2E2KA

Helicobacter pylori formamidase amif contains a fine-tuned cysteine-glutamate-lysine catalytic triad
Total Genus 92
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
322
structure length
313
Chain Sequence
GFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGEIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCISHDGMIPELAREAAYKGCNVYIRISGYSQVNDQWILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEGQICNFDGTTLVQGHRPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGGEHDAGLTYKDLAAGKYKLPWEDHMKIKDGSIYGYPTTGGRFGK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad
pubmed doi rcsb
molecule tags Hydrolase
source organism Helicobacter pylori
molecule keywords Formamidase
total genus 92
structure length 313
sequence length 322
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.1.49: Formamidase.
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 2e2kA01
4HG5A 1ERZA 4KZFA 4GYNA 1UF7A 2GGKA 4IZSA 5KHAA 5JQNA 4IZVA 2VHHA 3SZGA 2DYVA 3SEZA 3DLAA 1UF8A 2PLQA 2W1VA 3ILVA 1FO6A 3WUYA 4F4HA 1F89A 3KLCA 3KI8A 1UF5A 4LF0A 2E11A 1UF4A 4HG3A 1J31A 4H5UA 4IZWA 5H8IA 3HKXA 2E2LA 4GYLA 3SYTA 4CYFA 5H8LA 4IZUA 1EMSA 3N05A 5H8KA 3IVZA 2VHIA 3IW3A 3SDBA 3SEQA 4HGDA 4IZTA 3P8KA 4CYYA 5H8JA 2DYUA 4CYGA 2E2KA 2GGLA 2UXYA
chains in the Genus database with same CATH superfamily
4HG5A 1ERZA 4KZFA 4GYNA 1UF7A 2GGKA 4IZSA 5KHAA 5JQNA 4IZVA 2VHHA 3SZGA 2DYVA 3SEZA 3DLAA 1UF8A 2PLQA 2W1VA 3ILVA 1FO6A 3WUYA 4F4HA 1F89A 3KLCA 3KI8A 1UF5A 4LF0A 2E11A 1UF4A 4HG3A 1J31A 4H5UA 4IZWA 5H8IA 3HKXA 2E2LA 4GYLA 3SYTA 4CYFA 5H8LA 4IZUA 1EMSA 3N05A 5H8KA 3IVZA 2VHIA 3IW3A 3SDBA 3SEQA 4HGDA 4IZTA 3P8KA 4CYYA 5H8JA 2DYUA 4CYGA 2E2KA 2GGLA 2UXYA
chains in the Genus database with same CATH topology
4HG5A 1ERZA 4KZFA 4GYNA 1UF7A 2GGKA 4IZSA 5KHAA 5JQNA 4IZVA 2VHHA 3SZGA 2DYVA 3SEZA 3DLAA 1UF8A 2PLQA 2W1VA 3ILVA 1FO6A 3WUYA 4F4HA 1F89A 3KLCA 3KI8A 1UF5A 4LF0A 2E11A 1UF4A 4HG3A 1J31A 4H5UA 4IZWA 5H8IA 3HKXA 2E2LA 4GYLA 3SYTA 4CYFA 5H8LA 4IZUA 1EMSA 3N05A 5H8KA 3IVZA 2VHIA 3IW3A 3SDBA 3SEQA 4HGDA 4IZTA 3P8KA 4CYYA 5H8JA 2DYUA 4CYGA 2E2KA 2GGLA 2UXYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HG5 A;  1ERZ A;  4KZF A;  4GYN A;  1UF7 A;  2GGK A;  4IZS A;  5KHA A;  5JQN A;  4IZV A;  2VHH A;  3SZG A;  2DYV A;  3SEZ A;  3DLA A;  1UF8 A;  2PLQ A;  2W1V A;  3ILV A;  1FO6 A;  3WUY A;  4F4H A;  1F89 A;  3KLC A;  3KI8 A;  1UF5 A;  4LF0 A;  2E11 A;  1UF4 A;  4HG3 A;  1J31 A;  4H5U A;  4IZW A;  5H8I A;  3HKX A;  2E2L A;  4GYL A;  3SYT A;  4CYF A;  5H8L A;  4IZU A;  1EMS A;  3N05 A;  5H8K A;  3IVZ A;  2VHI A;  3IW3 A;  3SDB A;  3SEQ A;  4HGD A;  4IZT A;  3P8K A;  4CYY A;  5H8J A;  2DYU A;  4CYG A;  2E2K A;  2GGL A;  2UXY A; 
#chains in the Genus database with same CATH topology
 4HG5 A;  1ERZ A;  4KZF A;  4GYN A;  1UF7 A;  2GGK A;  4IZS A;  5KHA A;  5JQN A;  4IZV A;  2VHH A;  3SZG A;  2DYV A;  3SEZ A;  3DLA A;  1UF8 A;  2PLQ A;  2W1V A;  3ILV A;  1FO6 A;  3WUY A;  4F4H A;  1F89 A;  3KLC A;  3KI8 A;  1UF5 A;  4LF0 A;  2E11 A;  1UF4 A;  4HG3 A;  1J31 A;  4H5U A;  4IZW A;  5H8I A;  3HKX A;  2E2L A;  4GYL A;  3SYT A;  4CYF A;  5H8L A;  4IZU A;  1EMS A;  3N05 A;  5H8K A;  3IVZ A;  2VHI A;  3IW3 A;  3SDB A;  3SEQ A;  4HGD A;  4IZT A;  3P8K A;  4CYY A;  5H8J A;  2DYU A;  4CYG A;  2E2K A;  2GGL A;  2UXY A; 
#chains in the Genus database with same CATH homology
 4HG5 A;  1ERZ A;  4KZF A;  4GYN A;  1UF7 A;  2GGK A;  4IZS A;  5KHA A;  5JQN A;  4IZV A;  2VHH A;  3SZG A;  2DYV A;  3SEZ A;  3DLA A;  1UF8 A;  2PLQ A;  2W1V A;  3ILV A;  1FO6 A;  3WUY A;  4F4H A;  1F89 A;  3KLC A;  3KI8 A;  1UF5 A;  4LF0 A;  2E11 A;  1UF4 A;  4HG3 A;  1J31 A;  4H5U A;  4IZW A;  5H8I A;  3HKX A;  2E2L A;  4GYL A;  3SYT A;  4CYF A;  5H8L A;  4IZU A;  1EMS A;  3N05 A;  5H8K A;  3IVZ A;  2VHI A;  3IW3 A;  3SDB A;  3SEQ A;  4HGD A;  4IZT A;  3P8K A;  4CYY A;  5H8J A;  2DYU A;  4CYG A;  2E2K A;  2GGL A;  2UXY A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...