1WCMF

Complete 12-subunit rna polymerase ii at 3.8 angstrom
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Complete RNA Polymerase II and its Subcomplex,Rpb4/7
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 23
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2004-11-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1wcmF00
2JA8F 5M3MF 4KN4E 2R93F 1TWGF 2A68E 3S1NF 1TWHF 5IYBF 5IYCF 5TMFE 1ZYRE 3M4OF 3S1QF 3M3YF 4XLPE 5M3FF 1R9TF 3HOWF 1YNJK 1SMYE 1TWCF 5IPLE 3H0GF 3HOYF 2E2HF 2PMZK 4YG2E 4AYBK 4C3IF 1TWFF 5M5YF 4A3DF 5D4EE 4X6AF 4A93F 4A3FF 1IW7E 4BY7F 5M5XF 3S14F 2VUMF 4A3JF 1Y1VF 4G7HE 4A3CF 5E17E 4XSXE 1I3QF 4A3GF 1WCMF 2E2IF 2JA7F 4BXXF 3S2DF 3S1RF 3S17F 2NVYF 4BY1F 4YFKE 4A3BF 4OIOE 1K83F 4XSZE 4Q5SE 2YU9F 5D4DE 3CQZF 4OIQE 1Y1WF 2O5JE 3HOUF 5IYDF 2CW0E 4LK1E 3WODE 4GZYE 3GTKF 3HOXF 2A6EE 2A69E 3S1MF 5C3EF 3S16F 1HQME 4A3IF 2JA6F 3HKZK 4MEYE 5BYHE 5FJ8F 3RZOF 3RZDF 2BE5E 1I6HF 2PPBE 2O5IE 3GTGF 5FLMF 4LK0E 2JA5F 2NVXF 1YNNK 2NVQF 4YFXE 5C4JF 3I4MF 5TMCE 2Y0SI 4KMUE 4BBRF 4Y7NF 5M5WF 1SFOF 1QKLA 3S2HF 4BBSF 2B63F 5IP9F 5D4CE 1I6VE 5C4XF 1I50F 4Y52F 2NVTF 3GTOF 2R7ZF 5C44F 4A3MF 3FKIF 2R92F 4A3KF 4KN7E 4ZH4E 4LJZE 2WAQK 4XLNE 1TWAF 3GTJF 4MEXE 4C3JF 4OIPE 5IP7F 3K7AF 4YFNE 4Q4ZE 3I4NF 2A6HE 4MQ9E 3GTMF 3HOVF 3GTPF 3PO3F 4OINE 4LLGE 4G7ZE 3GTQF 4JK1E 3PO2F 3EQLE 2E2JF 4C2MF 3S15F 3H3VG 4A3EF 4OIRE 4G7OE 3HOZF 4A3LF 3GTLF 2WB1I 3DXJE 5E18E 4C3HF
chains in the Genus database with same CATH superfamily
2WAQH 2JA8F 5M3MF 1TWAE 4KN4E 3GTJE 2R93F 4C3JE 1TWGF 5IP7E 2A68E 3K7AE 3S1NF 1TWHF 5IYBF 2WB1H 5IYCF 5IYCE 5TMFE 1ZYRE 3M4OF 3M4OE 3I4NE 3S1QF 3M3YF 4XLPE 5M3FF 1R9TF 3GTME 3HOWF 1YNJK 3HOVE 3GTPE 3PO3E 1SMYE 1TWCF 5IPLE 3H0GF 3HOYF 2E2HF 2PMZK 4YG2E 4AYBK 4C3IF 1TWFF 3GTQE 2PMZH 5M5YF 4A3DF 3PO2E 4A3DE 5D4EE 2E2JE 4C2ME 3S15E 4X6AF 4A93F 4A3EE 3HOZE 4A3LE 4A3FF 1IW7E 4BY7F 5M5XF 5M5XE 3GTLE 3S14F 2VUMF 4A3JF 1Y1VF 4G7HE 4A3CF 5E17E 4XSXE 4C3HE 1I3QF 4A3GF 1WCMF 2E2IF 2JA7F 5M3ME 2JA8E 4BXXF 3S2DF 3S2DE 1DZFA 2R93E 1TWGE 3S1RF 3S17F 2NVYF 4BY1F 4YFKE 4A3BF 4OIOE 1K83F 3S1NE 1TWHE 4XSZE 5IYBE 4Q5SE 2YU9F 5D4DE 3CQZF 