1JV8 | Genus

Total Genus 4

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	4
sequence length	58
structure length	58
Chain Sequence	RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGACRAKRNNFKSAEDCMRTCGGA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Blood clotting
source organism	Bos taurus
publication title	A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility pubmed doi rcsb
molecule keywords	TRYPSIN INHIBITOR
total genus	4
structure length	58
sequence length	58
ec nomenclature
pdb deposition date	2001-08-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00014	Kunitz_BPTI	Kunitz/Bovine pancreatic trypsin inhibitor domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
4.10.410.10	Few Secondary Structures	Irregular	Factor Xa Inhibitor	Pancreatic trypsin inhibitor Kunitz domain	1jv8A00

2ODYE 2W8XA 2M99A 1ZR0B 2KCRA 3BTKI 1NAGA 1UUBA 3FP8I 3TPII 5JB4A 3AUEA 1AALA 1KUNA 1ADZA 3M7QB 3OTJI 1P2NB 1TOCR 6PTIA 3UOUB 3AUDA 1P2II 1TPAI 2FI5I 1BHCA 3AUIA 2LFLA 1AAPA 1BZ5A 1LD5A 1T8LB 1BZXI 2J6DA 1G6XA 2FTLI 2HEXA 5C67C 5JB5A 1BTIA 2TGPI 9PTIA 4Y10I 2FI4I 4WWYC 2JOTA 3UIRC 1TAWB 1KIGI 1D0DA 3AUGA 1BTHP 1EAWB 1UUAA 3BTMI 2CA7A 2TPII 1KNTA 8PTIA 1FANA 3BTHI 3P95E 4BNRI 3FP6I 4Y11I 3T62D 4Y0ZI 3BTDI 1LD6A 1OA55 1SHPA 2DDJA 2DDIA 2UUXA 4PTIA 4NTYB 3L3TE 1YLCB 1TFXC 3BTQI 3OFWA 1JV9A 2R9PE 3AUHA 2ZJXA 1DTXA 4NTXB 2KNTA 1T8NB 3BYBA 1JC6A 1TCPA 3D65I 1BRCI 1PITA 1F5RI 2ZVXA 3AUBA 5PTIA 2IJOI 1MTND 1T8OB 2RA3C 3LDJA 1Y62A 1CBWD 1FAKI 1BRBI 1EJMB 1BIKA 3TGII 1IRHA 4BQDA 3P92E 3BTTI 1JV8A 2UUYB 1T8MB 1BUNB 5JB6A 4WXVC 1DEMA 1P2OB 1T7CB 4DG4C 1DENA 1DTKA 1B0CA 1BPTA 4ISLB 1ZJDB 4BD9B 2M01A 3AUCA 3BTGI 3WNYA 3GYMI 4NTWB 4TPII 7PTIA 1K6UA 2FI3I 1BPIA 2FTMB 3LDMA 1P2KI 1YC0I 2LFKA 1KTHA 3FP7J 3LDIA 4U30W 3TGKI 3TGJI 1P2JI 3CI7A 1FY8I 3U1JE 1TAPA 1BF0A 5JB7A 1D0DB 1P2QB 3BTEI 4DTGK 3L33E 1CA0D 4U32X 1YKTB 2PTCI 1OA65 1F7ZI 1P2MB 4Y0YI 4ISOB 3BTWI 2KAII 1YLDB 4ISNB 1CO7I 3BTFI 1QLQA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2ODY E;  2W8X A;  2M99 A;  1ZR0 B;  2KCR A;  3BTK I;  1NAG A;  1UUB A;  3FP8 I;  3TPI I;  5JB4 A;  3AUE A;  1AAL A;  1KUN A;  1ADZ A;  3M7Q B;  3OTJ I;  1P2N B;  1TOC R;  6PTI A;  3UOU B;  3AUD A;  1P2I I;  1TPA I;  2FI5 I;  1BHC A;  3AUI A;  2LFL A;  1AAP A;  1BZ5 A;  1LD5 A;  1T8L B;  1BZX I;  2J6D A;  1G6X A;  2FTL I;  2HEX A;  5C67 C;  5JB5 A;  1BTI A;  2TGP I;  9PTI A;  4Y10 I;  2FI4 I;  