1TWFF

Rna polymerase ii complexed with utp at 2.3 a resolution
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 25
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1twfF00
3S15F 2JA5F 4Q5SE 3K7AF 3GTGF 4OINE 2A6EE 3HOZF 5C4JF 4GZYE 4Y7NF 3RZDF 4A3CF 3S1MF 5D4CE 2VUMF 4G7OE 1TWAF 4BBRF 1QKLA 4A3FF 4MQ9E 1I3QF 2E2JF 4A3EF 1I6VE 3HOXF 2R7ZF 2JA7F 5IYDF 5M5XF 1Y1VF 3CQZF 5IP7F 5D4EE 4A3JF 1TWFF 2JA8F 2WB1I 1YNNK 3S2DF 4KMUE 3HOUF 5IPLE 3EQLE 1R9TF 2CW0E 5E17E 1SFOF 3GTMF 4A3DF 4G7HE 5IP9F 5M3FF 2NVYF 2NVQF 3I4MF 4A3KF 2R92F 4A3MF 3GTLF 3S2HF 5TMFE 1YNJK 3GTKF 3S1RF 4XLNE 5D4DE 1WCMF 2B63F 5TMCE 2PPBE 4YFKE 5C4XF 4A3IF 2R93F 2NVXF 2YU9F 5IYBF 3H3VG 2NVTF 3HOWF 3M4OF 4BBSF 1ZYRE 5M5WF 4KN4E 4LK1E 4MEXE 4LJZE 5C3EF 4XSZE 4A3BF 4A93F 2O5JE 3RZOF 1TWHF 1TWGF 2A68E 2E2IF 1I6HF 4G7ZE 4XSXE 3GTJF 3WODE 5E18E 5M3MF 3H0GF 4OIQE 3PO3F 2Y0SI 4BXXF 3DXJE 4BY7F 5M5YF 1K83F 4YFXE 2BE5E 4OIPE 4X6AF 1TWCF 1I50F 4LK0E 3S14F 4JK1E 4A3GF 3S16F 2E2HF 4C3JF 3HKZK 1HQME 3FKIF 5FJ8F 3HOVF 4ZH4E 4Q4ZE 1SMYE 3GTPF 1IW7E 4YFNE 2A6HE 5FLMF 3M3YF 4MEYE 4KN7E 3GTOF 3GTQF 5BYHE 3S1NF 4BY1F 2PMZK 4OIOE 3S17F 4C2MF 2O5IE 2JA6F 4OIRE 4Y52F 2WAQK 1Y1WF 4AYBK 3S1QF 4A3LF 5C44F 4C3IF 2A69E 3HOYF 4YG2E 5IYCF 3PO2F 4LLGE 4XLPE 4C3HF 3I4NF
chains in the Genus database with same CATH superfamily
4A93E 3S15F 2JA5F 4Q5SE 3K7AF 3RZOE 2WAQH 1TWHE 2Y0SH 3GTGF 1R9TE 1TWGE 4OINE 2A6EE 4A3DE 3HOZF 5C4JF 4GZYE 2NVYE 4Y7NF 3RZDF 3I4ME 5M3ME 3H0GE 4A3KE 4A3CF 3S1MF 1DZFA 5D4CE 2VUMF 3GTLE 3PO3E 1TWAF 4BBRF 4G7OE 1QKLA 4A3FF 5M5YE 4BY7E 1K83E 4MQ9E 1I3QF 2E2JF 4X6AE 4A3EF 1I6VE 3HKZH 1TWCE 3HOXF 2R7ZF 2B63E 2JA7F 3S16E 5C4XE 2E2HE 4A3IE 5IYDF 5M5XF 5IYBE 1Y1VF 3CQZF 5IP7F 5D4EE 4A3JF 3HOWE 1TWFF 5FJ8E 3HOVE 2JA8F 4BBSE 5M5WE 2WB1I 1YNNK 3S2DF 5C3EE 3H3VF 4KMUE 1EIKA 3M3YE 3HOUF 3GTOE 5IPLE 3EQLE 3S1NE 4BY1E 1R9TF 2CW0E 3S17E 5E17E 2E2IE 1I6HE 4C2ME 4AYBH 1SFOF 3GTMF 4G7HE 4A3DF 5IP9F 3GTJE 2NVYF 5M3FF 2NVQF 2JA6E 3I4MF 4A3KF 2R92F 4Y52E 4QIWK 4A3MF 3GTLF 3S2HF 4BXXE 1Y1WE 5TMFE 1YNJK 3GTKF 3S1RF 3S1QE 4XLNE 5D4DE 4C3IE 1WCMF 1I50E 3S14E 2B63F 5IYCE 