2ISNA

Crystal structure of a phosphatase from a pathogenic strain toxoplasma gondii
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
345
structure length
331
Chain Sequence
KKVITVNEWYTTTVAATMLGRRPTDEDAILVSAPPNVRIKAVFDGHAGEATSQYCAKHAAKHLGKLSEFTFAEVKKACLSLDAEIIRKLGPKHVAGSTGIIVAIERLSAPVVENVVGREIVPRFVPLEKLIQEEEEAVGRYPRVPDVQQKTIPAGSFLVTAINIGDSRATLIHSDGGLTRLSKDHKPNHPTEASRIEKAGGSVETFDVPRVDGVLALSRAFGDSDFKMNPNLPPEEQKVIAVPDVRQFYALSSDLLLLACDGVYEPSGMDWAYVRDLTVAEMQRSKGDLEEVAARVMDYAYDMNSQDNISVMLVAFHNQEVEHPTAVYKVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Toxoplasma gondii
molecule keywords NYSGXRC-8828z, phosphatase
total genus 85
structure length 331
sequence length 345
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-10-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2isnA00
4LA7B 3ZVUB 3EQ2A 4RA2A 5JO1B 3NMTB 3FXLA 3T91A 2I44A 2J82A 3T9QA 4LGBB 3FXKA 4LG5B 3MQ3A 3W45A 3KB3B 3F79A 3KE6A 3W40A 2V06A 3UJLB 3ZT9A 3W43A 2POPA 2XZVA 2JFRA 3FXOA 3UJGB 3UJKA 1A6QA 2I0OA 2CM1A 3JRQA 2P8EA 3QN1B 2POMA 2IQ1A 4YZGA 5D2UA 4JNDA 3FXMA 3ES2A 4OICB 2J86A 4RAFA 4YZHA 4DS8B 3W41A 2Y09A 3FXJA 3W42A 3NMNB 2JFSA 4DA1A 5JO2B 3KDJB 2JFTA 3RT0A 2PK0A 3D8KA 3NMVB 3RNRA 3W44A 4LGAB 1TXOA 2J4OA 3N3CA 4N0GA 2PNQA 3PU9A 4WVOB 5ITIA 5F1MA 4RAGA 2ISNA 2IRMA
chains in the Genus database with same CATH superfamily
4LA7B 4IIPA 3ZVUB 3EQ2A 4RA2A 5JO1B 3NMTB 3FXLA 3T91A 2I44A 2J82A 3T9QA 4LGBB 3FXKA 4LG5B 3MQ3A 3W45A 3KB3B 3F79A 3KE6A 3W40A 2V06A 3UJLB 3ZT9A 3W43A 2POPA 2XZVA 2JFRA 3FXOA 3UJGB 3UJKA 1A6QA 2I0OA 2CM1A 3JRQA 2P8EA 3QN1B 2POMA 2IQ1A 4YZGA 5D2UA 4JNDA 3FXMA 3ES2A 4OICB 2J86A 4RAFA 4YZHA 4DS8B 3W41A 2Y09A 3FXJA 4IIKA 3W42A 3NMNB 2JFSA 4DA1A 5JO2B 3KDJB 2JFTA 3RT0A 2PK0A 3D8KA 3NMVB 3RNRA 3W44A 4LGAB 1TXOA 2J4OA 3N3CA 4N0GA 2PNQA 3PU9A 4WVOB 5ITIA 5F1MA 4RAGA 2ISNA 2IRMA
chains in the Genus database with same CATH topology
4LA7B 3ZVUB 3EQ2A 4RA2A 5JO1B 3NMTB 3FXLA 3T91A 2I44A 2J82A 3T9QA 4LGBB 3FXKA 4LG5B 3MQ3A 3W45A 3KB3B 3F79A 3KE6A 3W40A 2V06A 3UJLB 3ZT9A 3W43A 2POPA 2XZVA 2JFRA 3FXOA 3UJGB 3UJKA 1A6QA 2I0OA 2CM1A 3JRQA 2P8EA 3QN1B 2POMA 2IQ1A 4YZGA 5D2UA 4JNDA 3FXMA 3ES2A 4OICB 2J86A 4RAFA 4YZHA 4DS8B 3W41A 2Y09A 3FXJA 3W42A 3NMNB 2JFSA 4DA1A 5JO2B 3KDJB 2JFTA 3RT0A 2PK0A 3D8KA 3NMVB 3RNRA 3W44A 4LGAB 1TXOA 2J4OA 3N3CA 4N0GA 2PNQA 3PU9A 4WVOB 5ITIA 5F1MA 4RAGA 2ISNA 2IRMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LA7 B;  