2FUFA

Crystal structure of the sv40 large t antigen origin-binding domain
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
126
structure length
126
Chain Sequence
KVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the simian virus 40 large T-antigen origin-binding domain.
pubmed doi rcsb
molecule keywords Large T antigen
molecule tags Dna binding protein
source organism Simian virus 40
total genus 32
structure length 126
sequence length 126
ec nomenclature
pdb deposition date 2006-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 2fufA00
2FUFA 4GDFA 5CYNA 4FB3A 4LMDA 5BYGA 2ITJA 1M55A 1L5IA 4ZO0A 2IPRA 2TBDA 1UUTA 1L2MA 3QN2A 5D9IA 4FGNA 2NL8A 2HW0A 4LIFA 4NBPA 5DCXA 2ITLA 1Z1DB 4ZQ9A 3QK2A 1RZ9A 1TBDA 3QFQA 2NTCA 2IF9A
chains in the Genus database with same CATH superfamily
2FUFA 4GDFA 5CYNA 3DKYA 4FB3A 4LMDA 5BYGA 2ITJA 1M55A 1L5IA 4ZO0A 2IPRA 4U87A 2TBDA 4KW3A 1R9WA 1KSXA 1UUTA 1L2MA 3QN2A 5D9IA 4FGNA 2NL8A 2HW0A 4LIFA 4NBPA 5DCXA 1KSYA 1F08A 2ITLA 1Z1DB 3DKXA 4ZQ9A 3QK2A 1RZ9A 1TBDA 3QFQA 2NTCA 2IF9A
chains in the Genus database with same CATH topology
2FUFA 4GDFA 5CYNA 3DKYA 4FB3A 4LMDA 5BYGA 2ITJA 1M55A 1L5IA 4ZO0A 2IPRA 4U87A 2TBDA 4KW3A 1R9WA 1KSXA 1UUTA 1L2MA 3QN2A 5D9IA 4FGNA 2NL8A 2HW0A 4LIFA 4NBPA 5DCXA 1KSYA 1F08A 2ITLA 1Z1DB 3DKXA 4ZQ9A 3QK2A 1RZ9A 1TBDA 3QFQA 2NTCA 2IF9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FUF A;  4GDF A;  5CYN A;  4FB3 A;  4LMD A;  5BYG A;  2ITJ A;  1M55 A;  1L5I A;  4ZO0 A;  2IPR A;  2TBD A;  1UUT A;  1L2M A;  3QN2 A;  5D9I A;  4FGN A;  2NL8 A;  2HW0 A;  4LIF A;  4NBP A;  5DCX A;  2ITL A;  1Z1D B;  4ZQ9 A;  3QK2 A;  1RZ9 A;  1TBD A;  3QFQ A;  2NTC A;  2IF9 A; 
#chains in the Genus database with same CATH topology
 2FUF A;  4GDF A;  5CYN A;  3DKY A;  4FB3 A;  4LMD A;  5BYG A;  2ITJ A;  1M55 A;  1L5I A;  4ZO0 A;  2IPR A;  4U87 A;  2TBD A;  4KW3 A;  1R9W A;  1KSX A;  1UUT A;  1L2M A;  3QN2 A;  5D9I A;  4FGN A;  2NL8 A;  2HW0 A;  4LIF A;  4NBP A;  5DCX A;  1KSY A;  1F08 A;  2ITL A;  1Z1D B;  3DKX A;  4ZQ9 A;  3QK2 A;  1RZ9 A;  1TBD A;  3QFQ A;  2NTC A;  2IF9 A; 
#chains in the Genus database with same CATH homology
 2FUF A;  4GDF A;  5CYN A;  3DKY A;  4FB3 A;  4LMD A;  5BYG A;  2ITJ A;  1M55 A;  1L5I A;  4ZO0 A;  2IPR A;  4U87 A;  2TBD A;  4KW3 A;  1R9W A;  1KSX A;  1UUT A;  1L2M A;  3QN2 A;  5D9I A;  4FGN A;  2NL8 A;  2HW0 A;  4LIF A;  4NBP A;  5DCX A;  1KSY A;  1F08 A;  2ITL A;  1Z1D B;  3DKX A;  4ZQ9 A;  3QK2 A;  1RZ9 A;  1TBD A;  3QFQ A;  2NTC A;  2IF9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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