3S1QE 3M3YE 4OIQE 1Y1WF 5M3FE 3HOWE 1R9TE 2O5JE 3HOUF 5IYDF 2CW0E 1TWCE 4LK1E 3WODE 3H0GE 3GTKF 2KRXA 3HOYE 2E2HE 4GZYE 3HOXF 4C3IE 2A6EE 2A69E 3S1MF 1TWFE 5C3EF 4AYBH 3S16F 5M5YE 1HQME 4A3IF 2JA6F 4X6AE 3HKZK 4A93E 4MEYE 3HKZH 4A3FE 5BYHE 4BY7E 3S14E 5FJ8F 2VUME 3RZOF 4A3JE 1Y1VE 4A3CE 3RZDF 1I3QE 2BE5E 2PPBE 1I6HF 1WCME 2E2IE 2JA7E 4BXXE 3H3VF 4A3GE 2O5IE 3GTGF 5FLMF 4LK0E 2JA5F 2NVXF 1YNNK 3S1RE 4YFXE 2NVYE 5C4JF 4BY1E 3I4MF 3S17E 1K83E 5TMCE 4A3BE 2Y0SI 4KMUE 4BBRF 4Y7NF 5M5WF 1SFOF 1QKLA 3S2HF 3S2HE 2B63F 2YU9E 4BBSF 3CQZE 5IP9F 5D4CE 1I6VE 5C4XF 1Y1WE 2NVQF 1I50F 4Y52F 2NVTF 3GTOF 5IYDE 3HOUE 2R7ZF 5C44F 4A3MF 3FKIF 3GTKE 3HOXE 2Y0SH 4A3KF 2R92F 4KN7E 3S1ME 4ZH4E 4LJZE 5C3EE 3S16E 2WAQK 4A3IE 2JA6E 4XLNE 1TWAF 3GTJF 4MEXE 4C3JF 4OIPE 5IP7F 3K7AF 5FJ8E 3RZOE 4YFNE 3RZDE 1EIKA 1I6HE 4Q4ZE 3I4NF 2A6HE 4QIWK 4MQ9E 3GTGE 5FLME 2JA5E 2NVQE 2NVXE 4QIWH 3GTMF 3HOVF 5C4JE 3I4ME 3GTPF 3PO3F 4BBRE 5M5WE 4Y7NE 1SFOE 4OINE 4LLGE 4BBSE 4G7ZE 2B63E 5IP9E 5C4XE 3GTQF 4JK1E 1I50E 2NVTE 3GTOE 3EQLE 3PO2F 4Y52E 2E2JF 4C2MF 2R7ZE 5C44E 4A3ME 4A3EF 4OIRE 3FKIE 3H3VG 3HOZF 3S15F 4A3LF 4G7OE 3GTLF 2R92E 2WB1I 4A3KE 3DXJE 5E18E 4C3HF
chains in the Genus database with same CATH topology
2JA8F 5M3MF 4KN4E 2R93F 1TWGF 2A68E 3S1NF 1TWHF 5IYBF 5IYCF 5TMFE 1ZYRE 3M4OF 3S1QF 3M3YF 4XLPE 5M3FF 1R9TF 3HOWF 1YNJK 1SMYE 1TWCF 5IPLE 3H0GF 3HOYF 2E2HF 2PMZK 4YG2E 4AYBK 4C3IF 1TWFF 5M5YF 4A3DF 5D4EE 4X6AF 4A93F 4A3FF 1IW7E 4BY7F 5M5XF 3S14F 2VUMF 4A3JF 1Y1VF 4G7HE 4A3CF 5E17E 4XSXE 1I3QF 4A3GF 1WCMF 2E2IF 2JA7F 4BXXF 3S2DF 3S1RF 3S17F 2NVYF 4BY1F 4YFKE 4A3BF 4OIOE 1K83F 4XSZE 4Q5SE 2YU9F 5D4DE 3CQZF 4OIQE 1Y1WF 2O5JE 3HOUF 5IYDF 2CW0E 4LK1E 3WODE 4GZYE 3GTKF 2KRXA 3HOXF 2A6EE 2A69E 3S1MF 5C3EF 3S16F 1HQME 4A3IF 2JA6F 3HKZK 4MEYE 5BYHE 5FJ8F 3RZOF 3RZDF 2BE5E 1I6HF 2PPBE 2O5IE 3GTGF 5FLMF 4LK0E 2JA5F 2NVXF 1YNNK 2NVQF 4YFXE 5C4JF 3I4MF 5TMCE 2Y0SI 4KMUE 4BBRF 4Y7NF 5M5WF 1SFOF 1QKLA 3S2HF 4BBSF 2B63F 5IP9F 5D4CE 1I6VE 5C4XF 1I50F 4Y52F 2NVTF 3GTOF 2R7ZF 5C44F 4A3MF 3FKIF 2R92F 4A3KF 4KN7E 4ZH4E 4LJZE 2WAQK 4XLNE 1TWAF 3GTJF 4MEXE 4C3JF 4OIPE 5IP7F 3K7AF 4YFNE 4Q4ZE 3I4NF 