2E2LA

Helicobacter pylori formamidase amif contains a fine-tuned cysteine-glutamate-lysine catalytic triad
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
322
structure length
317
Chain Sequence
GFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGEIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCISHDGMIPELAREAAYKGCNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYYFGEGQICNFDGTTLVQGHRNPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGYVAKPGGEHDAGLTYIKDLAAGKYKLPWEDHMKIKDGSIYGYPTTGGRFGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad
pubmed doi rcsb
molecule tags Hydrolase
source organism Helicobacter pylori
molecule keywords Formamidase
total genus 97
structure length 317
sequence length 322
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.1.49: Formamidase.
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 2e2lA01
3SZGA 2W1VA 1UF5A 2E2KA 5H8LA 2GGLA 4HG3A 4IZWA 4IZVA 1UF7A 3WUYA 4CYGA 4GYNA 1J31A 5KHAA 1F89A 2UXYA 2VHHA 3SYTA 2E11A 3N05A 4F4HA 3DLAA 3HKXA 4HG5A 1UF8A 4IZUA 3SEQA 2DYUA 3IVZA 3KLCA 3SEZA 3SDBA 4IZTA 4H5UA 3P8KA 1EMSA 5H8KA 4LF0A 4CYYA 4GYLA 1UF4A 5H8IA 2VHIA 4KZFA 2E2LA 3ILVA 4CYFA 5JQNA 1FO6A 4HGDA 2GGKA 3IW3A 3KI8A 2PLQA 4IZSA 2DYVA 1ERZA 5H8JA
chains in the Genus database with same CATH superfamily
3SZGA 2W1VA 1UF5A 2E2KA 5H8LA 2GGLA 4HG3A 4IZWA 4IZVA 1UF7A 3WUYA 4CYGA 4GYNA 1J31A 5KHAA 1F89A 2UXYA 2VHHA 3SYTA 2E11A 3N05A 4F4HA 3DLAA 3HKXA 4HG5A 1UF8A 4IZUA 3SEQA 2DYUA 3IVZA 3KLCA 3SEZA 3SDBA 4IZTA 4H5UA 3P8KA 1EMSA 5H8KA 4LF0A 4CYYA 4GYLA 1UF4A 5H8IA 2VHIA 4KZFA 2E2LA 3ILVA 4CYFA 5JQNA 1FO6A 4HGDA 2GGKA 3IW3A 3KI8A 2PLQA 4IZSA 2DYVA 1ERZA 5H8JA
chains in the Genus database with same CATH topology
3SZGA 2W1VA 1UF5A 2E2KA 5H8LA 2GGLA 4HG3A 4IZWA 4IZVA 1UF7A 3WUYA 4CYGA 4GYNA 1J31A 5KHAA 1F89A 2UXYA 2VHHA 3SYTA 2E11A 3N05A 4F4HA 3DLAA 3HKXA 4HG5A 1UF8A 4IZUA 3SEQA 2DYUA 3IVZA 3KLCA 3SEZA 3SDBA 4IZTA 4H5UA 3P8KA 1EMSA 5H8KA 4LF0A 4CYYA 4GYLA 1UF4A 5H8IA 2VHIA 4KZFA 2E2LA 3ILVA 4CYFA 5JQNA 1FO6A 4HGDA 2GGKA 3IW3A 3KI8A 2PLQA 4IZSA 2DYVA 1ERZA 5H8JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SZG A;  2W1V A;  1UF5 A;  2E2K A;  5H8L A;  2GGL A;  4HG3 A;  4IZW A;  4IZV A;  1UF7 A;  3WUY A;  4CYG A;  4GYN A;  1J31 A;  5KHA A;  1F89 A;  2UXY A;  2VHH A;  3SYT A;  2E11 A;  3N05 A;  4F4H A;  3DLA A;  3HKX A;  4HG5 A;  1UF8 A;  4IZU A;  3SEQ A;  2DYU A;  3IVZ A;  3KLC A;  3SEZ A;  3SDB A;  4IZT A;  4H5U A;  3P8K A;  1EMS A;  5H8K A;  4LF0 A;  4CYY A;  4GYL A;  1UF4 A;  5H8I A;  2VHI A;  4KZF A;  2E2L A;  3ILV A;  4CYF A;  5JQN A;  1FO6 A;  4HGD A;  2GGK A;  3IW3 A;  3KI8 A;  2PLQ A;  4IZS A;  2DYV A;  1ERZ A;  5H8J A; 
#chains in the Genus database with same CATH topology
 3SZG A;  2W1V A;  1UF5 A;  2E2K A;  5H8L A;  2GGL A;  4HG3 A;  4IZW A;  4IZV A;  1UF7 A;  3WUY A;  4CYG A;  4GYN A;  1J31 A;  5KHA A;  1F89 A;  2UXY A;  2VHH A;  3SYT A;  2E11 A;  3N05 A;  4F4H A;  3DLA A;  3HKX A;  4HG5 A;  1UF8 A;  4IZU A;  3SEQ A;  2DYU A;  3IVZ A;  3KLC A;  3SEZ A;  3SDB A;  4IZT A;  4H5U A;  3P8K A;  1EMS A;  5H8K A;  4LF0 A;  4CYY A;  4GYL A;  1UF4 A;  5H8I A;  2VHI A;  4KZF A;  2E2L A;  3ILV A;  4CYF A;  5JQN A;  1FO6 A;  4HGD A;  2GGK A;  3IW3 A;  3KI8 A;  2PLQ A;  4IZS A;  2DYV A;  1ERZ A;  5H8J A; 
#chains in the Genus database with same CATH homology
 3SZG A;  2W1V A;  1UF5 A;  2E2K A;  5H8L A;  2GGL A;  4HG3 A;  4IZW A;  4IZV A;  1UF7 A;  3WUY A;  4CYG A;  4GYN A;  1J31 A;  5KHA A;  1F89 A;  2UXY A;  2VHH A;  3SYT A;  2E11 A;  3N05 A;  4F4H A;  3DLA A;  3HKX A;  4HG5 A;  1UF8 A;  4IZU A;  3SEQ A;  2DYU A;  3IVZ A;  3KLC A;  3SEZ A;  3SDB A;  4IZT A;  4H5U A;  3P8K A;  1EMS A;  5H8K A;  4LF0 A;  4CYY A;  4GYL A;  1UF4 A;  5H8I A;  2VHI A;  4KZF A;  2E2L A;  3ILV A;  4CYF A;  5JQN A;  1FO6 A;  4HGD A;  2GGK A;  3IW3 A;  3KI8 A;  2PLQ A;  4IZS A;  2DYV A;  1ERZ A;  5H8J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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