2E2LA

Helicobacter pylori formamidase amif contains a fine-tuned cysteine-glutamate-lysine catalytic triad
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
322
structure length
317
Chain Sequence
GFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGEIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCISHDGMIPELAREAAYKGCNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYYFGEGQICNFDGTTLVQGHRNPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGYVAKPGGEHDAGLTYIKDLAAGKYKLPWEDHMKIKDGSIYGYPTTGGRFGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Helicobacter pylori
publication title Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad
pubmed doi rcsb
molecule keywords Formamidase
total genus 97
structure length 317
sequence length 322
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.1.49: Formamidase.
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 2e2lA01
5H8KA 3SYTA 2GGLA 3IVZA 4GYLA 2E2LA 4IZTA 5H8IA 4IZWA 3SEQA 2DYVA 3SEZA 1ERZA 4CYFA 2PLQA 1FO6A 1J31A 4IZVA 5H8JA 1EMSA 1UF8A 4F4HA 5KHAA 3ILVA 2E2KA 3P8KA 4HG5A 1UF7A 4HG3A 4CYYA 1F89A 2DYUA 3SDBA 3DLAA 4H5UA 2E11A 3WUYA 2VHHA 3SZGA 1UF5A 3IW3A 1UF4A 4HGDA 4IZSA 4IZUA 2VHIA 4KZFA 2UXYA 3KLCA 4LF0A 2GGKA 5H8LA 4GYNA 4CYGA 3KI8A 2W1VA 3HKXA 3N05A 5JQNA
chains in the Genus database with same CATH superfamily
5H8KA 3SYTA 2GGLA 3IVZA 4GYLA 2E2LA 4IZTA 5H8IA 4IZWA 3SEQA 2DYVA 3SEZA 1ERZA 4CYFA 2PLQA 1FO6A 1J31A 4IZVA 5H8JA 1EMSA 1UF8A 4F4HA 5KHAA 3ILVA 2E2KA 3P8KA 4HG5A 1UF7A 4HG3A 4CYYA 1F89A 2DYUA 3SDBA 3DLAA 4H5UA 2E11A 3WUYA 2VHHA 3SZGA 1UF5A 3IW3A 1UF4A 4HGDA 4IZSA 4IZUA 2VHIA 4KZFA 2UXYA 3KLCA 4LF0A 2GGKA 5H8LA 4GYNA 4CYGA 3KI8A 2W1VA 3HKXA 3N05A 5JQNA
chains in the Genus database with same CATH topology
5H8KA 3SYTA 2GGLA 3IVZA 4GYLA 2E2LA 4IZTA 5H8IA 4IZWA 3SEQA 2DYVA 3SEZA 1ERZA 4CYFA 2PLQA 1FO6A 1J31A 4IZVA 5H8JA 1EMSA 1UF8A 4F4HA 5KHAA 3ILVA 2E2KA 3P8KA 4HG5A 1UF7A 4HG3A 4CYYA 1F89A 2DYUA 3SDBA 3DLAA 4H5UA 2E11A 3WUYA 2VHHA 3SZGA 1UF5A 3IW3A 1UF4A 4HGDA 4IZSA 4IZUA 2VHIA 4KZFA 2UXYA 3KLCA 4LF0A 2GGKA 5H8LA 4GYNA 4CYGA 3KI8A 2W1VA 3HKXA 3N05A 5JQNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5H8K A;  3SYT A;  2GGL A;  3IVZ A;  4GYL A;  2E2L A;  4IZT A;  5H8I A;  4IZW A;  3SEQ A;  2DYV A;  3SEZ A;  1ERZ A;  4CYF A;  2PLQ A;  1FO6 A;  1J31 A;  4IZV A;  5H8J A;  1EMS A;  1UF8 A;  4F4H A;  5KHA A;  3ILV A;  2E2K A;  3P8K A;  4HG5 A;  1UF7 A;  4HG3 A;  4CYY A;  1F89 A;  2DYU A;  3SDB A;  3DLA A;  4H5U A;  2E11 A;  3WUY A;  2VHH A;  3SZG A;  1UF5 A;  3IW3 A;  1UF4 A;  4HGD A;  4IZS A;  4IZU A;  2VHI A;  4KZF A;  2UXY A;  3KLC A;  4LF0 A;  2GGK A;  5H8L A;  4GYN A;  4CYG A;  3KI8 A;  2W1V A;  3HKX A;  3N05 A;  5JQN A; 
#chains in the Genus database with same CATH topology
 5H8K A;  3SYT A;  2GGL A;  3IVZ A;  4GYL A;  2E2L A;  4IZT A;  5H8I A;  4IZW A;  3SEQ A;  2DYV A;  3SEZ A;  1ERZ A;  4CYF A;  2PLQ A;  1FO6 A;  1J31 A;  4IZV A;  5H8J A;  1EMS A;  1UF8 A;  4F4H A;  5KHA A;  3ILV A;  2E2K A;  3P8K A;  4HG5 A;  1UF7 A;  4HG3 A;  4CYY A;  1F89 A;  2DYU A;  3SDB A;  3DLA A;  4H5U A;  2E11 A;  3WUY A;  2VHH A;  3SZG A;  1UF5 A;  3IW3 A;  1UF4 A;  4HGD A;  4IZS A;  4IZU A;  2VHI A;  4KZF A;  2UXY A;  3KLC A;  4LF0 A;  2GGK A;  5H8L A;  4GYN A;  4CYG A;  3KI8 A;  2W1V A;  3HKX A;  3N05 A;  5JQN A; 
#chains in the Genus database with same CATH homology
 5H8K A;  3SYT A;  2GGL A;  3IVZ A;  4GYL A;  2E2L A;  4IZT A;  5H8I A;  4IZW A;  3SEQ A;  2DYV A;  3SEZ A;  1ERZ A;  4CYF A;  2PLQ A;  1FO6 A;  1J31 A;  4IZV A;  5H8J A;  1EMS A;  1UF8 A;  4F4H A;  5KHA A;  3ILV A;  2E2K A;  3P8K A;  4HG5 A;  1UF7 A;  4HG3 A;  4CYY A;  1F89 A;  2DYU A;  3SDB A;  3DLA A;  4H5U A;  2E11 A;  3WUY A;  2VHH A;  3SZG A;  1UF5 A;  3IW3 A;  1UF4 A;  4HGD A;  4IZS A;  4IZU A;  2VHI A;  4KZF A;  2UXY A;  3KLC A;  4LF0 A;  2GGK A;  5H8L A;  4GYN A;  4CYG A;  3KI8 A;  2W1V A;  3HKX A;  3N05 A;  5JQN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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