1LD5A

Structure of bpti mutant a16v
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCRVRIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCLRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Bos taurus
molecule keywords PANCREATIC TRYPSIN INHIBITOR
total genus 7
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2002-04-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1ld5A00
3TGJI 3FP6I 1T8LB 1T8NB 3UOUB 1F5RI 2LFKA 3D65I 1UUAA 2M99A 1BTHP 3AUBA 1KUNA 1EJMB 3BTMI 2W8XA 1BHCA 2FI3I 1BF0A 1BZXI 1YLDB 2KAII 3LDJA 5C67C 3BTWI 1T8MB 2ODYE 4ISNB 1YKTB 3AUEA 3M7QB 4DG4C 2CA7A 1SHPA 2M01A 4WXVC 1NAGA 4Y0ZI 3TPII 1ZJDB 4U32X 3AUCA 1BZ5A 2R9PE 1BTIA 3P95E 1TAPA 3BTFI 3L3TE 1JC6A 2IJOI 1Y62A 4BD9B 1BRCI 3TGKI 3L33E 2FI4I 1CO7I 1IRHA 1KNTA 1P2KI 4ISOB 1T8OB 1CBWD 4NTXB 1F7ZI 1D0DA 1TCPA 3UIRC 2ZJXA 5PTIA 1PITA 1P2JI 2KNTA 1P2II 4ISLB 1ADZA 2ZVXA 3LDIA 2FI5I 1K6UA 1EAWB 3BTKI 5JB6A 3GYMI 1UUBA 2DDIA 3BTDI 4Y11I 1BPTA 1AAPA 4NTYB 9PTIA 1KTHA 1OA65 2J6DA 3AUIA 1TOCR 4WWYC 3P92E 1G6XA 1BIKA 2FTLI 1DENA 1DEMA 1FAKI 2UUXA 7PTIA 1D0DB 3AUGA 4Y0YI 1YLCB 1FANA 3OFWA 3FP8I 1YC0I 1FY8I 2FTMB 1CA0D 3BTGI 1DTXA 1P2OB 1TFXC 8PTIA 4TPII 1P2NB 5JB7A 3AUHA 1LD6A 4BQDA 1DTKA 3CI7A 2RA3C 3FP7J 5JB4A 3OTJI 4PTIA 2KCRA 2TPII 3BTEI 1QLQA 1LD5A 4BNRI 3AUDA 1AALA 2JOTA 2LFLA 2PTCI 1TAWB 1BRBI 2UUYB 3BTTI 3BTQI 3BTHI 1P2MB 1JV9A 3TGII 3U1JE 2DDJA 1T7CB 3LDMA 6PTIA 4U30W 3T62D 2HEXA 1JV8A 4Y10I 1BPIA 1P2QB 1OA55 1ZR0B 4DTGK 1KIGI 1BUNB 3BYBA 4NTWB 5JB5A 3WNYA 1B0CA 1MTND 1TPAI 2TGPI
chains in the Genus database with same CATH superfamily
3TGJI 3FP6I 1T8LB 1T8NB 3UOUB 1F5RI 2LFKA 3D65I 1UUAA 2M99A 1BTHP 3AUBA 1KUNA 1EJMB 3BTMI 2W8XA 1BHCA 2FI3I 1BF0A 1BZXI 1YLDB 2KAII 3LDJA 5C67C 3BTWI 1T8MB 2ODYE 4ISNB 1YKTB 3AUEA 3M7QB 4DG4C 2CA7A 1SHPA 2M01A 4WXVC 1NAGA 4Y0ZI 3TPII 1ZJDB 4U32X 3AUCA 1BZ5A 2R9PE 1BTIA 3P95E 1TAPA 3BTFI 3L3TE 1JC6A 2IJOI 1Y62A 4BD9B 1BRCI 3TGKI 3L33E 2FI4I 1CO7I 1IRHA 1KNTA 1P2KI 4ISOB 1T8OB 1CBWD 4NTXB 1F7ZI 1D0DA 1TCPA 3UIRC 2ZJXA 5PTIA 1PITA 1P2JI 2KNTA 1P2II 4ISLB 1ADZA 2ZVXA 3LDIA 2FI5I 1K6UA 1EAWB 3BTKI 5JB6A 3GYMI 1UUBA 2DDIA 3BTDI 4Y11I 1BPTA 1AAPA 4NTYB 9PTIA 1KTHA 1OA65 2J6DA 3AUIA 1TOCR 4WWYC 3P92E 1G6XA 1BIKA 2FTLI 1DENA 1DEMA 1FAKI 2UUXA 7PTIA 1D0DB 3AUGA 4Y0YI 1YLCB 1FANA 3OFWA 3FP8I 1YC0I 