2ISNA

Crystal structure of a phosphatase from a pathogenic strain toxoplasma gondii
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
345
structure length
331
Chain Sequence
KKVITVNEWYTTTVAATMLGRRPTDEDAILVSAPPNVRIKAVFDGHAGEATSQYCAKHAAKHLGKLSEFTFAEVKKACLSLDAEIIRKLGPKHVAGSTGIIVAIERLSAPVVENVVGREIVPRFVPLEKLIQEEEEAVGRYPRVPDVQQKTIPAGSFLVTAINIGDSRATLIHSDGGLTRLSKDHKPNHPTEASRIEKAGGSVETFDVPRVDGVLALSRAFGDSDFKMNPNLPPEEQKVIAVPDVRQFYALSSDLLLLACDGVYEPSGMDWAYVRDLTVAEMQRSKGDLEEVAARVMDYAYDMNSQDNISVMLVAFHNQEVEHPTAVYKVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Toxoplasma gondii
publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
molecule keywords NYSGXRC-8828z, phosphatase
total genus 85
structure length 331
sequence length 345
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-10-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2isnA00
4DS8B 3FXOA 1A6QA 2J82A 3FXMA 3KE6A 3UJGB 4YZHA 2POPA 2V06A 3RT0A 3T9QA 5ITIA 5JO2B 5F1MA 2JFSA 4LGAB 3UJLB 3MQ3A 3ES2A 4LGBB 2XZVA 2PK0A 4LA7B 2IQ1A 3NMNB 2I0OA 3FXJA 3D8KA 3N3CA 4LG5B 4JNDA 2Y09A 1TXOA 3ZVUB 4OICB 3W42A 2P8EA 4DA1A 2PNQA 2JFTA 2I44A 2ISNA 3W41A 3KB3B 3W40A 3FXKA 4WVOB 4RA2A 3KDJB 5JO1B 2JFRA 3ZT9A 3W44A 5D2UA 3RNRA 2J86A 3QN1B 4YZGA 3FXLA 3W45A 2CM1A 4N0GA 3F79A 3UJKA 3T91A 2J4OA 3EQ2A 4RAFA 3JRQA 3NMVB 3PU9A 4RAGA 2POMA 3NMTB 3W43A 2IRMA
chains in the Genus database with same CATH superfamily
4DS8B 3FXOA 1A6QA 2J82A 3FXMA 3KE6A 3UJGB 4YZHA 2POPA 2V06A 3RT0A 3T9QA 5ITIA 5JO2B 5F1MA 2JFSA 4LGAB 3UJLB 3MQ3A 3ES2A 4LGBB 2XZVA 2PK0A 4LA7B 2IQ1A 3NMNB 4IIKA 2I0OA 3FXJA 3D8KA 3N3CA 4LG5B 4JNDA 2Y09A 1TXOA 3ZVUB 4OICB 3W42A 2P8EA 4DA1A 2PNQA 2JFTA 2I44A 2ISNA 3W41A 3KB3B 3W40A 3FXKA 4WVOB 4RA2A 3KDJB 5JO1B 2JFRA 3ZT9A 3W44A 5D2UA 3RNRA 2J86A 3QN1B 4YZGA 3FXLA 3W45A 2CM1A 4IIPA 4N0GA 3F79A 3UJKA 3T91A 2J4OA 3EQ2A 4RAFA 3JRQA 3NMVB 3PU9A 4RAGA 2POMA 3NMTB 3W43A 2IRMA
chains in the Genus database with same CATH topology
4DS8B 3FXOA 1A6QA 2J82A 3FXMA 3KE6A 3UJGB 4YZHA 2POPA 2V06A 3RT0A 3T9QA 5ITIA 5JO2B 5F1MA 2JFSA 4LGAB 3UJLB 3MQ3A 3ES2A 4LGBB 2XZVA 2PK0A 4LA7B 2IQ1A 3NMNB 2I0OA 3FXJA 3D8KA 3N3CA 4LG5B 4JNDA 2Y09A 1TXOA 3ZVUB 4OICB 3W42A 2P8EA 4DA1A 2PNQA 2JFTA 2I44A 2ISNA 3W41A 3KB3B 3W40A 3FXKA 4WVOB 4RA2A 3KDJB 5JO1B 2JFRA 3ZT9A 3W44A 5D2UA 3RNRA 2J86A 3QN1B 4YZGA 3FXLA 3W45A 2CM1A 4N0GA 3F79A 3UJKA 3T91A 2J4OA 3EQ2A 4RAFA 3JRQA 3NMVB 3PU9A 4RAGA 2POMA 3NMTB 3W43A 2IRMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DS8 B;  3FXO A;  1A6Q A;  2J82 A;  3FXM A;  3KE6 A;  3UJG B;  4YZH A;  2POP A;  2V06 A;  3RT0 A;  3T9Q A;  5ITI A;  5JO2 B;  5F1M A;  2JFS A;  4LGA B;  3UJL B;  3MQ3 A;  3ES2 A;  4LGB B;  2XZV A;  2PK0 A;  4LA7 B;  2IQ1 A;  3NMN B;  2I0O A;  3FXJ A;  3D8K A;  3N3C A;  4LG5 B;  4JND A;  2Y09 A;  1TXO A;  3ZVU B;  4OIC B;  3W42 A;  2P8E A;  4DA1 A;  2PNQ A;  2JFT A;  2I44 A;  2ISN A;  3W41 A;  3KB3 B;  3W40 A;  3FXK A;  4WVO B;  4RA2 A;  3KDJ B;  5JO1 B;  2JFR A;  3ZT9 A;  3W44 A;  5D2U A;  3RNR A;  2J86 A;  3QN1 B;  4YZG A;  3FXL A;  3W45 A;  2CM1 A;  4N0G A;  3F79 A;  3UJK A;  3T91 A;  2J4O A;  3EQ2 A;  4RAF A;  3JRQ A;  3NMV B;  3PU9 A;  4RAG A;  2POM A;  3NMT B;  3W43 A;  2IRM A; 
#chains in the Genus database with same CATH topology
 4DS8 B;  3FXO A;  1A6Q A;  2J82 A;  3FXM A;  3KE6 A;  3UJG B;  4YZH A;  2POP A;  2V06 A;  3RT0 A;  3T9Q A;  5ITI A;  5JO2 B;  5F1M A;  2JFS A;  4LGA B;  3UJL B;  3MQ3 A;  3ES2 A;  4LGB B;  2XZV A;  2PK0 A;  4LA7 B;  2IQ1 A;  3NMN B;  4IIK A;  2I0O A;  3FXJ A;  3D8K A;  3N3C A;  4LG5 B;  4JND A;  2Y09 A;  1TXO A;  3ZVU B;  4OIC B;  3W42 A;  2P8E A;  4DA1 A;  2PNQ A;  2JFT A;  2I44 A;  2ISN A;  3W41 A;  3KB3 B;  3W40 A;  3FXK A;  4WVO B;  4RA2 A;  3KDJ B;  5JO1 B;  2JFR A;  3ZT9 A;  3W44 A;  5D2U A;  3RNR A;  2J86 A;  3QN1 B;  4YZG A;  3FXL A;  3W45 A;  2CM1 A;  4IIP A;  4N0G A;  3F79 A;  3UJK A;  3T91 A;  2J4O A;  3EQ2 A;  4RAF A;  3JRQ A;  3NMV B;  3PU9 A;  4RAG A;  2POM A;  3NMT B;  3W43 A;  2IRM A; 
#chains in the Genus database with same CATH homology
 4DS8 B;  3FXO A;  1A6Q A;  2J82 A;  3FXM A;  3KE6 A;  3UJG B;  4YZH A;  2POP A;  2V06 A;  3RT0 A;  3T9Q A;  5ITI A;  5JO2 B;  5F1M A;  2JFS A;  4LGA B;  3UJL B;  3MQ3 A;  3ES2 A;  4LGB B;  2XZV A;  2PK0 A;  4LA7 B;  2IQ1 A;  3NMN B;  2I0O A;  3FXJ A;  3D8K A;  3N3C A;  4LG5 B;  4JND A;  2Y09 A;  1TXO A;  3ZVU B;  4OIC B;  3W42 A;  2P8E A;  4DA1 A;  2PNQ A;  2JFT A;  2I44 A;  2ISN A;  3W41 A;  3KB3 B;  3W40 A;  3FXK A;  4WVO B;  4RA2 A;  3KDJ B;  5JO1 B;  2JFR A;  3ZT9 A;  3W44 A;  5D2U A;  3RNR A;  2J86 A;  3QN1 B;  4YZG A;  3FXL A;  3W45 A;  2CM1 A;  4N0G A;  3F79 A;  3UJK A;  3T91 A;  2J4O A;  3EQ2 A;  4RAF A;  3JRQ A;  3NMV B;  3PU9 A;  4RAG A;  2POM A;  3NMT B;  3W43 A;  2IRM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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