1JV8A

Nmr structure of bpti mutant g37a
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGACRAKRNNFKSAEDCMRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility
pubmed doi rcsb
molecule tags Blood clotting
source organism Bos taurus
molecule keywords TRYPSIN INHIBITOR
total genus 4
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2001-08-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1jv8A00
3LDIA 4DG4C 1YKTB 3AUCA 5JB7A 1P2QB 1G6XA 1T8MB 3AUDA 1BIKA 2FI5I 3BTQI 1OA55 2ODYE 3BTGI 2JOTA 3TPII 1KTHA 4BQDA 1FANA 1T8NB 1YLDB 1DENA 2FTLI 3BYBA 2DDIA 1NAGA 3P95E 1YLCB 1LD5A 4U32X 2LFLA 2CA7A 3UIRC 3LDMA 1JV8A 1P2MB 1KNTA 1TPAI 3D65I 2UUYB 1DEMA 5JB4A 1P2JI 2M99A 1F7ZI 5PTIA 3TGJI 1DTKA 1EJMB 4DTGK 1UUAA 3WNYA 1DTXA 1FAKI 4NTXB 3OFWA 3OTJI 4BNRI 1T8LB 1IRHA 3BTHI 1B0CA 1YC0I 3AUHA 4U30W 1AALA 3FP6I 1KUNA 7PTIA 5JB6A 1LD6A 1BRCI 1SHPA 3AUBA 2M01A 1UUBA 2FTMB 3BTTI 1P2OB 1BPTA 4Y0YI 1BTHP 3BTEI 1OA65 4Y10I 4ISNB 1P2NB 3BTDI 1P2KI 1TFXC 1AAPA 3AUEA 3L33E 1Y62A 2DDJA 3GYMI 8PTIA 2PTCI 1ZR0B 2LFKA 6PTIA 2W8XA 2UUXA 1TOCR 4BD9B 1PITA 1D0DB 5JB5A 3LDJA 4TPII 4Y11I 2FI3I 3L3TE 1K6UA 3BTWI 3M7QB 1ZJDB 2RA3C 1BZXI 4NTWB 1BZ5A 4Y0ZI 1T7CB 5C67C 2TPII 2ZJXA 1BPIA 1CA0D 1TAWB 1BUNB 1TCPA 2TGPI 3BTMI 1ADZA 1T8OB 1CBWD 3CI7A 3TGII 1EAWB 4PTIA 4WWYC 3AUGA 2KCRA 4ISLB 2KNTA 1P2II 3AUIA 3TGKI 2ZVXA 3BTKI 3FP7J 4ISOB 4NTYB 1JV9A 1JC6A 3P92E 2IJOI 2HEXA 4WXVC 3T62D 1KIGI 1QLQA 1D0DA 3UOUB 1MTND 1CO7I 2J6DA 1BRBI 1BTIA 1TAPA 3BTFI 1BF0A 1FY8I 2R9PE 3U1JE 3FP8I 1BHCA 2FI4I 9PTIA 1F5RI 2KAII
chains in the Genus database with same CATH superfamily
3LDIA 4DG4C 1YKTB 3AUCA 5JB7A 1P2QB 1G6XA 1T8MB 3AUDA 1BIKA 2FI5I 3BTQI 1OA55 2ODYE 3BTGI 2JOTA 3TPII 1KTHA 4BQDA 1FANA 1T8NB 1YLDB 1DENA 2FTLI 3BYBA 2DDIA 1NAGA 3P95E 1YLCB 1LD5A 4U32X 2LFLA 2CA7A 3UIRC 3LDMA 1JV8A 1P2MB 1KNTA 1TPAI 3D65I 2UUYB 1DEMA 5JB4A 1P2JI 2M99A 1F7ZI 5PTIA 3TGJI 1DTKA 1EJMB 4DTGK 1UUAA 3WNYA 1DTXA 1FAKI 4NTXB 3OFWA 3OTJI 4BNRI 1T8LB 1IRHA 3BTHI 1B0CA 1YC0I 3AUHA 4U30W 1AALA 3FP6I 1KUNA 7PTIA 5JB6A 1LD6A 1BRCI 1SHPA 3AUBA 2M01A 1UUBA 2FTMB 3BTTI 1P2OB 1BPTA 4Y0YI 1BTHP 3BTEI 1OA65 4Y10I 4ISNB 1P2NB 3BTDI 1P2KI 1TFXC 1AAPA 3AUEA 3L33E 1Y62A 2DDJA 3GYMI 8PTIA 2PTCI 1ZR0B 2LFKA 6PTIA 2W8XA 2UUXA 1TOCR 4BD9B 1PITA 1D0DB 5JB5A 3LDJA 4TPII 4Y11I 2FI3I 3L3TE 