1FY8I 2FTMB 1CA0D 3BTGI 1DTXA 1P2OB 1TFXC 8PTIA 4TPII 1P2NB 5JB7A 3AUHA 1LD6A 4BQDA 1DTKA 3CI7A 2RA3C 3FP7J 5JB4A 3OTJI 4PTIA 2KCRA 2TPII 3BTEI 1QLQA 1LD5A 4BNRI 3AUDA 1AALA 2JOTA 2LFLA 2PTCI 1TAWB 1BRBI 2UUYB 3BTTI 3BTQI 3BTHI 1P2MB 1JV9A 3TGII 3U1JE 2DDJA 1T7CB 3LDMA 6PTIA 4U30W 3T62D 2HEXA 1JV8A 4Y10I 1BPIA 1P2QB 1OA55 1ZR0B 4DTGK 1KIGI 1BUNB 3BYBA 4NTWB 5JB5A 3WNYA 1B0CA 1MTND 1TPAI 2TGPI
chains in the Genus database with same CATH topology
3TGJI 3FP6I 1T8LB 1T8NB 3UOUB 1F5RI 2LFKA 3D65I 1UUAA 2M99A 1BTHP 3AUBA 1KUNA 1EJMB 3BTMI 2W8XA 1BHCA 2FI3I 1BF0A 1BZXI 1YLDB 2KAII 3LDJA 5C67C 3BTWI 1T8MB 2ODYE 4ISNB 1YKTB 3AUEA 3M7QB 4DG4C 2CA7A 1SHPA 2M01A 4WXVC 1NAGA 4Y0ZI 3TPII 1ZJDB 4U32X 3AUCA 1BZ5A 2R9PE 1BTIA 3P95E 1TAPA 3BTFI 3L3TE 1JC6A 2IJOI 1Y62A 4BD9B 1BRCI 3TGKI 3L33E 2FI4I 1CO7I 1IRHA 1KNTA 1P2KI 4ISOB 1T8OB 1CBWD 4NTXB 1F7ZI 1D0DA 1TCPA 3UIRC 2ZJXA 5PTIA 1PITA 1P2JI 2KNTA 1P2II 4ISLB 1ADZA 2ZVXA 3LDIA 2FI5I 1K6UA 1EAWB 3BTKI 5JB6A 3GYMI 1UUBA 2DDIA 3BTDI 4Y11I 1BPTA 1AAPA 4NTYB 9PTIA 1KTHA 1OA65 2J6DA 3AUIA 1TOCR 4WWYC 3P92E 1G6XA 1BIKA 2FTLI 1DENA 1DEMA 1FAKI 2UUXA 7PTIA 1D0DB 3AUGA 4Y0YI 1YLCB 1FANA 3OFWA 3FP8I 1YC0I 1FY8I 2FTMB 1CA0D 3BTGI 1DTXA 1P2OB 1TFXC 8PTIA 4TPII 1P2NB 5JB7A 3AUHA 1LD6A 4BQDA 1DTKA 3CI7A 2RA3C 3FP7J 5JB4A 3OTJI 4PTIA 2KCRA 2TPII 3BTEI 1QLQA 1LD5A 4BNRI 3AUDA 1AALA 2JOTA 2LFLA 2PTCI 1TAWB 1BRBI 2UUYB 3BTTI 3BTQI 3BTHI 1P2MB 1JV9A 3TGII 3U1JE 2DDJA 1T7CB 3LDMA 6PTIA 4U30W 3T62D 2HEXA 1JV8A 4Y10I 1BPIA 1P2QB 1OA55 1ZR0B 4DTGK 1KIGI 1BUNB 3BYBA 4NTWB 5JB5A 3WNYA 1B0CA 1MTND 1TPAI 2TGPI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TGJ I;  3FP6 I;  1T8L B;  1T8N B;  3UOU B;  1F5R I;  2LFK A;  3D65 I;  1UUA A;  2M99 A;  1BTH P;  3AUB A;  1KUN A;  1EJM B;  3BTM I;  2W8X A;  1BHC A;  2FI3 I;  1BF0 A;  1BZX I;  1YLD B;  2KAI I;  3LDJ A;  5C67 C;  3BTW I;  1T8M B;  2ODY E;  4ISN B;  1YKT B;  3AUE A;  3M7Q B;  4DG4 C;  2CA7 A;  1SHP A;  2M01 A;  4WXV C;  1NAG A;  4Y0Z I;  3TPI I;  1ZJD B;  4U32 X;  3AUC A;  1BZ5 A;  2R9P E;  1BTI A;  3P95 E;  1TAP A;  3BTF I;  3L3T E;  1JC6 A;  2IJO I;  1Y62 A;  4BD9 B;  1BRC I;  3TGK I;  3L33 E;  2FI4 I;  1CO7 I;  1IRH A;  1KNT A;  1P2K I;  4ISO B;  1T8O B;  1CBW D;  4NTX B;  1F7Z I;  1D0D A;  1TCP A;  3UIR C;  2ZJX A;  5PTI A;  1PIT A;  