2IQ1A

Crystal structure of human ppm1k
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
260
structure length
257
Chain Sequence
ISLENVGCASQIGKRKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural genomics of protein phosphatases
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein phosphatase 2C kappa, PPM1K
total genus 87
structure length 257
sequence length 260
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2006-10-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00481 PP2C Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2iq1A00
3W42A 4LGBB 3F79A 3W40A 2POPA 3ZT9A 2IRMA 3N3CA 3KB3B 3RNRA 4RA2A 3FXJA 3KDJB 2CM1A 4OICB 3JRQA 3NMNB 4YZGA 3W41A 3ZVUB 3FXMA 3W43A 2PK0A 2JFSA 3RT0A 3W45A 3FXLA 2POMA 4YZHA 2XZVA 4DA1A 2ISNA 5ITIA 3QN1B 3NMVB 3UJGB 4LG5B 5F1MA 3EQ2A 3UJLB 4WVOB 2J86A 4RAFA 5JO1B 2PNQA 3FXOA 4LA7B 4N0GA 3W44A 2JFTA 3T91A 3PU9A 2J4OA 5JO2B 2P8EA 3T9QA 2IQ1A 4RAGA 2JFRA 2V06A 3ES2A 3FXKA 3D8KA 4JNDA 1TXOA 4DS8B 3UJKA 3KE6A 5D2UA 2I44A 1A6QA 3MQ3A 2I0OA 2Y09A 3NMTB 4LGAB 2J82A
chains in the Genus database with same CATH superfamily
3W42A 4LGBB 3F79A 3W40A 2POPA 3ZT9A 2IRMA 3N3CA 3KB3B 3RNRA 4RA2A 3FXJA 3KDJB 2CM1A 4OICB 3JRQA 3NMNB 4YZGA 3W41A 3ZVUB 3FXMA 3W43A 2PK0A 2JFSA 3RT0A 3W45A 4IIKA 3FXLA 2POMA 4YZHA 2XZVA 4DA1A 2ISNA 5ITIA 4IIPA 3QN1B 3NMVB 3UJGB 4LG5B 5F1MA 3EQ2A 3UJLB 4WVOB 2J86A 4RAFA 2PNQA 5JO1B 3FXOA 4LA7B 4N0GA 3W44A 2JFTA 3T91A 3PU9A 2J4OA 5JO2B 2P8EA 3T9QA 2IQ1A 4RAGA 2JFRA 2V06A 3ES2A 3FXKA 3D8KA 4JNDA 1TXOA 4DS8B 3UJKA 3KE6A 5D2UA 2I44A 1A6QA 3MQ3A 2I0OA 2Y09A 3NMTB 4LGAB 2J82A
chains in the Genus database with same CATH topology
3W42A 4LGBB 3F79A 3W40A 2POPA 3ZT9A 2IRMA 3N3CA 3KB3B 3RNRA 4RA2A 3FXJA 3KDJB 2CM1A 4OICB 3JRQA 3NMNB 4YZGA 3W41A 3ZVUB 3FXMA 3W43A 2PK0A 2JFSA 3RT0A 3W45A 3FXLA 2POMA 4YZHA 2XZVA 4DA1A 2ISNA 5ITIA 3QN1B 3NMVB 3UJGB 4LG5B 5F1MA 3EQ2A 3UJLB 4WVOB 2J86A 4RAFA 5JO1B 2PNQA 3FXOA 4LA7B 4N0GA 3W44A 2JFTA 3T91A 3PU9A 2J4OA 5JO2B 2P8EA 3T9QA 2IQ1A 4RAGA 2JFRA 2V06A 3ES2A 3FXKA 3D8KA 4JNDA 1TXOA 4DS8B 3UJKA 3KE6A 5D2UA 2I44A 1A6QA 3MQ3A 2I0OA 2Y09A 3NMTB 4LGAB 2J82A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W42 A;  4LGB B;  3F79 A;  3W40 A;  2POP A;  3ZT9 A;  2IRM A;  3N3C