2ISNA

Crystal structure of a phosphatase from a pathogenic strain toxoplasma gondii
Total Genus 85
5010015020025030001020304050607080
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
345
structure length
331
Chain Sequence
KKVITVNEWYTTTVAATMLGRRPTDEDAILVSAPPNVRIKAVFDGHAGEATSQYCAKHAAKHLGKLSEFTFAEVKKACLSLDAEIIRKLGPKHVAGSTGIIVAIERLSAPVVENVVGREIVPRFVPLEKLIQEEEEAVGRYPRVPDVQQKTIPAGSFLVTAINIGDSRATLIHSDGGLTRLSKDHKPNHPTEASRIEKAGGSVETFDVPRVDGVLALSRAFGDSDFKMNPNLPPEEQKVIAVPDVRQFYALSSDLLLLACDGVYEPSGMDWAYVRDLTVAEMQRSKGDLEEVAARVMDYAYDMNSQDNISVMLVAFHNQEVEHPTAVYKVV

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS1 (4-10)TIV12 (316-320)TIV11 (315-318)3H6 (312-315)AH6 (305-311)S2 (13-18)TIV2 (36-43)3H5 (297-301)TII'2 (21-24)TI'1 (301-304)TIV1 (24-27)S5 (102-113)TVIII2 (96-99)S4 (43-52)TIV8 (221-224)AH2 (77-95)TIV3 (51-54)AH1 (55-70)S12 (219-221)S13 (225-227)S8 (164-168)TIV5 (97-100)AH3 (138-148)TIV6 (113-116)S6 (117-122)3H3 (250-252)S7 (125-126)TIV7 (121-124)S10 (184-188)S9 (172-180)TII1 (169-172)TI1 (189-192)S14 (237-238)TIV10 (246-249)TVIII4 (253-256)S15 (260-266)TI3 (267-270)S16 (271-275)3H4 (277-279)AH5 (287-296)TII'1 (10-13)TVIII1 (72-75)TIV9 (245-248)3H2 (240-242)AH4 (206-215)TI2 (202-205)S3 (29-32)S11 (194-196)Updating...
connected with : NaN
molecule tags Hydrolase
source organism Toxoplasma gondii
publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
molecule keywords NYSGXRC-8828z, phosphatase
total genus 85
structure length 331
sequence length 345
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-10-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2isnA00
4RAFA 2JFSA 3NMTB 3T9QA 1TXOA 2Y09A 5JO1B 3NMNB 3FXMA 4DA1A 3KE6A 2CM1A 2XZVA 2I0OA 4YZHA 2JFRA 5D2UA 3W45A 3ZVUB 3F79A 5ITIA 4LGBB 4LG5B 3RNRA 2J86A 4WVOB 3W43A 2J82A 2I44A 3UJKA 2P8EA 3MQ3A 3UJGB 3PU9A 3KDJB 3N3CA 4JNDA 4N0GA 3QN1B 2ISNA 3D8KA 4DS8B 4RAGA 4YZGA 3W41A 2JFTA 3W40A 3ZT9A 2POPA 3W42A 5F1MA 3FXKA 2POMA 3EQ2A 3RT0A 3JRQA 2PK0A 2J4OA 5JO2B 4LGAB 3FXJA 4OICB 4LA7B 2IQ1A 3NMVB 4RA2A 3ES2A 3FXOA 3UJLB 3FXLA 3W44A 2PNQA 2V06A 1A6QA 3KB3B 2IRMA 3T91A
chains in the Genus database with same CATH superfamily
4RAFA 2JFSA 3NMTB 3T9QA 1TXOA 2Y09A 5JO1B 3NMNB 3FXMA 4DA1A 4IIPA 3KE6A 2CM1A 2XZVA 2I0OA 4YZHA 2JFRA 5D2UA 3W45A 3ZVUB 3F79A 5ITIA 4LGBB 4LG5B 3RNRA 2J86A 4WVOB 3W43A 2J82A 2I44A 3UJKA 2P8EA 3MQ3A 3UJGB 3PU9A 3KDJB 3N3CA 4JNDA 4N0GA 3QN1B 2ISNA 3D8KA 4DS8B 4RAGA 4YZGA 3W41A 2JFTA 3W40A 3ZT9A 2POPA 3W42A 5F1MA 3FXKA 2POMA 4IIKA 3EQ2A 3RT0A 3JRQA 2PK0A 2J4OA 5JO2B 4LGAB 3FXJA 4OICB 4LA7B 2IQ1A 3NMVB 4RA2A 3ES2A 3FXOA 3UJLB 3FXLA 3W44A 2PNQA 2V06A 1A6QA 3KB3B 2IRMA 3T91A
chains in the Genus database with same CATH topology