1P2J I;  2KNT A;  1P2I I;  4ISL B;  1ADZ A;  2ZVX A;  3LDI A;  2FI5 I;  1K6U A;  1EAW B;  3BTK I;  5JB6 A;  3GYM I;  1UUB A;  2DDI A;  3BTD I;  4Y11 I;  1BPT A;  1AAP A;  4NTY B;  9PTI A;  1KTH A;  1OA6 5;  2J6D A;  3AUI A;  1TOC R;  4WWY C;  3P92 E;  1G6X A;  1BIK A;  2FTL I;  1DEN A;  1DEM A;  1FAK I;  2UUX A;  7PTI A;  1D0D B;  3AUG A;  4Y0Y I;  1YLC B;  1FAN A;  3OFW A;  3FP8 I;  1YC0 I;  1FY8 I;  2FTM B;  1CA0 D;  3BTG I;  1DTX A;  1P2O B;  1TFX C;  8PTI A;  4TPI I;  1P2N B;  5JB7 A;  3AUH A;  1LD6 A;  4BQD A;  1DTK A;  3CI7 A;  2RA3 C;  3FP7 J;  5JB4 A;  3OTJ I;  4PTI A;  2KCR A;  2TPI I;  3BTE I;  1QLQ A;  1LD5 A;  4BNR I;  3AUD A;  1AAL A;  2JOT A;  2LFL A;  2PTC I;  1TAW B;  1BRB I;  2UUY B;  3BTT I;  3BTQ I;  3BTH I;  1P2M B;  1JV9 A;  3TGI I;  3U1J E;  2DDJ A;  1T7C B;  3LDM A;  6PTI A;  4U30 W;  3T62 D;  2HEX A;  1JV8 A;  4Y10 I;  1BPI A;  1P2Q B;  1OA5 5;  1ZR0 B;  4DTG K;  1KIG I;  1BUN B;  3BYB A;  4NTW B;  5JB5 A;  3WNY A;  1B0C A;  1MTN D;  1TPA I;  2TGP I; 
#chains in the Genus database with same CATH topology
 3TGJ I;  3FP6 I;  1T8L B;  1T8N B;  3UOU B;  1F5R I;  2LFK A;  3D65 I;  1UUA A;  2M99 A;  1BTH P;  3AUB A;  1KUN A;  1EJM B;  3BTM I;  2W8X A;  1BHC A;  2FI3 I;  1BF0 A;  1BZX I;  1YLD B;  2KAI I;  3LDJ A;  5C67 C;  3BTW I;  1T8M B;  2ODY E;  4ISN B;  1YKT B;  3AUE A;  3M7Q B;  4DG4 C;  2CA7 A;  1SHP A;  2M01 A;  4WXV C;  1NAG A;  4Y0Z I;  3TPI I;  1ZJD B;  4U32 X;  3AUC A;  1BZ5 A;  2R9P E;  1BTI A;  3P95 E;  1TAP A;  3BTF I;  3L3T E;  1JC6 A;  2IJO I;  1Y62 A;  4BD9 B;  1BRC I;  3TGK I;  3L33 E;  2FI4 I;  1CO7 I;  1IRH A;  1KNT A;  1P2K I;  4ISO B;  1T8O B;  1CBW D;  4NTX B;  1F7Z I;  1D0D A;  1TCP A;  3UIR C;  2ZJX A;  5PTI A;  1PIT A;  1P2J I;  2KNT A;  1P2I I;  4ISL B;  1ADZ A;  2ZVX A;  3LDI A;  2FI5 I;  1K6U A;  1EAW B;  3BTK I;  5JB6 A;  3GYM I;  1UUB A;  2DDI A;  3BTD I;  4Y11 I;  1BPT A;  1AAP A;  4NTY B;  9PTI A;  1KTH A;  1OA6 5;  2J6D A;  3AUI A;  1TOC R;  4WWY C;  3P92 E;  1G6X A;  1BIK A;  2FTL I;  1DEN A;  1DEM A;  1FAK I;  2UUX A;  7PTI A;  1D0D B;  3AUG A;  4Y0Y I;  1YLC B;  1FAN A;  3OFW A;  3FP8 I;  1YC0 I;  1FY8 I;  2FTM B;  1CA0 D;  3BTG I;  1DTX A;  1P2O B;  1TFX C;  8PTI A;  4TPI I;  1P2N B;  5JB7 A;  3AUH A;  1LD6 A;  4BQD A;  1DTK A;  3CI7 A;  2RA3 C;  3FP7 J;  5JB4 A;  3OTJ I;  4PTI A;  2KCR A;  2TPI I;  3BTE I;  1QLQ A;  1LD5 A;  4BNR I;  3AUD A;  1AAL A;  2JOT A;  2LFL A;  2PTC I;  1TAW B;  1BRB I;  2UUY B;  3BTT I;  3BTQ I;  3BTH I;  1P2M B;  1JV9 A;  3TGI I;  3U1J E;  2DDJ A;  1T7C B;  3LDM A;  6PTI A;  4U30 W;  3T62 D;  2HEX A;  1JV8 A;  4Y10 I;  1BPI A;  1P2Q B;  1OA5 5;  1ZR0 B;  4DTG K;  1KIG I;  1BUN B;  3BYB A;  4NTW B;  5JB5 A;  3WNY A;  1B0C A;  1MTN D;  1TPA I;  2TGP I; 
#chains in the Genus database with same CATH homology
 3TGJ I;  3FP6 I;  1T8L B;  1T8N B;  3UOU B;  1F5R I;  2LFK A;  3D65 I;  1UUA A;  2M99 A;  1BTH P;  3AUB A;  1KUN A;  1EJM B;  3BTM I;  2W8X A;  1BHC A;  2FI3 I;  1BF0 A;  1BZX I;  1YLD B;  2KAI I;  3LDJ A;  5C67 C;  3BTW I;  1T8M B;  2ODY E;  4ISN B;  1YKT B;  3AUE A;  3M7Q B;  4DG4 C;  2CA7 A;  1SHP A;  2M01 A;  4WXV C;  1NAG A;  4Y0Z I;  3TPI I;  1ZJD B;  4U32 X;  3AUC A;  1BZ5 A;  2R9P E;  1BTI A;  3P95 E;  1TAP A;  3BTF I;  3L3T E;  1JC6 A;  2IJO I;  1Y62 A;  4BD9 B;  1BRC I;  3TGK I;  3L33 E;  2FI4 I;  1CO7 I;  1IRH A;  1KNT A;  1P2K I;  4ISO B;  1T8O B;  1CBW D;  4NTX B;  1F7Z I;  1D0D A;  1TCP A;  3UIR C;  2ZJX A;  5PTI A;  1PIT A;  1P2J I;  2KNT A;  1P2I I;  4ISL B;  1ADZ A;  2ZVX A;  3LDI A;  2FI5 I;  1K6U A;  1EAW B;  3BTK I;  5JB6 A;  3GYM I;  1UUB A;  2DDI A;  3BTD I;  4Y11 I;  1BPT A;  1AAP A;  4NTY B;  9PTI A;  1KTH A;  1OA6 5;  2J6D A;  3AUI A;  1TOC R;  4WWY C;  3P92 E;  1G6X A;  1BIK A;  2FTL I;  1DEN A;  1DEM A;  1FAK I;  2UUX A;  7PTI A;  1D0D B;  3AUG A;  4Y0Y I;  1YLC B;  1FAN A;  3OFW A;  3FP8 I;  1YC0 I;  1FY8 I;  2FTM B;  1CA0 D;  3BTG I;  1DTX A;  1P2O B;  1TFX C;  8PTI A;  4TPI I;  1P2N B;  5JB7 A;  3AUH A;  1LD6 A;  4BQD A;  1DTK A;  3CI7 A;  2RA3 C;  3FP7 J;  5JB4 A;  3OTJ I;  4PTI A;  2KCR A;  2TPI I;  3BTE I;  1QLQ A;  1LD5 A;  4BNR I;  3AUD A;  1AAL A;  2JOT A;  2LFL A;  2PTC I;  1TAW B;  1BRB I;  2UUY B;  3BTT I;  3BTQ I;  3BTH I;  1P2M B;  1JV9 A;  3TGI I;  3U1J E;  2DDJ A;  1T7C B;  3LDM A;  6PTI A;  4U30 W;  3T62 D;  2HEX A;  1JV8 A;  4Y10 I;  1BPI A;  1P2Q B;  1OA5 5;  1ZR0 B;  4DTG K;  1KIG I;  1BUN B;  3BYB A;  4NTW B;  5JB5 A;  3WNY A;  1B0C A;  1MTN D;  1TPA I;  2TGP I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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