2DDIA

Nmr structure of the second kunitz domain of human wfikkn1
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
70
structure length
70
Chain Sequence
EAEAEFTDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVVDHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords WAP, follistatin/kazal, immunoglobulin, kunitz and netrin do
total genus 15
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 2006-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 2ddiA00
1Y62A 5JB7A 4BD9B 4Y0YI 5JB4A 4DTGK 1YKTB 2FI3I 1AAPA 2CA7A 4WWYC 1TAPA 3BYBA 2HEXA 3TGII 1D0DA 1P2II 1OA65 3BTMI 3LDIA 2M99A 4Y0ZI 3OFWA 1FANA 1JC6A 2PTCI 2R9PE 1NAGA 1CO7I 1BRBI 1T8NB 2DDJA 3AUDA 4TPII 1TCPA 3AUIA 1KUNA 1TFXC 3BTWI 2ODYE 4PTIA 4BNRI 2JOTA 3P92E 1BF0A 4ISLB 3FP7J 1CBWD 1BTHP 4WXVC 4Y10I 1BZ5A 2UUYB 2J6DA 3AUGA 1LD5A 1BRCI 1AALA 1OA55 1MTND 1SHPA 3BTEI 1KNTA 3LDJA 1TOCR 3P95E 1P2JI 1P2MB 1P2OB 3D65I 1DTXA 3BTGI 3FP8I 2KAII 3GYMI 3BTHI 4U30W 1B0CA 1ZJDB 2M01A 4U32X 7PTIA 3LDMA 3UOUB 2ZJXA 1DTKA 1BPTA 1G6XA 1KTHA 2FTMB 3T62D 4Y11I 4NTXB 1TAWB 3BTQI 5JB5A 1ZR0B 2UUXA 1BIKA 3TGKI 1CA0D 3AUCA 1P2QB 1YLDB 4ISNB 3OTJI 1EJMB 9PTIA 1QLQA 2FTLI 2KCRA 1DENA 1D0DB 4DG4C 1BTIA 1EAWB 1KIGI 2IJOI 3TPII 1JV9A 3L3TE 5PTIA 4BQDA 1IRHA 3M7QB 1PITA 1YC0I 1TPAI 4ISOB 2LFKA 1T7CB 3AUHA 1BHCA 2LFLA 1K6UA 8PTIA 1F7ZI 3L33E 1JV8A 2RA3C 1P2KI 1ADZA 2FI5I 3U1JE 1F5RI 3CI7A 1T8OB 2W8XA 3WNYA 2TPII 2TGPI 6PTIA 1FAKI 3BTTI 1FY8I 1UUBA 3BTKI 4NTWB 1DEMA 1UUAA 1BPIA 1YLCB 3BTDI 5C67C 3AUEA 3TGJI 3UIRC 1T8LB 2KNTA 1BZXI 1T8MB 5JB6A 3BTFI 1BUNB 2DDIA 3AUBA 1LD6A 1P2NB 3FP6I 4NTYB 2ZVXA 2FI4I
chains in the Genus database with same CATH superfamily
1Y62A 5JB7A 4BD9B 4Y0YI 5JB4A 4DTGK 1YKTB 2FI3I 1AAPA 2CA7A 4WWYC 1TAPA 3BYBA 2HEXA 3TGII 1D0DA 1P2II 1OA65 3BTMI 3LDIA 2M99A 4Y0ZI 3OFWA 1FANA 1JC6A 2PTCI 2R9PE 1NAGA 1CO7I 1BRBI 1T8NB 2DDJA 3AUDA 4TPII 1TCPA 3AUIA 1KUNA 1TFXC 3BTWI 2ODYE 4PTIA 4BNRI 2JOTA 3P92E 1BF0A 4ISLB 3FP7J 1CBWD 1BTHP 4WXVC 4Y10I 1BZ5A 2UUYB 2J6DA 3AUGA 1LD5A 1BRCI 1AALA 1OA55 1MTND 1SHPA 3BTEI 1KNTA 3LDJA 1TOCR 3P95E 1P2JI 1P2MB 1P2OB 3D65I 1DTXA 3BTGI 3FP8I 2KAII 3GYMI 3BTHI 4U30W 1B0CA 1ZJDB 2M01A 4U32X 7PTIA 3LDMA 3UOUB 2ZJXA 1DTKA 1BPTA 1G6XA 1KTHA 2FTMB 3T62D 4Y11I 4NTXB 1TAWB 3BTQI 5JB5A 1ZR0B 2UUXA 1BIKA 3TGKI 1CA0D 3AUCA 1P2QB 1YLDB 4ISNB 3OTJI 