1YNNK

Taq rna polymerase-rifampicin complex
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
95
structure length
95
Chain Sequence
MAEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHRFKNTVLEPEERPKMRTLEGLYDDPNAVTWAMKELLTGRLFFGENLVPEDRLQKEMERLYPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-directed RNA polymerase alpha chain
total genus 19
structure length 95
sequence length 95
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2005-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1ynnK00
3FKIF 3S15F 1SMYE 1I6VE 4A3KF 1I6HF 3H0GF 4A3IF 4MEYE 2PMZK 3S1NF 4A3GF 5TMFE 2O5IE 2JA5F 3RZOF 3HOYF 5D4CE 5C44F 3S1RF 3GTLF 4A3DF 4A3BF 4BBRF 3K7AF 3H3VG 3GTOF 3HOUF 1TWHF 4KN4E 3S17F 1TWFF 3HKZK 4Q4ZE 1YNNK 4C2MF 4A3EF 4C3IF 4BY1F 2E2HF 5M5WF 4XSXE 3PO2F 3DXJE 4OIPE 4OIRE 5C4JF 5M5YF 5M3MF 5FJ8F 3PO3F 2A68E 3GTKF 3S1MF 3GTJF 4BXXF 5FLMF 1WCMF 4YFKE 5D4EE 2A69E 4Y52F 4XLPE 4OIOE 3S2HF 4A3CF 5IYDF 3EQLE 3GTGF 4XSZE 4BBSF 4A3JF 4X6AF 4XLNE 1ZYRE 4YFXE 5IPLE 4YG2E 5IP7F 4GZYE 4KN7E 1I3QF 2JA8F 3S1QF 1QKLA 3GTMF 3S2DF 5IP9F 5IYBF 4LK1E 2R93F 5M5XF 2JA6F 5D4DE 1IW7E 2E2JF 4A3LF 4MQ9E 4LJZE 1YNJK 1TWCF 5M3FF 4YFNE 3I4MF 1HQME 4G7OE 4MEXE 2O5JE 2R7ZF 3GTQF 5E18E 5C3EF 2A6EE 2YU9F 4A93F 4C3JF 2NVTF 3M4OF 5E17E 3HOVF 1TWAF 4BY7F 4Q5SE 3WODE 3RZDF 2B63F 4G7HE 1R9TF 2CW0E 5BYHE 1Y1VF 3HOWF 2NVYF 2BE5E 1Y1WF 2NVXF 3HOXF 2A6HE 4LK0E 4A3FF 4G7ZE 3S14F 2R92F 3M3YF 4LLGE 4JK1E 5C4XF 1I50F 5TMCE 3GTPF 3CQZF 4KMUE 3HOZF 2E2IF 3S16F 4C3HF 2VUMF 4A3MF 1K83F 1TWGF 4OIQE 4OINE 2Y0SI 4Y7NF 2WAQK 2WB1I 2JA7F 5IYCF 2PPBE 2NVQF 1SFOF 4ZH4E 4AYBK 3I4NF
chains in the Genus database with same CATH superfamily
3FKIF 4C3IE 3S15F 1SMYE 1I6VE 4A3KF 2E2HE 5M5WE 4BY1E 3PO2E 1I6HF 3H0GF 4A3IF 4MEYE 2PMZK 5C4JE 5M5YE 3S1NF 5TMFE 5M3ME 3PO3E 4A3GF 2O5IE 2JA5F 3GTKE 3S1ME 3RZOF 5D4CE 5C44F 3GTJE 3S1RF 3GTLF 3HOYF 5FLME 4BXXE 2Y0SH 4A3DF 4A3BF 4BBRF 2WB1H 1WCME 3K7AF 3GTOF 3H3VG 3HOUF 3I4ME 1TWHF 4KN4E 3S17F 4Y52E 1TWFF 3S2HE 4A3CE 3HKZK 4Q4ZE 1YNNK 4C2MF 5IYDE 4C3IF 4A3EF 3GTGE 4BY1F 2E2HF 5M5WF 4XSXE 3PO2F 3DXJE 4OIPE 4A3JE 5C4JF 5M5YF 4OIRE 5M3MF 5FJ8F 3PO3F 2A68E 4BBSE 5IP7E 3GTKF 3S1MF 1I3QE 2JA8E 