4WWY C;  2JOT A;  3UIR C;  1TAW B;  1KIG I;  1D0D A;  3AUG A;  1BTH P;  1EAW B;  1UUA A;  3BTM I;  2CA7 A;  2TPI I;  1KNT A;  8PTI A;  1FAN A;  3BTH I;  3P95 E;  4BNR I;  3FP6 I;  4Y11 I;  3T62 D;  4Y0Z I;  3BTD I;  1LD6 A;  1OA5 5;  1SHP A;  2DDJ A;  2DDI A;  2UUX A;  4PTI A;  4NTY B;  3L3T E;  1YLC B;  1TFX C;  3BTQ I;  3OFW A;  1JV9 A;  2R9P E;  3AUH A;  2ZJX A;  1DTX A;  4NTX B;  2KNT A;  1T8N B;  3BYB A;  1JC6 A;  1TCP A;  3D65 I;  1BRC I;  1PIT A;  1F5R I;  2ZVX A;  3AUB A;  5PTI A;  2IJO I;  1MTN D;  1T8O B;  2RA3 C;  3LDJ A;  1Y62 A;  1CBW D;  1FAK I;  1BRB I;  1EJM B;  1BIK A;  3TGI I;  1IRH A;  4BQD A;  3P92 E;  3BTT I;  1JV8 A;  2UUY B;  1T8M B;  1BUN B;  5JB6 A;  4WXV C;  1DEM A;  1P2O B;  1T7C B;  4DG4 C;  1DEN A;  1DTK A;  1B0C A;  1BPT A;  4ISL B;  1ZJD B;  4BD9 B;  2M01 A;  3AUC A;  3BTG I;  3WNY A;  3GYM I;  4NTW B;  4TPI I;  7PTI A;  1K6U A;  2FI3 I;  1BPI A;  2FTM B;  3LDM A;  1P2K I;  1YC0 I;  2LFK A;  1KTH A;  3FP7 J;  3LDI A;  4U30 W;  3TGK I;  3TGJ I;  1P2J I;  3CI7 A;  1FY8 I;  3U1J E;  1TAP A;  1BF0 A;  5JB7 A;  1D0D B;  1P2Q B;  3BTE I;  4DTG K;  3L33 E;  1CA0 D;  4U32 X;  1YKT B;  2PTC I;  1OA6 5;  1F7Z I;  1P2M B;  4Y0Y I;  4ISO B;  3BTW I;  2KAI I;  1YLD B;  4ISN B;  1CO7 I;  3BTF I;  1QLQ A; 
#chains in the Genus database with same CATH topology
 2ODY E;  2W8X A;  2M99 A;  1ZR0 B;  2KCR A;  3BTK I;  1NAG A;  1UUB A;  3FP8 I;  3TPI I;  5JB4 A;  3AUE A;  1AAL A;  1KUN A;  1ADZ A;  3M7Q B;  3OTJ I;  1P2N B;  1TOC R;  6PTI A;  3UOU B;  3AUD A;  1P2I I;  1TPA I;  2FI5 I;  1BHC A;  3AUI A;  2LFL A;  1AAP A;  1BZ5 A;  1LD5 A;  1T8L B;  1BZX I;  2J6D A;  1G6X A;  2FTL I;  2HEX A;  5C67 C;  5JB5 A;  1BTI A;  2TGP I;  9PTI A;  4Y10 I;  2FI4 I;  4WWY C;  2JOT A;  3UIR C;  1TAW B;  1KIG I;  1D0D A;  3AUG A;  1BTH P;  1EAW B;  1UUA A;  3BTM I;  2CA7 A;  2TPI I;  1KNT A;  8PTI A;  1FAN A;  3BTH I;  3P95 E;  4BNR I;  3FP6 I;  4Y11 I;  3T62 D;  4Y0Z I;  3BTD I;  1LD6 A;  1OA5 5;  1SHP A;  2DDJ A;  2DDI A;  2UUX A;  4PTI A;  4NTY B;  3L3T E;  1YLC B;  1TFX C;  3BTQ I;  3OFW A;  1JV9 A;  2R9P E;  3AUH A;  2ZJX A;  1DTX A;  4NTX B;  2KNT A;  1T8N B;  3BYB A;  1JC6 A;  1TCP A;  3D65 I;  1BRC I;  1PIT A;  1F5R I;  2ZVX A;  3AUB A;  5PTI A;  2IJO I;  1MTN D;  1T8O B;  2RA3 C;  3LDJ A;  1Y62 A;  1CBW D;  1FAK I;  1BRB I;  1EJM B;  1BIK A;  3TGI I;  1IRH A;  4BQD A;  3P92 E;  3BTT I;  1JV8 A;  2UUY B;  1T8M B;  1BUN B;  5JB6 