2D8XA

Solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
70
structure length
70
Chain Sequence
GSSGSSGCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKASGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the second LIM domain of particularly interesting new Cys-His protein (PINCH)
rcsb
molecule tags Structural protein, cell cycle
source organism Homo sapiens
molecule keywords Protein PINCH
total genus 5
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 2005-12-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 2d8xA00
1IMLA 2CU8A 2LXDA 2EGQA 2CORA 2CUQA 2MBVA 2L6ZC 2D8YA 1X3HA 2D8XA 2XQNT 1B8TA 2MIUA 1IBIA 2CO8A 1A7IA 1RUTX 2JTNA 3IXEB 2DJ7A 1J2OA 2XJYA 2LZUA 2YPAC 1U5SB 2EHEA 2XJZA 1NYPA 2DARA 2O10A 1X64A 1V6GA 1M3VA 2DLOA 1WIGA 1QLIA 2L4ZA 2O13A 4HI8B 1X4LA 2D8ZA 3MMKA 1CXXA 1X68A 2IYBE 4KFZA 2KBXB 1G47A 1WYHA 1X63A 2CUPA 1X62A 1X61A 4JCJA 2L6YB 4HI9B 1X6AA 2CURA 1CTLA 2DFYC 3F6QB
chains in the Genus database with same CATH superfamily
2LXDA 5FXVA 2MBVA 1X3HA 2D8XA 3NILA 3NIHA 1B8TA 1A7IA 2JTNA 2DJ7A 2YPAC 1U5SB 2XJZA 1NYPA 1X64A 3AVSA 3AVRA 1X4LA 3MMKA 2IYBE 1X61A 2L6YB 2DFYC 2CURA 3NISA 3F6QB 5LKXA 4UF0B 4ASKA 1IBIA 2DARA 5LKUA 1M3VA 1WIGA 1QLIA 5FY1A 5FP3A 5FXWA 3ZPOA 5LKTA 1CXXA 1X68A 4EYUA 4KFZA 1G47A 5FXXA 1X6AA 1CTLA 5FY0A 2EGQA 2CORA 2D8YA 2LZUA 2O10A 2DLOA 2D8ZA 3NIKA 1WYHA 4EZHA 1X62A 4HI9B 4UF0A 4HI8B 5FYMA 5A1LA 1IMLA 2CU8A 5FXZA 2CUQA 5FY7A 5LKZA 2XQNT 2MIUA 2CO8A 3ZLIA 1RUTX 3IXEB 1J2OA 2XJYA 2EHEA 4EZ4A 1V6GA 2L4ZA 2O13A 3NIJA 3NIMA 2KBXB 4BHWA 2XUEA 1X63A 2CUPA 4JCJA 3NINA 2L6ZC
chains in the Genus database with same CATH topology
2LXDA 5FXVA 2MBVA 1X3HA 2D8XA 3NILA 3NIHA 1B8TA 1A7IA 2JTNA 2DJ7A 2YPAC 1U5SB 2XJZA 1NYPA 1X64A 3AVSA 3AVRA 1X4LA 3MMKA 2IYBE 1X61A 2L6YB 2DFYC 2CURA 3NISA 3F6QB 5LKXA 4UF0B 4ASKA 1IBIA 2DARA 5LKUA 1M3VA 1WIGA 1QLIA 5FY1A 5FP3A 5FXWA 3ZPOA 5LKTA 1CXXA 1X68A 4EYUA 4KFZA 1G47A 5FXXA 1X6AA 1CTLA 5FY0A 2EGQA 2CORA 2D8YA 2LZUA 2O10A 2DLOA 2D8ZA 3NIKA 1WYHA 4EZHA 1X62A 4HI9B 4UF0A 4HI8B 5FYMA 5A1LA 1IMLA 2CU8A 5FXZA 2CUQA 5FY7A 5LKZA 2XQNT 2MIUA 2CO8A 3ZLIA 1RUTX 3IXEB 1J2OA 2XJYA 2EHEA 4EZ4A 1V6GA 2L4ZA 2O13A 3NIJA 3NIMA 2KBXB 4BHWA 2XUEA 1X63A 2CUPA 4JCJA 3NINA 2L6ZC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IML A;  2CU8 A;  2LXD A;  2EGQ A;  2COR A;  2CUQ A;  2MBV A;  2L6Z C;  2D8Y A;  1X3H A;  2D8X A;  2XQN T;  1B8T A;  2MIU A;  1IBI