1R9TE

Rna polymerase ii strand separated elongation complex, mismatched nucleotide
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
molecule keywords RNA strand
total genus 39
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2003-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 1r9tE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 1r9tE02
5M5WE 2NVQE 3HKZH 2JA5E 2NVTE 3GTLE 2JA6E 2YU9E 5IYCE 2E2JE 3PO2E 1K83E 1TWFE 4AYBH 2B63E 4A93E 3K7AE 1TWAE 3M4OE 4A3KE 3S17E 3HOUE 5M5XE 3GTJE 3HOYE 3S1RE 1Y1WE 2VUME 1WCME 4C3IE 2WB1H 4A3GE 2R93E 2PMZH 4Y7NE 3M3YE 3I4ME 4X6AE 3GTOE 5C4XE 1Y1VE 3RZOE 1TWCE 3S2HE 5C3EE 1TWGE 2WAQH 4A3CE 2NVYE 5IP7E 3HOZE 2JA8E 5FJ8E 4Y52E 3HOVE 3GTPE 1I6HE 4A3BE 4BY7E 5IYBE 4C3HE 1I3QE 3I4NE 5M5YE 3HOWE 1DZFA 4BY1E 4C3JE 3S1NE 3H0GE 3PO3E 2E2IE 3S1QE 2NVXE 1TWHE 5C44E 3S15E 4C2ME 4BXXE 3S2DE 4BBSE 4A3IE 3H3VF 3S1ME 4A3EE 5M3ME 3S14E 5IP9E 4A3DE 4A3LE 1SFOE 3GTQE 2E2HE 2JA7E 3GTME 3S16E 2Y0SH 5IYDE 2R7ZE 3RZDE 3CQZE 4A3JE 4QIWH 3GTKE 3HOXE 5FLME 4BBRE 5C4JE 3GTGE 1I50E 2R92E 1EIKA 1R9TE 4A3ME 5M3FE 4A3FE 3FKIE
chains in the Genus database with same CATH superfamily
5M5WE 2NVQE 4MQ9E 3HKZH 4A93F 2JA5E 1TWAF 2NVTE 3GTLE 1I6VE 2NVYF 3M4OF 2JA6E 2YU9E 5IYCE 3HOVF 3GTPF 4A3KF 2E2JE 3PO2E 2A6HE 2WB1I 1K83E 1TWFE 5TMCE 4BY7F 2B63E 4AYBH 5M5XF 3HOUF 1HQME 4XSXE 5IYBF 4A93E 3K7AE 5D4EE 1TWAE 4QIWK 4C3HF 1I3QF 3S1RF 3M4OE 5M5YF 3I4NF 2VUMF 1WCMF 4YG2E 4A3KE 3S17E 4C3IF 4A3GF 1SMYE 3HOUE 5M5XE 4YFKE 4Y7NF 3GTJE 3HOYE 3S1RE 4JK1E 1Y1WE 4MEXE 2E2IF 2BE5E 2VUME 1WCME 4X6AF 2A69E 1YNJK 5C44F 4C3IE 2WB1H 4A3GE 2R93E 2KRXA 2PMZH 2NVXF 3H3VG 4Y7NE 3S2DF 4KN4E 1TWCF 3RZOF 3S2HF 5C3EF 3DXJE 3M3YE 3I4ME 4X6AE 4G7HE 3GTOE 1QKLA 4XSZE 5C4XE 4LK0E 4GZYE 4A3CF 5IP7F 1Y1VE 2CW0E 4LJZE 3RZOE 1TWCE 4MEYE 3S2HE 1YNNK 4Y52F 5FJ8F 5C3EE 4YFNE 2JA8F 1TWGE 4A3EF 2WAQH 4A3CE 2NVYE 5IP7E 3S14F 3HOWF 3HOZE 5E17E 5TMFE 5BYHE 2JA8E 5FJ8E 4Y52E 3HOVE 3GTPE 1SFOF 1I6HE 3GTQF 4A3BE 2E2HF 4A3LF 4BY7E 4BY1F 5IYBE 4C3JF 3S1NF 4C3HE 1I3QE 3I4NE 3H0GF 5M5YE 3HOWE 4OIRE 3S16F 3PO3F 1DZFA 3S1QF 3S15F 1TWHF 4Q5SE 4BY1E 4C2MF 4BXXF 4BBSF 4C3JE 3HKZK 3S1NE 3H0GE 3PO3E 4A3IF 2E2IE 4XLNE 4XLPE 3CQZF 5D4DE 3S1QE 2NVXE 1TWHE 5C44E 3S15E 