5TMCE 2PPBE 4A3GE 4YFKE 5C4XF 4A3IF 4C3JE 2R93F 2NVXF 4C3HE 2YU9F 5IYBF 3H3VG 2NVTF 3HOWF 3M4OF 3FKIE 1ZYRE 4BBSF 5M5WF 3S15E 4KN4E 4LK1E 4MEXE 3GTPE 4LJZE 4QIWH 4XSZE 5C3EF 4A3BF 5FLME 4A93F 3HOZE 2O5JE 5C4JE 3RZOF 3GTQE 4Y7NE 3RZDE 1TWHF 4A3CE 1TWGF 2A68E 2E2IF 1I6HF 4G7ZE 4XSXE 1TWAE 2VUME 3S1ME 3GTJF 3WODE 5E18E 1I3QE 3H0GF 5M3MF 2KRXA 2E2JE 4OIQE 3PO3F 2Y0SI 3HOXE 2R7ZE 4BXXF 3DXJE 4BY7F 5M5YF 1K83F 4YFXE 2WB1H 2JA7E 2BE5E 4OIPE 5C44E 4A3LE 4X6AF 5IYDE 5M5XE 1TWCF 1I50F 3HOYE 4LK0E 3S14F 1Y1VE 3CQZE 4JK1E 5IP7E 4A3JE 4A3GF 1TWFE 3PO2E 3S16F 2E2HF 4C3JF 3S2DE 3HKZK 3I4NE 1HQME 3FKIF 5FJ8F 3HOVF 3HOUE 4ZH4E 4Q4ZE 2JA5E 1SMYE 3K7AE 1IW7E 3GTPF 4YFNE 3GTGE 2A6HE 5FLMF 1SFOE 4MEYE 3GTME 4KN7E 3GTOF 3M3YF 5IP9E 5M3FE 2NVQE 3GTQF 5BYHE 3S1NF 4BY1F 2PMZK 4OIOE 3S17F 2R92E 4A3ME 4C2MF 3S2HE 4BBRE 4A3FE 2O5IE 2JA6F 4OIRE 3S1RE 4Y52F 3GTKE 2WAQK 4A3EE 1WCME 1Y1WF 4AYBK 3S1QF 4A3LF 5C44F 4C3IF 2A69E 2R93E 2NVXE 2YU9E 3HOYF 4YG2E 5IYCF 3M4OE 2NVTE 3PO2F 4LLGE 4XLPE 2JA8E 2PMZH 4C3HF 3I4NF 4A3BE
chains in the Genus database with same CATH topology
3S15F 2JA5F 4Q5SE 3K7AF 3GTGF 4OINE 2A6EE 3HOZF 5C4JF 4GZYE 4Y7NF 3RZDF 4A3CF 3S1MF 5D4CE 2VUMF 4G7OE 1TWAF 4BBRF 1QKLA 4A3FF 4MQ9E 1I3QF 2E2JF 4A3EF 1I6VE 3HOXF 2R7ZF 2JA7F 5IYDF 5M5XF 1Y1VF 3CQZF 5IP7F 5D4EE 4A3JF 1TWFF 2JA8F 2WB1I 1YNNK 3S2DF 4KMUE 3HOUF 5IPLE 3EQLE 1R9TF 2CW0E 5E17E 1SFOF 3GTMF 4A3DF 4G7HE 5IP9F 5M3FF 2NVYF 2NVQF 3I4MF 4A3KF 2R92F 4QIWK 4A3MF 3GTLF 3S2HF 5TMFE 1YNJK 3GTKF 3S1RF 4XLNE 5D4DE 1WCMF 2B63F 5TMCE 2PPBE 4YFKE 5C4XF 4A3IF 2R93F 2NVXF 2YU9F 5IYBF 3H3VG 2NVTF 3HOWF 3M4OF 4BBSF 1ZYRE 5M5WF 4KN4E 4LK1E 4MEXE 4LJZE 5C3EF 4XSZE 4A3BF 4A93F 2O5JE 3RZOF 1TWHF 1TWGF 2A68E 2E2IF 1I6HF 4G7ZE 4XSXE 3GTJF 3WODE 5E18E 5M3MF 3H0GF 2KRXA 4OIQE 3PO3F 2Y0SI 4BXXF 3DXJE 4BY7F 5M5YF 1K83F 4YFXE 2BE5E 4OIPE 4X6AF 1TWCF 1I50F 4LK0E 3S14F 4JK1E 4A3GF 3S16F 2E2HF 4C3JF 3HKZK 1HQME 3FKIF 5FJ8F 3HOVF 4ZH4E 4Q4ZE 1SMYE 3GTPF 1IW7E 4YFNE 2A6HE 5FLMF 3M3YF 4MEYE 4KN7E 3GTOF 3GTQF 5BYHE 3S1NF 4BY1F 2PMZK 4OIOE 3S17F 4C2MF 2O5IE 2JA6F 4OIRE 4Y52F 2WAQK 1Y1WF 4AYBK 3S1QF 