1SFOE

Rna polymerase ii strand separated elongation complex
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
molecule keywords RNA STRAND
total genus 44
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2004-02-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 1sfoE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 1sfoE02
3M4OE 1EIKA 1TWGE 3RZOE 1R9TE 3GTPE 1I6HE 3S1QE 3HOUE 3K7AE 2WB1H 2YU9E 4C3JE 2PMZH 3GTME 5FJ8E 2E2IE 4A3ME 2VUME 3I4ME 1K83E 3S1NE 1I3QE 4BBRE 4QIWH 2Y0SH 3GTLE 3H0GE 3GTJE 4C3HE 1TWCE 2B63E 3HOWE 5C4JE 2R7ZE 5M5WE 4Y52E 1TWFE 4A3EE 2R92E 4A3BE 5C4XE 3H3VF 3HOZE 3PO3E 5IP7E 1DZFA 4A3GE 1SFOE 1TWHE 3GTKE 4Y7NE 2NVYE 5M5YE 5M3FE 3S1RE 5IP9E 4A3LE 5C3EE 2JA5E 3S1ME 3GTQE 3HOYE 5M5XE 5C44E 5IYDE 4A3DE 1Y1WE 5IYBE 3HKZH 3I4NE 3S17E 3CQZE 4BBSE 3M3YE 2NVXE 4A3FE 3HOXE 3FKIE 3S16E 5IYCE 5M3ME 4A3JE 1Y1VE 5FLME 4BY1E 3GTGE 2NVQE 3GTOE 4A93E 3HOVE 1WCME 1I50E 3S2DE 2JA8E 4C3IE 4C2ME 4AYBH 4A3CE 2JA6E 4A3IE 2E2JE 4A3KE 1TWAE 3S2HE 2JA7E 3PO2E 2R93E 3S14E 4X6AE 3S15E 2WAQH 2NVTE 3RZDE 4BY7E 2E2HE 4BXXE
chains in the Genus database with same CATH superfamily
1I6VE 4QIWK 3M4OE 5M5WF 1EIKA 1TWGE 4XSZE 3RZOE 3GTOF 2YU9F 4C3JF 1R9TE 3GTPE 1I6HE 5FJ8F 4A3EF 2R92F 1HQME 4MQ9E 3S1QE 2E2IF 4A3BF 3HOUE 4A3MF 3K7AE 2WB1H 4LJZE 2YU9E 4C3JE 2PMZH 4KN7E 4XSXE 3H3VG 3GTME 3PO3F 5IP7F 5D4EE 5FJ8E 1K83F 2E2IE 3S1NF 4A3ME 2VUME 4MEYE 5E18E 4YFXE 4G7ZE 3EQLE 3I4ME 4BBRF 4Y7NF 5IPLE 5M5YF 1K83E 3S1RF 3S1NE 4Q5SE 3GTLF 1I3QE 3H0GF 4C3HF 5C3EF 2JA5F 3S1MF 3GTQF 1TWCF 2A69E 4BBRE 4QIWH 2B63F 3HOWF 3HOYF 5C4JF 2R7ZF 5IYDF 1Y1WF 2Y0SH 3GTLE 3H0GE 3GTJE 4C3HE 2KRXA 3CQZF 4BBSF 4Y52F 1TWCE 1TWFF 2B63E 3HOWE 4YFKE 4LLGE 4A3FF 5D4DE 5C4JE 2R7ZE 5M5WE 5C4XF 4LK1E 3S16F 3HOZF 5IYCF 4Y52E 3HKZK 1TWFE 4OIPE 4A3EE 2R92E 1Y1VF 4A3GF 4A3BE 1SMYE 1SFOF 5FLMF 5C4XE 4A93F 3H3VF 1TWHF 3HOZE 3GTKF 4KN4E 4Q4ZE 3PO3E 2NVYF 5IP7E 1I50F 1DZFA 4A3GE 1SFOE 5M3FF 5IP9F 4A3LF 2O5JE 1TWHE 4XLPE 3GTKE 4OIOE 4OIRE 4Y7NE 2NVYE 2A6EE 5M5YE 1TWAF 4ZH4E 5M5XF 1ZYRE 5C44F 4A3DF 5M3FE 3S1RE 3WODE 5IYBF 5IP9E 3I4NF 4A3LE 5C3EE 3S17F 2JA5E 3S1ME 3GTQE 4AYBK 2JA7F 3HOYE 3M3YF 2NVXF 2R93F 1YNNK 4YFNE 5M5XE 1QKLA 3S14F 5C44E 5IYDE 4A3DE 1Y1WE 4XLNE 5IYBE 