4C2ME 4BXXE 3S2DE 3S1MF 4AYBK 4BBSE 4A3BF 1IW7E 1I6HF 4A3IE 3GTGF 5M3MF 3H3VF 3S1ME 1TWGF 2Y0SI 5IP9F 4G7OE 4A3DF 4Q4ZE 5D4CE 3FKIF 4A3EE 5M3ME 2JA7F 4LK1E 3GTMF 3S14E 2PMZK 5IP9E 2YU9F 4A3DE 5IYCF 4OINE 2E2JF 4A3LE 2A68E 1SFOE 3GTQE 4ZH4E 4G7ZE 2E2HE 2B63F 3PO2F 5IYDF 3EQLE 3WODE 2R7ZF 3K7AF 2JA7E 3GTME 3RZDF 2O5JE 3S16E 2Y0SH 2A6EE 4A3JF 3S17F 2PPBE 3GTKF 3HOXF 5IPLE 5IYDE 2R7ZE 4YFXE 5FLMF 4BBRF 3GTJF 1ZYRE 2WAQK 1Y1WF 3HOYF 5C4JF 3RZDE 3HOZF 4OIOE 3CQZE 4A3JE 4QIWH 2R93F 1I50F 3GTKE 3HOXE 2R92F 1R9TF 4KN7E 5FLME 4BBRE 4KMUE 4LLGE 4A3MF 5M3FF 5C4JE 2O5IE 3M3YF 4A3FF 3I4MF 3GTOF 5M5WF 2NVQF 2JA5F 3GTGE 1I50E 5C4XF 2R92E 2NVTF 4OIPE 3GTLF 1R9TE 1Y1VF 1EIKA 2JA6F 4OIQE 4A3ME 5M3FE 5E18E 1K83F 1TWFF 4A3FE 3FKIE
chains in the Genus database with same CATH topology
5M5WE 2NVQE 3HKZH 2JA5E 2NVTE 3GTLE 2JA6E 2YU9E 5IYCE 2E2JE 3PO2E 1K83E 1TWFE 4AYBH 2B63E 4A93E 3K7AE 1TWAE 3M4OE 4A3KE 3S17E 3HOUE 5M5XE 3GTJE 3HOYE 3S1RE 1Y1WE 2VUME 1WCME 4C3IE 2WB1H 4A3GE 2R93E 2PMZH 4Y7NE 3M3YE 3I4ME 4X6AE 3GTOE 5C4XE 1Y1VE 3RZOE 1TWCE 3S2HE 5C3EE 1TWGE 2WAQH 4A3CE 2NVYE 5IP7E 3HOZE 2JA8E 5FJ8E 4Y52E 3HOVE 3GTPE 1I6HE 4A3BE 4BY7E 5IYBE 4C3HE 1I3QE 3I4NE 5M5YE 3HOWE 1DZFA 4BY1E 4C3JE 3S1NE 3H0GE 3PO3E 2E2IE 3S1QE 2NVXE 1TWHE 5C44E 3S15E 4C2ME 4BXXE 3S2DE 4BBSE 4A3IE 3H3VF 3S1ME 4A3EE 5M3ME 3S14E 5IP9E 4A3DE 4A3LE 1SFOE 3GTQE 2E2HE 2JA7E 3GTME 3S16E 2Y0SH 5IYDE 2R7ZE 3RZDE 3CQZE 4A3JE 4QIWH 3GTKE 3HOXE 5FLME 4BBRE 5C4JE 3GTGE 1I50E 2R92E 1EIKA 1R9TE 4A3ME 5M3FE 4A3FE 3FKIE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5M5W E;  2NVQ E;  3HKZ H;  2JA5 E;  2NVT E;  3GTL E;  2JA6 E;  2YU9 E;  5IYC E;  2E2J E;  3PO2 E;  1K83 E;  1TWF E;  4AYB H;  2B63 E;  4A93 E;  3K7A E;  1TWA E;  3M4O E;  4A3K E;  3S17 E;  3HOU E;  5M5X E;  3GTJ E;  3HOY E;  3S1R E;  1Y1W E;  2VUM E;  1WCM E;  4C3I E;  2WB1 H;  4A3G E;  2R93 E;  2PMZ H;  4Y7N E;  3M3Y E;  3I4M E;  4X6A E;  3GTO E;  5C4X E;  1Y1V E;  3RZO E;  1TWC E;  3S2H E;  5C3E E;  1TWG E;  2WAQ H;  4A3C E;  2NVY E;  5IP7 E;  3HOZ E;  2JA8 E;  5FJ8 E;  4Y52 E;  3HOV E;  3GTP E;  1I6H E;  4A3B E;  4BY7 E;  5IYB E;  4C3H E;  1I3Q E;  3I4N E;  5M5Y E;  3HOW E;  1DZF A;  4BY1 E;  4C3J E;  3S1N E;  3H0G E;  3PO3 