2A6HE 4QIWK 4MQ9E 3GTMF 3HOVF 3GTPF 3PO3F 4OINE 4LLGE 4G7ZE 3GTQF 4JK1E 3PO2F 3EQLE 2E2JF 4C2MF 3S15F 3H3VG 4A3EF 4OIRE 4G7OE 3HOZF 4A3LF 3GTLF 2WB1I 3DXJE 5E18E 4C3HF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JA8 F;  5M3M F;  4KN4 E;  2R93 F;  1TWG F;  2A68 E;  3S1N F;  1TWH F;  5IYB F;  5IYC F;  5TMF E;  1ZYR E;  3M4O F;  3S1Q F;  3M3Y F;  4XLP E;  5M3F F;  1R9T F;  3HOW F;  1YNJ K;  1SMY E;  1TWC F;  5IPL E;  3H0G F;  3HOY F;  2E2H F;  2PMZ K;  4YG2 E;  4AYB K;  4C3I F;  1TWF F;  5M5Y F;  4A3D F;  5D4E E;  4X6A F;  4A93 F;  4A3F F;  1IW7 E;  4BY7 F;  5M5X F;  3S14 F;  2VUM F;  4A3J F;  1Y1V F;  4G7H E;  4A3C F;  5E17 E;  4XSX E;  1I3Q F;  4A3G F;  1WCM F;  2E2I F;  2JA7 F;  4BXX F;  3S2D F;  3S1R F;  3S17 F;  2NVY F;  4BY1 F;  4YFK E;  4A3B F;  4OIO E;  1K83 F;  4XSZ E;  4Q5S E;  2YU9 F;  5D4D E;  3CQZ F;  4OIQ E;  1Y1W F;  2O5J E;  3HOU F;  5IYD F;  2CW0 E;  4LK1 E;  3WOD E;  4GZY E;  3GTK F;  3HOX F;  2A6E E;  2A69 E;  3S1M F;  5C3E F;  3S16 F;  1HQM E;  4A3I F;  2JA6 F;  3HKZ K;  4MEY E;  5BYH E;  5FJ8 F;  3RZO F;  3RZD F;  2BE5 E;  1I6H F;  2PPB E;  2O5I E;  3GTG F;  5FLM F;  4LK0 E;  2JA5 F;  2NVX F;  1YNN K;  2NVQ F;  4YFX E;  5C4J F;  3I4M F;  5TMC E;  2Y0S I;  4KMU E;  4BBR F;  4Y7N F;  5M5W F;  1SFO F;  1QKL A;  3S2H F;  4BBS F;  2B63 F;  5IP9 F;  5D4C E;  1I6V E;  5C4X F;  1I50 F;  4Y52 F;  2NVT F;  3GTO F;  2R7Z F;  5C44 F;  4A3M F;  3FKI F;  2R92 F;  4A3K F;  4KN7 E;  4ZH4 E;  4LJZ E;  2WAQ K;  4XLN E;  1TWA F;  3GTJ F;  4MEX E;  4C3J F;  4OIP E;  5IP7 F;  3K7A F;  4YFN E;  4Q4Z E;  3I4N F;  2A6H E;  4MQ9 E;  3GTM F;  3HOV F;  3GTP F;  3PO3 F;  4OIN E;  4LLG E;  4G7Z E;  3GTQ F;  4JK1 E;  3PO2 F;  3EQL E;  2E2J F;  4C2M F;  3S15 F;  3H3V G;  4A3E F;  4OIR E;  4G7O E;  3HOZ F;  4A3L F;  3GTL F;  2WB1 I;  3DXJ E;  5E18 E;  4C3H F; 
#chains in the Genus database with same CATH topology