1K6UA 3BTWI 3M7QB 1ZJDB 2RA3C 1BZXI 4NTWB 1BZ5A 4Y0ZI 1T7CB 5C67C 2TPII 2ZJXA 1BPIA 1CA0D 1TAWB 1BUNB 1TCPA 2TGPI 3BTMI 1ADZA 1T8OB 1CBWD 3CI7A 3TGII 1EAWB 4PTIA 4WWYC 3AUGA 2KCRA 4ISLB 2KNTA 1P2II 3AUIA 3TGKI 2ZVXA 3BTKI 3FP7J 4ISOB 4NTYB 1JV9A 1JC6A 3P92E 2IJOI 2HEXA 4WXVC 3T62D 1KIGI 1QLQA 1D0DA 3UOUB 1MTND 1CO7I 2J6DA 1BRBI 1BTIA 1TAPA 3BTFI 1BF0A 1FY8I 2R9PE 3U1JE 3FP8I 1BHCA 2FI4I 9PTIA 1F5RI 2KAII
chains in the Genus database with same CATH topology
3LDIA 4DG4C 1YKTB 3AUCA 5JB7A 1P2QB 1G6XA 1T8MB 3AUDA 1BIKA 2FI5I 3BTQI 1OA55 2ODYE 3BTGI 2JOTA 3TPII 1KTHA 4BQDA 1FANA 1T8NB 1YLDB 1DENA 2FTLI 3BYBA 2DDIA 1NAGA 3P95E 1YLCB 1LD5A 4U32X 2LFLA 2CA7A 3UIRC 3LDMA 1JV8A 1P2MB 1KNTA 1TPAI 3D65I 2UUYB 1DEMA 5JB4A 1P2JI 2M99A 1F7ZI 5PTIA 3TGJI 1DTKA 1EJMB 4DTGK 1UUAA 3WNYA 1DTXA 1FAKI 4NTXB 3OFWA 3OTJI 4BNRI 1T8LB 1IRHA 3BTHI 1B0CA 1YC0I 3AUHA 4U30W 1AALA 3FP6I 1KUNA 7PTIA 5JB6A 1LD6A 1BRCI 1SHPA 3AUBA 2M01A 1UUBA 2FTMB 3BTTI 1P2OB 1BPTA 4Y0YI 1BTHP 3BTEI 1OA65 4Y10I 4ISNB 1P2NB 3BTDI 1P2KI 1TFXC 1AAPA 3AUEA 3L33E 1Y62A 2DDJA 3GYMI 8PTIA 2PTCI 1ZR0B 2LFKA 6PTIA 2W8XA 2UUXA 1TOCR 4BD9B 1PITA 1D0DB 5JB5A 3LDJA 4TPII 4Y11I 2FI3I 3L3TE 1K6UA 3BTWI 3M7QB 1ZJDB 2RA3C 1BZXI 4NTWB 1BZ5A 4Y0ZI 1T7CB 5C67C 2TPII 2ZJXA 1BPIA 1CA0D 1TAWB 1BUNB 1TCPA 2TGPI 3BTMI 1ADZA 1T8OB 1CBWD 3CI7A 3TGII 1EAWB 4PTIA 4WWYC 3AUGA 2KCRA 4ISLB 2KNTA 1P2II 3AUIA 3TGKI 2ZVXA 3BTKI 3FP7J 4ISOB 4NTYB 1JV9A 1JC6A 3P92E 2IJOI 2HEXA 4WXVC 3T62D 1KIGI 1QLQA 1D0DA 3UOUB 1MTND 1CO7I 2J6DA 1BRBI 1BTIA 1TAPA 3BTFI 1BF0A 1FY8I 2R9PE 3U1JE 3FP8I 1BHCA 2FI4I 9PTIA 1F5RI 2KAII
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LDI A;  4DG4 C;  1YKT B;  3AUC A;  5JB7 A;  1P2Q B;  1G6X A;  1T8M B;  3AUD A;  1BIK A;  2FI5 I;  3BTQ I;  1OA5 5;  2ODY E;  3BTG I;  2JOT A;  3TPI I;  1KTH A;  4BQD A;  1FAN A;  1T8N B;  1YLD B;  1DEN A;  2FTL I;  3BYB A;  2DDI A;  1NAG A;  3P95 E;  1YLC B;  1LD5 A;  4U32 X;  2LFL A;  2CA7 A;  3UIR C;  3LDM A;  1JV8 A;  1P2M B;  1KNT A;  1TPA I;  3D65 I;  2UUY B;  1DEM A;  5JB4 A;  1P2J I;  2M99 A;  1F7Z I;  5PTI A;  3TGJ I;  1DTK A;  1EJM B;  4DTG K;  1UUA A;  3WNY A;  1DTX A;  1FAK I;  4NTX B;  3OFW A;  3OTJ I;  4BNR I;  1T8L B;  1IRH A;  3BTH I;  1B0C A;  1YC0 I;  3AUH A;  4U30 W;  1AAL A;  3FP6 I;  1KUN A;  7PTI A;  5JB6 A;  