3FKIF 3I4NE 3HKZH 3S17E 4LK0E 3HOXF 3CQZE 4BBSE 3S15F 2A68E 4BY7F 2BE5E 5M3MF 4A3JF 3RZDF 3M3YE 2NVXE 4MEXE 2E2HF 4BXXF 4A3FE 5TMCE 3M4OF 4BY1F 3GTGF 3HOXE 3FKIE 1TWGF 2WB1I 2CW0E 3S16E 4KMUE 5D4CE 2NVQF 5IYCE 1R9TF 3HOVF 1WCMF 1I6HF 3S2DF 5M3ME 4A3JE 2JA8F 1Y1VE 2WAQK 4C2MF 4C3IF 4G7OE 3S1QF 5FLME 3HOUF 4BY1E 3GTGE 4G7HE 2NVQE 3GTOE 4A93E 3K7AF 3HOVE 4OIQE 2JA6F 4A3CF 1WCME 3DXJE 4A3IF 1I50E 3S2DE 2JA8E 4A3KF 2E2JF 3GTMF 4C3IE 4C2ME 1YNJK 3S2HF 1IW7E 2VUMF 4AYBH 5TMFE 4A3CE 2JA6E 3I4MF 4A3IE 2E2JE 3PO2F 4A3KE 1TWAE 4GZYE 2PMZK 2PPBE 3S2HE 4X6AF 2A6HE 2Y0SI 1I3QF 2NVTF 2JA7E 3PO2E 2R93E 4YG2E 3S14E 5E17E 4X6AE 3S15E 3RZOF 3GTJF 2WAQH 4OINE 3GTPF 5BYHE 2NVTE 3RZDE 4BY7E 2E2HE 2O5IE 4BXXE 4JK1E
chains in the Genus database with same CATH topology
3M4OE 1EIKA 1TWGE 3RZOE 1R9TE 3GTPE 1I6HE 3S1QE 3HOUE 3K7AE 2WB1H 2YU9E 4C3JE 2PMZH 3GTME 5FJ8E 2E2IE 4A3ME 2VUME 3I4ME 1K83E 3S1NE 1I3QE 4BBRE 4QIWH 2Y0SH 3GTLE 3H0GE 3GTJE 4C3HE 1TWCE 2B63E 3HOWE 5C4JE 2R7ZE 5M5WE 4Y52E 1TWFE 4A3EE 2R92E 4A3BE 5C4XE 3H3VF 3HOZE 3PO3E 5IP7E 1DZFA 4A3GE 1SFOE 1TWHE 3GTKE 4Y7NE 2NVYE 5M5YE 5M3FE 3S1RE 5IP9E 4A3LE 5C3EE 2JA5E 3S1ME 3GTQE 3HOYE 5M5XE 5C44E 5IYDE 4A3DE 1Y1WE 5IYBE 3HKZH 3I4NE 3S17E 3CQZE 4BBSE 3M3YE 2NVXE 4A3FE 3HOXE 3FKIE 3S16E 5IYCE 5M3ME 4A3JE 1Y1VE 5FLME 4BY1E 3GTGE 2NVQE 3GTOE 4A93E 3HOVE 1WCME 1I50E 3S2DE 2JA8E 4C3IE 4C2ME 4AYBH 4A3CE 2JA6E 4A3IE 2E2JE 4A3KE 1TWAE 3S2HE 2JA7E 3PO2E 2R93E 3S14E 4X6AE 3S15E 2WAQH 2NVTE 3RZDE 4BY7E 2E2HE 4BXXE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M4O E;  1EIK A;  1TWG E;  3RZO E;  1R9T E;  3GTP E;  1I6H E;  3S1Q E;  3HOU E;  3K7A E;  2WB1 H;  2YU9 E;  4C3J E;  2PMZ H;  3GTM E;  5FJ8 E;  2E2I E;  4A3M E;  2VUM E;  3I4M E;  1K83 E;  3S1N E;  1I3Q E;  4BBR E;  4QIW H;  2Y0S H;  3GTL E;  3H0G E;  3GTJ E;  4C3H E;  1TWC E;  2B63 E;  3HOW E;  5C4J E;  2R7Z E;  5M5W E;  4Y52 E;  1TWF E;  4A3E E;  2R92 E;  4A3B E;  5C4X E;  3H3V F;  3HOZ E;  3PO3 E;  5IP7 E;  1DZF A;  4A3G E;  1SFO E;  1TWH E;  3GTK E;  4Y7N E;  2NVY E;  5M5Y E;  5M3F E;  3S1R E;  5IP9 E;  4A3L E;  5C3E E;  2JA5 E;  3S1M E;  3GTQ E;  3HOY E;  5M5X E;  5C44 E;  5IYD E;  4A3D E;  1Y1W E;  5IYB E;  3HKZ H;  3I4N E;  3S17 E;  