 2WAQ H;  2JA8 F;  5M3M F;  1TWA E;  4KN4 E;  3GTJ E;  2R93 F;  4C3J E;  1TWG F;  5IP7 E;  2A68 E;  3K7A E;  3S1N F;  1TWH F;  5IYB F;  2WB1 H;  5IYC F;  5IYC E;  5TMF E;  1ZYR E;  3M4O F;  3M4O E;  3I4N E;  3S1Q F;  3M3Y F;  4XLP E;  5M3F F;  1R9T F;  3GTM E;  3HOW F;  1YNJ K;  3HOV E;  3GTP E;  3PO3 E;  1SMY E;  1TWC F;  5IPL E;  3H0G F;  3HOY F;  2E2H F;  2PMZ K;  4YG2 E;  4AYB K;  4C3I F;  1TWF F;  3GTQ E;  2PMZ H;  5M5Y F;  4A3D F;  3PO2 E;  4A3D E;  5D4E E;  2E2J E;  4C2M E;  3S15 E;  4X6A F;  4A93 F;  4A3E E;  3HOZ E;  4A3L E;  4A3F F;  1IW7 E;  4BY7 F;  5M5X F;  5M5X E;  3GTL E;  3S14 F;  2VUM F;  4A3J F;  1Y1V F;  4G7H E;  4A3C F;  5E17 E;  4XSX E;  4C3H E;  1I3Q F;  4A3G F;  1WCM F;  2E2I F;  2JA7 F;  5M3M E;  2JA8 E;  4BXX F;  3S2D F;  3S2D E;  1DZF A;  2R93 E;  1TWG E;  3S1R F;  3S17 F;  2NVY F;  4BY1 F;  4YFK E;  4A3B F;  4OIO E;  1K83 F;  3S1N E;  1TWH E;  4XSZ E;  5IYB E;  4Q5S E;  2YU9 F;  5D4D E;  3CQZ F;  3S1Q E;  3M3Y E;  4OIQ E;  1Y1W F;  5M3F E;  3HOW E;  1R9T E;  2O5J E;  3HOU F;  5IYD F;  2CW0 E;  1TWC E;  4LK1 E;  3WOD E;  3H0G E;  3GTK F;  2KRX A;  3HOY E;  2E2H E;  4GZY E;  3HOX F;  4C3I E;  2A6E E;  2A69 E;  3S1M F;  1TWF E;  5C3E F;  4AYB H;  3S16 F;  5M5Y E;  1HQM E;  4A3I F;  2JA6 F;  4X6A E;  3HKZ K;  4A93 E;  4MEY E;  3HKZ H;  4A3F E;  5BYH E;  4BY7 E;  3S14 E;  5FJ8 F;  2VUM E;  3RZO F;  4A3J E;  1Y1V E;  4A3C E;  3RZD F;  1I3Q E;  2BE5 E;  2PPB E;  1I6H F;  1WCM E;  2E2I E;  2JA7 E;  4BXX E;  3H3V F;  4A3G E;  2O5I E;  3GTG F;  5FLM F;  4LK0 E;  2JA5 F;  2NVX F;  1YNN K;  3S1R E;  4YFX E;  2NVY E;  5C4J F;  4BY1 E;  3I4M F;  3S17 E;  1K83 E;  5TMC E;  4A3B E;  2Y0S I;  4KMU E;  4BBR F;  4Y7N F;  5M5W F;  1SFO F;  1QKL A;  3S2H F;  3S2H E;  2B63 F;  2YU9 E;  4BBS F;  3CQZ E;  5IP9 F;  5D4C E;  1I6V E;  5C4X F;  1Y1W E;  2NVQ F;  1I50 F;  4Y52 F;  2NVT F;  3GTO F;  5IYD E;  3HOU E;  2R7Z F;  5C44 F;  4A3M F;  3FKI F;  3GTK E;  3HOX E;  2Y0S H;  4A3K F;  2R92 F;  4KN7 E;  3S1M E;  4ZH4 E;  4LJZ E;  5C3E E;  3S16 E;  2WAQ K;  4A3I E;  2JA6 E;  4XLN E;  1TWA F;  3GTJ F;  4MEX E;  4C3J F;  4OIP E;  5IP7 F;  3K7A F;  5FJ8 E;  3RZO E;  4YFN E;  3RZD E;  1EIK A;  1I6H E;  4Q4Z E;  3I4N F;  2A6H E;  4QIW K;  4MQ9 E;  3GTG E;  5FLM E;  2JA5 E;  2NVQ E;  2NVX E;  4QIW H;  3GTM F;  3HOV F;  5C4J E;  3I4M E;  3GTP F;  3PO3 F;  4BBR E;  5M5W E;  