1K83F

Crystal structure of yeast rna polymerase ii complexed with the inhibitor alpha amanitin
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Transcription: Alpha-Amanitin-RNA Polymerase II Cocrystal at 2.8 A Resolution.
pubmed doi rcsb
molecule tags Transcription/toxin
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 23
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2001-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1k83F00
5FJ8F 2O5IE 4Q5SE 4A3DF 1I50F 3HOZF 4JK1E 1I3QF 3GTMF 3S1QF 4YFKE 3S17F 1TWHF 4XLPE 1Y1WF 3S16F 1YNNK 4C3HF 2CW0E 4A3JF 2YU9F 1IW7E 2PPBE 4LJZE 4C3JF 2JA8F 1I6HF 4X6AF 2R92F 3WODE 3EQLE 4MEXE 3M4OF 4A3IF 3K7AF 1I6VE 1TWGF 2NVQF 3H0GF 2E2HF 5IPLE 4LLGE 3HOVF 4OIRE 2NVYF 3HKZK 3RZOF 4KMUE 1K83F 5M5XF 4C2MF 3HOXF 1SMYE 2PMZK 4Q4ZE 3S14F 4Y7NF 3S1MF 2JA6F 3H3VG 5IP9F 4BXXF 3S1RF 1HQME 4C3IF 1R9TF 3GTJF 4MQ9E 4A3EF 2A68E 2R93F 3GTPF 4A3KF 3PO2F 5TMFE 5M5YF 2JA5F 4GZYE 2Y0SI 2VUMF 2WAQK 3S2DF 5BYHE 5C4JF 1ZYRE 2E2IF 4A3LF 1WCMF 4BY1F 3RZDF 3GTKF 5M5WF 2NVXF 3M3YF 3S2HF 3GTGF 3HOWF 5TMCE 5IYBF 4LK1E 3CQZF 4OINE 1SFOF 2B63F 4A3GF 1TWCF 2E2JF 3HOUF 3S15F 2A69E 2WB1I 4A3MF 4A93F 2JA7F 3GTQF 4MEYE 1Y1VF 4YFXE 5IYCF 1TWFF 4OIPE 5E17E 5D4EE 4XLNE 3I4MF 4G7HE 1YNJK 3I4NF 2NVTF 3DXJE 3GTOF 4A3BF 4G7OE 3HOYF 4XSXE 5D4DE 3FKIF 4LK0E 4AYBK 1QKLA 4OIQE 5C44F 2BE5E 4XSZE 2R7ZF 3PO3F 1TWAF 5C3EF 3GTLF 4A3FF 2O5JE 4YG2E 4G7ZE 5D4CE 4KN4E 4BBRF 4YFNE 3S1NF 4Y52F 5C4XF 4OIOE 4KN7E 4BBSF 5IP7F 5FLMF 4A3CF 4ZH4E 2A6HE 5M3MF 5E18E 5IYDF 2A6EE 4BY7F 5M3FF
chains in the Genus database with same CATH superfamily
4BBSE 5FJ8F 2O5IE 4Q5SE 5IP7E 5FLME 4A3DF 1I50F 4A3CE 3HOZF 4JK1E 1I3QF 3GTMF 5IYDE 5M3ME 4YFKE 3H3VF 3S2HF 3S17F 3S1QF 4BY7E 5M3FE 1TWHF 4XLPE 1Y1WF 2PMZH 3S16F 5FJ8E 1YNNK 1K83E 4A3DE 4C3HF 1I50E 3HOZE 2CW0E 4A3JF 1I3QE 2YU9F 3GTME 1IW7E 2PPBE 4LJZE 4C3JF 2JA8F 1I6HF 3S17E 2R92F 3WODE 3S1QE 1TWHE 3EQLE 4MEXE 3M4OF 3M3YE 5IP9E 3K7AF 1I6VE 4A3IF 1TWGF 1Y1WE 2WAQH 3H0GF 2NVQF 2E2HF 3S16E 3GTJE 5IPLE 4LLGE 3HOVF 4C3HE 4OIRE 4A3KE 2NVYF 3HKZK 4A3JE 2YU9E 4X6AF 2JA8E 4KMUE 3RZOF 4C3JE 2VUME 1I6HE 4X6AE 2R92E 3M4OE 1K83F 1EIKA 4A3IE 3K7AE 