1LD6A

Structure of bpti_8a mutant
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYAGACRAAAARYFYNAKAGLCQTFAYGACAAKRNNFKSAEDCLRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Bos taurus
molecule keywords PANCREATIC TRYPSIN INHIBITOR
total genus 5
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2002-04-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1ld6A00
3FP6I 4U30W 3FP7J 1BIKA 1T8NB 3LDMA 2ODYE 1UUBA 1CO7I 4WWYC 1PITA 2KAII 1AAPA 1BRBI 3TGKI 4NTWB 5PTIA 3FP8I 3BTDI 3TGII 2UUYB 1BUNB 3D65I 3UOUB 1JV8A 3AUIA 1TPAI 1D0DB 1Y62A 4DG4C 3LDIA 1BPTA 4PTIA 2LFKA 1CBWD 2ZVXA 3BYBA 3TPII 3L3TE 2FI5I 4WXVC 3BTKI 1D0DA 4DTGK 1YLCB 2RA3C 1UUAA 4Y0YI 1SHPA 1OA55 5C67C 2JOTA 3M7QB 4NTXB 2TGPI 1BTHP 1KNTA 1P2KI 2DDIA 4BQDA 1T7CB 2TPII 1ZJDB 3BTHI 1DTKA 1LD5A 1CA0D 1LD6A 1BPIA 4BD9B 3BTMI 1TCPA 3BTTI 1KTHA 1EJMB 1B0CA 3BTFI 3AUGA 6PTIA 4Y10I 3AUHA 1FAKI 1TOCR 3AUBA 2DDJA 3OTJI 1T8OB 2FI3I 1F5RI 1BRCI 9PTIA 1YC0I 2J6DA 3UIRC 4Y11I 2FTLI 3L33E 1FANA 5JB4A 1DEMA 1MTND 1QLQA 4BNRI 4ISOB 8PTIA 5JB5A 1BZ5A 4U32X 2CA7A 1JV9A 3TGJI 1ZR0B 1TFXC 2M01A 3AUCA 3T62D 4TPII 1T8LB 1BZXI 1F7ZI 3OFWA 1G6XA 3AUDA 2IJOI 2HEXA 3P95E 2M99A 2FTMB 1P2II 1YLDB 1ADZA 2FI4I 1EAWB 2W8XA 1DENA 3BTQI 3GYMI 4NTYB 3AUEA 1YKTB 1P2OB 3BTEI 3WNYA 3BTWI 2R9PE 7PTIA 2LFLA 1P2MB 1KIGI 2ZJXA 1NAGA 1BHCA 2PTCI 4Y0ZI 2KCRA 2UUXA 1KUNA 1AALA 3LDJA 5JB7A 1BF0A 4ISLB 1BTIA 1P2QB 3BTGI 4ISNB 3CI7A 1FY8I 1TAPA 1TAWB 1K6UA 1JC6A 2KNTA 1OA65 1DTXA 3P92E 1P2NB 1IRHA 1P2JI 3U1JE 5JB6A 1T8MB
chains in the Genus database with same CATH superfamily
3FP6I 4U30W 3FP7J 1BIKA 1T8NB 3LDMA 2ODYE 1UUBA 1CO7I 4WWYC 1PITA 2KAII 1AAPA 1BRBI 3TGKI 4NTWB 5PTIA 3FP8I 3BTDI 3TGII 2UUYB 1BUNB 3D65I 3UOUB 1JV8A 3AUIA 1TPAI 1D0DB 1Y62A 4DG4C 3LDIA 1BPTA 4PTIA 2LFKA 1CBWD 2ZVXA 3BYBA 3TPII 3L3TE 2FI5I 4WXVC 3BTKI 1D0DA 4DTGK 1YLCB 2RA3C 1UUAA 4Y0YI 1SHPA 1OA55 5C67C 2JOTA 3M7QB 4NTXB 2TGPI 1BTHP 1KNTA 1P2KI 2DDIA 4BQDA 1T7CB 2TPII 1ZJDB 3BTHI 1DTKA 1LD5A 1CA0D 1LD6A 1BPIA 4BD9B 3BTMI 1TCPA 3BTTI 1KTHA 1EJMB 1B0CA 3BTFI 3AUGA 6PTIA 4Y10I 3AUHA 1FAKI 1TOCR 3AUBA 2DDJA 3OTJI 1T8OB 2FI3I 1F5RI 1BRCI 9PTIA 1YC0I 2J6DA 3UIRC 4Y11I 2FTLI 3L33E 1FANA 5JB4A 1DEMA 1MTND 1QLQA 4BNRI 4ISOB 8PTIA 5JB5A 1BZ5A 4U32X 2CA7A 1JV9A 3TGJI 1ZR0B 1TFXC 2M01A 3AUCA 3T62D 4TPII 1T8LB 