3CQZ E;  4BBS E;  3M3Y E;  2NVX E;  4A3F E;  3HOX E;  3FKI E;  3S16 E;  5IYC E;  5M3M E;  4A3J E;  1Y1V E;  5FLM E;  4BY1 E;  3GTG E;  2NVQ E;  3GTO E;  4A93 E;  3HOV E;  1WCM E;  1I50 E;  3S2D E;  2JA8 E;  4C3I E;  4C2M E;  4AYB H;  4A3C E;  2JA6 E;  4A3I E;  2E2J E;  4A3K E;  1TWA E;  3S2H E;  2JA7 E;  3PO2 E;  2R93 E;  3S14 E;  4X6A E;  3S15 E;  2WAQ H;  2NVT E;  3RZD E;  4BY7 E;  2E2H E;  4BXX E; 
#chains in the Genus database with same CATH topology
 1I6V E;  4QIW K;  3M4O E;  5M5W F;  1EIK A;  1TWG E;  4XSZ E;  3RZO E;  3GTO F;  2YU9 F;  4C3J F;  1R9T E;  3GTP E;  1I6H E;  5FJ8 F;  4A3E F;  2R92 F;  1HQM E;  4MQ9 E;  3S1Q E;  2E2I F;  4A3B F;  3HOU E;  4A3M F;  3K7A E;  2WB1 H;  4LJZ E;  2YU9 E;  4C3J E;  2PMZ H;  4KN7 E;  4XSX E;  3H3V G;  3GTM E;  3PO3 F;  5IP7 F;  5D4E E;  5FJ8 E;  1K83 F;  2E2I E;  3S1N F;  4A3M E;  2VUM E;  4MEY E;  5E18 E;  4YFX E;  4G7Z E;  3EQL E;  3I4M E;  4BBR F;  4Y7N F;  5IPL E;  5M5Y F;  1K83 E;  3S1R F;  3S1N E;  4Q5S E;  3GTL F;  1I3Q E;  3H0G F;  4C3H F;  5C3E F;  2JA5 F;  3S1M F;  3GTQ F;  1TWC F;  2A69 E;  4BBR E;  4QIW H;  2B63 F;  3HOW F;  3HOY F;  5C4J F;  2R7Z F;  5IYD F;  1Y1W F;  2Y0S H;  3GTL E;  3H0G E;  3GTJ E;  4C3H E;  2KRX A;  3CQZ F;  4BBS F;  4Y52 F;  1TWC E;  1TWF F;  2B63 E;  3HOW E;  4YFK E;  4LLG E;  4A3F F;  5D4D E;  5C4J E;  2R7Z E;  5M5W E;  5C4X F;  4LK1 E;  3S16 F;  3HOZ F;  5IYC F;  4Y52 E;  3HKZ K;  1TWF E;  4OIP E;  4A3E E;  2R92 E;  1Y1V F;  4A3G F;  4A3B E;  1SMY E;  1SFO F;  5FLM F;  5C4X E;  4A93 F;  3H3V F;  1TWH F;  3HOZ E;  3GTK F;  4KN4 E;  4Q4Z E;  3PO3 E;  2NVY F;  5IP7 E;  1I50 F;  1DZF A;  4A3G E;  1SFO E;  5M3F F;  5IP9 F;  4A3L F;  2O5J E;  1TWH E;  4XLP E;  3GTK E;  4OIO E;  4OIR E;  4Y7N E;  2NVY E;  2A6E E;  5M5Y E;  1TWA F;  4ZH4 E;  5M5X F;  1ZYR E;  5C44 F;  4A3D F;  5M3F E;  3S1R E;  3WOD E;  5IYB F;  5IP9 E;  3I4N F;  4A3L E;  5C3E E;  3S17 F;  2JA5 E;  3S1M E;  3GTQ E;  4AYB K;  2JA7 F;  3HOY E;  3M3Y F;  2NVX F;  2R93 F;  1YNN K;  4YFN E;  5M5X E;  1QKL A;  3S14 F;  5C44 E;  5IYD E;  4A3D E;  1Y1W E;  4XLN E;  5IYB E;  3FKI F;  3I4N E;  3HKZ H;  3S17 E;  4LK0 E;  3HOX F;  3CQZ E;  4BBS E;  3S15 F;  2A68 E;  4BY7 F;  2BE5 E;  