1TWGE 5M5XF 4C2MF 2NVQE 3H0GE 2E2HE 3HOXF 1SMYE 2PMZK 4Q4ZE 3S14F 3HOVE 4Y7NF 3S1MF 2JA6F 3H3VG 4QIWK 2NVYE 5IP9F 4BXXF 3S1RF 3RZOE 1HQME 4C3IF 1R9TF 3GTJF 4A3GE 4MQ9E 4A3EF 2A68E 1DZFA 2R93F 3GTPF 2KRXA 4A3KF 5M5XE 5TMFE 4C2ME 5M5YF 3PO2F 3HOXE 3S14E 2JA5F 4GZYE 2Y0SI 2VUMF 2WAQK 3S2DF 5BYHE 4Y7NE 3S1ME 5C4JF 1ZYRE 2JA6E 4BXXE 2E2IF 3S1RE 4A3LF 5C4XE 1WCMF 4BY1F 4C3IE 3RZDF 5M5WF 1R9TE 2NVXF 4A3EE 2NVTE 3GTKF 3GTGF 3HOWF 3M3YF 5TMCE 3GTPE 2R93E 3PO2E 5IYBF 4LK1E 5M5YE 3CQZF 4AYBH 1SFOF 4OINE 2JA5E 2B63F 3S2DE 4A3GF 1TWCF 2E2JF 5C4JE 3HOUF 2A69E 3S15F 2E2IE 4A3LE 2WB1I 4A3MF 4A93F 2JA7F 3GTQF 1WCME 4BY1E 4MEYE 1Y1VF 4YFXE 5M5WE 5IYCF 1TWFF 4OIPE 3RZDE 5D4EE 2NVXE 3GTGE 3HOWE 3S2HE 5E17E 5IYBE 3CQZE 4XLNE 1SFOE 3I4MF 2B63E 4G7HE 1YNJK 1TWCE 3I4NF 2NVTF 2E2JE 3HOUE 3S15E 3DXJE 4A3ME 3GTOF 4A93E 2JA7E 3GTQE 4A3BF 4G7OE 3HOYF 4XSXE 1Y1VE 5IYCE 1TWFE 5D4DE 3I4ME 3FKIF 4LK0E 4AYBK 1QKLA 4OIQE 3I4NE 5C44F 3HKZH 2BE5E 4XSZE 3GTOE 4A3BE 3HOYE 2R7ZF 3PO3F 1TWAF 5C3EF 3GTLF 4A3FF 2O5JE 4YG2E 4G7ZE 2Y0SH 5D4CE 3FKIE 4QIWH 5C44E 4KN4E 4BBRF 4YFNE 3S1NF 4Y52F 5C4XF 4OIOE 2R7ZE 1TWAE 4KN7E 3PO3E 3GTKE 4BBSF 5C3EE 3GTLE 4A3FE 5IP7F 5FLMF 4A3CF 4ZH4E 2A6HE 5M3MF 5E18E 5IYDF 2A6EE 4BY7F 4BBRE 5M3FF 2WB1H 3S1NE 4Y52E
chains in the Genus database with same CATH topology
5FJ8F 2O5IE 4Q5SE 4A3DF 1I50F 3HOZF 4JK1E 1I3QF 3GTMF 3S1QF 4YFKE 3S17F 1TWHF 4XLPE 1Y1WF 3S16F 1YNNK 4C3HF 2CW0E 4A3JF 2YU9F 1IW7E 2PPBE 4LJZE 4C3JF 2JA8F 1I6HF 4X6AF 2R92F 3WODE 3EQLE 4MEXE 3M4OF 4A3IF 3K7AF 1I6VE 1TWGF 2NVQF 3H0GF 2E2HF 5IPLE 4LLGE 3HOVF 4OIRE 2NVYF 3HKZK 3RZOF 4KMUE 1K83F 5M5XF 4C2MF 3HOXF 1SMYE 2PMZK 4Q4ZE 3S14F 4Y7NF 3S1MF 2JA6F 3H3VG 4QIWK 5IP9F 4BXXF 3S1RF 1HQME 4C3IF 1R9TF 3GTJF 4MQ9E 4A3EF 2A68E 2R93F 3GTPF 2KRXA 4A3KF 3PO2F 5TMFE 5M5YF 2JA5F 4GZYE 2Y0SI 2VUMF 2WAQK 3S2DF 5BYHE 5C4JF 1ZYRE 2E2IF 4A3LF 1WCMF 4BY1F 3RZDF 3GTKF 5M5WF 2NVXF 3M3YF 3S2HF 3GTGF 3HOWF 5TMCE 5IYBF 4LK1E 3CQZF 4OINE 1SFOF 2B63F 4A3GF 1TWCF 2E2JF 3HOUF 3S15F 2A69E 2WB1I 4A3MF 4A93F 2JA7F 3GTQF 4MEYE 1Y1VF 4YFXE 5IYCF 1TWFF 4OIPE 5E17E 5D4EE 4XLNE 3I4MF 4G7HE 1YNJK 3I4NF 2NVTF 3DXJE 3GTOF 4A3BF 4G7OE 3HOYF 4XSXE 