1JV9A

Nmr structure of bpti mutant g37a
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGACRAKRNNFKSAEDCMRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility
pubmed doi rcsb
molecule tags Blood clotting
source organism Bos taurus
molecule keywords TRYPSIN INHIBITOR
total genus 3
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2001-08-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1jv9A00
1DTKA 4DTGK 3TGKI 1FANA 3BTMI 1BZXI 4Y0ZI 1AALA 8PTIA 1P2NB 2KAII 1IRHA 3AUCA 3AUDA 1T8LB 1YLCB 4U30W 2FTMB 1DENA 1UUAA 1EJMB 3FP6I 2ODYE 1P2KI 1ZR0B 1BZ5A 1OA65 1BHCA 1TFXC 4ISOB 1YLDB 2FI5I 4ISLB 1F5RI 2PTCI 4DG4C 9PTIA 4NTWB 1TOCR 2ZJXA 3BTFI 1P2JI 2CA7A 1BPIA 1B0CA 1T8NB 1G6XA 3BTTI 4U32X 2R9PE 3BYBA 3FP7J 1F7ZI 3T62D 1Y62A 3UIRC 3L33E 1BRCI 3UOUB 3P92E 2HEXA 4ISNB 2JOTA 1P2OB 1CO7I 5JB6A 1ZJDB 2ZVXA 1D0DA 3LDJA 1QLQA 1JV9A 1CBWD 2W8XA 1TCPA 1CA0D 3BTKI 4BNRI 2TPII 2DDIA 2FI4I 3BTHI 2UUYB 3P95E 1P2QB 1LD5A 1TPAI 3LDMA 1JC6A 2FTLI 3BTDI 3TGJI 5JB5A 2KNTA 3CI7A 1P2II 1PITA 1OA55 3AUHA 3M7QB 3AUIA 1T7CB 1D0DB 1FY8I 4PTIA 4WXVC 5JB7A 2RA3C 2FI3I 3OFWA 5PTIA 4WWYC 4BD9B 1NAGA 2LFLA 1BIKA 3AUEA 1MTND 1DTXA 2M01A 2KCRA 2DDJA 1BTIA 4Y11I 3AUBA 3TGII 2LFKA 1JV8A 2UUXA 6PTIA 3BTQI 2J6DA 2TGPI 1EAWB 1DEMA 3FP8I 4BQDA 1BTHP 1TAPA 3WNYA 2M99A 7PTIA 3LDIA 3L3TE 1KIGI 1K6UA 1YKTB 4NTXB 1BUNB 1P2MB 1T8MB 4NTYB 1TAWB 3BTWI 3OTJI 3AUGA 1YC0I 1BF0A 5C67C 3D65I 1BPTA 3BTGI 2IJOI 3BTEI 1UUBA 5JB4A 4TPII 4Y10I 3GYMI 1BRBI 1AAPA 1SHPA 4Y0YI 1KUNA 1KNTA 1T8OB 1FAKI 1KTHA 3TPII 1LD6A 1ADZA 3U1JE
chains in the Genus database with same CATH superfamily
1DTKA 4DTGK 3TGKI 1FANA 3BTMI 1BZXI 4Y0ZI 1AALA 8PTIA 1P2NB 2KAII 1IRHA 3AUCA 3AUDA 1T8LB 1YLCB 4U30W 2FTMB 1DENA 1UUAA 1EJMB 3FP6I 2ODYE 1P2KI 1ZR0B 1BZ5A 1OA65 1BHCA 1TFXC 4ISOB 1YLDB 2FI5I 4ISLB 1F5RI 2PTCI 4DG4C 9PTIA 4NTWB 1TOCR 2ZJXA 3BTFI 1P2JI 2CA7A 1BPIA 1B0CA 1T8NB 1G6XA 3BTTI 4U32X 2R9PE 3BYBA 3FP7J 1F7ZI 3T62D 1Y62A 3UIRC 3L33E 1BRCI 3UOUB 3P92E 2HEXA 4ISNB 2JOTA 1P2OB 1CO7I 5JB6A 1ZJDB 2ZVXA 1D0DA 3LDJA 1QLQA 1JV9A 1CBWD 2W8XA 1TCPA 1CA0D 3BTKI 4BNRI 2TPII 2DDIA 2FI4I 3BTHI 2UUYB 3P95E 1P2QB 1LD5A 1TPAI 3LDMA 1JC6A 2FTLI 3BTDI 3TGJI 5JB5A 2KNTA 3CI7A 1P2II 1PITA 1OA55 3AUHA 3M7QB 3AUIA 1T7CB 1D0DB 1FY8I 4PTIA 4WXVC 5JB7A 2RA3C 2FI3I 3OFWA 5PTIA 4WWYC 4BD9B 1NAGA 