4A3LF 5C44F 4C3IF 2A69E 3HOYF 4YG2E 5IYCF 3PO2F 4LLGE 4XLPE 4C3HF 3I4NF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S15 F;  2JA5 F;  4Q5S E;  3K7A F;  3GTG F;  4OIN E;  2A6E E;  3HOZ F;  5C4J F;  4GZY E;  4Y7N F;  3RZD F;  4A3C F;  3S1M F;  5D4C E;  2VUM F;  4G7O E;  1TWA F;  4BBR F;  1QKL A;  4A3F F;  4MQ9 E;  1I3Q F;  2E2J F;  4A3E F;  1I6V E;  3HOX F;  2R7Z F;  2JA7 F;  5IYD F;  5M5X F;  1Y1V F;  3CQZ F;  5IP7 F;  5D4E E;  4A3J F;  1TWF F;  2JA8 F;  2WB1 I;  1YNN K;  3S2D F;  4KMU E;  3HOU F;  5IPL E;  3EQL E;  1R9T F;  2CW0 E;  5E17 E;  1SFO F;  3GTM F;  4A3D F;  4G7H E;  5IP9 F;  5M3F F;  2NVY F;  2NVQ F;  3I4M F;  4A3K F;  2R92 F;  4A3M F;  3GTL F;  3S2H F;  5TMF E;  1YNJ K;  3GTK F;  3S1R F;  4XLN E;  5D4D E;  1WCM F;  2B63 F;  5TMC E;  2PPB E;  4YFK E;  5C4X F;  4A3I F;  2R93 F;  2NVX F;  2YU9 F;  5IYB F;  3H3V G;  2NVT F;  3HOW F;  3M4O F;  4BBS F;  1ZYR E;  5M5W F;  4KN4 E;  4LK1 E;  4MEX E;  4LJZ E;  5C3E F;  4XSZ E;  4A3B F;  4A93 F;  2O5J E;  3RZO F;  1TWH F;  1TWG F;  2A68 E;  2E2I F;  1I6H F;  4G7Z E;  4XSX E;  3GTJ F;  3WOD E;  5E18 E;  5M3M F;  3H0G F;  4OIQ E;  3PO3 F;  2Y0S I;  4BXX F;  3DXJ E;  4BY7 F;  5M5Y F;  1K83 F;  4YFX E;  2BE5 E;  4OIP E;  4X6A F;  1TWC F;  1I50 F;  4LK0 E;  3S14 F;  4JK1 E;  4A3G F;  3S16 F;  2E2H F;  4C3J F;  3HKZ K;  1HQM E;  3FKI F;  5FJ8 F;  3HOV F;  4ZH4 E;  4Q4Z E;  1SMY E;  3GTP F;  1IW7 E;  4YFN E;  2A6H E;  5FLM F;  3M3Y F;  4MEY E;  4KN7 E;  3GTO F;  3GTQ F;  5BYH E;  3S1N F;  4BY1 F;  2PMZ K;  4OIO E;  3S17 F;  4C2M F;  2O5I E;  2JA6 F;  4OIR E;  4Y52 F;  2WAQ K;  1Y1W F;  4AYB K;  3S1Q F;  4A3L F;  5C44 F;  4C3I F;  2A69 E;  3HOY F;  4YG2 E;  5IYC F;  3PO2 F;  4LLG E;  4XLP E;  4C3H F;  3I4N F; 
#chains in the Genus database with same CATH topology