4Y7N E;  1SFO E;  4OIN E;  4LLG E;  4BBS E;  4G7Z E;  2B63 E;  5IP9 E;  5C4X E;  3GTQ F;  4JK1 E;  1I50 E;  2NVT E;  3GTO E;  3EQL E;  3PO2 F;  4Y52 E;  2E2J F;  4C2M F;  2R7Z E;  5C44 E;  4A3M E;  4A3E F;  4OIR E;  3FKI E;  3H3V G;  3HOZ F;  3S15 F;  4A3L F;  4G7O E;  3GTL F;  2R92 E;  2WB1 I;  4A3K E;  3DXJ E;  5E18 E;  4C3H F; 
#chains in the Genus database with same CATH homology
 2JA8 F;  5M3M F;  4KN4 E;  2R93 F;  1TWG F;  2A68 E;  3S1N F;  1TWH F;  5IYB F;  5IYC F;  5TMF E;  1ZYR E;  3M4O F;  3S1Q F;  3M3Y F;  4XLP E;  5M3F F;  1R9T F;  3HOW F;  1YNJ K;  1SMY E;  1TWC F;  5IPL E;  3H0G F;  3HOY F;  2E2H F;  2PMZ K;  4YG2 E;  4AYB K;  4C3I F;  1TWF F;  5M5Y F;  4A3D F;  5D4E E;  4X6A F;  4A93 F;  4A3F F;  1IW7 E;  4BY7 F;  5M5X F;  3S14 F;  2VUM F;  4A3J F;  1Y1V F;  4G7H E;  4A3C F;  5E17 E;  4XSX E;  1I3Q F;  4A3G F;  1WCM F;  2E2I F;  2JA7 F;  4BXX F;  3S2D F;  3S1R F;  3S17 F;  2NVY F;  4BY1 F;  4YFK E;  4A3B F;  4OIO E;  1K83 F;  4XSZ E;  4Q5S E;  2YU9 F;  5D4D E;  3CQZ F;  4OIQ E;  1Y1W F;  2O5J E;  3HOU F;  5IYD F;  2CW0 E;  4LK1 E;  3WOD E;  4GZY E;  3GTK F;  2KRX A;  3HOX F;  2A6E E;  2A69 E;  3S1M F;  5C3E F;  3S16 F;  1HQM E;  4A3I F;  2JA6 F;  3HKZ K;  4MEY E;  5BYH E;  5FJ8 F;  3RZO F;  3RZD F;  2BE5 E;  1I6H F;  2PPB E;  2O5I E;  3GTG F;  5FLM F;  4LK0 E;  2JA5 F;  2NVX F;  1YNN K;  2NVQ F;  4YFX E;  5C4J F;  3I4M F;  5TMC E;  2Y0S I;  4KMU E;  4BBR F;  4Y7N F;  5M5W F;  1SFO F;  1QKL A;  3S2H F;  4BBS F;  2B63 F;  5IP9 F;  5D4C E;  1I6V E;  5C4X F;  1I50 F;  4Y52 F;  2NVT F;  3GTO F;  2R7Z F;  5C44 F;  4A3M F;  3FKI F;  2R92 F;  4A3K F;  4KN7 E;  4ZH4 E;  4LJZ E;  2WAQ K;  4XLN E;  1TWA F;  3GTJ F;  4MEX E;  4C3J F;  4OIP E;  5IP7 F;  3K7A F;  4YFN E;  4Q4Z E;  3I4N F;  2A6H E;  4QIW K;  4MQ9 E;  3GTM F;  3HOV F;  3GTP F;  3PO3 F;  4OIN E;  4LLG E;  4G7Z E;  3GTQ F;  4JK1 E;  3PO2 F;  3EQL E;  2E2J F;  4C2M F;  3S15 F;  3H3V G;  4A3E F;  4OIR E;  4G7O E;  3HOZ F;  4A3L F;  3GTL F;  2WB1 I;  3DXJ E;  5E18 E;  4C3H F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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