1LD6 A;  1BRC I;  1SHP A;  3AUB A;  2M01 A;  1UUB A;  2FTM B;  3BTT I;  1P2O B;  1BPT A;  4Y0Y I;  1BTH P;  3BTE I;  1OA6 5;  4Y10 I;  4ISN B;  1P2N B;  3BTD I;  1P2K I;  1TFX C;  1AAP A;  3AUE A;  3L33 E;  1Y62 A;  2DDJ A;  3GYM I;  8PTI A;  2PTC I;  1ZR0 B;  2LFK A;  6PTI A;  2W8X A;  2UUX A;  1TOC R;  4BD9 B;  1PIT A;  1D0D B;  5JB5 A;  3LDJ A;  4TPI I;  4Y11 I;  2FI3 I;  3L3T E;  1K6U A;  3BTW I;  3M7Q B;  1ZJD B;  2RA3 C;  1BZX I;  4NTW B;  1BZ5 A;  4Y0Z I;  1T7C B;  5C67 C;  2TPI I;  2ZJX A;  1BPI A;  1CA0 D;  1TAW B;  1BUN B;  1TCP A;  2TGP I;  3BTM I;  1ADZ A;  1T8O B;  1CBW D;  3CI7 A;  3TGI I;  1EAW B;  4PTI A;  4WWY C;  3AUG A;  2KCR A;  4ISL B;  2KNT A;  1P2I I;  3AUI A;  3TGK I;  2ZVX A;  3BTK I;  3FP7 J;  4ISO B;  4NTY B;  1JV9 A;  1JC6 A;  3P92 E;  2IJO I;  2HEX A;  4WXV C;  3T62 D;  1KIG I;  1QLQ A;  1D0D A;  3UOU B;  1MTN D;  1CO7 I;  2J6D A;  1BRB I;  1BTI A;  1TAP A;  3BTF I;  1BF0 A;  1FY8 I;  2R9P E;  3U1J E;  3FP8 I;  1BHC A;  2FI4 I;  9PTI A;  1F5R I;  2KAI I; 
#chains in the Genus database with same CATH topology
 3LDI A;  4DG4 C;  1YKT B;  3AUC A;  5JB7 A;  1P2Q B;  1G6X A;  1T8M B;  3AUD A;  1BIK A;  2FI5 I;  3BTQ I;  1OA5 5;  2ODY E;  3BTG I;  2JOT A;  3TPI I;  1KTH A;  4BQD A;  1FAN A;  1T8N B;  1YLD B;  1DEN A;  2FTL I;  3BYB A;  2DDI A;  1NAG A;  3P95 E;  1YLC B;  1LD5 A;  4U32 X;  2LFL A;  2CA7 A;  3UIR C;  3LDM A;  1JV8 A;  1P2M B;  1KNT A;  1TPA I;  3D65 I;  2UUY B;  1DEM A;  5JB4 A;  1P2J I;  2M99 A;  1F7Z I;  5PTI A;  3TGJ I;  1DTK A;  1EJM B;  4DTG K;  1UUA A;  3WNY A;  1DTX A;  1FAK I;  4NTX B;  3OFW A;  3OTJ I;  4BNR I;  1T8L B;  1IRH A;  3BTH I;  1B0C A;  1YC0 I;  3AUH A;  4U30 W;  1AAL A;  3FP6 I;  1KUN A;  7PTI A;  5JB6 A;  1LD6 A;  1BRC I;  1SHP A;  3AUB A;  2M01 A;  1UUB A;  2FTM B;  3BTT I;  1P2O B;  1BPT A;  4Y0Y I;  1BTH P;  3BTE I;  1OA6 5;  4Y10 I;  4ISN B;  1P2N B;  3BTD I;  1P2K I;  1TFX C;  1AAP A;  3AUE A;  3L33 E;  1Y62 A;  2DDJ A;  3GYM I;  8PTI A;  2PTC I;  1ZR0 B;  2LFK A;  6PTI A;  2W8X A;  2UUX A;  1TOC R;  4BD9 B;  1PIT A;  1D0D B;  5JB5 A;  3LDJ A;  4TPI I;  4Y11 I;  2FI3 I;  3L3T E;  1K6U A;  3BTW I;  3M7Q B;  1ZJD B;  2RA3 C;  1BZX I;  4NTW B;  1BZ5 A;  4Y0Z I;  1T7C B;  5C67 C;  2TPI I;  2ZJX A;  1BPI A;  1CA0 D;  1TAW B;  1BUN B;  1TCP A;  