1EJMB 9PTIA 1QLQA 2FTLI 2KCRA 1DENA 1D0DB 4DG4C 1BTIA 1EAWB 1KIGI 2IJOI 3TPII 1JV9A 3L3TE 5PTIA 4BQDA 1IRHA 3M7QB 1PITA 1YC0I 1TPAI 4ISOB 2LFKA 1T7CB 3AUHA 1BHCA 2LFLA 1K6UA 8PTIA 1F7ZI 3L33E 1JV8A 2RA3C 1P2KI 1ADZA 2FI5I 3U1JE 1F5RI 3CI7A 1T8OB 2W8XA 3WNYA 2TPII 2TGPI 6PTIA 1FAKI 3BTTI 1FY8I 1UUBA 3BTKI 4NTWB 1DEMA 1UUAA 1BPIA 1YLCB 3BTDI 5C67C 3AUEA 3TGJI 3UIRC 1T8LB 2KNTA 1BZXI 1T8MB 5JB6A 3BTFI 1BUNB 2DDIA 3AUBA 1LD6A 1P2NB 3FP6I 4NTYB 2ZVXA 2FI4I
chains in the Genus database with same CATH topology
1Y62A 5JB7A 4BD9B 4Y0YI 5JB4A 4DTGK 1YKTB 2FI3I 1AAPA 2CA7A 4WWYC 1TAPA 3BYBA 2HEXA 3TGII 1D0DA 1P2II 1OA65 3BTMI 3LDIA 2M99A 4Y0ZI 3OFWA 1FANA 1JC6A 2PTCI 2R9PE 1NAGA 1CO7I 1BRBI 1T8NB 2DDJA 3AUDA 4TPII 1TCPA 3AUIA 1KUNA 1TFXC 3BTWI 2ODYE 4PTIA 4BNRI 2JOTA 3P92E 1BF0A 4ISLB 3FP7J 1CBWD 1BTHP 4WXVC 4Y10I 1BZ5A 2UUYB 2J6DA 3AUGA 1LD5A 1BRCI 1AALA 1OA55 1MTND 1SHPA 3BTEI 1KNTA 3LDJA 1TOCR 3P95E 1P2JI 1P2MB 1P2OB 3D65I 1DTXA 3BTGI 3FP8I 2KAII 3GYMI 3BTHI 4U30W 1B0CA 1ZJDB 2M01A 4U32X 7PTIA 3LDMA 3UOUB 2ZJXA 1DTKA 1BPTA 1G6XA 1KTHA 2FTMB 3T62D 4Y11I 4NTXB 1TAWB 3BTQI 5JB5A 1ZR0B 2UUXA 1BIKA 3TGKI 1CA0D 3AUCA 1P2QB 1YLDB 4ISNB 3OTJI 1EJMB 9PTIA 1QLQA 2FTLI 2KCRA 1DENA 1D0DB 4DG4C 1BTIA 1EAWB 1KIGI 2IJOI 3TPII 1JV9A 3L3TE 5PTIA 4BQDA 1IRHA 3M7QB 1PITA 1YC0I 1TPAI 4ISOB 2LFKA 1T7CB 3AUHA 1BHCA 2LFLA 1K6UA 8PTIA 1F7ZI 3L33E 1JV8A 2RA3C 1P2KI 1ADZA 2FI5I 3U1JE 1F5RI 3CI7A 1T8OB 2W8XA 3WNYA 2TPII 2TGPI 6PTIA 1FAKI 3BTTI 1FY8I 1UUBA 3BTKI 4NTWB 1DEMA 1UUAA 1BPIA 1YLCB 3BTDI 5C67C 3AUEA 3TGJI 3UIRC 1T8LB 2KNTA 1BZXI 1T8MB 5JB6A 3BTFI 1BUNB 2DDIA 3AUBA 1LD6A 1P2NB 3FP6I 4NTYB 2ZVXA 2FI4I
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y62 A;  5JB7 A;  4BD9 B;  4Y0Y I;  5JB4 A;  4DTG K;  1YKT B;  2FI3 I;  1AAP A;  2CA7 A;  4WWY C;  1TAP A;  3BYB A;  2HEX A;  3TGI I;  1D0D A;  1P2I I;  1OA6 5;  3BTM I;  3LDI A;  2M99 A;  4Y0Z I;  3OFW A;  1FAN A;  1JC6 A;  2PTC I;  2R9P E;  1NAG A;  1CO7 I;  1BRB I;  1T8N B;  2DDJ A;  3AUD A;  4TPI I;  1TCP A;  3AUI A;  1KUN A;  1TFX C;  3BTW I;  2ODY E;  4PTI A;  4BNR I;  2JOT A;  3P92 E;  1BF0 A;  4ISL B;  3FP7 J;  1CBW D;  1BTH P;  4WXV C;  4Y10 I;  1BZ5 A;  2UUY B;  2J6D A;  3AUG A;  1LD5 A;  1BRC I;  1AAL A;  1OA5 5;  1MTN D;  1SHP A;  3BTE I;  1KNT A;  3LDJ A;  1TOC R;  3P95 E;  1P2J I;  1P2M