3ZVU B;  3EQ2 A;  4RA2 A;  5JO1 B;  3NMT B;  3FXL A;  3T91 A;  2I44 A;  2J82 A;  3T9Q A;  4LGB B;  3FXK A;  4LG5 B;  3MQ3 A;  3W45 A;  3KB3 B;  3F79 A;  3KE6 A;  3W40 A;  2V06 A;  3UJL B;  3ZT9 A;  3W43 A;  2POP A;  2XZV A;  2JFR A;  3FXO A;  3UJG B;  3UJK A;  1A6Q A;  2I0O A;  2CM1 A;  3JRQ A;  2P8E A;  3QN1 B;  2POM A;  2IQ1 A;  4YZG A;  5D2U A;  4JND A;  3FXM A;  3ES2 A;  4OIC B;  2J86 A;  4RAF A;  4YZH A;  4DS8 B;  3W41 A;  2Y09 A;  3FXJ A;  3W42 A;  3NMN B;  2JFS A;  4DA1 A;  5JO2 B;  3KDJ B;  2JFT A;  3RT0 A;  2PK0 A;  3D8K A;  3NMV B;  3RNR A;  3W44 A;  4LGA B;  1TXO A;  2J4O A;  3N3C A;  4N0G A;  2PNQ A;  3PU9 A;  4WVO B;  5ITI A;  5F1M A;  4RAG A;  2ISN A;  2IRM A; 
#chains in the Genus database with same CATH topology
 4LA7 B;  4IIP A;  3ZVU B;  3EQ2 A;  4RA2 A;  5JO1 B;  3NMT B;  3FXL A;  3T91 A;  2I44 A;  2J82 A;  3T9Q A;  4LGB B;  3FXK A;  4LG5 B;  3MQ3 A;  3W45 A;  3KB3 B;  3F79 A;  3KE6 A;  3W40 A;  2V06 A;  3UJL B;  3ZT9 A;  3W43 A;  2POP A;  2XZV A;  2JFR A;  3FXO A;  3UJG B;  3UJK A;  1A6Q A;  2I0O A;  2CM1 A;  3JRQ A;  2P8E A;  3QN1 B;  2POM A;  2IQ1 A;  4YZG A;  5D2U A;  4JND A;  3FXM A;  3ES2 A;  4OIC B;  2J86 A;  4RAF A;  4YZH A;  4DS8 B;  3W41 A;  2Y09 A;  3FXJ A;  4IIK A;  3W42 A;  3NMN B;  2JFS A;  4DA1 A;  5JO2 B;  3KDJ B;  2JFT A;  3RT0 A;  2PK0 A;  3D8K A;  3NMV B;  3RNR A;  3W44 A;  4LGA B;  1TXO A;  2J4O A;  3N3C A;  4N0G A;  2PNQ A;  3PU9 A;  4WVO B;  5ITI A;  5F1M A;  4RAG A;  2ISN A;  2IRM A; 
#chains in the Genus database with same CATH homology
 4LA7 B;  3ZVU B;  3EQ2 A;  4RA2 A;  5JO1 B;  3NMT B;  3FXL A;  3T91 A;  2I44 A;  2J82 A;  3T9Q A;  4LGB B;  3FXK A;  4LG5 B;  3MQ3 A;  3W45 A;  3KB3 B;  3F79 A;  3KE6 A;  3W40 A;  2V06 A;  3UJL B;  3ZT9 A;  3W43 A;  2POP A;  2XZV A;  2JFR A;  3FXO A;  3UJG B;  3UJK A;  1A6Q A;  2I0O A;  2CM1 A;  3JRQ A;  2P8E A;  3QN1 B;  2POM A;  2IQ1 A;  4YZG A;  5D2U A;  4JND A;  3FXM A;  3ES2 A;  4OIC B;  2J86 A;  4RAF A;  4YZH A;  4DS8 B;  3W41 A;  2Y09 A;  3FXJ A;  3W42 A;  3NMN B;  2JFS A;  4DA1 A;  5JO2 B;  3KDJ B;  2JFT A;  3RT0 A;  2PK0 A;  3D8K A;  3NMV B;  3RNR A;  3W44 A;  4LGA B;  1TXO A;  2J4O A;  3N3C A;  4N0G A;  2PNQ A;  3PU9 A;  4WVO B;  5ITI A;  5F1M A;  4RAG A;  2ISN A;  2IRM A; 
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similar chains in the Genus database (?% sequence similarity)
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