2ITJA

Origin binding domain of the sv40 large t antigen (residues 131-259). p212121 crystal form
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
128
structure length
128
Chain Sequence
VEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
pubmed doi rcsb
molecule tags Dna binding protein
source organism Simian virus 40
molecule keywords large T antigen
total genus 31
structure length 128
sequence length 128
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 2itjA00
2TBDA 1M55A 1UUTA 4FB3A 4LIFA 4FGNA 5CYNA 3QFQA 4NBPA 5DCXA 2NL8A 4LMDA 1Z1DB 2IPRA 1TBDA 3QK2A 2ITJA 4GDFA 1RZ9A 4ZQ9A 2NTCA 2FUFA 2IF9A 3QN2A 1L2MA 2HW0A 5D9IA 5BYGA 4ZO0A 1L5IA 2ITLA
chains in the Genus database with same CATH superfamily
4U87A 1KSXA 2TBDA 1M55A 1UUTA 4FB3A 4LIFA 4FGNA 5CYNA 3QFQA 1R9WA 4NBPA 5DCXA 2NL8A 4LMDA 1F08A 1Z1DB 2IPRA 1TBDA 3QK2A 2ITJA 4KW3A 1KSYA 4GDFA 3DKYA 3DKXA 1RZ9A 4ZQ9A 2NTCA 2FUFA 2IF9A 3QN2A 1L2MA 2HW0A 5D9IA 5BYGA 4ZO0A 1L5IA 2ITLA
chains in the Genus database with same CATH topology
4U87A 1KSXA 2TBDA 1M55A 1UUTA 4FB3A 4LIFA 4FGNA 5CYNA 3QFQA 1R9WA 4NBPA 5DCXA 2NL8A 4LMDA 1F08A 1Z1DB 2IPRA 1TBDA 3QK2A 2ITJA 4KW3A 1KSYA 4GDFA 3DKYA 3DKXA 1RZ9A 4ZQ9A 2NTCA 2FUFA 2IF9A 3QN2A 1L2MA 2HW0A 5D9IA 5BYGA 4ZO0A 1L5IA 2ITLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2TBD A;  1M55 A;  1UUT A;  4FB3 A;  4LIF A;  4FGN A;  5CYN A;  3QFQ A;  4NBP A;  5DCX A;  2NL8 A;  4LMD A;  1Z1D B;  2IPR A;  1TBD A;  3QK2 A;  2ITJ A;  4GDF A;  1RZ9 A;  4ZQ9 A;  2NTC A;  2FUF A;  2IF9 A;  3QN2 A;  1L2M A;  2HW0 A;  5D9I A;  5BYG A;  4ZO0 A;  1L5I A;  2ITL A; 
#chains in the Genus database with same CATH topology
 4U87 A;  1KSX A;  2TBD A;  1M55 A;  1UUT A;  4FB3 A;  4LIF A;  4FGN A;  5CYN A;  3QFQ A;  1R9W A;  4NBP A;  5DCX A;  2NL8 A;  4LMD A;  1F08 A;  1Z1D B;  2IPR A;  1TBD A;  3QK2 A;  2ITJ A;  4KW3 A;  1KSY A;  4GDF A;  3DKY A;  3DKX A;  1RZ9 A;  4ZQ9 A;  2NTC A;  2FUF A;  2IF9 A;  3QN2 A;  1L2M A;  2HW0 A;  5D9I A;  5BYG A;  4ZO0 A;  1L5I A;  2ITL A; 
#chains in the Genus database with same CATH homology
 4U87 A;  1KSX A;  2TBD A;  1M55 A;  1UUT A;  4FB3 A;  4LIF A;  4FGN A;  5CYN A;  3QFQ A;  1R9W A;  4NBP A;  5DCX A;  2NL8 A;  4LMD A;  1F08 A;  1Z1D B;  2IPR A;  1TBD A;  3QK2 A;  2ITJ A;  4KW3 A;  1KSY A;  4GDF A;  3DKY A;  3DKX A;  1RZ9 A;  4ZQ9 A;  2NTC A;  2FUF A;  2IF9 A;  3QN2 A;  1L2M A;  2HW0 A;  5D9I A;  5BYG A;  4ZO0 A;  1L5I A;  2ITL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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