B;  1P2O B;  3D65 I;  1DTX A;  3BTG I;  3FP8 I;  2KAI I;  3GYM I;  3BTH I;  4U30 W;  1B0C A;  1ZJD B;  2M01 A;  4U32 X;  7PTI A;  3LDM A;  3UOU B;  2ZJX A;  1DTK A;  1BPT A;  1G6X A;  1KTH A;  2FTM B;  3T62 D;  4Y11 I;  4NTX B;  1TAW B;  3BTQ I;  5JB5 A;  1ZR0 B;  2UUX A;  1BIK A;  3TGK I;  1CA0 D;  3AUC A;  1P2Q B;  1YLD B;  4ISN B;  3OTJ I;  1EJM B;  9PTI A;  1QLQ A;  2FTL I;  2KCR A;  1DEN A;  1D0D B;  4DG4 C;  1BTI A;  1EAW B;  1KIG I;  2IJO I;  3TPI I;  1JV9 A;  3L3T E;  5PTI A;  4BQD A;  1IRH A;  3M7Q B;  1PIT A;  1YC0 I;  1TPA I;  4ISO B;  2LFK A;  1T7C B;  3AUH A;  1BHC A;  2LFL A;  1K6U A;  8PTI A;  1F7Z I;  3L33 E;  1JV8 A;  2RA3 C;  1P2K I;  1ADZ A;  2FI5 I;  3U1J E;  1F5R I;  3CI7 A;  1T8O B;  2W8X A;  3WNY A;  2TPI I;  2TGP I;  6PTI A;  1FAK I;  3BTT I;  1FY8 I;  1UUB A;  3BTK I;  4NTW B;  1DEM A;  1UUA A;  1BPI A;  1YLC B;  3BTD I;  5C67 C;  3AUE A;  3TGJ I;  3UIR C;  1T8L B;  2KNT A;  1BZX I;  1T8M B;  5JB6 A;  3BTF I;  1BUN B;  2DDI A;  3AUB A;  1LD6 A;  1P2N B;  3FP6 I;  4NTY B;  2ZVX A;  2FI4 I; 
#chains in the Genus database with same CATH topology
 1Y62 A;  5JB7 A;  4BD9 B;  4Y0Y I;  5JB4 A;  4DTG K;  1YKT B;  2FI3 I;  1AAP A;  2CA7 A;  4WWY C;  1TAP A;  3BYB A;  2HEX A;  3TGI I;  1D0D A;  1P2I I;  1OA6 5;  3BTM I;  3LDI A;  2M99 A;  4Y0Z I;  3OFW A;  1FAN A;  1JC6 A;  2PTC I;  2R9P E;  1NAG A;  1CO7 I;  1BRB I;  1T8N B;  2DDJ A;  3AUD A;  4TPI I;  1TCP A;  3AUI A;  1KUN A;  1TFX C;  3BTW I;  2ODY E;  4PTI A;  4BNR I;  2JOT A;  3P92 E;  1BF0 A;  4ISL B;  3FP7 J;  1CBW D;  1BTH P;  4WXV C;  4Y10 I;  1BZ5 A;  2UUY B;  2J6D A;  3AUG A;  1LD5 A;  1BRC I;  1AAL A;  1OA5 5;  1MTN D;  1SHP A;  3BTE I;  1KNT A;  3LDJ A;  1TOC R;  3P95 E;  1P2J I;  1P2M B;  1P2O B;  3D65 I;  1DTX A;  3BTG I;  3FP8 I;  2KAI I;  3GYM I;  3BTH I;  4U30 W;  1B0C A;  1ZJD B;  2M01 A;  4U32 X;  7PTI A;  3LDM A;  3UOU B;  2ZJX A;  1DTK A;  1BPT A;  1G6X A;  1KTH A;  2FTM B;  3T62 D;  4Y11 I;  4NTX B;  1TAW B;  3BTQ I;  5JB5 A;  1ZR0 B;  2UUX A;  1BIK A;  3TGK I;  1CA0 D;  3AUC A;  1P2Q B;  1YLD B;  4ISN B;  3OTJ I;  1EJM B;  9PTI A;  1QLQ A;  2FTL I;  2KCR A;  1DEN A;  1D0D B;  4DG4 C;  1BTI A;  1EAW B;  1KIG I;  2IJO I;  3TPI I;  1JV9 A;  3L3T E;  5PTI A;  4BQD A;  1IRH A;  3M7Q B;  1PIT A;  1YC0 I;  1TPA I;  4ISO B;  2LFK A;  1T7C