5M3M F;  4A3J F;  3RZD F;  3M3Y E;  2NVX E;  4MEX E;  2E2H F;  4BXX F;  4A3F E;  5TMC E;  3M4O F;  4BY1 F;  3GTG F;  3HOX E;  3FKI E;  1TWG F;  2WB1 I;  2CW0 E;  3S16 E;  4KMU E;  5D4C E;  2NVQ F;  5IYC E;  1R9T F;  3HOV F;  1WCM F;  1I6H F;  3S2D F;  5M3M E;  4A3J E;  2JA8 F;  1Y1V E;  2WAQ K;  4C2M F;  4C3I F;  4G7O E;  3S1Q F;  5FLM E;  3HOU F;  4BY1 E;  3GTG E;  4G7H E;  2NVQ E;  3GTO E;  4A93 E;  3K7A F;  3HOV E;  4OIQ E;  2JA6 F;  4A3C F;  1WCM E;  3DXJ E;  4A3I F;  1I50 E;  3S2D E;  2JA8 E;  4A3K F;  2E2J F;  3GTM F;  4C3I E;  4C2M E;  1YNJ K;  3S2H F;  1IW7 E;  2VUM F;  4AYB H;  5TMF E;  4A3C E;  2JA6 E;  3I4M F;  4A3I E;  2E2J E;  3PO2 F;  4A3K E;  1TWA E;  4GZY E;  2PMZ K;  2PPB E;  3S2H E;  4X6A F;  2A6H E;  2Y0S I;  1I3Q F;  2NVT F;  2JA7 E;  3PO2 E;  2R93 E;  4YG2 E;  3S14 E;  5E17 E;  4X6A E;  3S15 E;  3RZO F;  3GTJ F;  2WAQ H;  4OIN E;  3GTP F;  5BYH E;  2NVT E;  3RZD E;  4BY7 E;  2E2H E;  2O5I E;  4BXX E;  4JK1 E; 
#chains in the Genus database with same CATH homology
 3M4O E;  1EIK A;  1TWG E;  3RZO E;  1R9T E;  3GTP E;  1I6H E;  3S1Q E;  3HOU E;  3K7A E;  2WB1 H;  2YU9 E;  4C3J E;  2PMZ H;  3GTM E;  5FJ8 E;  2E2I E;  4A3M E;  2VUM E;  3I4M E;  1K83 E;  3S1N E;  1I3Q E;  4BBR E;  4QIW H;  2Y0S H;  3GTL E;  3H0G E;  3GTJ E;  4C3H E;  1TWC E;  2B63 E;  3HOW E;  5C4J E;  2R7Z E;  5M5W E;  4Y52 E;  1TWF E;  4A3E E;  2R92 E;  4A3B E;  5C4X E;  3H3V F;  3HOZ E;  3PO3 E;  5IP7 E;  1DZF A;  4A3G E;  1SFO E;  1TWH E;  3GTK E;  4Y7N E;  2NVY E;  5M5Y E;  5M3F E;  3S1R E;  5IP9 E;  4A3L E;  5C3E E;  2JA5 E;  3S1M E;  3GTQ E;  3HOY E;  5M5X E;  5C44 E;  5IYD E;  4A3D E;  1Y1W E;  5IYB E;  3HKZ H;  3I4N E;  3S17 E;  3CQZ E;  4BBS E;  3M3Y E;  2NVX E;  4A3F E;  3HOX E;  3FKI E;  3S16 E;  5IYC E;  5M3M E;  4A3J E;  1Y1V E;  5FLM E;  4BY1 E;  3GTG E;  2NVQ E;  3GTO E;  4A93 E;  3HOV E;  1WCM E;  1I50 E;  3S2D E;  2JA8 E;  4C3I E;  4C2M E;  4AYB H;  4A3C E;  2JA6 E;  4A3I E;  2E2J E;  4A3K E;  1TWA E;  3S2H E;  2JA7 E;  3PO2 E;  2R93 E;  3S14 E;  4X6A E;  3S15 E;  2WAQ H;  2NVT E;  3RZD E;  4BY7 E;  2E2H E;  4BXX E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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