2BMLA

Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
125
structure length
125
Chain Sequence
YPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGTLADRPEFTVEPDGLITVK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ofloxacin-Like Antibiotics Inhibit Pneumococcal Cell Wall-Degrading Virulence Factors
pubmed doi rcsb
molecule keywords AUTOLYSIN
molecule tags Choline-binding domain
source organism Streptococcus pneumoniae
total genus 15
structure length 125
sequence length 125
chains with identical sequence B
ec nomenclature ec 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
pdb deposition date 2005-03-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01473 CW_binding_1 Putative cell wall binding repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.270.10 Mainly Beta Ribbon left handed beta-beta-3-solenoid Cholin Binding 2bmlA00
2J8GA 2V04A 4TVCA 2VYUA 4TVDA 3HIAA 4TTUA 2G7CA 2BMLA 2X8MA 2X8PA 2J8FA 1H8GA 3KLLA 1H09A 3TTOA 2IXUA 4NC2A 3HZ3A 3TTQA 1GVMA 4NBXA 4X36A 4NBZA 2V05A 4NC0A 1HCXA 2QJ6A 2F6EA 1OBAA 2X8OA 3KLKA 2IXVA 4AYGA 4NBYA
chains in the Genus database with same CATH superfamily
2J8GA 2V04A 4TVCA 2VYUA 4TVDA 3HIAA 4TTUA 2G7CA 2BMLA 2X8MA 2X8PA 2J8FA 1H8GA 3KLLA 1H09A 3TTOA 2IXUA 4NC2A 3HZ3A 3TTQA 1GVMA 4NBXA 4X36A 4NBZA 2V05A 4NC0A 1HCXA 2QJ6A 2F6EA 1OBAA 2X8OA 3KLKA 2IXVA 4AYGA 4NBYA
chains in the Genus database with same CATH topology
2J8GA 2V04A 4TVCA 2VYUA 4TVDA 3HIAA 4TTUA 2G7CA 2BMLA 2X8MA 2X8PA 2J8FA 1H8GA 3KLLA 1H09A 3TTOA 2IXUA 4NC2A 3HZ3A 3TTQA 1GVMA 4NBXA 4X36A 4NBZA 2V05A 4NC0A 1HCXA 2QJ6A 2F6EA 1OBAA 2X8OA 3KLKA 2IXVA 4AYGA 4NBYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J8G A;  2V04 A;  4TVC A;  2VYU A;  4TVD A;  3HIA A;  4TTU A;  2G7C A;  2BML A;  2X8M A;  2X8P A;  2J8F A;  1H8G A;  3KLL A;  1H09 A;  3TTO A;  2IXU A;  4NC2 A;  3HZ3 A;  3TTQ A;  1GVM A;  4NBX A;  4X36 A;  4NBZ A;  2V05 A;  4NC0 A;  1HCX A;  2QJ6 A;  2F6E A;  1OBA A;  2X8O A;  3KLK A;  2IXV A;  4AYG A;  4NBY A; 
#chains in the Genus database with same CATH topology
 2J8G A;  2V04 A;  4TVC A;  2VYU A;  4TVD A;  3HIA A;  4TTU A;  2G7C A;  2BML A;  2X8M A;  2X8P A;  2J8F A;  1H8G A;  3KLL A;  1H09 A;  3TTO A;  2IXU A;  4NC2 A;  3HZ3 A;  3TTQ A;  1GVM A;  4NBX A;  4X36 A;  4NBZ A;  2V05 A;  4NC0 A;  1HCX A;  2QJ6 A;  2F6E A;  1OBA A;  2X8O A;  3KLK A;  2IXV A;  4AYG A;  4NBY A; 
#chains in the Genus database with same CATH homology
 2J8G A;  2V04 A;  4TVC A;  2VYU A;  4TVD A;  3HIA A;  4TTU A;  2G7C A;  2BML A;  2X8M A;  2X8P A;  2J8F A;  1H8G A;  3KLL A;  1H09 A;  3TTO A;  2IXU A;  4NC2 A;  3HZ3 A;  3TTQ A;  1GVM A;  4NBX A;  4X36 A;  4NBZ A;  2V05 A;  4NC0 A;  1HCX A;  2QJ6 A;  2F6E A;  1OBA A;  2X8O A;  3KLK A;  2IXV A;  4AYG A;  4NBY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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