1I50E

Rna polymerase ii crystal form ii at 2.8 a resolution
Total Genus 64
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
215
structure length
215
Chain Sequence
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 64
structure length 215
sequence length 215
ec nomenclature
pdb deposition date 2001-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 1i50E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 1i50E02
5C44E 3PO2E 3GTJE 1Y1VE 4A3DE 3HKZH 5IYDE 1Y1WE 5C4JE 2PMZH 4A3GE 4C3HE 5M5YE 3FKIE 3S17E 1I6HE 5M5XE 3I4ME 5C4XE 1SFOE 1TWCE 5FJ8E 3HOYE 4BXXE 2E2IE 3M3YE 3HOUE 2VUME 4A3FE 3S16E 4A3IE 3GTKE 2JA7E 2R92E 2WAQH 3H0GE 4X6AE 2WB1H 4Y7NE 3S1ME 3HOZE 4BY1E 3S2DE 1TWAE 5FLME 4A3JE 4A3ME 4BY7E 5IP7E 1TWHE 2NVQE 2NVTE 1I3QE 3RZDE 5M5WE 3S1QE 3HOWE 3RZOE 3S1RE 3HOVE 1DZFA 3PO3E 1R9TE 2B63E 1K83E 3GTQE 4QIWH 1TWFE 2E2JE 2E2HE 1EIKA 4C2ME 2JA8E 4C3IE 3GTGE 5IYCE 2R93E 3S2HE 5IYBE 4A3LE 2JA6E 3M4OE 3I4NE 4Y52E 4A3EE 3GTME 2NVYE 3CQZE 5IP9E 4C3JE 3GTLE 4BBRE 1TWGE 3H3VF 3GTOE 4AYBH 2NVXE 4A3BE 3S1NE 2JA5E 5M3FE 2R7ZE 2Y0SH 2YU9E 3S15E 1WCME 4BBSE 5C3EE 3GTPE 4A3KE 1I50E 4A3CE 3K7AE 3HOXE 4A93E 3S14E 5M3ME
chains in the Genus database with same CATH superfamily
4A3KF 4G7HE 5C44E 1I50F 3PO2E 3GTJE 3K7AF 4KMUE 1Y1VE 4A3DE 4YFKE 3HOXF 3S14F 4OIOE 3HKZH 5IYDE 5M3MF 4A93F 5E18E 5C44F 3H3VG 1I6VE 3PO2F 3GTJF 1Y1WE 4A3DF 5IYDF 3CQZF 2PPBE 5C4JE 5TMFE 2A68E 4A3GE 2PMZH 4C3HE 1Y1WF 5BYHE 2WAQK 5M5YE 5C4JF 3FKIE 3S17E 1I6HE 4C3HF 4A3BF 3EQLE 5D4EE 2JA5F 5M5XE 4G7OE 3I4ME 1QKLA 5M3FF 5C4XE 5M5YF 4MEXE 1SFOE 1TWCE 5FJ8E 5M5XF 3I4MF 3HOYE 4BXXE 2E2IE 4BBSF 5C4XF 4LJZE 4JK1E 5C3EF 1SFOF 4YG2E 3GTPF 1TWCF 3M3YE 4A3CF 3HOUE 5FJ8F 4XSZE 2VUME 4A3FE 2E2IF 3HOYF 1SMYE 3S16E 4A3IE 3GTKE 2JA7E 2R92E 2WAQH 3M3YF 3H0GE 1Y1VF 4X6AE 2BE5E 2WB1H 4Y7NE 4XLNE 4A3FF 2VUMF 3S1ME 2O5JE 3S16F 3HOZE 4BY1E 2JA7F 2R92F 3S2DE 3H0GF 4YFNE 1TWAE 4X6AF 2WB1I 2KRXA 5FLME 4A3JE 4A3ME 4BY7E 2A69E 4QIWK 5TMCE 4BY1F 4MQ9E 3HOZF 3S2DF 1YNNK 4A3GF 5IP7E 1TWAF 4OIRE 1TWHE 2NVQE 1YNJK 4MEYE 2NVTE 1I3QE 5FLMF 4BY7F 1IW7E 3FKIF 4A3JF 4A3MF 3S17F 1I6HF 3RZDE 5E17E 4LK0E 5IP7F 5M5WE 1HQME 2NVQF 3S1QE 2NVTF 1I3QF 3HOWE 3RZOE 3S1RE 3RZDF 3HOVE 5M5WF 1DZFA 3PO3E 4BXXF 4Q4ZE 