1I50F

Rna polymerase ii crystal form ii at 2.8 a resolution
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 25
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2001-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1i50F00
4MEYE 4C3HF 4A3JF 2VUMF 3HOUF 3S1RF 4A3BF 2CW0E 4A3CF 4Q4ZE 1Y1WF 1TWAF 4LLGE 3GTQF 2O5JE 5IP7F 1YNJK 3EQLE 4A3MF 5IP9F 4ZH4E 2BE5E 1IW7E 4G7ZE 4YFKE 4YFNE 5M5XF 5M5YF 3DXJE 4Y7NF 2R93F 3HOVF 3WODE 3S16F 1WCMF 4BY7F 4AYBK 2NVTF 2E2JF 3S15F 3HKZK 4KN7E 2Y0SI 2E2HF 3S1NF 2A69E 3GTMF 4G7OE 1TWHF 4OIRE 5FLMF 1I3QF 5C4XF 2PPBE 4G7HE 3K7AF 1SFOF 3S17F 3M3YF 1ZYRE 5D4CE 4A93F 4A3EF 4C3IF 4XLPE 5TMCE 1Y1VF 5TMFE 3HOXF 2WAQK 5M3MF 3GTJF 4C3JF 4Y52F 2JA5F 3H3VG 3GTOF 4C2MF 5BYHE 4KN4E 5C3EF 3FKIF 4A3IF 3S14F 5E18E 4KMUE 5E17E 1K83F 2NVYF 2A6EE 5IYBF 3M4OF 1R9TF 4XSXE 4BBRF 3S2DF 4LJZE 4GZYE 4BXXF 3PO2F 4OIPE 4A3KF 4MEXE 5D4DE 1YNNK 2WB1I 4OIQE 2JA8F 3HOWF 4A3FF 4A3DF 2A6HE 2B63F 4A3GF 1I6VE 2E2IF 3S2HF 4YG2E 1QKLA 4YFXE 4X6AF 2PMZK 5IPLE 3CQZF 1TWGF 4MQ9E 5IYDF 2O5IE 5C4JF 4Q5SE 1TWCF 4LK0E 4LK1E 3RZDF 4BBSF 1I6HF 3S1QF 4A3LF 4JK1E 5D4EE 1HQME 4XSZE 2NVXF 4OIOE 3S1MF 5M5WF 5C44F 2JA6F 3I4NF 3HOYF 4XLNE 3PO3F 5M3FF 2JA7F 5IYCF 3GTKF 3GTGF 3GTPF 1I50F 3GTLF 3RZOF 1SMYE 1TWFF 4OINE 3I4MF 2YU9F 4BY1F 3HOZF 2NVQF 5FJ8F 2R7ZF 2A68E 2R92F 3H0GF
chains in the Genus database with same CATH superfamily
4MEYE 4C3HF 4A3JF 5M3FE 5M5XE 5M5YE 2VUMF 3GTKE 3S1RF 3HOUF 2R93E 4A3BF 2CW0E 4A3CF 4Q4ZE 1Y1WF 1TWAF 4LLGE 3S16E 1WCME 3I4ME 4BY7E 2YU9E 2NVTE 2E2JE 3S15E 4BY1E 3GTQF 2E2HE 2O5JE 2WB1H 3S1NE 5IP7F 1YNJK 3EQLE 5FJ8E 4A3MF 5IP9F 4ZH4E 2NVQE 2R7ZE 2BE5E 1TWHE 4QIWK 1IW7E 1I3QE 4YFKE 4G7ZE 4YFNE 3I4NE 5M5XF 5M5YF 3DXJE 4Y7NF 1EIKA 2R93F 3K7AE 2VUME 3HOVF 3WODE 3M3YE 3S16F 1WCMF 4A3BE 4BY7F 4AYBK 2NVTF 1Y1WE 2E2JF 3S15F 3HKZK 4KN7E 2Y0SI 2E2HF 4C3IE 3S1NF 2A69E 3GTMF 4G7OE 3GTQE 3HOXE 1TWHF 4A3ME 4OIRE 5M3ME 5FLMF 5IP9E 1I3QF 5C4XF 2PPBE 3GTJE 4G7HE 3K7AF 4C3JE 1SFOF 3S17F 3GTOE 4Y7NE 3M3YF 1ZYRE 5D4CE 2KRXA 3HOVE 2PMZH 4A93F 5C3EE 4A3IE 4A3EF 3S14E 4C3IF 4XLPE 5TMCE 1Y1VF 5TMFE 2NVYE 3HOXF 2WAQK 3GTME 5M3MF 