1ITVA

Dimeric form of the haemopexin domain of mmp9
Total Genus 31
20406080100120140160180051015202530
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
195
structure length
195
Chain Sequence
DDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEEPLSKKLFFFSGRQVWVYTGASVLGPRRLDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQFREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCPED

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
3H1 (3-5)TVIII1 (6-9)S2 (18-23)TIV1 (9-12)TI'1 (23-26)S5 (57-60)TIV2 (15-18)AH1 (44-47)TVIII2 (52-55)O1 (4-192)TIV3 (33-36)TII3 (188-191)S4 (39-43)TI1 (48-51)S7 (74-79)S6 (67-71)TII'1 (71-74)3H2 (89-92)S8 (82-88)TI3 (95-98)S11 (119-124)TII'3 (116-119)S14 (151-155)S9 (103-106)S10 (111-116)TII1 (108-111)TIV6 (124-127)AH2 (138-141)S13 (136-137)TI5 (131-134)S12 (129-130)TI4 (125-128)TII2 (142-145)S15 (158-163)TII'4 (163-166)TIV9 (184-187)S16 (166-173)TIV10 (185-188)S17 (176-184)EMPTYS3 (26-30)TIV4 (61-64)TI2 (62-65)S1 (11-15)Updating...
connected with : NaN
molecule tags Hydrolase
source organism Homo sapiens
publication title Structural basis of the adaptive molecular recognition by MMP9.
pubmed doi rcsb
molecule keywords MMP9
total genus 31
structure length 195
sequence length 195
chains with identical sequence B
ec nomenclature ec 3.4.24.35: Gelatinase B.
pdb deposition date 2002-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 1itvA00
1PEXA 2JXYA 1QJSA 1ITVA 3BA0A 1QHUA 3S18A 4FU4A 4LL2A 1SU3A 4RT6B 3OYOA 2MQSA 4YEHA 1GENA 3LP9A 4OEIA 3C7XA 1RTGA 2CLTA 1GXDA 1FBLA 3V6NA 4AUOA 4HSDA 1HXNA 4G0DA 1CK7A 4FVLA
chains in the Genus database with same CATH superfamily
1PEXA 2JXYA 1QJSA 1ITVA 3BA0A 1QHUA 3S18A 4FU4A 4LL2A 1SU3A 4RT6B 3OYOA 2MQSA 4YEHA 1GENA 3LP9A 4OEIA 3C7XA 1RTGA 2CLTA 1GXDA 1FBLA 3V6NA 4AUOA 4HSDA 1HXNA 4G0DA 1CK7A 4FVLA
chains in the Genus database with same CATH topology
1PEXA 2JXYA 1QJSA 1ITVA 3BA0A 1QHUA 3S18A 4FU4A 4LL2A 1SU3A 4RT6B 3OYOA 2MQSA 4YEHA 1GENA 3LP9A 4OEIA 3C7XA 1RTGA 2CLTA 1GXDA 1FBLA 3V6NA 4AUOA 4HSDA 1HXNA 4G0DA 1CK7A 4FVLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PEX A;  2JXY A;  1QJS A;  1ITV A;  3BA0 A;  1QHU A;  3S18 A;  4FU4 A;  4LL2 A;  1SU3 A;  4RT6 B;  3OYO A;  2MQS A;  4YEH A;  1GEN A;  3LP9 A;  4OEI A;  3C7X A;  1RTG A;  2CLT A;  1GXD A;  1FBL A;  3V6N A;  4AUO A;  4HSD A;  1HXN A;  4G0D A;  1CK7 A;  4FVL A; 
#chains in the Genus database with same CATH topology
 1PEX A;  2JXY A;  1QJS A;  1ITV A;  3BA0 A;  1QHU A;  3S18 A;  4FU4 A;  4LL2 A;  1SU3 A;  4RT6 B;  3OYO A;  2MQS A;  4YEH A;  1GEN A;  3LP9 A;  4OEI A;  3C7X A;  1RTG A;  2CLT A;  1GXD A;  1FBL A;  3V6N A;  4AUO A;  4HSD A;  1HXN A;  4G0D A;  1CK7 A;  4FVL A; 
#chains in the Genus database with same CATH homology
 1PEX A;  2JXY A;  1QJS A;  1ITV A;  3BA0 A;  1QHU A;  3S18 A;  4FU4 A;  4LL2 A;  1SU3 A;  4RT6 B;  3OYO A;  2MQS A;  4YEH A;  1GEN A;  3LP9 A;  4OEI A;  3C7X A;  1RTG A;  2CLT A;  1GXD A;  1FBL A;  3V6N A;  4AUO A;  4HSD A;  1HXN A;  4G0D A;  1CK7 A;  4FVL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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