3S1QF 1R9TE 2B63E 1K83E 4GZYE 3HOWF 4OINE 3GTQE 3S1RF 4QIWH 3HOUF 3HOVF 1TWFE 2E2JE 3PO3F 4OIPE 1R9TF 2B63F 2E2HE 1K83F 1EIKA 4A3IF 4ZH4E 3GTKF 4C2ME 3GTQF 2JA8E 5D4DE 4C3IE 3GTGE 4AYBK 5IYCE 2E2JF 4Y7NF 2R93E 3S1MF 2E2HF 3S2HE 4YFXE 2A6HE 2JA8F 1ZYRE 5IYBE 4C3IF 4A3LE 5IYCF 2R93F 2JA6E 3M4OE 3I4NE 4KN4E 4Y52E 3S2HF 5D4CE 5IYBF 4A3EE 2CW0E 3GTME 1TWHF 2NVYE 4A3LF 3CQZE 5IP9E 4C3JE 4G7ZE 2JA6F 3I4NF 3M4OF 3GTLE 4Y52F 4XSXE 4Q5SE 4BBRE 1TWGE 3H3VF 3GTOE 4A3EF 4OIQE 2O5IE 4XLPE 2NVYF 3GTMF 5IP9F 4C3JF 4AYBH 2NVXE 3GTLF 4A3BE 3S1NE 3RZOF 3HKZK 4LLGE 1TWGF 4BBRF 2JA5E 3GTOF 5M3FE 2R7ZE 2NVXF 2Y0SH 3DXJE 4LK1E 3WODE 3S1NF 2YU9E 3S15E 1TWFF 1WCME 2PMZK 4BBSE 2A6EE 2R7ZF 5IPLE 5C3EE 3GTPE 2Y0SI 4A3KE 4C2MF 1I50E 4A3CE 3K7AE 3HOXE 2YU9F 3S15F 4A93E 3S14E 1WCMF 3GTGF 4KN7E 5M3ME
chains in the Genus database with same CATH topology
5C44E 3PO2E 3GTJE 1Y1VE 4A3DE 3HKZH 5IYDE 1Y1WE 5C4JE 2PMZH 4A3GE 4C3HE 5M5YE 3FKIE 3S17E 1I6HE 5M5XE 3I4ME 5C4XE 1SFOE 1TWCE 5FJ8E 3HOYE 4BXXE 2E2IE 3M3YE 3HOUE 2VUME 4A3FE 3S16E 4A3IE 3GTKE 2JA7E 2R92E 2WAQH 3H0GE 4X6AE 2WB1H 4Y7NE 3S1ME 3HOZE 4BY1E 3S2DE 1TWAE 5FLME 4A3JE 4A3ME 4BY7E 5IP7E 1TWHE 2NVQE 2NVTE 1I3QE 3RZDE 5M5WE 3S1QE 3HOWE 3RZOE 3S1RE 3HOVE 1DZFA 3PO3E 1R9TE 2B63E 1K83E 3GTQE 4QIWH 1TWFE 2E2JE 2E2HE 1EIKA 4C2ME 2JA8E 4C3IE 3GTGE 5IYCE 2R93E 3S2HE 5IYBE 4A3LE 2JA6E 3M4OE 3I4NE 4Y52E 4A3EE 3GTME 2NVYE 3CQZE 5IP9E 4C3JE 3GTLE 4BBRE 1TWGE 3H3VF 3GTOE 4AYBH 2NVXE 4A3BE 3S1NE 2JA5E 5M3FE 2R7ZE 2Y0SH 2YU9E 3S15E 1WCME 4BBSE 5C3EE 3GTPE 4A3KE 1I50E 4A3CE 3K7AE 3HOXE 4A93E 3S14E 5M3ME
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C44 E;  3PO2 E;  3GTJ E;  1Y1V E;  4A3D E;  3HKZ H;  5IYD E;  1Y1W E;  5C4J E;  2PMZ H;  4A3G E;  4C3H E;  5M5Y E;  3FKI E;  3S17 E;  1I6H E;  5M5X E;  3I4M E;  5C4X E;  1SFO E;  1TWC E;  5FJ8 E;  3HOY E;  4BXX E;  2E2I E;  3M3Y E;  3HOU E;  2VUM E;  4A3F E;  3S16 E;  4A3I E;  3GTK E;  2JA7 E;  2R92 E;  2WAQ H;  3H0G E;  4X6A E;  2WB1 H;  4Y7N E;  3S1M E;  3HOZ E;  4BY1 E;  3S2D E;  1TWA E;  5FLM E;  4A3J E;  4A3M E;  4BY7 E;  5IP7 E;  1TWH E;  2NVQ E;  2NVT E;  1I3Q E;  3RZD E;  5M5W E;  3S1Q E;  3HOW E;  3RZO E;  3S1R E;  3HOV E;  1DZF A;  3PO3 E;  1R9T E;  2B63 E;  1K83 E;  3GTQ E;  4QIW H;  1TWF E;  2E2J E;  2E2H E;  1EIK A;  4C2M E;  2JA8 E;  4C3I E;  3GTG E;  5IYC E;  2R93 E;  3S2H E;  5IYB E;  4A3L E;  2JA6 E;  3M4O E;  3I4N E;  4Y52 E;  4A3E E;  3GTM E;  2NVY E;  3CQZ E;  5IP9 E;  4C3J E;  3GTL E;  4BBR E;  1TWG E;  3H3V F;  3GTO E;  4AYB H;  2NVX E;  4A3B E;  3S1N E;  2JA5 E;  5M3F E;  2R7Z E;  2Y0S H;  2YU9 E;  3S15 E;  1WCM E;  4BBS E;  5C3E E;  3GTP E;  4A3K E;  1I50 E;  4A3C E;  3K7A E;  3HOX E;  4A93 E;  3S14 E;  5M3M E; 
#chains in the Genus database with same CATH topology
 4A3K F;  4G7H E;  5C44 E;  1I50 F;  3PO2 E;  3GTJ E;  3K7A F;  4KMU E;  1Y1V E;  4A3D E;  4YFK E;  3HOX F;  3S14 F;  4OIO E;  3HKZ H;  5IYD E;  5M3M F;  4A93 F;  5E18 E;  5C44 F;  3H3V G;  1I6V E;  3PO2 F;  3GTJ F;  1Y1W E;  4A3D F;  5IYD F;  3CQZ F;  2PPB E;  5C4J E;  5TMF E;  2A68 E;  4A3G E;  2PMZ H;  4C3H E;  1Y1W F;  5BYH E;  2WAQ K;  5M5Y E;  5C4J F;  3FKI E;  3S17 E;  1I6H E;  4C3H F;  4A3B F;  3EQL E;  5D4E E;  2JA5 F;  5M5X E;  4G7O E;  3I4M E;  1QKL A;  5M3F F;  5C4X E;  5M5Y F;  4MEX E;  1SFO E;  1TWC E;  5FJ8 E;  5M5X F;  3I4M F;  3HOY E;  4BXX E;  2E2I E;  4BBS F;  5C4X F;  4LJZ E;  4JK1 E;  5C3E F;  1SFO F;  4YG2 E;  3GTP F;  1TWC F;  3M3Y E;  4A3C F;  3HOU E;  5FJ8 F;  4XSZ E;  2VUM E;  4A3F E;  2E2I F;  3HOY F;  1SMY E;  3S16 E;  4A3I E;  3GTK E;  2JA7 E;  2R92 E;  2WAQ H;  3M3Y F;  3H0G E;  1Y1V F;  4X6A E;  2BE5 E;  2WB1 H;  4Y7N E;  4XLN E;  4A3F F;  2VUM F;  3S1M E;  2O5J E;  3S16 F;  3HOZ E;  4BY1 E;  2JA7 F;  2R92 F;  3S2D E;  3H0G F;  4YFN E;  1TWA E;  4X6A F;  2WB1 I;  2KRX A;  5FLM E;  4A3J E;  4A3M E;  4BY7 E;  2A69 E;  4QIW K;  5TMC E;  4BY1 F;  4MQ9 E;  3HOZ F;  3S2D F;  1YNN K;  4A3G F;  5IP7 E;  1TWA F;  4OIR E;  1TWH E;  2NVQ E;  1YNJ K;  4MEY E;  2NVT E;  1I3Q E;  5FLM F;  4BY7 F;  1IW7 E;  3FKI F;  4A3J F;  4A3M F;  3S17 F;  1I6H F;  3RZD E;  5E17 E;  4LK0 E;  5IP7 F;  5M5W E;  1HQM E;  2NVQ F;  3S1Q E;  2NVT F;  1I3Q F;  3HOW E;  3RZO E;  3S1R E;  3RZD F;  3HOV E;  5M5W F;  1DZF A;  3PO3 E;  4BXX F;  4Q4Z E;  3S1Q F;  1R9T E;  2B63 E;  1K83 E;  4GZY E;  3HOW F;  4OIN E;  3GTQ E;  3S1R F;  4QIW H;  3HOU F;  3HOV F;  1TWF E;  2E2J E;  3PO3 F;  4OIP E;  1R9T F;  2B63 F;  2E2H