5D4DE 3FKIF 4LK0E 4AYBK 1QKLA 4OIQE 5C44F 2BE5E 4XSZE 2R7ZF 3PO3F 1TWAF 5C3EF 3GTLF 4A3FF 2O5JE 4YG2E 4G7ZE 5D4CE 4KN4E 4BBRF 4YFNE 3S1NF 4Y52F 5C4XF 4OIOE 4KN7E 4BBSF 5IP7F 5FLMF 4A3CF 4ZH4E 2A6HE 5M3MF 5E18E 5IYDF 2A6EE 4BY7F 5M3FF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FJ8 F;  2O5I E;  4Q5S E;  4A3D F;  1I50 F;  3HOZ F;  4JK1 E;  1I3Q F;  3GTM F;  3S1Q F;  4YFK E;  3S17 F;  1TWH F;  4XLP E;  1Y1W F;  3S16 F;  1YNN K;  4C3H F;  2CW0 E;  4A3J F;  2YU9 F;  1IW7 E;  2PPB E;  4LJZ E;  4C3J F;  2JA8 F;  1I6H F;  4X6A F;  2R92 F;  3WOD E;  3EQL E;  4MEX E;  3M4O F;  4A3I F;  3K7A F;  1I6V E;  1TWG F;  2NVQ F;  3H0G F;  2E2H F;  5IPL E;  4LLG E;  3HOV F;  4OIR E;  2NVY F;  3HKZ K;  3RZO F;  4KMU E;  1K83 F;  5M5X F;  4C2M F;  3HOX F;  1SMY E;  2PMZ K;  4Q4Z E;  3S14 F;  4Y7N F;  3S1M F;  2JA6 F;  3H3V G;  5IP9 F;  4BXX F;  3S1R F;  1HQM E;  4C3I F;  1R9T F;  3GTJ F;  4MQ9 E;  4A3E F;  2A68 E;  2R93 F;  3GTP F;  4A3K F;  3PO2 F;  5TMF E;  5M5Y F;  2JA5 F;  4GZY E;  2Y0S I;  2VUM F;  2WAQ K;  3S2D F;  5BYH E;  5C4J F;  1ZYR E;  2E2I F;  4A3L F;  1WCM F;  4BY1 F;  3RZD F;  3GTK F;  5M5W F;  2NVX F;  3M3Y F;  3S2H F;  3GTG F;  3HOW F;  5TMC E;  5IYB F;  4LK1 E;  3CQZ F;  4OIN E;  1SFO F;  2B63 F;  4A3G F;  1TWC F;  2E2J F;  3HOU F;  3S15 F;  2A69 E;  2WB1 I;  4A3M F;  4A93 F;  2JA7 F;  3GTQ F;  4MEY E;  1Y1V F;  4YFX E;  5IYC F;  1TWF F;  4OIP E;  5E17 E;  5D4E E;  4XLN E;  3I4M F;  4G7H E;  1YNJ K;  3I4N F;  2NVT F;  3DXJ E;  3GTO F;  4A3B F;  4G7O E;  3HOY F;  4XSX E;  5D4D E;  3FKI F;  4LK0 E;  4AYB K;  1QKL A;  4OIQ E;  5C44 F;  2BE5 E;  4XSZ E;  2R7Z F;  3PO3 F;  1TWA F;  5C3E F;  3GTL F;  4A3F F;  2O5J E;  4YG2 E;  4G7Z E;  5D4C E;  4KN4 E;  4BBR F;  4YFN E;  3S1N F;  4Y52 F;  5C4X F;  4OIO E;  4KN7 E;  4BBS F;  5IP7 F;  5FLM F;  4A3C F;  4ZH4 E;  2A6H E;  5M3M F;  5E18 E;  5IYD F;  2A6E E;  4BY7 F;  5M3F F; 
#chains in the Genus database with same CATH topology
