DTXA 3BTEI 1BRCI 2UUXA 4PTIA 1ZJDB 1AALA 1TOCR 1BUNB 3P95E 1T7CB 1B0CA 3BTQI 1BTIA 1BF0A 1JV9A 2J6DA 1MTND 1UUBA 1K6UA 3OFWA 1P2OB 3BTFI 1TCPA 1BPIA 2ODYE 2FI5I 2KAII 4U30W 3BTGI 4ISLB 2TPII 1T8NB 1ADZA 2R9PE 1YLCB 3BTHI 3WNYA 3AUDA 3BTKI 2LFLA 3GYMI 1KTHA 1KIGI 1F5RI 3TGII 2LFKA 2RA3C 4Y0ZI 1T8LB 1DENA 4NTYB 3FP8I 3UIRC 2JOTA 3AUIA 5JB7A 1CA0D 3AUHA 3CI7A
chains in the Genus database with same CATH superfamily
1CO7I 2FI3I 2KCRA 4ISOB 1TAPA 1BPTA 1YC0I 1OA65 9PTIA 1FAKI 3UOUB 4NTWB 1PITA 2KNTA 1YLDB 3BTMI 1TPAI 1CBWD 1KNTA 1UUAA 3AUGA 3U1JE 2FTLI 1D0DB 4U32X 2W8XA 4WWYC 7PTIA 1JV8A 4NTXB 1FY8I 1P2II 1QLQA 2CA7A 6PTIA 3AUEA 3L3TE 1SHPA 2M01A 1IRHA 1FANA 1G6XA 2PTCI 1JC6A 1T8MB 1BZXI 2HEXA 1LD5A 4ISNB 4Y0YI 3BYBA 1EAWB 2M99A 3FP7J 1TAWB 3TGKI 3LDMA 1P2NB 3LDJA 3D65I 3P92E 5JB4A 2DDIA 3T62D 1BRBI 3TPII 5JB5A 1P2JI 3M7QB 1DEMA 1YKTB 5JB6A 1BIKA 1F7ZI 3BTDI 4BD9B 1P2KI 4DTGK 1BTHP 1OA55 1TFXC 2FI4I 1EJMB 3AUCA 2ZVXA 1Y62A 3LDIA 2ZJXA 3FP6I 2UUYB 1P2MB 3L33E 1NAGA 1BHCA 3BTTI 3OTJI 2IJOI 2TGPI 1AAPA 2FTMB 3TGJI 4DG4C 8PTIA 4BQDA 1DTKA 3AUBA 2DDJA 4TPII 4BNRI 1ZR0B 5PTIA 3BTWI 1D0DA 4Y10I 1BZ5A 1P2QB 4WXVC 1LD6A 4Y11I 5C67C 1KUNA 1T8OB 1DTXA 3BTEI 1BRCI 2UUXA 4PTIA 1ZJDB 1AALA 1TOCR 1BUNB 3P95E 1T7CB 1B0CA 3BTQI 1BTIA 1BF0A 1JV9A 2J6DA 1MTND 1UUBA 1K6UA 3OFWA 1P2OB 3BTFI 1TCPA 1BPIA 2ODYE 2FI5I 2KAII 4U30W 3BTGI 4ISLB 2TPII 1T8NB 1ADZA 2R9PE 1YLCB 3BTHI 3WNYA 3AUDA 3BTKI 2LFLA 3GYMI 1KTHA 1KIGI 1F5RI 3TGII 2LFKA 2RA3C 4Y0ZI 1T8LB 1DENA 4NTYB 3FP8I 3UIRC 2JOTA 3AUIA 5JB7A 1CA0D 3AUHA 3CI7A
chains in the Genus database with same CATH topology
1CO7I 2FI3I 2KCRA 4ISOB 1TAPA 1BPTA 1YC0I 1OA65 9PTIA 1FAKI 3UOUB 4NTWB 1PITA 2KNTA 1YLDB 3BTMI 1TPAI 1CBWD 1KNTA 1UUAA 3AUGA 3U1JE 2FTLI 1D0DB 4U32X 2W8XA 4WWYC 7PTIA 1JV8A 4NTXB 1FY8I 1P2II 1QLQA 2CA7A 6PTIA 3AUEA 3L3TE 1SHPA 2M01A 1IRHA 1FANA 1G6XA 2PTCI 1JC6A 1T8MB 1BZXI 2HEXA 1LD5A 4ISNB 4Y0YI 3BYBA 1EAWB 2M99A 3FP7J 1TAWB 3TGKI 3LDMA 1P2NB 3LDJA 3D65I 3P92E 5JB4A 2DDIA 3T62D 1BRBI 3TPII 