A;  2CO8 A;  1A7I A;  1RUT X;  2JTN A;  3IXE B;  2DJ7 A;  1J2O A;  2XJY A;  2LZU A;  2YPA C;  1U5S B;  2EHE A;  2XJZ A;  1NYP A;  2DAR A;  2O10 A;  1X64 A;  1V6G A;  1M3V A;  2DLO A;  1WIG A;  1QLI A;  2L4Z A;  2O13 A;  4HI8 B;  1X4L A;  2D8Z A;  3MMK A;  1CXX A;  1X68 A;  2IYB E;  4KFZ A;  2KBX B;  1G47 A;  1WYH A;  1X63 A;  2CUP A;  1X62 A;  1X61 A;  4JCJ A;  2L6Y B;  4HI9 B;  1X6A A;  2CUR A;  1CTL A;  2DFY C;  3F6Q B; 
#chains in the Genus database with same CATH topology
 2LXD A;  5FXV A;  2MBV A;  1X3H A;  2D8X A;  3NIL A;  3NIH A;  1B8T A;  1A7I A;  2JTN A;  2DJ7 A;  2YPA C;  1U5S B;  2XJZ A;  1NYP A;  1X64 A;  3AVS A;  3AVR A;  1X4L A;  3MMK A;  2IYB E;  1X61 A;  2L6Y B;  2DFY C;  2CUR A;  3NIS A;  3F6Q B;  5LKX A;  4UF0 B;  4ASK A;  1IBI A;  2DAR A;  5LKU A;  1M3V A;  1WIG A;  1QLI A;  5FY1 A;  5FP3 A;  5FXW A;  3ZPO A;  5LKT A;  1CXX A;  1X68 A;  4EYU A;  4KFZ A;  1G47 A;  5FXX A;  1X6A A;  1CTL A;  5FY0 A;  2EGQ A;  2COR A;  2D8Y A;  2LZU A;  2O10 A;  2DLO A;  2D8Z A;  3NIK A;  1WYH A;  4EZH A;  1X62 A;  4HI9 B;  4UF0 A;  4HI8 B;  5FYM A;  5A1L A;  1IML A;  2CU8 A;  5FXZ A;  2CUQ A;  5FY7 A;  5LKZ A;  2XQN T;  2MIU A;  2CO8 A;  3ZLI A;  1RUT X;  3IXE B;  1J2O A;  2XJY A;  2EHE A;  4EZ4 A;  1V6G A;  2L4Z A;  2O13 A;  3NIJ A;  3NIM A;  2KBX B;  4BHW A;  2XUE A;  1X63 A;  2CUP A;  4JCJ A;  3NIN A;  2L6Z C; 
#chains in the Genus database with same CATH homology
 2LXD A;  5FXV A;  2MBV A;  1X3H A;  2D8X A;  3NIL A;  3NIH A;  1B8T A;  1A7I A;  2JTN A;  2DJ7 A;  2YPA C;  1U5S B;  2XJZ A;  1NYP A;  1X64 A;  3AVS A;  3AVR A;  1X4L A;  3MMK A;  2IYB E;  1X61 A;  2L6Y B;  2DFY C;  2CUR A;  3NIS A;  3F6Q B;  5LKX A;  4UF0 B;  4ASK A;  1IBI A;  2DAR A;  5LKU A;  1M3V A;  1WIG A;  1QLI A;  5FY1 A;  5FP3 A;  5FXW A;  3ZPO A;  5LKT A;  1CXX A;  1X68 A;  4EYU A;  4KFZ A;  1G47 A;  5FXX A;  1X6A A;  1CTL A;  5FY0 A;  2EGQ A;  2COR A;  2D8Y A;  2LZU A;  2O10 A;  2DLO A;  2D8Z A;  3NIK A;  1WYH A;  4EZH A;  1X62 A;  4HI9 B;  4UF0 A;  4HI8 B;  5FYM A;  5A1L A;  1IML A;  2CU8 A;  5FXZ A;  2CUQ A;  5FY7 A;  5LKZ A;  2XQN T;  2MIU A;  2CO8 A;  3ZLI A;  1RUT X;  3IXE B;  1J2O A;  2XJY A;  2EHE A;  4EZ4 A;  1V6G A;  2L4Z A;  2O13 A;  3NIJ A;  3NIM A;  2KBX B;  4BHW A;  2XUE A;  1X63 A;  2CUP A;  4JCJ A;  3NIN A;  2L6Z C; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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