E;  1K83 F;  1EIK A;  4A3I F;  4ZH4 E;  3GTK F;  4C2M E;  3GTQ F;  2JA8 E;  5D4D E;  4C3I E;  3GTG E;  4AYB K;  5IYC E;  2E2J F;  4Y7N F;  2R93 E;  3S1M F;  2E2H F;  3S2H E;  4YFX E;  2A6H E;  2JA8 F;  1ZYR E;  5IYB E;  4C3I F;  4A3L E;  5IYC F;  2R93 F;  2JA6 E;  3M4O E;  3I4N E;  4KN4 E;  4Y52 E;  3S2H F;  5D4C E;  5IYB F;  4A3E E;  2CW0 E;  3GTM E;  1TWH F;  2NVY E;  4A3L F;  3CQZ E;  5IP9 E;  4C3J E;  4G7Z E;  2JA6 F;  3I4N F;  3M4O F;  3GTL E;  4Y52 F;  4XSX E;  4Q5S E;  4BBR E;  1TWG E;  3H3V F;  3GTO E;  4A3E F;  4OIQ E;  2O5I E;  4XLP E;  2NVY F;  3GTM F;  5IP9 F;  4C3J F;  4AYB H;  2NVX E;  3GTL F;  4A3B E;  3S1N E;  3RZO F;  3HKZ K;  4LLG E;  1TWG F;  4BBR F;  2JA5 E;  3GTO F;  5M3F E;  2R7Z E;  2NVX F;  2Y0S H;  3DXJ E;  4LK1 E;  3WOD E;  3S1N F;  2YU9 E;  3S15 E;  1TWF F;  1WCM E;  2PMZ K;  4BBS E;  2A6E E;  2R7Z F;  5IPL E;  5C3E E;  3GTP E;  2Y0S I;  4A3K E;  4C2M F;  1I50 E;  4A3C E;  3K7A E;  3HOX E;  2YU9 F;  3S15 F;  4A93 E;  3S14 E;  1WCM F;  3GTG F;  4KN7 E;  5M3M E; 
#chains in the Genus database with same CATH homology
 5C44 E;  3PO2 E;  3GTJ E;  1Y1V E;  4A3D E;  3HKZ H;  5IYD E;  1Y1W E;  5C4J E;  2PMZ H;  4A3G E;  4C3H E;  5M5Y E;  3FKI E;  3S17 E;  1I6H E;  5M5X E;  3I4M E;  5C4X E;  1SFO E;  1TWC E;  5FJ8 E;  3HOY E;  4BXX E;  2E2I E;  3M3Y E;  3HOU E;  2VUM E;  4A3F E;  3S16 E;  4A3I E;  3GTK E;  2JA7 E;  2R92 E;  2WAQ H;  3H0G E;  4X6A E;  2WB1 H;  4Y7N E;  3S1M E;  3HOZ E;  4BY1 E;  3S2D E;  1TWA E;  5FLM E;  4A3J E;  4A3M E;  4BY7 E;  5IP7 E;  1TWH E;  2NVQ E;  2NVT E;  1I3Q E;  3RZD E;  5M5W E;  3S1Q E;  3HOW E;  3RZO E;  3S1R E;  3HOV E;  1DZF A;  3PO3 E;  1R9T E;  2B63 E;  1K83 E;  3GTQ E;  4QIW H;  1TWF E;  2E2J E;  2E2H E;  1EIK A;  4C2M E;  2JA8 E;  4C3I E;  3GTG E;  5IYC E;  2R93 E;  3S2H E;  5IYB E;  4A3L E;  2JA6 E;  3M4O E;  3I4N E;  4Y52 E;  4A3E E;  3GTM E;  2NVY E;  3CQZ E;  5IP9 E;  4C3J E;  3GTL E;  4BBR E;  1TWG E;  3H3V F;  3GTO E;  4AYB H;  2NVX E;  4A3B E;  3S1N E;  2JA5 E;  5M3F E;  2R7Z E;  2Y0S H;  2YU9 E;  3S15 E;  1WCM E;  4BBS E;  5C3E E;  3GTP E;  4A3K E;  1I50 E;  4A3C E;  3K7A E;  3HOX E;  4A93 E;  3S14 E;  5M3M E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...