5JB5A 1P2JI 3M7QB 1DEMA 1YKTB 5JB6A 1BIKA 1F7ZI 3BTDI 4BD9B 1P2KI 4DTGK 1BTHP 1OA55 1TFXC 2FI4I 1EJMB 3AUCA 2ZVXA 1Y62A 3LDIA 2ZJXA 3FP6I 2UUYB 1P2MB 3L33E 1NAGA 1BHCA 3BTTI 3OTJI 2IJOI 2TGPI 1AAPA 2FTMB 3TGJI 4DG4C 8PTIA 4BQDA 1DTKA 3AUBA 2DDJA 4TPII 4BNRI 1ZR0B 5PTIA 3BTWI 1D0DA 4Y10I 1BZ5A 1P2QB 4WXVC 1LD6A 4Y11I 5C67C 1KUNA 1T8OB 1DTXA 3BTEI 1BRCI 2UUXA 4PTIA 1ZJDB 1AALA 1TOCR 1BUNB 3P95E 1T7CB 1B0CA 3BTQI 1BTIA 1BF0A 1JV9A 2J6DA 1MTND 1UUBA 1K6UA 3OFWA 1P2OB 3BTFI 1TCPA 1BPIA 2ODYE 2FI5I 2KAII 4U30W 3BTGI 4ISLB 2TPII 1T8NB 1ADZA 2R9PE 1YLCB 3BTHI 3WNYA 3AUDA 3BTKI 2LFLA 3GYMI 1KTHA 1KIGI 1F5RI 3TGII 2LFKA 2RA3C 4Y0ZI 1T8LB 1DENA 4NTYB 3FP8I 3UIRC 2JOTA 3AUIA 5JB7A 1CA0D 3AUHA 3CI7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CO7 I;  2FI3 I;  2KCR A;  4ISO B;  1TAP A;  1BPT A;  1YC0 I;  1OA6 5;  9PTI A;  1FAK I;  3UOU B;  4NTW B;  1PIT A;  2KNT A;  1YLD B;  3BTM I;  1TPA I;  1CBW D;  1KNT A;  1UUA A;  3AUG A;  3U1J E;  2FTL I;  1D0D B;  4U32 X;  2W8X A;  4WWY C;  7PTI A;  1JV8 A;  4NTX B;  1FY8 I;  1P2I I;  1QLQ A;  2CA7 A;  6PTI A;  3AUE A;  3L3T E;  1SHP A;  2M01 A;  1IRH A;  1FAN A;  1G6X A;  2PTC I;  1JC6 A;  1T8M B;  1BZX I;  2HEX A;  1LD5 A;  4ISN B;  4Y0Y I;  3BYB A;  1EAW B;  2M99 A;  3FP7 J;  1TAW B;  3TGK I;  3LDM A;  1P2N B;  3LDJ A;  3D65 I;  3P92 E;  5JB4 A;  2DDI A;  3T62 D;  1BRB I;  3TPI I;  5JB5 A;  1P2J I;  3M7Q B;  1DEM A;  1YKT B;  5JB6 A;  1BIK A;  1F7Z I;  3BTD I;  4BD9 B;  1P2K I;  4DTG K;  1BTH P;  1OA5 5;  1TFX C;  2FI4 I;  1EJM B;  3AUC A;  2ZVX A;  1Y62 A;  3LDI A;  2ZJX A;  3FP6 I;  2UUY B;  1P2M B;  3L33 E;  1NAG A;  1BHC A;  3BTT I;  3OTJ I;  2IJO I;  2TGP I;  1AAP A;  2FTM B;  3TGJ I;  4DG4 C;  8PTI A;  4BQD A;  1DTK A;  3AUB A;  2DDJ A;  4TPI I;  4BNR I;  1ZR0 B;  5PTI A;  3BTW I;  1D0D A;  4Y10 I;  1BZ5 A;  1P2Q B;  4WXV C;  1LD6 A;  4Y11 I;  5C67 C;  1KUN A;  1T8O B;  1DTX A;  3BTE I;  1BRC I;  2UUX A;  4PTI A;  1ZJD B;  1AAL A;  1TOC R;  1BUN B;  3P95 E;  1T7C B;  1B0C A;  3BTQ I;  1BTI A;  1BF0 A;  1JV9 A;  2J6D A;  1MTN D;  1UUB A;  1K6U A;  3OFW A;  1P2O B;  3BTF I;  1TCP A;  1BPI A;  2ODY E;  2FI5 I;  2KAI I;  4U30 W;  3BTG I;  4ISL B;  2TPI I;  1T8N B;  1ADZ A;  2R9P E;  1YLC B;  3BTH I;  3WNY A;  3AUD A;  3BTK I;  2LFL A;  3GYM I;  1KTH A;  1KIG I;  1F5R I;  3TGI I;  2LFK A;  2RA3 C;  4Y0Z I;  1T8L B;  1DEN A;  4NTY B;  3FP8 I;  3UIR C;  2JOT A;  3AUI A;  5JB7 A;  1CA0 D;  3AUH A;  3CI7 A; 
#chains in the Genus database with same CATH topology
 1CO7 I;  2FI3 I;  2KCR A;  4ISO B;  1TAP A;  1BPT A;  1YC0 I;  1OA6 5;  9PTI A;  1FAK I;  3UOU B;  4NTW B;  1PIT A;  2KNT A;  1YLD B;  3BTM I;  1TPA I;  1CBW D;  1KNT A;  1UUA A;  3AUG A;  3U1J E;  2FTL I;  1D0D B;  4U32 X;  2W8X A;  4WWY C;  7PTI A;  1JV8 A;  4NTX B;  1FY8 I;  1P2I I;  1QLQ A;  2CA7 A;  6PTI A;  3AUE A;  3L3T E;  1SHP A;  2M01 A;  1IRH A;  1FAN A;  1G6X A;  2PTC I;  1JC6 A;  1T8M B;  1BZX I;  2HEX A;  1LD5 A;  4ISN B;  4Y0Y I;  3BYB A;  1EAW B;  2M99 A;  3FP7 J;  1TAW B;  3TGK I;  3LDM A;  1P2N B;  3LDJ A;  3D65 I;  3P92 E;  5JB4 A;  2DDI A;  3T62 D;  1BRB I;  3TPI I;  5JB5 A;  1P2J I;  3M7Q B;  1DEM A;  1YKT B;  5JB6 A;  1BIK A;  1F7Z I;  3BTD I;  4BD9 B;  1P2K I;  4DTG K;  1BTH P;  1OA5 5;  1TFX C;  2FI4 I;  1EJM B;  3AUC A;  2ZVX A;  1Y62 A;  3LDI A;  2ZJX A;  3FP6 I;  2UUY B;  1P2M B;  3L33 E;  1NAG A;  1BHC A;  3BTT I;  3OTJ I;  2IJO I;  2TGP I;  1AAP A;  2FTM B;  3TGJ I;  4DG4 C;  8PTI A;  4BQD A;  1DTK A;  3AUB A;  2DDJ A;  4TPI I;  4BNR I;  1ZR0 B;  5PTI A;  3BTW I;  1D0D A;  4Y10 I;  1BZ5 A;  1P2Q B;  4WXV C;  1LD6 A;  4Y11 I;  5C67 C;  1KUN A;  1T8O B;  1DTX A;  3BTE I;  1BRC I;  2UUX A;  4PTI A;  1ZJD B;  1AAL A;  1TOC R;  1BUN B;  3P95 E;  1T7C B;  1B0C A;  3BTQ I;  1BTI A;  1BF0 A;  1JV9 A;  2J6D A;  1MTN D;  1UUB A;  1K6U A;  3OFW A;  1P2O B;  3BTF I;  1TCP A;  1BPI A;  2ODY E;  2FI5 I;  2KAI I;  4U30 W;  3BTG I;  4ISL B;  2TPI I;  1T8N B;  1ADZ A;  2R9P E;  1YLC B;  3BTH I;  3WNY A;  3AUD A;  3BTK I;  2LFL A;  3GYM I;  1KTH A;  1KIG I;  1F5R I;  3TGI I;  2LFK A;  2RA3 C;  4Y0Z I;  1T8L B;  1DEN A;  4NTY B;  3FP8 I;  3UIR C;  2JOT A;  3AUI A;  5JB7 A;  1CA0 D;  3AUH A;  3CI7 A; 