E;  2E2I E;  3S1Q E;  2NVX E;  1TWH E;  5C44 E;  3S15 E;  4C2M E;  4BXX E;  3S2D E;  4BBS E;  4A3I E;  3H3V F;  3S1M E;  4A3E E;  5M3M E;  3S14 E;  5IP9 E;  4A3D E;  4A3L E;  1SFO E;  3GTQ E;  2E2H E;  2JA7 E;  3GTM E;  3S16 E;  2Y0S H;  5IYD E;  2R7Z E;  3RZD E;  3CQZ E;  4A3J E;  4QIW H;  3GTK E;  3HOX E;  5FLM E;  4BBR E;  5C4J E;  3GTG E;  1I50 E;  2R92 E;  1EIK A;  1R9T E;  4A3M E;  5M3F E;  4A3F E;  3FKI E; 
#chains in the Genus database with same CATH topology
 5M5W E;  2NVQ E;  4MQ9 E;  3HKZ H;  4A93 F;  2JA5 E;  1TWA F;  2NVT E;  3GTL E;  1I6V E;  2NVY F;  3M4O F;  2JA6 E;  2YU9 E;  5IYC E;  3HOV F;  3GTP F;  4A3K F;  2E2J E;  3PO2 E;  2A6H E;  2WB1 I;  1K83 E;  1TWF E;  5TMC E;  4BY7 F;  2B63 E;  4AYB H;  5M5X F;  3HOU F;  1HQM E;  4XSX E;  5IYB F;  4A93 E;  3K7A E;  5D4E E;  1TWA E;  4QIW K;  4C3H F;  1I3Q F;  3S1R F;  3M4O E;  5M5Y F;  3I4N F;  2VUM F;  1WCM F;  4YG2 E;  4A3K E;  3S17 E;  4C3I F;  4A3G F;  1SMY E;  3HOU E;  5M5X E;  4YFK E;  4Y7N F;  3GTJ E;  3HOY E;  3S1R E;  4JK1 E;  1Y1W E;  4MEX E;  2E2I F;  2BE5 E;  2VUM E;  1WCM E;  4X6A F;  2A69 E;  1YNJ K;  5C44 F;  4C3I E;  2WB1 H;  4A3G E;  2R93 E;  2KRX A;  2PMZ H;  2NVX F;  3H3V G;  4Y7N E;  3S2D F;  4KN4 E;  1TWC F;  3RZO F;  3S2H F;  5C3E F;  3DXJ E;  3M3Y E;  3I4M E;  4X6A E;  4G7H E;  3GTO E;  1QKL A;  4XSZ E;  5C4X E;  4LK0 E;  4GZY E;  4A3C F;  5IP7 F;  1Y1V E;  2CW0 E;  4LJZ E;  3RZO E;  1TWC E;  4MEY E;  3S2H E;  1YNN K;  4Y52 F;  5FJ8 F;  5C3E E;  4YFN E;  2JA8 F;  1TWG E;  4A3E F;  2WAQ H;  4A3C E;  2NVY E;  5IP7 E;  3S14 F;  3HOW F;  3HOZ E;  5E17 E;  5TMF E;  5BYH E;  2JA8 E;  5FJ8 E;  4Y52 E;  3HOV E;  3GTP E;  1SFO F;  1I6H E;  3GTQ F;  4A3B E;  2E2H F;  4A3L F;  4BY7 E;  4BY1 F;  5IYB E;  4C3J F;  3S1N F;  4C3H E;  1I3Q E;  3I4N E;  3H0G F;  5M5Y E;  3HOW E;  4OIR E;  3S16 F;  3PO3 F;  1DZF A;  3S1Q F;  3S15 F;  1TWH F;  4Q5S E;  4BY1 E;  4C2M F;  4BXX F;  4BBS F;  4C3J E;  3HKZ K;  3S1N E;  3H0G E;  3PO3 E;  4A3I F;  2E2I E;  4XLN E;  4XLP E;  3CQZ F;  5D4D E;  3S1Q E;  2NVX E;  1TWH E;  5C44 E;  3S15 E;  4C2M E;  4BXX E;  3S2D E;  3S1M F;  4AYB K;  4BBS E;  4A3B F;  1IW7 E;  1I6H F;  4A3I E;  3GTG F;  5M3M F;  3H3V F;  3S1M E;  1TWG