 4BBS E;  5FJ8 F;  2O5I E;  4Q5S E;  5IP7 E;  5FLM E;  4A3D F;  1I50 F;  4A3C E;  3HOZ F;  4JK1 E;  1I3Q F;  3GTM F;  5IYD E;  5M3M E;  4YFK E;  3H3V F;  3S2H F;  3S17 F;  3S1Q F;  4BY7 E;  5M3F E;  1TWH F;  4XLP E;  1Y1W F;  2PMZ H;  3S16 F;  5FJ8 E;  1YNN K;  1K83 E;  4A3D E;  4C3H F;  1I50 E;  3HOZ E;  2CW0 E;  4A3J F;  1I3Q E;  2YU9 F;  3GTM E;  1IW7 E;  2PPB E;  4LJZ E;  4C3J F;  2JA8 F;  1I6H F;  3S17 E;  2R92 F;  3WOD E;  3S1Q E;  1TWH E;  3EQL E;  4MEX E;  3M4O F;  3M3Y E;  5IP9 E;  3K7A F;  1I6V E;  4A3I F;  1TWG F;  1Y1W E;  2WAQ H;  3H0G F;  2NVQ F;  2E2H F;  3S16 E;  3GTJ E;  5IPL E;  4LLG E;  3HOV F;  4C3H E;  4OIR E;  4A3K E;  2NVY F;  3HKZ K;  4A3J E;  2YU9 E;  4X6A F;  2JA8 E;  4KMU E;  3RZO F;  4C3J E;  2VUM E;  1I6H E;  4X6A E;  2R92 E;  3M4O E;  1K83 F;  1EIK A;  4A3I E;  3K7A E;  1TWG E;  5M5X F;  4C2M F;  2NVQ E;  3H0G E;  2E2H E;  3HOX F;  1SMY E;  2PMZ K;  4Q4Z E;  3S14 F;  3HOV E;  4Y7N F;  3S1M F;  2JA6 F;  3H3V G;  4QIW K;  2NVY E;  5IP9 F;  4BXX F;  3S1R F;  3RZO E;  1HQM E;  4C3I F;  1R9T F;  3GTJ F;  4A3G E;  4MQ9 E;  4A3E F;  2A68 E;  1DZF A;  2R93 F;  3GTP F;  2KRX A;  4A3K F;  5M5X E;  5TMF E;  4C2M E;  5M5Y F;  3PO2 F;  3HOX E;  3S14 E;  2JA5 F;  4GZY E;  2Y0S I;  2VUM F;  2WAQ K;  3S2D F;  5BYH E;  4Y7N E;  3S1M E;  5C4J F;  1ZYR E;  2JA6 E;  4BXX E;  2E2I F;  3S1R E;  4A3L F;  5C4X E;  1WCM F;  4BY1 F;  4C3I E;  3RZD F;  5M5W F;  1R9T E;  2NVX F;  4A3E E;  2NVT E;  3GTK F;  3GTG F;  3HOW F;  3M3Y F;  5TMC E;  3GTP E;  2R93 E;  3PO2 E;  5IYB F;  4LK1 E;  5M5Y E;  3CQZ F;  4AYB H;  1SFO F;  4OIN E;  2JA5 E;  2B63 F;  3S2D E;  4A3G F;  1TWC F;  2E2J F;  5C4J E;  3HOU F;  2A69 E;  3S15 F;  2E2I E;  4A3L E;  2WB1 I;  4A3M F;  4A93 F;  2JA7 F;  3GTQ F;  1WCM E;  4BY1 E;  4MEY E;  1Y1V F;  4YFX E;  5M5W E;  5IYC F;  1TWF F;  4OIP E;  3RZD E;  5D4E E;  2NVX E;  3GTG E;  3HOW E;  3S2H E;  5E17 E;  5IYB E;  3CQZ E;  4XLN E;  1SFO E;  3I4M F;  2B63 E;  4G7H E;  1YNJ K;  1TWC E;  3I4N F;  2NVT F;  2E2J E;  3HOU E;  3S15 E;  3DXJ E;  4A3M E;  3GTO F;  4A93 E;  2JA7 E;  3GTQ E;  4A3B F;  4G7O E;  3HOY F;  4XSX E;  1Y1V E;  5IYC E;  1TWF E;  5D4D E;  3I4M E;  3FKI F;  4LK0 E;  4AYB K;  1QKL A;  4OIQ E;  3I4N E;  5C44 F;  3HKZ H;  2BE5 E;  4XSZ E;  3GTO E;  4A3B E;  3HOY E;  2R7Z F;  3PO3 F;  1TWA F;  5C3E F;  3GTL F;  4A3F F;  