1RTGA

C-terminal domain (haemopexin-like domain) of human matrix metalloproteinase-2
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
203
structure length
203
Chain Sequence
TPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The C-terminal (haemopexin-like) domain structure of human gelatinase A (MMP2): structural implications for its function.
pubmed doi rcsb
molecule keywords HUMAN GELATINASE A
molecule tags Metalloprotease
total genus 40
structure length 203
sequence length 203
ec nomenclature ec 3.4.24.24: Gelatinase A.
pdb deposition date 1995-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 1rtgA00
1FBLA 4FU4A 1CK7A 1HXNA 4YEHA 4RT6B 3S18A 4G0DA 4FVLA 1PEXA 1QJSA 2JXYA 3OYOA 1GENA 3V6NA 2CLTA 4HSDA 1SU3A 1ITVA 1QHUA 4AUOA 3LP9A 4LL2A 3C7XA 1GXDA 4OEIA 1RTGA 3BA0A 2MQSA
chains in the Genus database with same CATH superfamily
1FBLA 4FU4A 1CK7A 1HXNA 4YEHA 4RT6B 3S18A 4G0DA 4FVLA 1PEXA 1QJSA 2JXYA 3OYOA 1GENA 3V6NA 2CLTA 4HSDA 1SU3A 1ITVA 1QHUA 4AUOA 3LP9A 4LL2A 3C7XA 1GXDA 4OEIA 1RTGA 3BA0A 2MQSA
chains in the Genus database with same CATH topology
1FBLA 4FU4A 1CK7A 1HXNA 4YEHA 4RT6B 3S18A 4G0DA 4FVLA 1PEXA 1QJSA 2JXYA 3OYOA 1GENA 3V6NA 2CLTA 4HSDA 1SU3A 1ITVA 1QHUA 4AUOA 3LP9A 4LL2A 3C7XA 1GXDA 4OEIA 1RTGA 3BA0A 2MQSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FBL A;  4FU4 A;  1CK7 A;  1HXN A;  4YEH A;  4RT6 B;  3S18 A;  4G0D A;  4FVL A;  1PEX A;  1QJS A;  2JXY A;  3OYO A;  1GEN A;  3V6N A;  2CLT A;  4HSD A;  1SU3 A;  1ITV A;  1QHU A;  4AUO A;  3LP9 A;  4LL2 A;  3C7X A;  1GXD A;  4OEI A;  1RTG A;  3BA0 A;  2MQS A; 
#chains in the Genus database with same CATH topology
 1FBL A;  4FU4 A;  1CK7 A;  1HXN A;  4YEH A;  4RT6 B;  3S18 A;  4G0D A;  4FVL A;  1PEX A;  1QJS A;  2JXY A;  3OYO A;  1GEN A;  3V6N A;  2CLT A;  4HSD A;  1SU3 A;  1ITV A;  1QHU A;  4AUO A;  3LP9 A;  4LL2 A;  3C7X A;  1GXD A;  4OEI A;  1RTG A;  3BA0 A;  2MQS A; 
#chains in the Genus database with same CATH homology
 1FBL A;  4FU4 A;  1CK7 A;  1HXN A;  4YEH A;  4RT6 B;  3S18 A;  4G0D A;  4FVL A;  1PEX A;  1QJS A;  2JXY A;  3OYO A;  1GEN A;  3V6N A;  2CLT A;  4HSD A;  1SU3 A;  1ITV A;  1QHU A;  4AUO A;  3LP9 A;  4LL2 A;  3C7X A;  1GXD A;  4OEI A;  1RTG A;  3BA0 A;  2MQS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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