3GTJF 4BXXF 5FLMF 3S1QE 3GTME 1WCMF 3S2DE 5IP9E 4YFKE 5IYBE 4QIWH 5D4EE 2A69E 4Y52F 4XLPE 4OIOE 5M5XE 2JA6E 3I4NF 3S2HF 4A3CF 2R93E 2E2JE 5IYDF 4A3LE 3EQLE 3GTGF 4XSZE 4BBSF 4A3JF 1TWCE 4X6AF 2KRXA 3H3VF 4XLNE 4YFXE 1ZYRE 5IPLE 4YG2E 5M3FE 4AYBH 5IP7F 4GZYE 4KN7E 1I3QF 2JA8F 3S1QF 1QKLA 2R7ZE 3GTQE 3GTMF 3S2DF 5IP9F 5IYBF 2PMZH 4LK1E 5C3EE 2R93F 5M5XF 2JA6F 5D4DE 1IW7E 2E2JF 2YU9E 4A93E 4A3LF 4X6AE 4C3HE 4MQ9E 4C3JE 4LJZE 1YNJK 2NVTE 3M4OE 3HOVE 1TWAE 1TWCF 4Y7NE 5M3FF 4BY7E 4YFNE 3I4MF 1HQME 4G7OE 4MEXE 2O5JE 3RZDE 3GTQF 2B63E 2R7ZF 2WAQH 5E18E 1R9TE 5C3EF 2A6EE 1Y1VE 3HOWE 1EIKA 2YU9F 4A93F 2NVYE 4C3JF 4QIWK 1Y1WE 2NVTF 2NVXE 3M4OF 5E17E 3HOXE 3HOVF 1TWAF 3RZOE 4A3FE 4BY7F 3S1RE 4Q5SE 3S14E 4A3DE 2R92E 3M3YE 3WODE 5C4XE 1I50E 3RZDF 3GTPE 3CQZE 2B63F 1DZFA 3HOZE 4G7HE 2E2IE 3S16E 1R9TF 2CW0E 2VUME 4A3ME 5BYHE 1K83E 1TWGE 1Y1VF 3HOWF 2NVYF 2BE5E 1Y1WF 3HKZH 5FJ8E 2NVXF 2JA7E 3HOXF 2A6HE 4LK0E 5IYCE 2NVQE 4A3FF 4G7ZE 3S14F 1SFOE 2R92F 3M3YF 4LLGE 4JK1E 3FKIE 1I50F 5TMCE 4A3KE 3I4NE 3GTPF 3CQZF 3S15E 5C4XF 4KMUE 3HOZF 3H0GE 4A3IE 4C3HF 2E2IF 3S16F 3S1NE 1I6HE 2VUMF 4A3MF 4A3GE 1K83F 1TWGF 4OIQE 2JA5E 4OINE 3HOYE 2Y0SI 5C44E 4Y7NF 2WAQK 3GTLE 2WB1I 2JA7F 4A3BE 4BBRE 3K7AE 3GTOE 3HOUE 5IYCF 1TWHE 2PPBE 2NVQF 3S17E 1TWFE 1SFOF 4ZH4E 4AYBK 4C2ME 4A3EE
chains in the Genus database with same CATH topology
3FKIF 3S15F 1SMYE 1I6VE 4A3KF 1I6HF 3H0GF 4A3IF 4MEYE 2PMZK 3S1NF 4A3GF 5TMFE 2O5IE 2JA5F 3RZOF 3HOYF 5D4CE 5C44F 3S1RF 3GTLF 4A3DF 4A3BF 4BBRF 3K7AF 3H3VG 3GTOF 3HOUF 1TWHF 4KN4E 3S17F 1TWFF 3HKZK 4Q4ZE 1YNNK 4C2MF 4A3EF 4C3IF 4BY1F 2E2HF 5M5WF 4XSXE 3PO2F 3DXJE 4OIPE 4OIRE 5C4JF 5M5YF 5M3MF 5FJ8F 3PO3F 2A68E 3GTKF 3S1MF 3GTJF 4BXXF 5FLMF 1WCMF 4YFKE 5D4EE 2A69E 4Y52F 4XLPE 4OIOE 3S2HF 4A3CF 5IYDF 3EQLE 3GTGF 4XSZE 4BBSF 4A3JF 4X6AF 2KRXA 4XLNE 1ZYRE 4YFXE 5IPLE 4YG2E 5IP7F 4GZYE 4KN7E 1I3QF 2JA8F 3S1QF 1QKLA 3GTMF 3S2DF 5IP9F 5IYBF 4LK1E 2R93F 5M5XF 2JA6F 5D4DE 1IW7E 2E2JF 4A3LF 4MQ9E 4LJZE 1YNJK 1TWCF 5M3FF 4YFNE 3I4MF 1HQME 4G7OE 4MEXE 2O5JE 2R7ZF 3GTQF 5E18E 5C3EF 2A6EE 2YU9F 4A93F 4C3JF 4QIWK 2NVTF 3M4OF 5E17E 3HOVF 1TWAF 4BY7F 4Q5SE 3WODE 3RZDF 2B63F 4G7HE 1R9TF 2CW0E 