2E2LA

Helicobacter pylori formamidase amif contains a fine-tuned cysteine-glutamate-lysine catalytic triad
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
322
structure length
317
Chain Sequence
GFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGEIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCISHDGMIPELAREAAYKGCNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYYFGEGQICNFDGTTLVQGHRNPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGYVAKPGGEHDAGLTYIKDLAAGKYKLPWEDHMKIKDGSIYGYPTTGGRFGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad
pubmed doi rcsb
molecule tags Hydrolase
source organism Helicobacter pylori
molecule keywords Formamidase
total genus 97
structure length 317
sequence length 322
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.1.49: Formamidase.
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 2e2lA01
1ERZA 5JQNA 2DYVA 2GGKA 4GYLA 2PLQA 5H8LA 4IZUA 1F89A 4IZVA 1UF5A 3SEQA 4CYGA 3SEZA 5H8KA 5H8IA 4CYFA 5H8JA 2VHIA 3SZGA 2E2KA 3IW3A 4H5UA 2UXYA 2GGLA 4IZSA 4LF0A 1UF7A 2W1VA 3DLAA 2E2LA 1UF8A 4HG3A 3ILVA 3P8KA 2DYUA 4KZFA 4F4HA 1J31A 2VHHA 3SYTA 3WUYA 1UF4A 3IVZA 4IZTA 2E11A 4IZWA 5KHAA 3KI8A 3KLCA 4HGDA 4CYYA 3SDBA 4HG5A 1FO6A 4GYNA 3HKXA 1EMSA 3N05A
chains in the Genus database with same CATH superfamily
1ERZA 5JQNA 2DYVA 2GGKA 4GYLA 2PLQA 5H8LA 4IZUA 1F89A 4IZVA 1UF5A 3SEQA 4CYGA 3SEZA 5H8KA 5H8IA 4CYFA 5H8JA 2VHIA 3SZGA 2E2KA 3IW3A 4H5UA 2UXYA 2GGLA 4IZSA 4LF0A 1UF7A 2W1VA 3DLAA 2E2LA 1UF8A 4HG3A 3ILVA 3P8KA 2DYUA 4KZFA 4F4HA 1J31A 2VHHA 3SYTA 3WUYA 1UF4A 3IVZA 4IZTA 2E11A 4IZWA 5KHAA 3KI8A 3KLCA 4HGDA 4CYYA 3SDBA 4HG5A 1FO6A 4GYNA 3HKXA 1EMSA 3N05A
chains in the Genus database with same CATH topology
1ERZA 5JQNA 2DYVA 2GGKA 4GYLA 2PLQA 5H8LA 4IZUA 1F89A 4IZVA 1UF5A 3SEQA 4CYGA 3SEZA 5H8KA 5H8IA 4CYFA 5H8JA 2VHIA 3SZGA 2E2KA 3IW3A 4H5UA 2UXYA 2GGLA 4IZSA 4LF0A 1UF7A 2W1VA 3DLAA 2E2LA 1UF8A 4HG3A 3ILVA 3P8KA 2DYUA 4KZFA 4F4HA 1J31A 2VHHA 3SYTA 3WUYA 1UF4A 3IVZA 4IZTA 2E11A 4IZWA 5KHAA 3KI8A 3KLCA 4HGDA 4CYYA 3SDBA 4HG5A 1FO6A 4GYNA 3HKXA 1EMSA 3N05A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ERZ A;  5JQN A;  2DYV A;  2GGK A;  4GYL A;  2PLQ A;  5H8L A;  4IZU A;  1F89 A;  4IZV A;  1UF5 A;  3SEQ A;  4CYG A;  3SEZ A;  5H8K A;  5H8I A;  4CYF A;  5H8J A;  2VHI A;  3SZG A;  2E2K A;  3IW3 A;  4H5U A;  2UXY A;  2GGL A;  4IZS A;  4LF0 A;  1UF7 A;  2W1V A;  3DLA A;  2E2L A;  1UF8 A;  4HG3 A;  3ILV A;  3P8K A;  2DYU A;  4KZF A;  4F4H A;  1J31 A;  2VHH A;  3SYT A;  3WUY A;  1UF4 A;  3IVZ A;  4IZT A;  2E11 A;  4IZW A;  5KHA A;  3KI8 A;  3KLC A;  4HGD A;  4CYY A;  3SDB A;  4HG5 A;  1FO6 A;  4GYN A;  3HKX A;  1EMS A;  3N05 A; 
#chains in the Genus database with same CATH topology
 1ERZ A;  5JQN A;  2DYV A;  2GGK A;  4GYL A;  2PLQ A;  5H8L A;  4IZU A;  1F89 A;  4IZV A;  1UF5 A;  3SEQ A;  4CYG A;  3SEZ A;  5H8K A;  5H8I A;  4CYF A;  5H8J A;  2VHI A;  3SZG A;  2E2K A;  3IW3 A;  4H5U A;  2UXY A;  2GGL A;  4IZS A;  4LF0 A;  1UF7 A;  2W1V A;  3DLA A;  2E2L A;  1UF8 A;  4HG3 A;  3ILV A;  3P8K A;  2DYU A;  4KZF A;  4F4H A;  1J31 A;  2VHH A;  3SYT A;  3WUY A;  1UF4 A;  3IVZ A;  4IZT A;  2E11 A;  4IZW A;  5KHA A;  3KI8 A;  3KLC A;  4HGD A;  4CYY A;  3SDB A;  4HG5 A;  1FO6 A;  4GYN A;  3HKX A;  1EMS A;  3N05 A; 
#chains in the Genus database with same CATH homology
 1ERZ A;  5JQN A;  2DYV A;  2GGK A;  4GYL A;  2PLQ A;  5H8L A;  4IZU A;  1F89 A;  4IZV A;  1UF5 A;  3SEQ A;  4CYG A;  3SEZ A;  5H8K A;  5H8I A;  4CYF A;  5H8J A;  2VHI A;  3SZG A;  2E2K A;  3IW3 A;  4H5U A;  2UXY A;  2GGL A;  4IZS A;  4LF0 A;  1UF7 A;  2W1V A;  3DLA A;  2E2L A;  1UF8 A;  4HG3 A;  3ILV A;  3P8K A;  2DYU A;  4KZF A;  4F4H A;  1J31 A;  2VHH A;  3SYT A;  3WUY A;  1UF4 A;  3IVZ A;  4IZT A;  2E11 A;  4IZW A;  5KHA A;  3KI8 A;  3KLC A;  4HGD A;  4CYY A;  3SDB A;  4HG5 A;  1FO6 A;  4GYN A;  3HKX A;  1EMS A;  3N05 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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