F;  2Y0S I;  5IP9 F;  4G7O E;  4A3D F;  4Q4Z E;  5D4C E;  3FKI F;  4A3E E;  5M3M E;  2JA7 F;  4LK1 E;  3GTM F;  3S14 E;  2PMZ K;  5IP9 E;  2YU9 F;  4A3D E;  5IYC F;  4OIN E;  2E2J F;  4A3L E;  2A68 E;  1SFO E;  3GTQ E;  4ZH4 E;  4G7Z E;  2E2H E;  2B63 F;  3PO2 F;  5IYD F;  3EQL E;  3WOD E;  2R7Z F;  3K7A F;  2JA7 E;  3GTM E;  3RZD F;  2O5J E;  3S16 E;  2Y0S H;  2A6E E;  4A3J F;  3S17 F;  2PPB E;  3GTK F;  3HOX F;  5IPL E;  5IYD E;  2R7Z E;  4YFX E;  5FLM F;  4BBR F;  3GTJ F;  1ZYR E;  2WAQ K;  1Y1W F;  3HOY F;  5C4J F;  3RZD E;  3HOZ F;  4OIO E;  3CQZ E;  4A3J E;  4QIW H;  2R93 F;  1I50 F;  3GTK E;  3HOX E;  2R92 F;  1R9T F;  4KN7 E;  5FLM E;  4BBR E;  4KMU E;  4LLG E;  4A3M F;  5M3F F;  5C4J E;  2O5I E;  3M3Y F;  4A3F F;  3I4M F;  3GTO F;  5M5W F;  2NVQ F;  2JA5 F;  3GTG E;  1I50 E;  5C4X F;  2R92 E;  2NVT F;  4OIP E;  3GTL F;  1R9T E;  1Y1V F;  1EIK A;  2JA6 F;  4OIQ E;  4A3M E;  5M3F E;  5E18 E;  1K83 F;  1TWF F;  4A3F E;  3FKI E; 
#chains in the Genus database with same CATH homology
 5M5W E;  2NVQ E;  3HKZ H;  2JA5 E;  2NVT E;  3GTL E;  2JA6 E;  2YU9 E;  5IYC E;  2E2J E;  3PO2 E;  1K83 E;  1TWF E;  4AYB H;  2B63 E;  4A93 E;  3K7A E;  1TWA E;  3M4O E;  4A3K E;  3S17 E;  3HOU E;  5M5X E;  3GTJ E;  3HOY E;  3S1R E;  1Y1W E;  2VUM E;  1WCM E;  4C3I E;  2WB1 H;  4A3G E;  2R93 E;  2PMZ H;  4Y7N E;  3M3Y E;  3I4M E;  4X6A E;  3GTO E;  5C4X E;  1Y1V E;  3RZO E;  1TWC E;  3S2H E;  5C3E E;  1TWG E;  2WAQ H;  4A3C E;  2NVY E;  5IP7 E;  3HOZ E;  2JA8 E;  5FJ8 E;  4Y52 E;  3HOV E;  3GTP E;  1I6H E;  4A3B E;  4BY7 E;  5IYB E;  4C3H E;  1I3Q E;  3I4N E;  5M5Y E;  3HOW E;  1DZF A;  4BY1 E;  4C3J E;  3S1N E;  3H0G E;  3PO3 E;  2E2I E;  3S1Q E;  2NVX E;  1TWH E;  5C44 E;  3S15 E;  4C2M E;  4BXX E;  3S2D E;  4BBS E;  4A3I E;  3H3V F;  3S1M E;  4A3E E;  5M3M E;  3S14 E;  5IP9 E;  4A3D E;  4A3L E;  1SFO E;  3GTQ E;  2E2H E;  2JA7 E;  3GTM E;  3S16 E;  2Y0S H;  5IYD E;  2R7Z E;  3RZD E;  3CQZ E;  4A3J E;  4QIW H;  3GTK E;  3HOX E;  5FLM E;  4BBR E;  5C4J E;  3GTG E;  1I50 E;  2R92 E;  1EIK A;  1R9T E;  4A3M E;  5M3F E;  4A3F E;  3FKI E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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