5BYHE 1Y1VF 3HOWF 2NVYF 2BE5E 1Y1WF 2NVXF 3HOXF 2A6HE 4LK0E 4A3FF 4G7ZE 3S14F 2R92F 3M3YF 4LLGE 4JK1E 5C4XF 1I50F 5TMCE 3GTPF 3CQZF 4KMUE 3HOZF 2E2IF 3S16F 4C3HF 2VUMF 4A3MF 1K83F 1TWGF 4OIQE 4OINE 2Y0SI 4Y7NF 2WAQK 2WB1I 2JA7F 5IYCF 2PPBE 2NVQF 1SFOF 4ZH4E 4AYBK 3I4NF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FKI F;  3S15 F;  1SMY E;  1I6V E;  4A3K F;  1I6H F;  3H0G F;  4A3I F;  4MEY E;  2PMZ K;  3S1N F;  4A3G F;  5TMF E;  2O5I E;  2JA5 F;  3RZO F;  3HOY F;  5D4C E;  5C44 F;  3S1R F;  3GTL F;  4A3D F;  4A3B F;  4BBR F;  3K7A F;  3H3V G;  3GTO F;  3HOU F;  1TWH F;  4KN4 E;  3S17 F;  1TWF F;  3HKZ K;  4Q4Z E;  1YNN K;  4C2M F;  4A3E F;  4C3I F;  4BY1 F;  2E2H F;  5M5W F;  4XSX E;  3PO2 F;  3DXJ E;  4OIP E;  4OIR E;  5C4J F;  5M5Y F;  5M3M F;  5FJ8 F;  3PO3 F;  2A68 E;  3GTK F;  3S1M F;  3GTJ F;  4BXX F;  5FLM F;  1WCM F;  4YFK E;  5D4E E;  2A69 E;  4Y52 F;  4XLP E;  4OIO E;  3S2H F;  4A3C F;  5IYD F;  3EQL E;  3GTG F;  4XSZ E;  4BBS F;  4A3J F;  4X6A F;  4XLN E;  1ZYR E;  4YFX E;  5IPL E;  4YG2 E;  5IP7 F;  4GZY E;  4KN7 E;  1I3Q F;  2JA8 F;  3S1Q F;  1QKL A;  3GTM F;  3S2D F;  5IP9 F;  5IYB F;  4LK1 E;  2R93 F;  5M5X F;  2JA6 F;  5D4D E;  1IW7 E;  2E2J F;  4A3L F;  4MQ9 E;  4LJZ E;  1YNJ K;  1TWC F;  5M3F F;  4YFN E;  3I4M F;  1HQM E;  4G7O E;  4MEX E;  2O5J E;  2R7Z F;  3GTQ F;  5E18 E;  5C3E F;  2A6E E;  2YU9 F;  4A93 F;  4C3J F;  2NVT F;  3M4O F;  5E17 E;  3HOV F;  1TWA F;  4BY7 F;  4Q5S E;  3WOD E;  3RZD F;  2B63 F;  4G7H E;  1R9T F;  2CW0 E;  5BYH E;  1Y1V F;  3HOW F;  2NVY F;  2BE5 E;  1Y1W F;  2NVX F;  3HOX F;  2A6H E;  4LK0 E;  4A3F F;  4G7Z E;  3S14 F;  2R92 F;  3M3Y F;  4LLG E;  4JK1 E;  5C4X F;  1I50 F;  5TMC E;  3GTP F;  3CQZ F;  4KMU E;  3HOZ F;  2E2I F;  3S16 F;  4C3H F;  2VUM F;  4A3M F;  1K83 F;  1TWG F;  4OIQ E;  4OIN E;  2Y0S I;  4Y7N F;  2WAQ K;  2WB1 I;  2JA7 F;  5IYC F;  2PPB E;  2NVQ F;  1SFO F;  4ZH4 E;  4AYB K;  3I4N F; 
#chains in the Genus database with same CATH topology
 3FKI F;  4C3I E;  3S15 F;  1SMY E;  1I6V E;  4A3K F;  2E2H E;  5M5W E;  4BY1 E;  3PO2 E;  1I6H F;  3H0G F;  4A3I F;  4MEY E;  2PMZ K;  5C4J E;  5M5Y E;  3S1N F;  5TMF E;  5M3M E;  3PO3 E;  4A3G F;  2O5I E;  2JA5 F;  3GTK E;  3S1M E;  3RZO F;  5D4C E;  5C44 F;  3GTJ E;  3S1R F;  3GTL F;  3HOY F;  5FLM E;  4BXX E;  2Y0S H;  4A3D F;  4A3B F;  4BBR F;  2WB1 H;  1WCM E;  3K7A F;  3GTO F;  3H3V G;  3HOU F;  3I4M E;  1TWH F;  4KN4 E;  3S17 F;  4Y52 E;  1TWF F;  3S2H E;  4A3C E;  3HKZ K;  4Q4Z E;  1YNN K;  4C2M F;  5IYD E;  4C3I F;  4A3E F;  3GTG E;  4BY1 F;  2E2H F;  5M5W F;  4XSX E;  3PO2 F;  3DXJ E;  4OIP E;  4A3J E;  5C4J F;  5M5Y F;  4OIR E;  5M3M F;  5FJ8 F;  3PO3 F;  2A68 E;  4BBS E;  5IP7 E;  3GTK F;  3S1M F;  1I3Q E;  2JA8 E;  3GTJ F;  4BXX F;  5FLM F;  3S1Q E;  3GTM E;  1WCM F;  3S2D E;  5IP9 E;  4YFK E;  5IYB E;  4QIW H;  5D4E E;  2A69 E;  4Y52 F;  4XLP E;  4OIO E;  5M5X E;  2JA6 E;  3I4N F;  3S2H F;  4A3C F;  2R93 E;  2E2J E;  5IYD F;  4A3L E;  3EQL E;  3GTG F;  4XSZ E;  4BBS F;  4A3J F;  1TWC E;  4X6A F;  2KRX A;  3H3V F;  4XLN E;  4YFX E;  1ZYR E;  5IPL E;  4YG2 E;  5M3F E;  4AYB H;  5IP7 F;  4GZY E;  4KN7 E;  1I3Q F;  2JA8 F;  3S1Q F;  1QKL A;  2R7Z E;  3GTQ E;  3GTM F;  3S2D F;  5IP9 F;  5IYB F;  2PMZ H;  4LK1 E;  5C3E E;  2R93 F;  5M5X F;  2JA6 F;  5D4D E;  1IW7 E;  2E2J F;  2YU9 E;  4A93 E;  4A3L F;  4X6A E;  4C3H E;  4MQ9 E;  4C3J E;  4LJZ E;  1YNJ K;  2NVT E;  3M4O E;  3HOV E;  1TWA E;  1TWC F;  4Y7N E;  5M3F F;  4BY7 E;  4YFN E;  3I4M F;  1HQM E;  4G7O E;  4MEX E;  2O5J E;  3RZD E;  3GTQ F;  2B63 E;  2R7Z F;  2WAQ H;  5E18 E;  1R9T E;  5C3E F;  2A6E E;  1Y1V E;  3HOW E;  1EIK A;  2YU9 F;  4A93 F;  2NVY E;  4C3J F;  4QIW K;  1Y1W E;  2NVT F;  2NVX E;  3M4O F;  5E17 E;  3HOX E;  3HOV F;  1TWA F;  3RZO E;  4A3F E;  4BY7 F;  3S1R E;  4Q5S E;  3S14 E;  4A3D E;  2R92 E;  3M3Y E;  3WOD E;  5C4X E;  1I50 E;  3RZD F;  3GTP E;  3CQZ E;  2B63 F;  1DZF A;  3HOZ E;  4G7H E;  2E2I E;  3S16 E;  1R9T F;  2CW0 E;  2VUM E;  4A3M E;  5BYH E;  1K83 E;  1TWG E;  1Y1V F;  3HOW F;  2NVY F;  2BE5 E;  1Y1W F;  3HKZ H;  5FJ8 E;  2NVX F;  2JA7 E;  3HOX F;  2A6H E;  4LK0 E;  5IYC E;  2NVQ E;  4A3F F;  4G7Z E;  3S14 F;  1SFO E;  2R92 F;  3M3Y F;  4LLG E;  4JK1 E;  3FKI E;  1I50 F;  5TMC E;  4A3K E;  3I4N E;  3GTP F;  3CQZ F;  3S15 E;  5C4X F;  4KMU