2LFLA 1BIKA 3AUEA 1MTND 1DTXA 2M01A 2KCRA 2DDJA 1BTIA 4Y11I 3AUBA 3TGII 2LFKA 1JV8A 2UUXA 6PTIA 3BTQI 2J6DA 2TGPI 1EAWB 1DEMA 3FP8I 4BQDA 1BTHP 1TAPA 3WNYA 2M99A 7PTIA 3LDIA 3L3TE 1KIGI 1K6UA 1YKTB 4NTXB 1BUNB 1P2MB 1T8MB 4NTYB 1TAWB 3BTWI 3OTJI 3AUGA 1YC0I 1BF0A 5C67C 3D65I 1BPTA 3BTGI 2IJOI 3BTEI 1UUBA 5JB4A 4TPII 4Y10I 3GYMI 1BRBI 1AAPA 1SHPA 4Y0YI 1KUNA 1KNTA 1T8OB 1FAKI 1KTHA 3TPII 1LD6A 1ADZA 3U1JE
chains in the Genus database with same CATH topology
1DTKA 4DTGK 3TGKI 1FANA 3BTMI 1BZXI 4Y0ZI 1AALA 8PTIA 1P2NB 2KAII 1IRHA 3AUCA 3AUDA 1T8LB 1YLCB 4U30W 2FTMB 1DENA 1UUAA 1EJMB 3FP6I 2ODYE 1P2KI 1ZR0B 1BZ5A 1OA65 1BHCA 1TFXC 4ISOB 1YLDB 2FI5I 4ISLB 1F5RI 2PTCI 4DG4C 9PTIA 4NTWB 1TOCR 2ZJXA 3BTFI 1P2JI 2CA7A 1BPIA 1B0CA 1T8NB 1G6XA 3BTTI 4U32X 2R9PE 3BYBA 3FP7J 1F7ZI 3T62D 1Y62A 3UIRC 3L33E 1BRCI 3UOUB 3P92E 2HEXA 4ISNB 2JOTA 1P2OB 1CO7I 5JB6A 1ZJDB 2ZVXA 1D0DA 3LDJA 1QLQA 1JV9A 1CBWD 2W8XA 1TCPA 1CA0D 3BTKI 4BNRI 2TPII 2DDIA 2FI4I 3BTHI 2UUYB 3P95E 1P2QB 1LD5A 1TPAI 3LDMA 1JC6A 2FTLI 3BTDI 3TGJI 5JB5A 2KNTA 3CI7A 1P2II 1PITA 1OA55 3AUHA 3M7QB 3AUIA 1T7CB 1D0DB 1FY8I 4PTIA 4WXVC 5JB7A 2RA3C 2FI3I 3OFWA 5PTIA 4WWYC 4BD9B 1NAGA 2LFLA 1BIKA 3AUEA 1MTND 1DTXA 2M01A 2KCRA 2DDJA 1BTIA 4Y11I 3AUBA 3TGII 2LFKA 1JV8A 2UUXA 6PTIA 3BTQI 2J6DA 2TGPI 1EAWB 1DEMA 3FP8I 4BQDA 1BTHP 1TAPA 3WNYA 2M99A 7PTIA 3LDIA 3L3TE 1KIGI 1K6UA 1YKTB 4NTXB 1BUNB 1P2MB 1T8MB 4NTYB 1TAWB 3BTWI 3OTJI 3AUGA 1YC0I 1BF0A 5C67C 3D65I 1BPTA 3BTGI 2IJOI 3BTEI 1UUBA 5JB4A 4TPII 4Y10I 3GYMI 1BRBI 1AAPA 1SHPA 4Y0YI 1KUNA 1KNTA 1T8OB 1FAKI 1KTHA 3TPII 1LD6A 1ADZA 3U1JE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DTK A;  4DTG K;  3TGK I;  1FAN A;  3BTM I;  1BZX I;  4Y0Z I;  1AAL A;  8PTI A;  1P2N B;  2KAI I;  1IRH A;  3AUC A;  3AUD A;  1T8L B;  1YLC B;  4U30 W;  2FTM B;  1DEN A;  1UUA A;  1EJM B;  3FP6 I;  2ODY E;  1P2K I;  1ZR0 B;  1BZ5 A;  1OA6 5;  1BHC A;  1TFX C;  4ISO B;  1YLD B;  2FI5 I;  4ISL B;  1F5R I;  2PTC I;  4DG4 C;  9PTI A;  4NTW B;  1TOC R;  2ZJX A;  3BTF I;  1P2J I;  2CA7 A;  1BPI A;  1B0C A;  1T8N B;  1G6X A;  3BTT I;  4U32 X;  2R9P E;  3BYB A;  3FP7 J;  1F7Z I;  3T62 D;  1Y62 A;  3UIR C;  3L33 E;  1BRC I;  3UOU B;  3P92 E;  2HEX A;  4ISN B;  2JOT A;  1P2O B;  1CO7 I;  5JB6 A;  1ZJD B;  2ZVX A;  1D0D A;  3LDJ A;  1QLQ A;  