2TGP I;  3BTM I;  1ADZ A;  1T8O B;  1CBW D;  3CI7 A;  3TGI I;  1EAW B;  4PTI A;  4WWY C;  3AUG A;  2KCR A;  4ISL B;  2KNT A;  1P2I I;  3AUI A;  3TGK I;  2ZVX A;  3BTK I;  3FP7 J;  4ISO B;  4NTY B;  1JV9 A;  1JC6 A;  3P92 E;  2IJO I;  2HEX A;  4WXV C;  3T62 D;  1KIG I;  1QLQ A;  1D0D A;  3UOU B;  1MTN D;  1CO7 I;  2J6D A;  1BRB I;  1BTI A;  1TAP A;  3BTF I;  1BF0 A;  1FY8 I;  2R9P E;  3U1J E;  3FP8 I;  1BHC A;  2FI4 I;  9PTI A;  1F5R I;  2KAI I; 
#chains in the Genus database with same CATH homology
 3LDI A;  4DG4 C;  1YKT B;  3AUC A;  5JB7 A;  1P2Q B;  1G6X A;  1T8M B;  3AUD A;  1BIK A;  2FI5 I;  3BTQ I;  1OA5 5;  2ODY E;  3BTG I;  2JOT A;  3TPI I;  1KTH A;  4BQD A;  1FAN A;  1T8N B;  1YLD B;  1DEN A;  2FTL I;  3BYB A;  2DDI A;  1NAG A;  3P95 E;  1YLC B;  1LD5 A;  4U32 X;  2LFL A;  2CA7 A;  3UIR C;  3LDM A;  1JV8 A;  1P2M B;  1KNT A;  1TPA I;  3D65 I;  2UUY B;  1DEM A;  5JB4 A;  1P2J I;  2M99 A;  1F7Z I;  5PTI A;  3TGJ I;  1DTK A;  1EJM B;  4DTG K;  1UUA A;  3WNY A;  1DTX A;  1FAK I;  4NTX B;  3OFW A;  3OTJ I;  4BNR I;  1T8L B;  1IRH A;  3BTH I;  1B0C A;  1YC0 I;  3AUH A;  4U30 W;  1AAL A;  3FP6 I;  1KUN A;  7PTI A;  5JB6 A;  1LD6 A;  1BRC I;  1SHP A;  3AUB A;  2M01 A;  1UUB A;  2FTM B;  3BTT I;  1P2O B;  1BPT A;  4Y0Y I;  1BTH P;  3BTE I;  1OA6 5;  4Y10 I;  4ISN B;  1P2N B;  3BTD I;  1P2K I;  1TFX C;  1AAP A;  3AUE A;  3L33 E;  1Y62 A;  2DDJ A;  3GYM I;  8PTI A;  2PTC I;  1ZR0 B;  2LFK A;  6PTI A;  2W8X A;  2UUX A;  1TOC R;  4BD9 B;  1PIT A;  1D0D B;  5JB5 A;  3LDJ A;  4TPI I;  4Y11 I;  2FI3 I;  3L3T E;  1K6U A;  3BTW I;  3M7Q B;  1ZJD B;  2RA3 C;  1BZX I;  4NTW B;  1BZ5 A;  4Y0Z I;  1T7C B;  5C67 C;  2TPI I;  2ZJX A;  1BPI A;  1CA0 D;  1TAW B;  1BUN B;  1TCP A;  2TGP I;  3BTM I;  1ADZ A;  1T8O B;  1CBW D;  3CI7 A;  3TGI I;  1EAW B;  4PTI A;  4WWY C;  3AUG A;  2KCR A;  4ISL B;  2KNT A;  1P2I I;  3AUI A;  3TGK I;  2ZVX A;  3BTK I;  3FP7 J;  4ISO B;  4NTY B;  1JV9 A;  1JC6 A;  3P92 E;  2IJO I;  2HEX A;  4WXV C;  3T62 D;  1KIG I;  1QLQ A;  1D0D A;  3UOU B;  1MTN D;  1CO7 I;  2J6D A;  1BRB I;  1BTI A;  1TAP A;  3BTF I;  1BF0 A;  1FY8 I;  2R9P E;  3U1J E;  3FP8 I;  1BHC A;  2FI4 I;  9PTI A;  1F5R I;  2KAI I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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