1I6HE

Rna polymerase ii elongation complex
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
source organism Saccharomyces cerevisiae
molecule keywords 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3'
total genus 54
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2001-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 1i6hE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 1i6hE02
5M3ME 5C44E 3HOXE 3HKZH 3GTGE 3S14E 2B63E 3GTJE 4Y7NE 2VUME 1WCME 3S2HE 1Y1VE 4A3CE 3RZDE 5C3EE 2R92E 2WB1H 3HOYE 4BBRE 4X6AE 3S1QE 3PO3E 1TWCE 3GTPE 3HOUE 4A3EE 4A3BE 3FKIE 5M3FE 5IYCE 1Y1WE 2R93E 4BXXE 3S17E 4C2ME 2JA8E 1TWHE 4C3IE 3H3VF 3RZOE 3S1ME 4A3GE 4A3DE 2WAQH 2JA6E 1K83E 2JA5E 4AYBH 1TWFE 3GTKE 5M5YE 2NVXE 3K7AE 1I6HE 4C3JE 4A3KE 1TWAE 4BY7E 3GTLE 3I4NE 4BY1E 3I4ME 2PMZH 4BBSE 3GTME 3H0GE 4A93E 3GTOE 5FLME 3GTQE 2Y0SH 3M4OE 2NVYE 4A3LE 4QIWH 5M5XE 4C3HE 2NVTE 5C4JE 4A3JE 5IYBE 4Y52E 2R7ZE 2E2JE 4A3FE 1SFOE 1I50E 5C4XE 5IYDE 5M5WE 5IP7E 3S16E 3HOWE 3PO2E 3M3YE 3CQZE 1EIKA 3S15E 3S2DE 1TWGE 3S1NE 3S1RE 1R9TE 5IP9E 2NVQE 3HOZE 5FJ8E 4A3IE 2JA7E 3HOVE 2YU9E 1I3QE 2E2IE 2E2HE 4A3ME 1DZFA
chains in the Genus database with same CATH superfamily
5M3ME 4G7ZE 2JA7F 3HOVF 5C44E 4MQ9E 3HOXE 3HKZH 3GTGE 3S14E 1I3QF 2B63E 3GTJE 4Y7NE 2VUME 1I6VE 3EQLE 1Y1WF 1WCME 3S2HE 1Y1VE 4A3CE 3RZDE 5C3EE 2E2IF 2E2HF 2R92E 2PMZK 4KN4E 2WB1H 5M3MF 5E18E 4MEXE 3HOYE 4BBRE 4X6AE 3S1QE 3PO3E 1TWCE 5C44F 3HOXF 3GTPE 3HOUE 3GTGF 4A3EE 3S14F 2B63F 4A3BE 4Y7NF 3GTJF 2VUMF 2Y0SI 4OIQE 3FKIE 1Y1VF 3S2HF 4A3CF 3RZDF 5C3EF 5M3FE 5D4EE 2O5IE 5IYCE 1Y1WE 3K7AF 2R93E 2R92F 4BXXE 3S17E 4QIWK 4C2ME 5TMFE 2JA8E 4OIRE 3HOYF 4BBRF 4C3JF 3S1QF 4XSZE 3PO3F 2A69E 4X6AF 4OINE 1HQME 3GTPF 3HOUF 1TWHE 4C3IE 4A3EF 3H3VF 4A3BF 3RZOE 2O5JE 3S1ME 3FKIF 4A3GE 4LLGE 4A3DE 5M3FF 2WAQH 5IYCF 2JA6E 4LK0E 5IPLE 5D4CE 1K83E 2JA5E 4KMUE 5D4DE 3S17F 4C2MF 4BXXF 2R93F 2CW0E 4AYBH 1TWFE 2JA8F 3GTKE 4G7OE 5M5YE 2NVXE 3K7AE 1I6HE 4Q4ZE 1TWHF 4C3IF 4YFXE 3RZOF 4C3JE 3S1MF 4A3GF 4A3LF 4A3DF 4A3KE 1TWAE 4BY7E 4XSXE 5TMCE 5M5XF 4G7HE 2JA6F 4C3HF 1K83F 4JK1E 2JA5F 3GTLE 3I4NE 4BY1E 3I4ME 2PMZH 4BBSE 1TWFF 3GTME 3GTKF 5M5YF 2NVXF 3H0GE 4A93E 2R7ZF 1I6HF 3GTOE 1YNNK 5FLME 2WB1I 3GTQE 2Y0SH 1TWAF 4BY7F 