1JV9 A;  1CBW D;  2W8X A;  1TCP A;  1CA0 D;  3BTK I;  4BNR I;  2TPI I;  2DDI A;  2FI4 I;  3BTH I;  2UUY B;  3P95 E;  1P2Q B;  1LD5 A;  1TPA I;  3LDM A;  1JC6 A;  2FTL I;  3BTD I;  3TGJ I;  5JB5 A;  2KNT A;  3CI7 A;  1P2I I;  1PIT A;  1OA5 5;  3AUH A;  3M7Q B;  3AUI A;  1T7C B;  1D0D B;  1FY8 I;  4PTI A;  4WXV C;  5JB7 A;  2RA3 C;  2FI3 I;  3OFW A;  5PTI A;  4WWY C;  4BD9 B;  1NAG A;  2LFL A;  1BIK A;  3AUE A;  1MTN D;  1DTX A;  2M01 A;  2KCR A;  2DDJ A;  1BTI A;  4Y11 I;  3AUB A;  3TGI I;  2LFK A;  1JV8 A;  2UUX A;  6PTI A;  3BTQ I;  2J6D A;  2TGP I;  1EAW B;  1DEM A;  3FP8 I;  4BQD A;  1BTH P;  1TAP A;  3WNY A;  2M99 A;  7PTI A;  3LDI A;  3L3T E;  1KIG I;  1K6U A;  1YKT B;  4NTX B;  1BUN B;  1P2M B;  1T8M B;  4NTY B;  1TAW B;  3BTW I;  3OTJ I;  3AUG A;  1YC0 I;  1BF0 A;  5C67 C;  3D65 I;  1BPT A;  3BTG I;  2IJO I;  3BTE I;  1UUB A;  5JB4 A;  4TPI I;  4Y10 I;  3GYM I;  1BRB I;  1AAP A;  1SHP A;  4Y0Y I;  1KUN A;  1KNT A;  1T8O B;  1FAK I;  1KTH A;  3TPI I;  1LD6 A;  1ADZ A;  3U1J E; 
#chains in the Genus database with same CATH topology
 1DTK A;  4DTG K;  3TGK I;  1FAN A;  3BTM I;  1BZX I;  4Y0Z I;  1AAL A;  8PTI A;  1P2N B;  2KAI I;  1IRH A;  3AUC A;  3AUD A;  1T8L B;  1YLC B;  4U30 W;  2FTM B;  1DEN A;  1UUA A;  1EJM B;  3FP6 I;  2ODY E;  1P2K I;  1ZR0 B;  1BZ5 A;  1OA6 5;  1BHC A;  1TFX C;  4ISO B;  1YLD B;  2FI5 I;  4ISL B;  1F5R I;  2PTC I;  4DG4 C;  9PTI A;  4NTW B;  1TOC R;  2ZJX A;  3BTF I;  1P2J I;  2CA7 A;  1BPI A;  1B0C A;  1T8N B;  1G6X A;  3BTT I;  4U32 X;  2R9P E;  3BYB A;  3FP7 J;  1F7Z I;  3T62 D;  1Y62 A;  3UIR C;  3L33 E;  1BRC I;  3UOU B;  3P92 E;  2HEX A;  4ISN B;  2JOT A;  1P2O B;  1CO7 I;  5JB6 A;  1ZJD B;  2ZVX A;  1D0D A;  3LDJ A;  1QLQ A;  1JV9 A;  1CBW D;  2W8X A;  1TCP A;  1CA0 D;  3BTK I;  4BNR I;  2TPI I;  2DDI A;  2FI4 I;  3BTH I;  2UUY B;  3P95 E;  1P2Q B;  1LD5 A;  1TPA I;  3LDM A;  1JC6 A;  2FTL I;  3BTD I;  3TGJ I;  5JB5 A;  2KNT A;  3CI7 A;  1P2I I;  1PIT A;  1OA5 5;  3AUH A;  3M7Q B;  3AUI A;  1T7C B;  1D0D B;  1FY8 I;  4PTI A;  4WXV C;  5JB7 A;  2RA3 C;  2FI3 I;  3OFW A;  5PTI A;  4WWY C;  4BD9 B;  1NAG A;  2LFL A;  1BIK A;  3AUE A;  1MTN D;  1DTX A;  2M01 A;  2KCR A;  2DDJ A;  1BTI A;  4Y11 I;  3AUB A;  3TGI I;  2LFK A;  1JV8 A;  2UUX A;  6PTI A;  3BTQ I;  2J6D A;  