2DYUA

Helicobacter pylori formamidase amif contains a fine-tuned cysteine-glutamate-lysine catalytic triad
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
322
structure length
322
Chain Sequence
GFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGEIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCICHDGMIPELAREAAYKGCNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEGQICNFDGTTLVQGHRNPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGYVAKPGGEHDAGLTYIKDLAAGKYKLPWEDHMKIKDGSIYGYPTTGGRFGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Helicobacter pylori
publication title Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad
pubmed doi rcsb
molecule keywords Formamidase
total genus 102
structure length 322
sequence length 322
chains with identical sequence B
ec nomenclature ec 3.5.1.49: Formamidase.
pdb deposition date 2006-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 2dyuA01
2E11A 4IZSA 1UF7A 3HKXA 3SYTA 3SDBA 3P8KA 5H8JA 2E2KA 4HG3A 3KLCA 1ERZA 2GGLA 2DYVA 4HGDA 2E2LA 4GYLA 4IZWA 4F4HA 4KZFA 1UF5A 3SZGA 4CYFA 1F89A 4CYYA 3WUYA 5JQNA 1EMSA 3SEQA 3ILVA 1J31A 3N05A 4GYNA 2VHHA 2W1VA 4H5UA 1UF8A 4LF0A 2UXYA 2DYUA 5H8IA 3KI8A 4CYGA 4IZTA 2PLQA 2GGKA 2VHIA 5H8LA 5KHAA 3IVZA 4IZVA 3SEZA 5H8KA 3IW3A 4IZUA 1FO6A 3DLAA 4HG5A 1UF4A
chains in the Genus database with same CATH superfamily
2E11A 4IZSA 1UF7A 3HKXA 3SYTA 3SDBA 3P8KA 5H8JA 2E2KA 4HG3A 3KLCA 1ERZA 2GGLA 2DYVA 4HGDA 2E2LA 4GYLA 4IZWA 4F4HA 4KZFA 1UF5A 3SZGA 4CYFA 1F89A 4CYYA 3WUYA 5JQNA 1EMSA 3SEQA 3ILVA 1J31A 3N05A 4GYNA 2VHHA 2W1VA 4H5UA 1UF8A 4LF0A 2UXYA 2DYUA 5H8IA 3KI8A 4CYGA 4IZTA 2PLQA 2GGKA 2VHIA 5H8LA 5KHAA 3IVZA 4IZVA 3SEZA 5H8KA 3IW3A 4IZUA 1FO6A 3DLAA 4HG5A 1UF4A
chains in the Genus database with same CATH topology
2E11A 4IZSA 1UF7A 3HKXA 3SYTA 3SDBA 3P8KA 5H8JA 2E2KA 4HG3A 3KLCA 1ERZA 2GGLA 2DYVA 4HGDA 2E2LA 4GYLA 4IZWA 4F4HA 4KZFA 1UF5A 3SZGA 4CYFA 1F89A 4CYYA 3WUYA 5JQNA 1EMSA 3SEQA 3ILVA 1J31A 3N05A 4GYNA 2VHHA 2W1VA 4H5UA 1UF8A 4LF0A 2UXYA 2DYUA 5H8IA 3KI8A 4CYGA 4IZTA 2PLQA 2GGKA 2VHIA 5H8LA 5KHAA 3IVZA 4IZVA 3SEZA 5H8KA 3IW3A 4IZUA 1FO6A 3DLAA 4HG5A 1UF4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E11 A;  4IZS A;  1UF7 A;  3HKX A;  3SYT A;  3SDB A;  3P8K A;  5H8J A;  2E2K A;  4HG3 A;  3KLC A;  1ERZ A;  2GGL A;  2DYV A;  4HGD A;  2E2L A;  4GYL A;  4IZW A;  4F4H A;  4KZF A;  1UF5 A;  3SZG A;  4CYF A;  1F89 A;  4CYY A;  3WUY A;  5JQN A;  1EMS A;  3SEQ A;  3ILV A;  1J31 A;  3N05 A;  4GYN A;  2VHH A;  2W1V A;  4H5U A;  1UF8 A;  4LF0 A;  2UXY A;  2DYU A;  5H8I A;  3KI8 A;  4CYG A;  4IZT A;  2PLQ A;  2GGK A;  2VHI A;  5H8L A;  5KHA A;  3IVZ A;  4IZV A;  3SEZ A;  5H8K A;  3IW3 A;  4IZU A;  1FO6 A;  3DLA A;  4HG5 A;  1UF4 A; 
#chains in the Genus database with same CATH topology
 2E11 A;  4IZS A;  1UF7 A;  3HKX A;  3SYT A;  3SDB A;  3P8K A;  5H8J A;  2E2K A;  4HG3 A;  3KLC A;  1ERZ A;  2GGL A;  2DYV A;  4HGD A;  2E2L A;  4GYL A;  4IZW A;  4F4H A;  4KZF A;  1UF5 A;  3SZG A;  4CYF A;  1F89 A;  4CYY A;  3WUY A;  5JQN A;  1EMS A;  3SEQ A;  3ILV A;  1J31 A;  3N05 A;  4GYN A;  2VHH A;  2W1V A;  4H5U A;  1UF8 A;  4LF0 A;  2UXY A;  2DYU A;  5H8I A;  3KI8 A;  4CYG A;  4IZT A;  2PLQ A;  2GGK A;  2VHI A;  5H8L A;  5KHA A;  3IVZ A;  4IZV A;  3SEZ A;  5H8K A;  3IW3 A;  4IZU A;  1FO6 A;  3DLA A;  4HG5 A;  1UF4 A; 
#chains in the Genus database with same CATH homology
 2E11 A;  4IZS A;  1UF7 A;  3HKX A;  3SYT A;  3SDB A;  3P8K A;  5H8J A;  2E2K A;  4HG3 A;  3KLC A;  1ERZ A;  2GGL A;  2DYV A;  4HGD A;  2E2L A;  4GYL A;  4IZW A;  4F4H A;  4KZF A;  1UF5 A;  3SZG A;  4CYF A;  1F89 A;  4CYY A;  3WUY A;  5JQN A;  1EMS A;  3SEQ A;  3ILV A;  1J31 A;  3N05 A;  4GYN A;  2VHH A;  2W1V A;  4H5U A;  1UF8 A;  4LF0 A;  2UXY A;  2DYU A;  5H8I A;  3KI8 A;  4CYG A;  4IZT A;  2PLQ A;  2GGK A;  2VHI A;  5H8L A;  5KHA A;  3IVZ A;  4IZV A;  3SEZ A;  5H8K A;  3IW3 A;  4IZU A;  1FO6 A;  3DLA A;  4HG5 A;  1UF4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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