A;  3KB3 B;  3RNR A;  4RA2 A;  3FXJ A;  3KDJ B;  2CM1 A;  4OIC B;  3JRQ A;  3NMN B;  4YZG A;  3W41 A;  3ZVU B;  3FXM A;  3W43 A;  2PK0 A;  2JFS A;  3RT0 A;  3W45 A;  3FXL A;  2POM A;  4YZH A;  2XZV A;  4DA1 A;  2ISN A;  5ITI A;  3QN1 B;  3NMV B;  3UJG B;  4LG5 B;  5F1M A;  3EQ2 A;  3UJL B;  4WVO B;  2J86 A;  4RAF A;  5JO1 B;  2PNQ A;  3FXO A;  4LA7 B;  4N0G A;  3W44 A;  2JFT A;  3T91 A;  3PU9 A;  2J4O A;  5JO2 B;  2P8E A;  3T9Q A;  2IQ1 A;  4RAG A;  2JFR A;  2V06 A;  3ES2 A;  3FXK A;  3D8K A;  4JND A;  1TXO A;  4DS8 B;  3UJK A;  3KE6 A;  5D2U A;  2I44 A;  1A6Q A;  3MQ3 A;  2I0O A;  2Y09 A;  3NMT B;  4LGA B;  2J82 A; 
#chains in the Genus database with same CATH topology
 3W42 A;  4LGB B;  3F79 A;  3W40 A;  2POP A;  3ZT9 A;  2IRM A;  3N3C A;  3KB3 B;  3RNR A;  4RA2 A;  3FXJ A;  3KDJ B;  2CM1 A;  4OIC B;  3JRQ A;  3NMN B;  4YZG A;  3W41 A;  3ZVU B;  3FXM A;  3W43 A;  2PK0 A;  2JFS A;  3RT0 A;  3W45 A;  4IIK A;  3FXL A;  2POM A;  4YZH A;  2XZV A;  4DA1 A;  2ISN A;  5ITI A;  4IIP A;  3QN1 B;  3NMV B;  3UJG B;  4LG5 B;  5F1M A;  3EQ2 A;  3UJL B;  4WVO B;  2J86 A;  4RAF A;  2PNQ A;  5JO1 B;  3FXO A;  4LA7 B;  4N0G A;  3W44 A;  2JFT A;  3T91 A;  3PU9 A;  2J4O A;  5JO2 B;  2P8E A;  3T9Q A;  2IQ1 A;  4RAG A;  2JFR A;  2V06 A;  3ES2 A;  3FXK A;  3D8K A;  4JND A;  1TXO A;  4DS8 B;  3UJK A;  3KE6 A;  5D2U A;  2I44 A;  1A6Q A;  3MQ3 A;  2I0O A;  2Y09 A;  3NMT B;  4LGA B;  2J82 A; 
#chains in the Genus database with same CATH homology
 3W42 A;  4LGB B;  3F79 A;  3W40 A;  2POP A;  3ZT9 A;  2IRM A;  3N3C A;  3KB3 B;  3RNR A;  4RA2 A;  3FXJ A;  3KDJ B;  2CM1 A;  4OIC B;  3JRQ A;  3NMN B;  4YZG A;  3W41 A;  3ZVU B;  3FXM A;  3W43 A;  2PK0 A;  2JFS A;  3RT0 A;  3W45 A;  3FXL A;  2POM A;  4YZH A;  2XZV A;  4DA1 A;  2ISN A;  5ITI A;  3QN1 B;  3NMV B;  3UJG B;  4LG5 B;  5F1M A;  3EQ2 A;  3UJL B;  4WVO B;  2J86 A;  4RAF A;  5JO1 B;  2PNQ A;  3FXO A;  4LA7 B;  4N0G A;  3W44 A;  2JFT A;  3T91 A;  3PU9 A;  2J4O A;  5JO2 B;  2P8E A;  3T9Q A;  2IQ1 A;  4RAG A;  2JFR A;  2V06 A;  3ES2 A;  3FXK A;  3D8K A;  4JND A;  1TXO A;  4DS8 B;  3UJK A;  3KE6 A;  5D2U A;  2I44 A;  1A6Q A;  3MQ3 A;  2I0O A;  2Y09 A;  3NMT B;  4LGA B;  2J82 A; 
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