2TGP I;  1EAW B;  1DEM A;  3FP8 I;  4BQD A;  1BTH P;  1TAP A;  3WNY A;  2M99 A;  7PTI A;  3LDI A;  3L3T E;  1KIG I;  1K6U A;  1YKT B;  4NTX B;  1BUN B;  1P2M B;  1T8M B;  4NTY B;  1TAW B;  3BTW I;  3OTJ I;  3AUG A;  1YC0 I;  1BF0 A;  5C67 C;  3D65 I;  1BPT A;  3BTG I;  2IJO I;  3BTE I;  1UUB A;  5JB4 A;  4TPI I;  4Y10 I;  3GYM I;  1BRB I;  1AAP A;  1SHP A;  4Y0Y I;  1KUN A;  1KNT A;  1T8O B;  1FAK I;  1KTH A;  3TPI I;  1LD6 A;  1ADZ A;  3U1J E; 
#chains in the Genus database with same CATH homology
 1DTK A;  4DTG K;  3TGK I;  1FAN A;  3BTM I;  1BZX I;  4Y0Z I;  1AAL A;  8PTI A;  1P2N B;  2KAI I;  1IRH A;  3AUC A;  3AUD A;  1T8L B;  1YLC B;  4U30 W;  2FTM B;  1DEN A;  1UUA A;  1EJM B;  3FP6 I;  2ODY E;  1P2K I;  1ZR0 B;  1BZ5 A;  1OA6 5;  1BHC A;  1TFX C;  4ISO B;  1YLD B;  2FI5 I;  4ISL B;  1F5R I;  2PTC I;  4DG4 C;  9PTI A;  4NTW B;  1TOC R;  2ZJX A;  3BTF I;  1P2J I;  2CA7 A;  1BPI A;  1B0C A;  1T8N B;  1G6X A;  3BTT I;  4U32 X;  2R9P E;  3BYB A;  3FP7 J;  1F7Z I;  3T62 D;  1Y62 A;  3UIR C;  3L33 E;  1BRC I;  3UOU B;  3P92 E;  2HEX A;  4ISN B;  2JOT A;  1P2O B;  1CO7 I;  5JB6 A;  1ZJD B;  2ZVX A;  1D0D A;  3LDJ A;  1QLQ A;  1JV9 A;  1CBW D;  2W8X A;  1TCP A;  1CA0 D;  3BTK I;  4BNR I;  2TPI I;  2DDI A;  2FI4 I;  3BTH I;  2UUY B;  3P95 E;  1P2Q B;  1LD5 A;  1TPA I;  3LDM A;  1JC6 A;  2FTL I;  3BTD I;  3TGJ I;  5JB5 A;  2KNT A;  3CI7 A;  1P2I I;  1PIT A;  1OA5 5;  3AUH A;  3M7Q B;  3AUI A;  1T7C B;  1D0D B;  1FY8 I;  4PTI A;  4WXV C;  5JB7 A;  2RA3 C;  2FI3 I;  3OFW A;  5PTI A;  4WWY C;  4BD9 B;  1NAG A;  2LFL A;  1BIK A;  3AUE A;  1MTN D;  1DTX A;  2M01 A;  2KCR A;  2DDJ A;  1BTI A;  4Y11 I;  3AUB A;  3TGI I;  2LFK A;  1JV8 A;  2UUX A;  6PTI A;  3BTQ I;  2J6D A;  2TGP I;  1EAW B;  1DEM A;  3FP8 I;  4BQD A;  1BTH P;  1TAP A;  3WNY A;  2M99 A;  7PTI A;  3LDI A;  3L3T E;  1KIG I;  1K6U A;  1YKT B;  4NTX B;  1BUN B;  1P2M B;  1T8M B;  4NTY B;  1TAW B;  3BTW I;  3OTJ I;  3AUG A;  1YC0 I;  1BF0 A;  5C67 C;  3D65 I;  1BPT A;  3BTG I;  2IJO I;  3BTE I;  1UUB A;  5JB4 A;  4TPI I;  4Y10 I;  3GYM I;  1BRB I;  1AAP A;  1SHP A;  4Y0Y I;  1KUN A;  1KNT A;  1T8O B;  1FAK I;  1KTH A;  3TPI I;  1LD6 A;  1ADZ A;  3U1J E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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