E;  3HOZ F;  3H0G E;  4A3I E;  4C3H F;  2E2I F;  3S16 F;  3S1N E;  1I6H E;  2VUM F;  4A3M F;  4A3G E;  1K83 F;  1TWG F;  4OIQ E;  2JA5 E;  4OIN E;  3HOY E;  2Y0S I;  5C44 E;  4Y7N F;  2WAQ K;  3GTL E;  2WB1 I;  2JA7 F;  4A3B E;  4BBR E;  3K7A E;  3GTO E;  3HOU E;  5IYC F;  1TWH E;  2PPB E;  2NVQ F;  3S17 E;  1TWF E;  1SFO F;  4ZH4 E;  4AYB K;  4C2M E;  4A3E E; 
#chains in the Genus database with same CATH homology
 3FKI F;  3S15 F;  1SMY E;  1I6V E;  4A3K F;  1I6H F;  3H0G F;  4A3I F;  4MEY E;  2PMZ K;  3S1N F;  4A3G F;  5TMF E;  2O5I E;  2JA5 F;  3RZO F;  3HOY F;  5D4C E;  5C44 F;  3S1R F;  3GTL F;  4A3D F;  4A3B F;  4BBR F;  3K7A F;  3H3V G;  3GTO F;  3HOU F;  1TWH F;  4KN4 E;  3S17 F;  1TWF F;  3HKZ K;  4Q4Z E;  1YNN K;  4C2M F;  4A3E F;  4C3I F;  4BY1 F;  2E2H F;  5M5W F;  4XSX E;  3PO2 F;  3DXJ E;  4OIP E;  4OIR E;  5C4J F;  5M5Y F;  5M3M F;  5FJ8 F;  3PO3 F;  2A68 E;  3GTK F;  3S1M F;  3GTJ F;  4BXX F;  5FLM F;  1WCM F;  4YFK E;  5D4E E;  2A69 E;  4Y52 F;  4XLP E;  4OIO E;  3S2H F;  4A3C F;  5IYD F;  3EQL E;  3GTG F;  4XSZ E;  4BBS F;  4A3J F;  4X6A F;  2KRX A;  4XLN E;  1ZYR E;  4YFX E;  5IPL E;  4YG2 E;  5IP7 F;  4GZY E;  4KN7 E;  1I3Q F;  2JA8 F;  3S1Q F;  1QKL A;  3GTM F;  3S2D F;  5IP9 F;  5IYB F;  4LK1 E;  2R93 F;  5M5X F;  2JA6 F;  5D4D E;  1IW7 E;  2E2J F;  4A3L F;  4MQ9 E;  4LJZ E;  1YNJ K;  1TWC F;  5M3F F;  4YFN E;  3I4M F;  1HQM E;  4G7O E;  4MEX E;  2O5J E;  2R7Z F;  3GTQ F;  5E18 E;  5C3E F;  2A6E E;  2YU9 F;  4A93 F;  4C3J F;  4QIW K;  2NVT F;  3M4O F;  5E17 E;  3HOV F;  1TWA F;  4BY7 F;  4Q5S E;  3WOD E;  3RZD F;  2B63 F;  4G7H E;  1R9T F;  2CW0 E;  5BYH E;  1Y1V F;  3HOW F;  2NVY F;  2BE5 E;  1Y1W F;  2NVX F;  3HOX F;  2A6H E;  4LK0 E;  4A3F F;  4G7Z E;  3S14 F;  2R92 F;  3M3Y F;  4LLG E;  4JK1 E;  5C4X F;  1I50 F;  5TMC E;  3GTP F;  3CQZ F;  4KMU E;  3HOZ F;  2E2I F;  3S16 F;  4C3H F;  2VUM F;  4A3M F;  1K83 F;  1TWG F;  4OIQ E;  4OIN E;  2Y0S I;  4Y7N F;  2WAQ K;  2WB1 I;  2JA7 F;  5IYC F;  2PPB E;  2NVQ F;  1SFO F;  4ZH4 E;  4AYB K;  3I4N F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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