1BZXI 1F7ZI 3OFWA 1G6XA 3AUDA 2IJOI 2HEXA 3P95E 2M99A 2FTMB 1P2II 1YLDB 1ADZA 2FI4I 1EAWB 2W8XA 1DENA 3BTQI 3GYMI 4NTYB 3AUEA 1YKTB 1P2OB 3BTEI 3WNYA 3BTWI 2R9PE 7PTIA 2LFLA 1P2MB 1KIGI 2ZJXA 1NAGA 1BHCA 2PTCI 4Y0ZI 2KCRA 2UUXA 1KUNA 1AALA 3LDJA 5JB7A 1BF0A 4ISLB 1BTIA 1P2QB 3BTGI 4ISNB 3CI7A 1FY8I 1TAPA 1TAWB 1K6UA 1JC6A 2KNTA 1OA65 1DTXA 3P92E 1P2NB 1IRHA 1P2JI 3U1JE 5JB6A 1T8MB
chains in the Genus database with same CATH topology
3FP6I 4U30W 3FP7J 1BIKA 1T8NB 3LDMA 2ODYE 1UUBA 1CO7I 4WWYC 1PITA 2KAII 1AAPA 1BRBI 3TGKI 4NTWB 5PTIA 3FP8I 3BTDI 3TGII 2UUYB 1BUNB 3D65I 3UOUB 1JV8A 3AUIA 1TPAI 1D0DB 1Y62A 4DG4C 3LDIA 1BPTA 4PTIA 2LFKA 1CBWD 2ZVXA 3BYBA 3TPII 3L3TE 2FI5I 4WXVC 3BTKI 1D0DA 4DTGK 1YLCB 2RA3C 1UUAA 4Y0YI 1SHPA 1OA55 5C67C 2JOTA 3M7QB 4NTXB 2TGPI 1BTHP 1KNTA 1P2KI 2DDIA 4BQDA 1T7CB 2TPII 1ZJDB 3BTHI 1DTKA 1LD5A 1CA0D 1LD6A 1BPIA 4BD9B 3BTMI 1TCPA 3BTTI 1KTHA 1EJMB 1B0CA 3BTFI 3AUGA 6PTIA 4Y10I 3AUHA 1FAKI 1TOCR 3AUBA 2DDJA 3OTJI 1T8OB 2FI3I 1F5RI 1BRCI 9PTIA 1YC0I 2J6DA 3UIRC 4Y11I 2FTLI 3L33E 1FANA 5JB4A 1DEMA 1MTND 1QLQA 4BNRI 4ISOB 8PTIA 5JB5A 1BZ5A 4U32X 2CA7A 1JV9A 3TGJI 1ZR0B 1TFXC 2M01A 3AUCA 3T62D 4TPII 1T8LB 1BZXI 1F7ZI 3OFWA 1G6XA 3AUDA 2IJOI 2HEXA 3P95E 2M99A 2FTMB 1P2II 1YLDB 1ADZA 2FI4I 1EAWB 2W8XA 1DENA 3BTQI 3GYMI 4NTYB 3AUEA 1YKTB 1P2OB 3BTEI 3WNYA 3BTWI 2R9PE 7PTIA 2LFLA 1P2MB 1KIGI 2ZJXA 1NAGA 1BHCA 2PTCI 4Y0ZI 2KCRA 2UUXA 1KUNA 1AALA 3LDJA 5JB7A 1BF0A 4ISLB 1BTIA 1P2QB 3BTGI 4ISNB 3CI7A 1FY8I 1TAPA 1TAWB 1K6UA 1JC6A 2KNTA 1OA65 1DTXA 3P92E 1P2NB 1IRHA 1P2JI 3U1JE 5JB6A 1T8MB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FP6 I;  4U30 W;  3FP7 J;  1BIK A;  1T8N B;  3LDM A;  2ODY E;  1UUB A;  1CO7 I;  4WWY C;  1PIT A;  2KAI I;  1AAP A;  1BRB I;  3TGK I;  4NTW B;  5PTI A;  3FP8 I;  3BTD I;  3TGI I;  2UUY B;  1BUN B;  3D65 I;  3UOU B;  1JV8 A;  3AUI A;  1TPA I;  1D0D B;  1Y62 A;  4DG4 C;  3LDI A;  1BPT A;  4PTI A;  2LFK A;  1CBW D;  2ZVX A;  3BYB A;  3TPI I;  3L3T E;  2FI5 I;  4WXV C;  3BTK I;  1D0D A;  4DTG K;  1YLC B;  2RA3 C;  1UUA A;  4Y0Y I;  1SHP A;  1OA5 5;  5C67 C;  2JOT A;  3M7Q B;  4NTX B;  2TGP I;  1BTH P;  1KNT A;  1P2K I;  2DDI A;  4BQD A;  1T7C B;  2TPI I;  1ZJD B;  3BTH I;  1DTK A;  1LD5 A;  1CA0 D;  1LD6 A;  1BPI A;  4BD9 B;  3BTM I;  1TCP A;  3BTT I;  1KTH A;  1EJM B;  1B0C A;  3BTF I;  3AUG A;  6PTI A;  4Y10 I;  3AUH A;  1FAK I;  1TOC R;  3AUB A;  2DDJ A;  3OTJ I;  1T8O B;  2FI3 I;  1F5R I;  1BRC I;  9PTI A;  1YC0 I;  2J6D A;  3UIR C;  4Y11 I;  2FTL I;  3L33 E;  1FAN A;  5JB4 A;  1DEM A;  1MTN D;  1QLQ A;  4BNR I;  4ISO B;  8PTI A;  5JB5 A;  1BZ5 A;  4U32 X;  2CA7 A;  1JV9 A;  3TGJ I;  1ZR0 B;  1TFX C;  2M01 A;  3AUC A;  3T62 D;  4TPI I;  1T8L B;  1BZX I;  1F7Z I;  3OFW A;  1G6X A;  3AUD A;  2IJO I;  2HEX A;  3P95 E;  2M99 A;  2FTM B;  1P2I I;  1YLD B;  1ADZ A;  2FI4 I;  1EAW B;  2W8X A;  1DEN A;  3BTQ I;  3GYM I;  4NTY B;  3AUE A;  1YKT B;  1P2O B;  3BTE I;  3WNY A;  3BTW I;  2R9P E;  7PTI A;  2LFL A;  1P2M B;  1KIG I;  2ZJX A;  1NAG A;  1BHC A;  2PTC I;  4Y0Z I;  2KCR A;  2UUX A;  1KUN A;  1AAL A;  3LDJ A;  5JB7 A;  1BF0 A;  4ISL B;  1BTI A;  1P2Q B;  3BTG I;  4ISN B;  3CI7 A;  1FY8 I;  1TAP A;  1TAW B;  1K6U A;  1JC6 A;  2KNT A;  1OA6 5;  1DTX A;  3P92 E;  1P2N B;  1IRH A;  1P2J I;  3U1J E;  5JB6 A;  1T8M B; 
#chains in the Genus database with same CATH topology
 3FP6 I;  4U30 W;  3FP7 J;  1BIK A;  1T8N B;  3LDM A;  2ODY E;  1UUB A;  1CO7 I;  4WWY C;  1PIT A;  2KAI I;  1AAP A;  1BRB I;  3TGK I;  4NTW B;  5PTI A;  3FP8 I;  3BTD I;  3TGI I;  2UUY B;  1BUN B;  3D65 I;  3UOU B;  1JV8 A;  3AUI A;  1TPA I;  1D0D B;  1Y62 A;  4DG4 C;  3LDI A;  1BPT A;  4PTI A;  2LFK A;  1CBW D;  2ZVX A;  3BYB A;  3TPI I;  3L3T E;  2FI5 I;  4WXV C;  3BTK I;  1D0D A;  4DTG K;  1YLC B;  2RA3 C;  1UUA A;  4Y0Y I;  1SHP A;  1OA5 5;  5C67 C;  2JOT A;  3M7Q B;  4NTX B;  2TGP I;  1BTH P;  1KNT A;  1P2K I;  2DDI A;  4BQD A;  1T7C B;  2TPI I;  1ZJD B;  3BTH I;  1DTK A;  1LD5 A;  1CA0 D;  1LD6 A;  1BPI A;  4BD9 B;  3BTM I;  1TCP A;  3BTT I;  1KTH A;  1EJM B;  1B0C A;  3BTF I;  3AUG A;  6PTI A;  4Y10 I;  3AUH A;  1FAK I;  1TOC R;  3AUB A;  2DDJ A;  3OTJ I;  1T8O B;  2FI3 I;  1F5R I;  1BRC I;  9PTI A;  1YC0 I;  2J6D A;  3UIR C;  4Y11 I;  2FTL I;  3L33 E;  1FAN A;  5JB4 A;  1DEM A;  1MTN D;  1QLQ A;  4BNR I;  4ISO B;  8PTI A;  5JB5 A;  1BZ5 A;  4U32 X;  2CA7 A;  1JV9 A;  3TGJ I;  1ZR0 B;  1TFX C;  2M01 A;  3AUC A;  3T62 D;  4TPI I;  1T8L B;  1BZX I;  1F7Z I;  3OFW A;  1G6X A;  3AUD A;  2IJO I;  2HEX A;  3P95 E;  2M99 A;  2FTM B;  1P2I I;  1YLD B;  1ADZ A;  2FI4 I;  1EAW B;  2W8X A;  1DEN A;  3BTQ I;  3GYM I;  4NTY B;  3AUE A;  1YKT B;  1P2O B;  3BTE I;  3WNY A;  3BTW I;  2R9P E;  7PTI A;  2LFL A;  1P2M B;  1KIG I;  2ZJX A;  1NAG A;  1BHC A;  2PTC I;  4Y0Z I;  2KCR A;  2UUX A;  1KUN A;  1AAL A;  3LDJ A;  5JB7 A;  1BF0 A;  4ISL B;  1BTI A;  1P2Q B;  3BTG I;  4ISN B;  3CI7 A;  1FY8 I;  1TAP A;  1TAW B;  1K6U A;  1JC6 A;  2KNT A;  1OA6 5;  1DTX A;  3P92 E;  1P2N B;  1IRH A;  1P2J I;  3U1J E;  5JB6 A;  1T8M B; 
#chains in the Genus database with same CATH homology
 3FP6 I;  4U30 W;  3FP7 J;  1BIK A;  1T8N B;  3LDM A;  2ODY E;  1UUB A;  1CO7 I;  4WWY C;  1PIT A;  2KAI I;  1AAP A;  1BRB I;  3TGK I;  4NTW B;  5PTI A;  3FP8 I;  3BTD I;  3TGI I;  2UUY B;  1BUN B;  3D65 I;  3UOU B;  1JV8 A;  3AUI A;  1TPA I;  1D0D B;  1Y62 A;  4DG4 C;  3LDI A;  1BPT A;  4PTI A;  2LFK A;  1CBW D;  2ZVX A;  3BYB A;  3TPI I;  3L3T E;  2FI5 I;  4WXV C;  3BTK I;  1D0D A;  4DTG K;  1YLC B;  2RA3 C;  1UUA A;  4Y0Y I;  1SHP A;  1OA5 5;  5C67 C;  2JOT A;  3M7Q B;  4NTX B;  2TGP I;  1BTH P;  1KNT A;  1P2K I;  2DDI A;  4BQD A;  1T7C B;  2TPI I;  1ZJD B;  3BTH I;  1DTK A;  1LD5 A;  1CA0 D;  1LD6 A;  1BPI A;  4BD9 B;  3BTM I;  1TCP A;  3BTT I;  1KTH A;  1EJM B;  1B0C A;  3BTF I;  3AUG A;  6PTI A;  4Y10 I;  3AUH A;  1FAK I;  1TOC R;  3AUB A;  2DDJ A;  3OTJ I;  1T8O B;  2FI3 I;  1F5R I;  1BRC I;  9PTI A;  1YC0 I;  2J6D A;  3UIR C;  4Y11 I;  2FTL I;  3L33 E;  1FAN A;  5JB4 A;  1DEM A;  1MTN D;  1QLQ A;  4BNR I;  4ISO B;  8PTI A;  5JB5 A;  1BZ5 A;  4U32 X;  2CA7 A;  1JV9 A;  3TGJ I;  1ZR0 B;  1TFX C;  2M01 A;  3AUC A;  3T62 D;  4TPI I;  1T8L B;  1BZX I;  1F7Z I;  3OFW A;  1G6X A;  3AUD A;  2IJO I;  2HEX A;  3P95 E;  2M99 A;  2FTM B;  1P2I I;  1YLD B;  1ADZ A;  2FI4 I;  1EAW B;  2W8X A;  1DEN A;  3BTQ I;  3GYM I;  4NTY B;  3AUE A;  1YKT B;  1P2O B;  3BTE I;  3WNY A;  3BTW I;  2R9P E;  7PTI A;  2LFL A;  1P2M B;  1KIG I;  2ZJX A;  1NAG A;  1BHC A;  2PTC I;  4Y0Z I;  2KCR A;  2UUX A;  1KUN A;  1AAL A;  3LDJ A;  5JB7 A;  1BF0 A;  4ISL B;  1BTI A;  1P2Q B;  3BTG I;  4ISN B;  3CI7 A;  1FY8 I;  1TAP A;  1TAW B;  1K6U A;  1JC6 A;  2KNT A;  1OA6 5;  1DTX A;  3P92 E;  1P2N B;  1IRH A;  1P2J I;  3U1J E;  5JB6 A;  1T8M B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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