4A3KF 3M4OE 2NVYE 4MEYE 3GTLF 4A3LE 4BY1F 4LK1E 3I4MF 3I4NF 5IP7F 4QIWH 4BBSF 5M5XE 3GTMF 2A6EE 4C3HE 2NVTE 5C4JE 3H0GF 4A3JE 4Q5SE 3GTOF 4A93F 5IYBE 4Y52E 5FLMF 2R7ZE 3GTQF 2E2JE 4A3FE 3DXJE 1SFOE 1IW7E 3M4OF 2BE5E 2NVYF 5BYHE 1I50E 4OIOE 5C4XE 2A68E 3HKZK 5IYDE 5C4JF 2NVTF 4KN7E 5M5WE 2A6HE 4A3JF 5IYBF 4Y52F 5IP7E 3HOZF 3WODE 3S16E 4AYBK 2E2JF 4A3FF 3HOWE 1QKLA 4A3IF 3PO2E 3M3YE 1SFOF 1ZYRE 4YFKE 2YU9F 1I50F 3CQZE 5C4XF 4LJZE 5E17E 1EIKA 3S15E 3S2DE 5IYDF 5M5WF 1TWGE 3S1NE 2PPBE 3S1RE 1R9TE 4A3MF 4XLNE 3S16F 5IP9E 4ZH4E 3HOWF 3PO2F 2NVQE 3M3YF 3HOZE 5FJ8E 4GZYE 3H3VG 3CQZF 4A3IE 2JA7E 2KRXA 4XLPE 1WCMF 3HOVE 3S2DF 3S15F 1SMYE 2YU9E 1I3QE 1TWGF 4YFNE 3S1NF 3S1RF 4YG2E 1R9TF 2WAQK 5IP9F 2E2IE 4OIPE 2E2HE 2NVQF 5FJ8F 1TWCF 4A3ME 1YNJK 1DZFA
chains in the Genus database with same CATH topology
5M3ME 5C44E 3HOXE 3HKZH 3GTGE 3S14E 2B63E 3GTJE 4Y7NE 2VUME 1WCME 3S2HE 1Y1VE 4A3CE 3RZDE 5C3EE 2R92E 2WB1H 3HOYE 4BBRE 4X6AE 3S1QE 3PO3E 1TWCE 3GTPE 3HOUE 4A3EE 4A3BE 3FKIE 5M3FE 5IYCE 1Y1WE 2R93E 4BXXE 3S17E 4C2ME 2JA8E 1TWHE 4C3IE 3H3VF 3RZOE 3S1ME 4A3GE 4A3DE 2WAQH 2JA6E 1K83E 2JA5E 4AYBH 1TWFE 3GTKE 5M5YE 2NVXE 3K7AE 1I6HE 4C3JE 4A3KE 1TWAE 4BY7E 3GTLE 3I4NE 4BY1E 3I4ME 2PMZH 4BBSE 3GTME 3H0GE 4A93E 3GTOE 5FLME 3GTQE 2Y0SH 3M4OE 2NVYE 4A3LE 4QIWH 5M5XE 4C3HE 2NVTE 5C4JE 4A3JE 5IYBE 4Y52E 2R7ZE 2E2JE 4A3FE 1SFOE 1I50E 5C4XE 5IYDE 5M5WE 5IP7E 3S16E 3HOWE 3PO2E 3M3YE 3CQZE 1EIKA 3S15E 3S2DE 1TWGE 3S1NE 3S1RE 1R9TE 5IP9E 2NVQE 3HOZE 5FJ8E 4A3IE 2JA7E 3HOVE 2YU9E 1I3QE 2E2IE 2E2HE 4A3ME 1DZFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5M3M E;  5C44 E;  3HOX E;  3HKZ H;  3GTG E;  3S14 E;  2B63 E;  3GTJ E;  4Y7N E;  2VUM E;  1WCM E;  3S2H E;  1Y1V E;  4A3C E;  3RZD E;  5C3E E;  2R92 E;  2WB1 H;  3HOY E;  4BBR E;  4X6A E;  3S1Q E;  3PO3 E;  1TWC E;  3GTP E;  3HOU E;  4A3E E;  4A3B E;  3FKI E;  5M3F E;  5IYC E;  1Y1W E;  2R93 E;  4BXX E;  3S17 E;  4C2M E;  2JA8 E;  1TWH E;  4C3I E;  3H3V F;  3RZO E;  3S1M E;  4A3G E;  4A3D E;  2WAQ H;  2JA6 E;  1K83 E;  2JA5 E;  4AYB H;  1TWF E;  3GTK E;  5M5Y E;  2NVX E;  3K7A E;  1I6H E;  4C3J E;  4A3K E;  1TWA E;  4BY7 E;  3GTL E;  3I4N E;  4BY1 E;  3I4M E;  2PMZ H;  4BBS E;  3GTM E;  3H0G E;  4A93 E;  