#chains in the Genus database with same CATH homology
 1CO7 I;  2FI3 I;  2KCR A;  4ISO B;  1TAP A;  1BPT A;  1YC0 I;  1OA6 5;  9PTI A;  1FAK I;  3UOU B;  4NTW B;  1PIT A;  2KNT A;  1YLD B;  3BTM I;  1TPA I;  1CBW D;  1KNT A;  1UUA A;  3AUG A;  3U1J E;  2FTL I;  1D0D B;  4U32 X;  2W8X A;  4WWY C;  7PTI A;  1JV8 A;  4NTX B;  1FY8 I;  1P2I I;  1QLQ A;  2CA7 A;  6PTI A;  3AUE A;  3L3T E;  1SHP A;  2M01 A;  1IRH A;  1FAN A;  1G6X A;  2PTC I;  1JC6 A;  1T8M B;  1BZX I;  2HEX A;  1LD5 A;  4ISN B;  4Y0Y I;  3BYB A;  1EAW B;  2M99 A;  3FP7 J;  1TAW B;  3TGK I;  3LDM A;  1P2N B;  3LDJ A;  3D65 I;  3P92 E;  5JB4 A;  2DDI A;  3T62 D;  1BRB I;  3TPI I;  5JB5 A;  1P2J I;  3M7Q B;  1DEM A;  1YKT B;  5JB6 A;  1BIK A;  1F7Z I;  3BTD I;  4BD9 B;  1P2K I;  4DTG K;  1BTH P;  1OA5 5;  1TFX C;  2FI4 I;  1EJM B;  3AUC A;  2ZVX A;  1Y62 A;  3LDI A;  2ZJX A;  3FP6 I;  2UUY B;  1P2M B;  3L33 E;  1NAG A;  1BHC A;  3BTT I;  3OTJ I;  2IJO I;  2TGP I;  1AAP A;  2FTM B;  3TGJ I;  4DG4 C;  8PTI A;  4BQD A;  1DTK A;  3AUB A;  2DDJ A;  4TPI I;  4BNR I;  1ZR0 B;  5PTI A;  3BTW I;  1D0D A;  4Y10 I;  1BZ5 A;  1P2Q B;  4WXV C;  1LD6 A;  4Y11 I;  5C67 C;  1KUN A;  1T8O B;  1DTX A;  3BTE I;  1BRC I;  2UUX A;  4PTI A;  1ZJD B;  1AAL A;  1TOC R;  1BUN B;  3P95 E;  1T7C B;  1B0C A;  3BTQ I;  1BTI A;  1BF0 A;  1JV9 A;  2J6D A;  1MTN D;  1UUB A;  1K6U A;  3OFW A;  1P2O B;  3BTF I;  1TCP A;  1BPI A;  2ODY E;  2FI5 I;  2KAI I;  4U30 W;  3BTG I;  4ISL B;  2TPI I;  1T8N B;  1ADZ A;  2R9P E;  1YLC B;  3BTH I;  3WNY A;  3AUD A;  3BTK I;  2LFL A;  3GYM I;  1KTH A;  1KIG I;  1F5R I;  3TGI I;  2LFK A;  2RA3 C;  4Y0Z I;  1T8L B;  1DEN A;  4NTY B;  3FP8 I;  3UIR C;  2JOT A;  3AUI A;  5JB7 A;  1CA0 D;  3AUH A;  3CI7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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