 4A93 E;  3S15 F;  2JA5 F;  4Q5S E;  3K7A F;  3RZO E;  2WAQ H;  1TWH E;  2Y0S H;  3GTG F;  1R9T E;  1TWG E;  4OIN E;  2A6E E;  4A3D E;  3HOZ F;  5C4J F;  4GZY E;  2NVY E;  4Y7N F;  3RZD F;  3I4M E;  5M3M E;  3H0G E;  4A3K E;  4A3C F;  3S1M F;  1DZF A;  5D4C E;  2VUM F;  3GTL E;  3PO3 E;  1TWA F;  4BBR F;  4G7O E;  1QKL A;  4A3F F;  5M5Y E;  4BY7 E;  1K83 E;  4MQ9 E;  1I3Q F;  2E2J F;  4X6A E;  4A3E F;  1I6V E;  3HKZ H;  1TWC E;  3HOX F;  2R7Z F;  2B63 E;  2JA7 F;  3S16 E;  5C4X E;  2E2H E;  4A3I E;  5IYD F;  5M5X F;  5IYB E;  1Y1V F;  3CQZ F;  5IP7 F;  5D4E E;  4A3J F;  3HOW E;  1TWF F;  5FJ8 E;  3HOV E;  2JA8 F;  4BBS E;  5M5W E;  2WB1 I;  1YNN K;  3S2D F;  5C3E E;  3H3V F;  4KMU E;  1EIK A;  3M3Y E;  3HOU F;  3GTO E;  5IPL E;  3EQL E;  3S1N E;  4BY1 E;  1R9T F;  2CW0 E;  3S17 E;  5E17 E;  2E2I E;  1I6H E;  4C2M E;  4AYB H;  1SFO F;  3GTM F;  4G7H E;  4A3D F;  5IP9 F;  3GTJ E;  2NVY F;  5M3F F;  2NVQ F;  2JA6 E;  3I4M F;  4A3K F;  2R92 F;  4Y52 E;  4QIW K;  4A3M F;  3GTL F;  3S2H F;  4BXX E;  1Y1W E;  5TMF E;  1YNJ K;  3GTK F;  3S1R F;  3S1Q E;  4XLN E;  5D4D E;  4C3I E;  1WCM F;  1I50 E;  3S14 E;  2B63 F;  5IYC E;  5TMC E;  2PPB E;  4A3G E;  4YFK E;  5C4X F;  4A3I F;  4C3J E;  2R93 F;  2NVX F;  4C3H E;  2YU9 F;  5IYB F;  3H3V G;  2NVT F;  3HOW F;  3M4O F;  3FKI E;  1ZYR E;  4BBS F;  5M5W F;  3S15 E;  4KN4 E;  4LK1 E;  4MEX E;  3GTP E;  4LJZ E;  4QIW H;  4XSZ E;  5C3E F;  4A3B F;  5FLM E;  4A93 F;  3HOZ E;  2O5J E;  5C4J E;  3RZO F;  3GTQ E;  4Y7N E;  3RZD E;  1TWH F;  4A3C E;  1TWG F;  2A68 E;  2E2I F;  1I6H F;  4G7Z E;  4XSX E;  1TWA E;  2VUM E;  3S1M E;  3GTJ F;  3WOD E;  5E18 E;  1I3Q E;  3H0G F;  5M3M F;  2KRX A;  2E2J E;  4OIQ E;  3PO3 F;  2Y0S I;  3HOX E;  2R7Z E;  4BXX F;  3DXJ E;  4BY7 F;  5M5Y F;  1K83 F;  4YFX E;  2WB1 H;  2JA7 E;  2BE5 E;  4OIP E;  5C44 E;  4A3L E;  4X6A F;  5IYD E;  5M5X E;  1TWC F;  1I50 F;  3HOY E;  4LK0 E;  3S14 F;  1Y1V E;  3CQZ E;  4JK1 E;  5IP7 E;  4A3J E;  4A3G F;  1TWF E;  3PO2 E;  3S16 F;  2E2H F;  4C3J F;  3S2D E;  3HKZ K;  3I4N E;  1HQM E;  3FKI F;  5FJ8 F;  3HOV F;  3HOU E;  4ZH4 E;  4Q4Z E;  2JA5 E;  1SMY E;  3K7A E;  1IW7 E;  3GTP F;  4YFN E;  3GTG E;  2A6H E;  5FLM F;  1SFO E;  4MEY E;  3GTM E;  4KN7 E;  3GTO F;  3M3Y F;  5IP9 E;  5M3F E;  2NVQ E;  3GTQ F;  5BYH E;  3S1N F;  4BY1 F;  2PMZ K;  4OIO E;  3S17 F;  2R92 E;  4A3M E;  4C2M F;  3S2H E;  4BBR E;  4A3F E;  2O5I E;  2JA6 F;  4OIR E;  3S1R E;  4Y52 F;  3GTK E;  2WAQ K;  4A3E E;  1WCM E;  1Y1W F;  4AYB K;  3S1Q F;  4A3L F;  5C44 F;  4C3I F;  2A69 E;  2R93 E;  2NVX E;  2YU9 E;  3HOY F;  4YG2 E;  5IYC F;  3M4O E;  2NVT E;  3PO2 F;  4LLG E;  4XLP E;  2JA8 E;  2PMZ H;  4C3H F;  3I4N F;  4A3B E; 