3GTO E;  5FLM E;  3GTQ E;  2Y0S H;  3M4O E;  2NVY E;  4A3L E;  4QIW H;  5M5X E;  4C3H E;  2NVT E;  5C4J E;  4A3J E;  5IYB E;  4Y52 E;  2R7Z E;  2E2J E;  4A3F E;  1SFO E;  1I50 E;  5C4X E;  5IYD E;  5M5W E;  5IP7 E;  3S16 E;  3HOW E;  3PO2 E;  3M3Y E;  3CQZ E;  1EIK A;  3S15 E;  3S2D E;  1TWG E;  3S1N E;  3S1R E;  1R9T E;  5IP9 E;  2NVQ E;  3HOZ E;  5FJ8 E;  4A3I E;  2JA7 E;  3HOV E;  2YU9 E;  1I3Q E;  2E2I E;  2E2H E;  4A3M E;  1DZF A; 
#chains in the Genus database with same CATH topology
 5M3M E;  4G7Z E;  2JA7 F;  3HOV F;  5C44 E;  4MQ9 E;  3HOX E;  3HKZ H;  3GTG E;  3S14 E;  1I3Q F;  2B63 E;  3GTJ E;  4Y7N E;  2VUM E;  1I6V E;  3EQL E;  1Y1W F;  1WCM E;  3S2H E;  1Y1V E;  4A3C E;  3RZD E;  5C3E E;  2E2I F;  2E2H F;  2R92 E;  2PMZ K;  4KN4 E;  2WB1 H;  5M3M F;  5E18 E;  4MEX E;  3HOY E;  4BBR E;  4X6A E;  3S1Q E;  3PO3 E;  1TWC E;  5C44 F;  3HOX F;  3GTP E;  3HOU E;  3GTG F;  4A3E E;  3S14 F;  2B63 F;  4A3B E;  4Y7N F;  3GTJ F;  2VUM F;  2Y0S I;  4OIQ E;  3FKI E;  1Y1V F;  3S2H F;  4A3C F;  3RZD F;  5C3E F;  5M3F E;  5D4E E;  2O5I E;  5IYC E;  1Y1W E;  3K7A F;  2R93 E;  2R92 F;  4BXX E;  3S17 E;  4QIW K;  4C2M E;  5TMF E;  2JA8 E;  4OIR E;  3HOY F;  4BBR F;  4C3J F;  3S1Q F;  4XSZ E;  3PO3 F;  2A69 E;  4X6A F;  4OIN E;  1HQM E;  3GTP F;  3HOU F;  1TWH E;  4C3I E;  4A3E F;  3H3V F;  4A3B F;  3RZO E;  2O5J E;  3S1M E;  3FKI F;  4A3G E;  4LLG E;  4A3D E;  5M3F F;  2WAQ H;  5IYC F;  2JA6 E;  4LK0 E;  5IPL E;  5D4C E;  1K83 E;  2JA5 E;  4KMU E;  5D4D E;  3S17 F;  4C2M F;  4BXX F;  2R93 F;  2CW0 E;  4AYB H;  1TWF E;  2JA8 F;  3GTK E;  4G7O E;  5M5Y E;  2NVX E;  3K7A E;  1I6H E;  4Q4Z E;  1TWH F;  4C3I F;  4YFX E;  3RZO F;  4C3J E;  3S1M F;  4A3G F;  4A3L F;  4A3D F;  4A3K E;  1TWA E;  4BY7 E;  4XSX E;  5TMC E;  5M5X F;  4G7H E;  2JA6 F;  4C3H F;  1K83 F;  4JK1 E;  2JA5 F;  3GTL E;  3I4N E;  4BY1 E;  3I4M E;  2PMZ H;  4BBS E;  1TWF F;  3GTM E;  3GTK F;  5M5Y F;  2NVX F;  3H0G E;  4A93 E;  2R7Z F;  1I6H F;  3GTO E;  1YNN K;  5FLM E;  2WB1 I;  3GTQ E;  2Y0S H;  1TWA F;  4BY7 F;  4A3K F;  3M4O E;  2NVY E;  4MEY E;  3GTL F;  4A3L E;  4BY1 F;  4LK1 E;  3I4M F;  3I4N F;  5IP7 F;  4QIW H;  4BBS F;  5M5X E;  3GTM F;  2A6E E;  4C3H E;  2NVT E;  