5IYBE 3M4OE 5FLME 3GTJF 5C4XE 4C3JF 4Y52F 1R9TE 2JA5F 3GTOF 3H3VG 4C2MF 3S2DE 5BYHE 1SFOE 4KN4E 3S17E 5C3EF 3FKIF 4A3IF 3S14F 5E18E 3PO2E 4KMUE 4BXXE 5E17E 4A3KE 4A93E 1K83F 4A3EE 2NVYF 2JA8E 2A6EE 4QIWH 3HOWE 4A3FE 1Y1VE 4A3DE 5IYBF 3M4OF 4A3GE 1R9TF 4XSXE 4BBRF 2E2IE 3S2DF 4AYBH 3S2HE 4LJZE 2JA5E 4Y52E 4GZYE 3HKZH 4C2ME 4BXXF 4X6AE 3PO2F 4OIPE 4A3KF 4MEXE 1DZFA 3FKIE 3CQZE 5D4DE 1TWGE 1YNNK 2WB1I 4OIQE 2JA8F 3HOWF 4A3FF 4A3DF 1K83E 2A6HE 1TWCE 2B63F 4A3GF 1I6VE 3RZDE 2E2IF 3S2HF 4BBSE 1I6HE 4YG2E 3S1QE 1QKLA 4YFXE 4BBRE 2NVXE 3H3VF 3S1ME 5M5WE 2PMZK 4X6AF 5IPLE 5C44E 3CQZF 1TWGF 2WAQH 4MQ9E 5IYDF 2O5IE 3HOYE 5C4JF 4Q5SE 3PO3E 1TWCF 2JA7E 5IYCE 4LK0E 4LK1E 3GTGE 1I50E 2B63E 3GTLE 3RZDF 3GTPE 1I6HF 3RZOE 4BBSF 3S1QF 4A3LF 4JK1E 1TWFE 1HQME 4XSZE 5D4EE 2NVXF 4OIOE 3S1MF 5M5WF 5C44F 2JA6F 3HOZE 3I4NF 2R92E 3HOYF 3H0GE 5IYDE 4XLNE 3PO3F 5M3FF 4C3HE 2JA7F 5IYCF 5C4JE 4A3JE 3GTKF 3GTGF 3GTPF 1I50F 3GTLF 3HOUE 3S1RE 3RZOF 1SMYE 4A3CE 1TWFF 4OINE 3I4MF 2YU9F 1TWAE 4BY1F 4A3LE 3HOZF 2NVQF 5FJ8F 2R7ZF 2A68E 2Y0SH 2R92F 2JA6E 5IP7E 3H0GF
chains in the Genus database with same CATH topology
4MEYE 4C3HF 4A3JF 2VUMF 3HOUF 3S1RF 4A3BF 2CW0E 4A3CF 4Q4ZE 1Y1WF 1TWAF 4LLGE 3GTQF 2O5JE 5IP7F 1YNJK 3EQLE 4A3MF 5IP9F 4ZH4E 2BE5E 4QIWK 1IW7E 4G7ZE 4YFKE 4YFNE 5M5XF 5M5YF 3DXJE 4Y7NF 2R93F 3HOVF 3WODE 3S16F 1WCMF 4BY7F 4AYBK 2NVTF 2E2JF 3S15F 3HKZK 4KN7E 2Y0SI 2E2HF 3S1NF 2A69E 3GTMF 4G7OE 1TWHF 4OIRE 5FLMF 1I3QF 5C4XF 2PPBE 4G7HE 3K7AF 1SFOF 3S17F 3M3YF 1ZYRE 5D4CE 2KRXA 4A93F 4A3EF 4C3IF 4XLPE 5TMCE 1Y1VF 5TMFE 3HOXF 2WAQK 5M3MF 3GTJF 4C3JF 4Y52F 2JA5F 3H3VG 3GTOF 4C2MF 5BYHE 4KN4E 5C3EF 3FKIF 4A3IF 3S14F 5E18E 4KMUE 5E17E 1K83F 2NVYF 2A6EE 5IYBF 3M4OF 1R9TF 4XSXE 4BBRF 3S2DF 4LJZE 4GZYE 4BXXF 3PO2F 4OIPE 4A3KF 4MEXE 5D4DE 1YNNK 2WB1I 4OIQE 2JA8F 3HOWF 4A3FF 4A3DF 2A6HE 2B63F 4A3GF 1I6VE 2E2IF 3S2HF 4YG2E 1QKLA 4YFXE 4X6AF 2PMZK 5IPLE 3CQZF 1TWGF 4MQ9E 5IYDF 2O5IE 5C4JF 4Q5SE 1TWCF 4LK0E 4LK1E 3RZDF 4BBSF 1I6HF 3S1QF 4A3LF 4JK1E 5D4EE 1HQME 4XSZE 2NVXF 4OIOE 3S1MF 5M5WF 5C44F 2JA6F 3I4NF 3HOYF 4XLNE 3PO3F 5M3FF 2JA7F 5IYCF 3GTKF 3GTGF 