2O5J E;  4YG2 E;  4G7Z E;  2Y0S H;  5D4C E;  3FKI E;  4QIW H;  5C44 E;  4KN4 E;  4BBR F;  4YFN E;  3S1N F;  4Y52 F;  5C4X F;  4OIO E;  2R7Z E;  1TWA E;  4KN7 E;  3PO3 E;  3GTK E;  4BBS F;  5C3E E;  3GTL E;  4A3F E;  5IP7 F;  5FLM F;  4A3C F;  4ZH4 E;  2A6H E;  5M3M F;  5E18 E;  5IYD F;  2A6E E;  4BY7 F;  4BBR E;  5M3F F;  2WB1 H;  3S1N E;  4Y52 E; 
#chains in the Genus database with same CATH homology
 5FJ8 F;  2O5I E;  4Q5S E;  4A3D F;  1I50 F;  3HOZ F;  4JK1 E;  1I3Q F;  3GTM F;  3S1Q F;  4YFK E;  3S17 F;  1TWH F;  4XLP E;  1Y1W F;  3S16 F;  1YNN K;  4C3H F;  2CW0 E;  4A3J F;  2YU9 F;  1IW7 E;  2PPB E;  4LJZ E;  4C3J F;  2JA8 F;  1I6H F;  4X6A F;  2R92 F;  3WOD E;  3EQL E;  4MEX E;  3M4O F;  4A3I F;  3K7A F;  1I6V E;  1TWG F;  2NVQ F;  3H0G F;  2E2H F;  5IPL E;  4LLG E;  3HOV F;  4OIR E;  2NVY F;  3HKZ K;  3RZO F;  4KMU E;  1K83 F;  5M5X F;  4C2M F;  3HOX F;  1SMY E;  2PMZ K;  4Q4Z E;  3S14 F;  4Y7N F;  3S1M F;  2JA6 F;  3H3V G;  4QIW K;  5IP9 F;  4BXX F;  3S1R F;  1HQM E;  4C3I F;  1R9T F;  3GTJ F;  4MQ9 E;  4A3E F;  2A68 E;  2R93 F;  3GTP F;  2KRX A;  4A3K F;  3PO2 F;  5TMF E;  5M5Y F;  2JA5 F;  4GZY E;  2Y0S I;  2VUM F;  2WAQ K;  3S2D F;  5BYH E;  5C4J F;  1ZYR E;  2E2I F;  4A3L F;  1WCM F;  4BY1 F;  3RZD F;  3GTK F;  5M5W F;  2NVX F;  3M3Y F;  3S2H F;  3GTG F;  3HOW F;  5TMC E;  5IYB F;  4LK1 E;  3CQZ F;  4OIN E;  1SFO F;  2B63 F;  4A3G F;  1TWC F;  2E2J F;  3HOU F;  3S15 F;  2A69 E;  2WB1 I;  4A3M F;  4A93 F;  2JA7 F;  3GTQ F;  4MEY E;  1Y1V F;  4YFX E;  5IYC F;  1TWF F;  4OIP E;  5E17 E;  5D4E E;  4XLN E;  3I4M F;  4G7H E;  1YNJ K;  3I4N F;  2NVT F;  3DXJ E;  3GTO F;  4A3B F;  4G7O E;  3HOY F;  4XSX E;  5D4D E;  3FKI F;  4LK0 E;  4AYB K;  1QKL A;  4OIQ E;  5C44 F;  2BE5 E;  4XSZ E;  2R7Z F;  3PO3 F;  1TWA F;  5C3E F;  3GTL F;  4A3F F;  2O5J E;  4YG2 E;  4G7Z E;  5D4C E;  4KN4 E;  4BBR F;  4YFN E;  3S1N F;  4Y52 F;  5C4X F;  4OIO E;  4KN7 E;  4BBS F;  5IP7 F;  5FLM F;  4A3C F;  4ZH4 E;  2A6H E;  5M3M F;  5E18 E;  5IYD F;  2A6E E;  4BY7 F;  5M3F F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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