5C4J E;  3H0G F;  4A3J E;  4Q5S E;  3GTO F;  4A93 F;  5IYB E;  4Y52 E;  5FLM F;  2R7Z E;  3GTQ F;  2E2J E;  4A3F E;  3DXJ E;  1SFO E;  1IW7 E;  3M4O F;  2BE5 E;  2NVY F;  5BYH E;  1I50 E;  4OIO E;  5C4X E;  2A68 E;  3HKZ K;  5IYD E;  5C4J F;  2NVT F;  4KN7 E;  5M5W E;  2A6H E;  4A3J F;  5IYB F;  4Y52 F;  5IP7 E;  3HOZ F;  3WOD E;  3S16 E;  4AYB K;  2E2J F;  4A3F F;  3HOW E;  1QKL A;  4A3I F;  3PO2 E;  3M3Y E;  1SFO F;  1ZYR E;  4YFK E;  2YU9 F;  1I50 F;  3CQZ E;  5C4X F;  4LJZ E;  5E17 E;  1EIK A;  3S15 E;  3S2D E;  5IYD F;  5M5W F;  1TWG E;  3S1N E;  2PPB E;  3S1R E;  1R9T E;  4A3M F;  4XLN E;  3S16 F;  5IP9 E;  4ZH4 E;  3HOW F;  3PO2 F;  2NVQ E;  3M3Y F;  3HOZ E;  5FJ8 E;  4GZY E;  3H3V G;  3CQZ F;  4A3I E;  2JA7 E;  2KRX A;  4XLP E;  1WCM F;  3HOV E;  3S2D F;  3S15 F;  1SMY E;  2YU9 E;  1I3Q E;  1TWG F;  4YFN E;  3S1N F;  3S1R F;  4YG2 E;  1R9T F;  2WAQ K;  5IP9 F;  2E2I E;  4OIP E;  2E2H E;  2NVQ F;  5FJ8 F;  1TWC F;  4A3M E;  1YNJ K;  1DZF A; 
#chains in the Genus database with same CATH homology
 5M3M E;  5C44 E;  3HOX E;  3HKZ H;  3GTG E;  3S14 E;  2B63 E;  3GTJ E;  4Y7N E;  2VUM E;  1WCM E;  3S2H E;  1Y1V E;  4A3C E;  3RZD E;  5C3E E;  2R92 E;  2WB1 H;  3HOY E;  4BBR E;  4X6A E;  3S1Q E;  3PO3 E;  1TWC E;  3GTP E;  3HOU E;  4A3E E;  4A3B E;  3FKI E;  5M3F E;  5IYC E;  1Y1W E;  2R93 E;  4BXX E;  3S17 E;  4C2M E;  2JA8 E;  1TWH E;  4C3I E;  3H3V F;  3RZO E;  3S1M E;  4A3G E;  4A3D E;  2WAQ H;  2JA6 E;  1K83 E;  2JA5 E;  4AYB H;  1TWF E;  3GTK E;  5M5Y E;  2NVX E;  3K7A E;  1I6H E;  4C3J E;  4A3K E;  1TWA E;  4BY7 E;  3GTL E;  3I4N E;  4BY1 E;  3I4M E;  2PMZ H;  4BBS E;  3GTM E;  3H0G E;  4A93 E;  3GTO E;  5FLM E;  3GTQ E;  2Y0S H;  3M4O E;  2NVY E;  4A3L E;  4QIW H;  5M5X E;  4C3H E;  2NVT E;  5C4J E;  4A3J E;  5IYB E;  4Y52 E;  2R7Z E;  2E2J E;  4A3F E;  1SFO E;  1I50 E;  5C4X E;  5IYD E;  5M5W E;  5IP7 E;  3S16 E;  3HOW E;  3PO2 E;  3M3Y E;  3CQZ E;  1EIK A;  3S15 E;  3S2D E;  1TWG E;  3S1N E;  3S1R E;  1R9T E;  5IP9 E;  2NVQ E;  3HOZ E;  5FJ8 E;  4A3I E;  2JA7 E;  3HOV E;  2YU9 E;  1I3Q E;  2E2I E;  2E2H E;  4A3M E;  1DZF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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