#chains in the Genus database with same CATH homology
 3S15 F;  2JA5 F;  4Q5S E;  3K7A F;  3GTG F;  4OIN E;  2A6E E;  3HOZ F;  5C4J F;  4GZY E;  4Y7N F;  3RZD F;  4A3C F;  3S1M F;  5D4C E;  2VUM F;  4G7O E;  1TWA F;  4BBR F;  1QKL A;  4A3F F;  4MQ9 E;  1I3Q F;  2E2J F;  4A3E F;  1I6V E;  3HOX F;  2R7Z F;  2JA7 F;  5IYD F;  5M5X F;  1Y1V F;  3CQZ F;  5IP7 F;  5D4E E;  4A3J F;  1TWF F;  2JA8 F;  2WB1 I;  1YNN K;  3S2D F;  4KMU E;  3HOU F;  5IPL E;  3EQL E;  1R9T F;  2CW0 E;  5E17 E;  1SFO F;  3GTM F;  4A3D F;  4G7H E;  5IP9 F;  5M3F F;  2NVY F;  2NVQ F;  3I4M F;  4A3K F;  2R92 F;  4QIW K;  4A3M F;  3GTL F;  3S2H F;  5TMF E;  1YNJ K;  3GTK F;  3S1R F;  4XLN E;  5D4D E;  1WCM F;  2B63 F;  5TMC E;  2PPB E;  4YFK E;  5C4X F;  4A3I F;  2R93 F;  2NVX F;  2YU9 F;  5IYB F;  3H3V G;  2NVT F;  3HOW F;  3M4O F;  4BBS F;  1ZYR E;  5M5W F;  4KN4 E;  4LK1 E;  4MEX E;  4LJZ E;  5C3E F;  4XSZ E;  4A3B F;  4A93 F;  2O5J E;  3RZO F;  1TWH F;  1TWG F;  2A68 E;  2E2I F;  1I6H F;  4G7Z E;  4XSX E;  3GTJ F;  3WOD E;  5E18 E;  5M3M F;  3H0G F;  2KRX A;  4OIQ E;  3PO3 F;  2Y0S I;  4BXX F;  3DXJ E;  4BY7 F;  5M5Y F;  1K83 F;  4YFX E;  2BE5 E;  4OIP E;  4X6A F;  1TWC F;  1I50 F;  4LK0 E;  3S14 F;  4JK1 E;  4A3G F;  3S16 F;  2E2H F;  4C3J F;  3HKZ K;  1HQM E;  3FKI F;  5FJ8 F;  3HOV F;  4ZH4 E;  4Q4Z E;  1SMY E;  3GTP F;  1IW7 E;  4YFN E;  2A6H E;  5FLM F;  3M3Y F;  4MEY E;  4KN7 E;  3GTO F;  3GTQ F;  5BYH E;  3S1N F;  4BY1 F;  2PMZ K;  4OIO E;  3S17 F;  4C2M F;  2O5I E;  2JA6 F;  4OIR E;  4Y52 F;  2WAQ K;  1Y1W F;  4AYB K;  3S1Q F;  4A3L F;  5C44 F;  4C3I F;  2A69 E;  3HOY F;  4YG2 E;  5IYC F;  3PO2 F;  4LLG E;  4XLP E;  4C3H F;  3I4N F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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