3GTPF 1I50F 3GTLF 3RZOF 1SMYE 1TWFF 4OINE 3I4MF 2YU9F 4BY1F 3HOZF 2NVQF 5FJ8F 2R7ZF 2A68E 2R92F 3H0GF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MEY E;  4C3H F;  4A3J F;  2VUM F;  3HOU F;  3S1R F;  4A3B F;  2CW0 E;  4A3C F;  4Q4Z E;  1Y1W F;  1TWA F;  4LLG E;  3GTQ F;  2O5J E;  5IP7 F;  1YNJ K;  3EQL E;  4A3M F;  5IP9 F;  4ZH4 E;  2BE5 E;  1IW7 E;  4G7Z E;  4YFK E;  4YFN E;  5M5X F;  5M5Y F;  3DXJ E;  4Y7N F;  2R93 F;  3HOV F;  3WOD E;  3S16 F;  1WCM F;  4BY7 F;  4AYB K;  2NVT F;  2E2J F;  3S15 F;  3HKZ K;  4KN7 E;  2Y0S I;  2E2H F;  3S1N F;  2A69 E;  3GTM F;  4G7O E;  1TWH F;  4OIR E;  5FLM F;  1I3Q F;  5C4X F;  2PPB E;  4G7H E;  3K7A F;  1SFO F;  3S17 F;  3M3Y F;  1ZYR E;  5D4C E;  4A93 F;  4A3E F;  4C3I F;  4XLP E;  5TMC E;  1Y1V F;  5TMF E;  3HOX F;  2WAQ K;  5M3M F;  3GTJ F;  4C3J F;  4Y52 F;  2JA5 F;  3H3V G;  3GTO F;  4C2M F;  5BYH E;  4KN4 E;  5C3E F;  3FKI F;  4A3I F;  3S14 F;  5E18 E;  4KMU E;  5E17 E;  1K83 F;  2NVY F;  2A6E E;  5IYB F;  3M4O F;  1R9T F;  4XSX E;  4BBR F;  3S2D F;  4LJZ E;  4GZY E;  4BXX F;  3PO2 F;  4OIP E;  4A3K F;  4MEX E;  5D4D E;  1YNN K;  2WB1 I;  4OIQ E;  2JA8 F;  3HOW F;  4A3F F;  4A3D F;  2A6H E;  2B63 F;  4A3G F;  1I6V E;  2E2I F;  3S2H F;  4YG2 E;  1QKL A;  4YFX E;  4X6A F;  2PMZ K;  5IPL E;  3CQZ F;  1TWG F;  4MQ9 E;  5IYD F;  2O5I E;  5C4J F;  4Q5S E;  1TWC F;  4LK0 E;  4LK1 E;  3RZD F;  4BBS F;  1I6H F;  3S1Q F;  4A3L F;  4JK1 E;  5D4E E;  1HQM E;  4XSZ E;  2NVX F;  4OIO E;  3S1M F;  5M5W F;  5C44 F;  2JA6 F;  3I4N F;  3HOY F;  4XLN E;  3PO3 F;  5M3F F;  2JA7 F;  5IYC F;  3GTK F;  3GTG F;  3GTP F;  1I50 F;  3GTL F;  3RZO F;  1SMY E;  1TWF F;  4OIN E;  3I4M F;  2YU9 F;  4BY1 F;  3HOZ F;  2NVQ F;  5FJ8 F;  2R7Z F;  2A68 E;  2R92 F;  3H0G F; 
#chains in the Genus database with same CATH topology
 4MEY E;  4C3H F;  4A3J F;  5M3F E;  5M5X E;  5M5Y E;  2VUM F;  3GTK E;  3S1R F;  3HOU F;  2R93 E;  4A3B F;  2CW0 E;  4A3C F;  4Q4Z E;  1Y1W F;  1TWA F;  4LLG E;  3S16 E;  1WCM E;  3I4M E;  4BY7 E;  2YU9 E;  2NVT E;  2E2J E;  3S15 E;  4BY1 E;  3GTQ F;  2E2H E;  2O5J E;  2WB1 H;  3S1N E;  5IP7 F;  1YNJ K;  3EQL E;  5FJ8 E;  4A3M F;  5IP9 F;  4ZH4 E;  2NVQ E;  2R7Z E;  2BE5 E;  1TWH E;  4QIW K;  1IW7 E;  1I3Q E;  4YFK E;  4G7Z E;  4YFN E;  3I4N E;  5M5X F;  5M5Y F;  3DXJ E;  4Y7N F;  1EIK A;  2R93 F;  3K7A E;  2VUM E;  3HOV F;  3WOD E;  3M3Y E;  3S16 F;  1WCM F;  4A3B E;  4BY7 F;  4AYB K;  2NVT F;  1Y1W E;  2E2J F;  3S15 F;  3HKZ K;  4KN7 E;  2Y0S I;  2E2H F;  4C3I E;  3S1N F;  2A69 E;  3GTM F;  4G7O E;  3GTQ E;  3HOX E;  1TWH F;  4A3M E;  4OIR E;  5M3M E;  5FLM F;  5IP9 E;  1I3Q F;  5C4X F;  2PPB E;  3GTJ E;  4G7H E;  3K7A F;  4C3J E;  1SFO F;  3S17 F;  3GTO E;  4Y7N E;  3M3Y F;  1ZYR E;  5D4C E;  2KRX A;  3HOV E;  2PMZ H;  4A93 F;  5C3E E;  4A3I E;  4A3E F;  3S14 E;  4C3I F;  4XLP E;  5TMC E;  1Y1V F;  5TMF E;  2NVY E;  3HOX F;  2WAQ K;  3GTM E;  5M3M F;  5IYB E;  3M4O E;  5FLM E;  3GTJ F;  5C4X E;  4C3J F;  4Y52 F;  1R9T E;  2JA5 F;  3GTO F;  3H3V G;  4C2M F;  3S2D E;  5BYH E;  1SFO E;  4KN4 E;  3S17 E;  5C3E F;  3FKI F;  4A3I F;  3S14 F;  5E18 E;  3PO2 E;  4KMU E;  4BXX E;  5E17 E;  4A3K E;  4A93 E;  1K83 F;  4A3E E;  2NVY F;  2JA8 E;  2A6E E;  4QIW H;  3HOW E;  4A3F E;  1Y1V E;  4A3D E;  5IYB F;  3M4O F;  4A3G E;  1R9T F;  4XSX E;  4BBR F;  2E2I E;  3S2D F;  4AYB H;  3S2H E;  4LJZ E;  2JA5 E;  4Y52 E;  4GZY E;  3HKZ H;  4C2M E;  4BXX F;  4X6A E;  3PO2 F;  4OIP E;  4A3K F;  4MEX E;  1DZF A;  3FKI E;  3CQZ E;  5D4D E;  1TWG E;  1YNN K;  2WB1 I;  4OIQ E;  2JA8 F;  3HOW F;  4A3F F;  4A3D F;  1K83 E;  2A6H E;  1TWC E;  2B63 F;  4A3G F;  1I6V E;  3RZD E;  2E2I F;  3S2H F;  4BBS E;  1I6H E;  4YG2 E;  3S1Q E;  1QKL A;  4YFX E;  4BBR E;  2NVX E;  3H3V F;  3S1M E;  5M5W E;  2PMZ K;  4X6A F;  5IPL E;  5C44 E;  3CQZ F;  1TWG F;  2WAQ H;  4MQ9 E;  5IYD F;  2O5I E;  3HOY E;  5C4J F;  4Q5S E;  3PO3 E;  1TWC F;  2JA7 E;  5IYC E;  4LK0 E;  4LK1 E;  3GTG E;  1I50 E;  2B63 E;  3GTL E;  3RZD F;  3GTP E;  1I6H F;  3RZO E;  4BBS F;  3S1Q F;  4A3L F;  4JK1 E;  1TWF E;  1HQM E;  4XSZ E;  5D4E E;  2NVX F;  4OIO E;  3S1M F;  5M5W F;  5C44 F;  2JA6 F;  3HOZ E;  3I4N F;  2R92 E;  3HOY F;  3H0G E;  5IYD E;  4XLN E;  3PO3 F;  5M3F F;  4C3H E;  2JA7 F;  5IYC F;  5C4J E;  4A3J E;  3GTK F;  3GTG F;  3GTP F;  1I50 F;  3GTL F;  3HOU E;  3S1R E;  3RZO F;  1SMY E;  4A3C E;  1TWF F;  4OIN E;  3I4M F;  2YU9 F;  1TWA E;  4BY1 F;  4A3L E;  3HOZ F;  2NVQ F;  5FJ8 F;  2R7Z F;  2A68 E;  2Y0S H;  2R92 F;  2JA6 E;  5IP7 E;  3H0G F; 
#chains in the Genus database with same CATH homology
 4MEY E;  4C3H F;  4A3J F;  2VUM F;  3HOU F;  3S1R F;  4A3B F;  2CW0 E;  4A3C F;  4Q4Z E;  1Y1W F;  1TWA F;  4LLG E;  3GTQ F;  2O5J E;  5IP7 F;  1YNJ K;  3EQL E;  4A3M F;  5IP9 F;  4ZH4 E;  2BE5 E;  4QIW K;  1IW7 E;  4G7Z E;  4YFK E;  4YFN E;  5M5X F;  5M5Y F;  3DXJ E;  4Y7N F;  2R93 F;  3HOV F;  3WOD E;  3S16 F;  1WCM F;  4BY7 F;  4AYB K;  2NVT F;  2E2J F;  3S15 F;  3HKZ K;  4KN7 E;  2Y0S I;  2E2H F;  3S1N F;  2A69 E;  3GTM F;  4G7O E;  1TWH F;  4OIR E;  5FLM F;  1I3Q F;  5C4X F;  2PPB E;  4G7H E;  3K7A F;  1SFO F;  3S17 F;  3M3Y F;  1ZYR E;  5D4C E;  2KRX A;  4A93 F;  4A3E F;  4C3I F;  4XLP E;  5TMC E;  1Y1V F;  5TMF E;  3HOX F;  2WAQ K;  5M3M F;  3GTJ F;  4C3J F;  4Y52 F;  2JA5 F;  3H3V G;  3GTO F;  4C2M F;  5BYH E;  4KN4 E;  5C3E F;  3FKI F;  4A3I F;  3S14 F;  5E18 E;  4KMU E;  5E17 E;  1K83 F;  2NVY F;  2A6E E;  5IYB F;  3M4O F;  1R9T F;  4XSX E;  4BBR F;  3S2D F;  4LJZ E;  4GZY E;  4BXX F;  3PO2 F;  4OIP E;  4A3K F;  4MEX E;  5D4D E;  1YNN K;  2WB1 I;  4OIQ E;  2JA8 F;  3HOW F;  4A3F F;  4A3D F;  2A6H E;  2B63 F;  4A3G F;  1I6V E;  2E2I F;  3S2H F;  4YG2 E;  1QKL A;  4YFX E;  4X6A F;  2PMZ K;  5IPL E;  3CQZ F;  1TWG F;  4MQ9 E;  5IYD F;  2O5I E;  5C4J F;  4Q5S E;  1TWC F;  4LK0 E;  4LK1 E;  3RZD F;  4BBS F;  1I6H F;  3S1Q F;  4A3L F;  4JK1 E;  5D4E E;  1HQM E;  4XSZ E;  2NVX F;  4OIO E;  3S1M F;  5M5W F;  5C44 F;  2JA6 F;  3I4N F;  3HOY F;  4XLN E;  3PO3 F;  5M3F F;  2JA7 F;  5IYC F;  3GTK F;  3GTG F;  3GTP F;  1I50 F;  3GTL F;  3RZO F;  1SMY E;  1TWF F;  4OIN E;  3I4M F;  2YU9 F;  4BY1 F;  3HOZ F;  2NVQ F;  5FJ8 F;  2R7Z F;  2A68 E;  2R92 F;  3H0G F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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