A;  4WXV C;  1DEM A;  1P2O B;  1T7C B;  4DG4 C;  1DEN A;  1DTK A;  1B0C A;  1BPT A;  4ISL B;  1ZJD B;  4BD9 B;  2M01 A;  3AUC A;  3BTG I;  3WNY A;  3GYM I;  4NTW B;  4TPI I;  7PTI A;  1K6U A;  2FI3 I;  1BPI A;  2FTM B;  3LDM A;  1P2K I;  1YC0 I;  2LFK A;  1KTH A;  3FP7 J;  3LDI A;  4U30 W;  3TGK I;  3TGJ I;  1P2J I;  3CI7 A;  1FY8 I;  3U1J E;  1TAP A;  1BF0 A;  5JB7 A;  1D0D B;  1P2Q B;  3BTE I;  4DTG K;  3L33 E;  1CA0 D;  4U32 X;  1YKT B;  2PTC I;  1OA6 5;  1F7Z I;  1P2M B;  4Y0Y I;  4ISO B;  3BTW I;  2KAI I;  1YLD B;  4ISN B;  1CO7 I;  3BTF I;  1QLQ A; 
#chains in the Genus database with same CATH homology
 2ODY E;  2W8X A;  2M99 A;  1ZR0 B;  2KCR A;  3BTK I;  1NAG A;  1UUB A;  3FP8 I;  3TPI I;  5JB4 A;  3AUE A;  1AAL A;  1KUN A;  1ADZ A;  3M7Q B;  3OTJ I;  1P2N B;  1TOC R;  6PTI A;  3UOU B;  3AUD A;  1P2I I;  1TPA I;  2FI5 I;  1BHC A;  3AUI A;  2LFL A;  1AAP A;  1BZ5 A;  1LD5 A;  1T8L B;  1BZX I;  2J6D A;  1G6X A;  2FTL I;  2HEX A;  5C67 C;  5JB5 A;  1BTI A;  2TGP I;  9PTI A;  4Y10 I;  2FI4 I;  4WWY C;  2JOT A;  3UIR C;  1TAW B;  1KIG I;  1D0D A;  3AUG A;  1BTH P;  1EAW B;  1UUA A;  3BTM I;  2CA7 A;  2TPI I;  1KNT A;  8PTI A;  1FAN A;  3BTH I;  3P95 E;  4BNR I;  3FP6 I;  4Y11 I;  3T62 D;  4Y0Z I;  3BTD I;  1LD6 A;  1OA5 5;  1SHP A;  2DDJ A;  2DDI A;  2UUX A;  4PTI A;  4NTY B;  3L3T E;  1YLC B;  1TFX C;  3BTQ I;  3OFW A;  1JV9 A;  2R9P E;  3AUH A;  2ZJX A;  1DTX A;  4NTX B;  2KNT A;  1T8N B;  3BYB A;  1JC6 A;  1TCP A;  3D65 I;  1BRC I;  1PIT A;  1F5R I;  2ZVX A;  3AUB A;  5PTI A;  2IJO I;  1MTN D;  1T8O B;  2RA3 C;  3LDJ A;  1Y62 A;  1CBW D;  1FAK I;  1BRB I;  1EJM B;  1BIK A;  3TGI I;  1IRH A;  4BQD A;  3P92 E;  3BTT I;  1JV8 A;  2UUY B;  1T8M B;  1BUN B;  5JB6 A;  4WXV C;  1DEM A;  1P2O B;  1T7C B;  4DG4 C;  1DEN A;  1DTK A;  1B0C A;  1BPT A;  4ISL B;  1ZJD B;  4BD9 B;  2M01 A;  3AUC A;  3BTG I;  3WNY A;  3GYM I;  4NTW B;  4TPI I;  7PTI A;  1K6U A;  2FI3 I;  1BPI A;  2FTM B;  3LDM A;  1P2K I;  1YC0 I;  2LFK A;  1KTH A;  3FP7 J;  3LDI A;  4U30 W;  3TGK I;  3TGJ I;  1P2J I;  3CI7 A;  1FY8 I;  3U1J E;  1TAP A;  1BF0 A;  5JB7 A;  1D0D B;  1P2Q B;  3BTE I;  4DTG K;  3L33 E;  1CA0 D;  4U32 X;  1YKT B;  2PTC I;  1OA6 5;  1F7Z I;  1P2M B;  4Y0Y I;  4ISO B;  3BTW I;  2KAI I;  1YLD B;  4ISN B;  1CO7 I;  3BTF I;  1QLQ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1JV8A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations