1NQGA

Outer membrane cobalamin transporter (btub) from e. coli, with bound calcium
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
589
structure length
576
Chain Sequence
DTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFLSKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDADTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPHDSSATLDEMKQYTVQWANNVIVGHGSIGAGVDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARNAITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Substrate-induced transmembrane signaling in the cobalamin transporter BtuB
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords vitamin b12 receptor
total genus 148
structure length 576
sequence length 589
ec nomenclature
pdb deposition date 2003-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00593 TonB_dep_Rec TonB dependent receptor
A PF07715 Plug TonB-dependent Receptor Plug Domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.170.20 Mainly Beta Beta Barrel Maltoporin; Chain A TonB-dependent receptor, beta-barrel domain 1nqgA02
2.170.130.10 Mainly Beta Beta Complex Ferric Hydroxamate Uptake Protein; Chain A, domain 1 TonB-dependent receptor, plug domain 1nqgA01
1XKHA 3RGNA 2W77A 4CU4A 1NQFA 1BY5A 2GRXA 4RDTA 3EFMA 4B7OA 1NQGA 3CSLA 3V8XA 2W6UA 1PNZA 4EPAA 1NQEA 1NQHA 3M8DA 5FOKA 2W78A 3CSNA 2GSKA 2O5PA 4AIPA 2HDIA 1QKCA 1KMOA 3QLBA 3FHHA 3V89A 4AIQA 1PO3A 1FI1A 1KMPA 1QFGA 1QFFA 1QJQA 1FCPA 1UJWA 2W6TA 4RDRA 2HDFA 2FCPA 2W76A 2IAHA 2GUFA 3DDRA 3M8BA 3RGMA 1FEPA 2YSUA 2W75A 2W16A 1PO0A 1BY3A 1XKWA
chains in the Genus database with same CATH superfamily
1XKHA 3RGNA 2W77A 1MPRA 4CU4A 1NQFA 1BY5A 2GRXA 4RDTA 1JBIA 3EFMA 4B7OA 1NQGA 1A0SP 3CSLA 3V8XA 1MPNA 2W6UA 1PNZA 4EPAA 1NQEA 1NQHA 1XKWA 3M8DA 5FOKA 2W78A 1MPMA 3CSNA 2GSKA 2O5PA 4AIPA 1QKCA 2HDIA 1A0TP 1KMOA 3QLBA 3FHHA 3V89A 4AIQA 1PO3A 1FI1A 1OH2Q 1KMPA 1QFGA 1QFFA 1MPOA 1OH2P 1QJQA 1FCPA 1UJWA 2W6TA 4RDRA 2HDFA 2FCPA 2W76A 2MPRA 1AF6A 2IAHA 1MALA 2GUFA 3DDRA 3M8BA 3RGMA 1FEPA 2YSUA 2W75A 2W16A 1PO0A 1BY3A 1MPQA
chains in the Genus database with same CATH topology
1XKHA 3RGNA 2W77A 4CU4A 1NQFA 1BY5A 2GRXA 4RDTA 3EFMA 4B7OA 1NQGA 3CSLA 3V8XA 2W6UA 1PNZA 4EPAA 1NQEA 1NQHA 3M8DA 5FOKA 2W78A 3CSNA 2GSKA 2O5PA 4AIPA 2HDIA 1QKCA 1KMOA 3QLBA 3FHHA 3V89A 4AIQA 1PO3A 1FI1A 1KMPA 1QFGA 1QFFA 1QJQA 1FCPA 1UJWA 2W6TA 4RDRA 2HDFA 2FCPA 2W76A 2IAHA 2GUFA 3DDRA 3M8BA 3RGMA 1FEPA 2YSUA 2W75A 2W16A 1PO0A 1BY3A 1XKWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XKH A;  3RGN A;  2W77 A;  4CU4 A;  1NQF A;  1BY5 A;  2GRX A;  4RDT A;  3EFM A;  4B7O A;  1NQG A;  3CSL A;  3V8X A;  2W6U A;  1PNZ A;  4EPA A;  1NQE A;  1NQH A;  3M8D A;  5FOK A;  2W78 A;  3CSN A;  2GSK A;  2O5P A;  4AIP A;  2HDI A;  1QKC A;  1KMO A;  3QLB A;  3FHH A;  3V89 A;  4AIQ A;  1PO3 A;  1FI1 A;  1KMP A;  1QFG A;  1QFF A;  1QJQ A;  1FCP A;  1UJW A;  2W6T A;  4RDR A;  2HDF A;  2FCP A;  2W76 A;  2IAH A;  2GUF A;  3DDR A;  3M8B A;  3RGM A;  1FEP A;  2YSU A;  2W75 A;  2W16 A;  1PO0 A;  1BY3 A;  1XKW A; 
#chains in the Genus database with same CATH topology
 1XKH A;  3RGN A;  2W77 A;  1MPR A;  4CU4 A;  1NQF A;  1BY5 A;  2GRX A;  4RDT A;  1JBI A;  3EFM A;  4B7O A;  1NQG A;  1A0S P;  3CSL A;  3V8X A;  1MPN A;  2W6U A;  1PNZ A;  4EPA A;  1NQE A;  1NQH A;  1XKW A;  3M8D A;  5FOK A;  2W78 A;  1MPM A;  3CSN A;  2GSK A;  2O5P A;  4AIP A;  1QKC A;  2HDI A;  1A0T P;  1KMO A;  3QLB A;  3FHH A;  3V89 A;  4AIQ A;  1PO3 A;  1FI1 A;  1OH2 Q;  1KMP A;  1QFG A;  1QFF A;  1MPO A;  1OH2 P;  1QJQ A;  1FCP A;  1UJW A;  2W6T A;  4RDR A;  2HDF A;  2FCP A;  2W76 A;  2MPR A;  1AF6 A;  2IAH A;  1MAL A;  2GUF A;  3DDR A;  3M8B A;  3RGM A;  1FEP A;  2YSU A;  2W75 A;  2W16 A;  1PO0 A;  1BY3 A;  1MPQ A; 
#chains in the Genus database with same CATH homology
 1XKH A;  3RGN A;  2W77 A;  4CU4 A;  1NQF A;  1BY5 A;  2GRX A;  4RDT A;  3EFM A;  4B7O A;  1NQG A;  3CSL A;  3V8X A;  2W6U A;  1PNZ A;  4EPA A;  1NQE A;  1NQH A;  3M8D A;  5FOK A;  2W78 A;  3CSN A;  2GSK A;  2O5P A;  4AIP A;  2HDI A;  1QKC A;  1KMO A;  3QLB A;  3FHH A;  3V89 A;  4AIQ A;  1PO3 A;  1FI1 A;  1KMP A;  1QFG A;  1QFF A;  1QJQ A;  1FCP A;  1UJW A;  2W6T A;  4RDR A;  2HDF A;  2FCP A;  2W76 A;  2IAH A;  2GUF A;  3DDR A;  3M8B A;  3RGM A;  1FEP A;  2YSU A;  2W75 A;  2W16 A;  1PO0 A;  1BY3 A;  1XKW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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