B;  3AUH A;  1BHC A;  2LFL A;  1K6U A;  8PTI A;  1F7Z I;  3L33 E;  1JV8 A;  2RA3 C;  1P2K I;  1ADZ A;  2FI5 I;  3U1J E;  1F5R I;  3CI7 A;  1T8O B;  2W8X A;  3WNY A;  2TPI I;  2TGP I;  6PTI A;  1FAK I;  3BTT I;  1FY8 I;  1UUB A;  3BTK I;  4NTW B;  1DEM A;  1UUA A;  1BPI A;  1YLC B;  3BTD I;  5C67 C;  3AUE A;  3TGJ I;  3UIR C;  1T8L B;  2KNT A;  1BZX I;  1T8M B;  5JB6 A;  3BTF I;  1BUN B;  2DDI A;  3AUB A;  1LD6 A;  1P2N B;  3FP6 I;  4NTY B;  2ZVX A;  2FI4 I; 
#chains in the Genus database with same CATH homology
 1Y62 A;  5JB7 A;  4BD9 B;  4Y0Y I;  5JB4 A;  4DTG K;  1YKT B;  2FI3 I;  1AAP A;  2CA7 A;  4WWY C;  1TAP A;  3BYB A;  2HEX A;  3TGI I;  1D0D A;  1P2I I;  1OA6 5;  3BTM I;  3LDI A;  2M99 A;  4Y0Z I;  3OFW A;  1FAN A;  1JC6 A;  2PTC I;  2R9P E;  1NAG A;  1CO7 I;  1BRB I;  1T8N B;  2DDJ A;  3AUD A;  4TPI I;  1TCP A;  3AUI A;  1KUN A;  1TFX C;  3BTW I;  2ODY E;  4PTI A;  4BNR I;  2JOT A;  3P92 E;  1BF0 A;  4ISL B;  3FP7 J;  1CBW D;  1BTH P;  4WXV C;  4Y10 I;  1BZ5 A;  2UUY B;  2J6D A;  3AUG A;  1LD5 A;  1BRC I;  1AAL A;  1OA5 5;  1MTN D;  1SHP A;  3BTE I;  1KNT A;  3LDJ A;  1TOC R;  3P95 E;  1P2J I;  1P2M B;  1P2O B;  3D65 I;  1DTX A;  3BTG I;  3FP8 I;  2KAI I;  3GYM I;  3BTH I;  4U30 W;  1B0C A;  1ZJD B;  2M01 A;  4U32 X;  7PTI A;  3LDM A;  3UOU B;  2ZJX A;  1DTK A;  1BPT A;  1G6X A;  1KTH A;  2FTM B;  3T62 D;  4Y11 I;  4NTX B;  1TAW B;  3BTQ I;  5JB5 A;  1ZR0 B;  2UUX A;  1BIK A;  3TGK I;  1CA0 D;  3AUC A;  1P2Q B;  1YLD B;  4ISN B;  3OTJ I;  1EJM B;  9PTI A;  1QLQ A;  2FTL I;  2KCR A;  1DEN A;  1D0D B;  4DG4 C;  1BTI A;  1EAW B;  1KIG I;  2IJO I;  3TPI I;  1JV9 A;  3L3T E;  5PTI A;  4BQD A;  1IRH A;  3M7Q B;  1PIT A;  1YC0 I;  1TPA I;  4ISO B;  2LFK A;  1T7C B;  3AUH A;  1BHC A;  2LFL A;  1K6U A;  8PTI A;  1F7Z I;  3L33 E;  1JV8 A;  2RA3 C;  1P2K I;  1ADZ A;  2FI5 I;  3U1J E;  1F5R I;  3CI7 A;  1T8O B;  2W8X A;  3WNY A;  2TPI I;  2TGP I;  6PTI A;  1FAK I;  3BTT I;  1FY8 I;  1UUB A;  3BTK I;  4NTW B;  1DEM A;  1UUA A;  1BPI A;  1YLC B;  3BTD I;  5C67 C;  3AUE A;  3TGJ I;  3UIR C;  1T8L B;  2KNT A;  1BZX I;  1T8M B;  5JB6 A;  3BTF I;  1BUN B;  2DDI A;  3AUB A;  1LD6 A;  1P2N B;  3FP6 I;  4NTY B;  2ZVX A;  2FI4 I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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