4RAFA 2JFSA 3NMTB 3T9QA 1TXOA 2Y09A 5JO1B 3NMNB 3FXMA 4DA1A 3KE6A 2CM1A 2XZVA 2I0OA 4YZHA 2JFRA 5D2UA 3W45A 3ZVUB 3F79A 5ITIA 4LGBB 4LG5B 3RNRA 2J86A 4WVOB 3W43A 2J82A 2I44A 3UJKA 2P8EA 3MQ3A 3UJGB 3PU9A 3KDJB 3N3CA 4JNDA 4N0GA 3QN1B 2ISNA 3D8KA 4DS8B 4RAGA 4YZGA 3W41A 2JFTA 3W40A 3ZT9A 2POPA 3W42A 5F1MA 3FXKA 2POMA 3EQ2A 3RT0A 3JRQA 2PK0A 2J4OA 5JO2B 4LGAB 3FXJA 4OICB 4LA7B 2IQ1A 3NMVB 4RA2A 3ES2A 3FXOA 3UJLB 3FXLA 3W44A 2PNQA 2V06A 1A6QA 3KB3B 2IRMA 3T91A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RAF A;  2JFS A;  3NMT B;  3T9Q A;  1TXO A;  2Y09 A;  5JO1 B;  3NMN B;  3FXM A;  4DA1 A;  3KE6 A;  2CM1 A;  2XZV A;  2I0O A;  4YZH A;  2JFR A;  5D2U A;  3W45 A;  3ZVU B;  3F79 A;  5ITI A;  4LGB B;  4LG5 B;  3RNR A;  2J86 A;  4WVO B;  3W43 A;  2J82 A;  2I44 A;  3UJK A;  2P8E A;  3MQ3 A;  3UJG B;  3PU9 A;  3KDJ B;  3N3C A;  4JND A;  4N0G A;  3QN1 B;  2ISN A;  3D8K A;  4DS8 B;  4RAG A;  4YZG A;  3W41 A;  2JFT A;  3W40 A;  3ZT9 A;  2POP A;  3W42 A;  5F1M A;  3FXK A;  2POM A;  3EQ2 A;  3RT0 A;  3JRQ A;  2PK0 A;  2J4O A;  5JO2 B;  4LGA B;  3FXJ A;  4OIC B;  4LA7 B;  2IQ1 A;  3NMV B;  4RA2 A;  3ES2 A;  3FXO A;  3UJL B;  3FXL A;  3W44 A;  2PNQ A;  2V06 A;  1A6Q A;  3KB3 B;  2IRM A;  3T91 A; 
#chains in the Genus database with same CATH topology
 4RAF A;  2JFS A;  3NMT B;  3T9Q A;  1TXO A;  2Y09 A;  5JO1 B;  3NMN B;  3FXM A;  4DA1 A;  4IIP A;  3KE6 A;  2CM1 A;  2XZV A;  2I0O A;  4YZH A;  2JFR A;  5D2U A;  3W45 A;  3ZVU B;  3F79 A;  5ITI A;  4LGB B;  4LG5 B;  3RNR A;  2J86 A;  4WVO B;  3W43 A;  2J82 A;  2I44 A;  3UJK A;  2P8E A;  3MQ3 A;  3UJG B;  3PU9 A;  3KDJ B;  3N3C A;  4JND A;  4N0G A;  3QN1 B;  2ISN A;  3D8K A;  4DS8 B;  4RAG A;  4YZG A;  3W41 A;  2JFT A;  3W40 A;  3ZT9 A;  2POP A;  3W42 A;  5F1M A;  3FXK A;  2POM A;  4IIK A;  3EQ2 A;  3RT0 A;  3JRQ A;  2PK0 A;  2J4O A;  5JO2 B;  4LGA B;  3FXJ A;  4OIC B;  4LA7 B;  2IQ1 A;  3NMV B;  4RA2 A;  3ES2 A;  3FXO A;  3UJL B;  3FXL A;  3W44 A;  2PNQ A;  2V06 A;  1A6Q A;  3KB3 B;  2IRM A;  3T91 A; 
#chains in the Genus database with same CATH homology
 4RAF A;  2JFS A;  3NMT B;  3T9Q A;  1TXO A;  2Y09 A;  5JO1 B;  3NMN B;  3FXM A;  4DA1 A;  3KE6 A;  2CM1 A;  2XZV A;  2I0O A;  4YZH A;  2JFR A;  5D2U A;  3W45 A;  3ZVU B;  3F79 A;  5ITI A;  4LGB B;  4LG5 B;  3RNR A;  2J86 A;  4WVO B;  3W43 A;  2J82 A;  2I44 A;  3UJK A;  2P8E A;  3MQ3 A;  3UJG B;  3PU9 A;  3KDJ B;  3N3C A;  4JND A;  4N0G A;  3QN1 B;  2ISN A;  3D8K A;  4DS8 B;  4RAG A;  4YZG A;  3W41 A;  2JFT A;  3W40 A;  3ZT9 A;  2POP A;  3W42 A;  5F1M A;  3FXK A;  2POM A;  3EQ2 A;  3RT0 A;  3JRQ A;  2PK0 A;  2J4O A;  5JO2 B;  4LGA B;  3FXJ A;  4OIC B;  4LA7 B;  2IQ1 A;  3NMV B;  4RA2 A;  3ES2 A;  3FXO A;  3UJL B;  3FXL A;  3W44 A;  2PNQ A;  2V06 A;  1A6Q A;  3KB3 B;  2IRM A;  3T91 A; 
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