2ITLA

The origin binding domain of the sv40 large t antigen bound to the functional pen palindrome dna (23 bp)
Total Genus 33
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
120
structure length
120
Chain Sequence
DPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
pubmed doi rcsb
molecule keywords 24-nt PEN element of the SV40 DNA origin
molecule tags Dna binding protein/dna
source organism Simian virus 40
total genus 33
structure length 120
sequence length 120
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 2itlA00
1L5IA 5CYNA 2NTCA 4NBPA 2NL8A 2TBDA 5D9IA 3QFQA 2FUFA 1RZ9A 2HW0A 2IF9A 4ZQ9A 4LIFA 3QK2A 5BYGA 1Z1DB 2ITLA 4FB3A 2ITJA 2IPRA 5DCXA 1UUTA 1M55A 1TBDA 3QN2A 4FGNA 4GDFA 1L2MA 4LMDA 4ZO0A
chains in the Genus database with same CATH superfamily
1L5IA 5CYNA 2NTCA 4NBPA 2NL8A 2TBDA 5D9IA 3QFQA 2FUFA 1RZ9A 2HW0A 2IF9A 4U87A 4ZQ9A 4KW3A 4LIFA 3QK2A 5BYGA 1Z1DB 1F08A 1KSXA 2ITLA 4FB3A 1R9WA 2ITJA 2IPRA 1KSYA 5DCXA 1UUTA 1M55A 3DKXA 1TBDA 3QN2A 4FGNA 4GDFA 3DKYA 1L2MA 4LMDA 4ZO0A
chains in the Genus database with same CATH topology
1L5IA 5CYNA 2NTCA 4NBPA 2NL8A 2TBDA 5D9IA 3QFQA 2FUFA 1RZ9A 2HW0A 2IF9A 4U87A 4ZQ9A 4KW3A 4LIFA 3QK2A 5BYGA 1Z1DB 1F08A 1KSXA 2ITLA 4FB3A 1R9WA 2ITJA 2IPRA 1KSYA 5DCXA 1UUTA 1M55A 3DKXA 1TBDA 3QN2A 4FGNA 4GDFA 3DKYA 1L2MA 4LMDA 4ZO0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L5I A;  5CYN A;  2NTC A;  4NBP A;  2NL8 A;  2TBD A;  5D9I A;  3QFQ A;  2FUF A;  1RZ9 A;  2HW0 A;  2IF9 A;  4ZQ9 A;  4LIF A;  3QK2 A;  5BYG A;  1Z1D B;  2ITL A;  4FB3 A;  2ITJ A;  2IPR A;  5DCX A;  1UUT A;  1M55 A;  1TBD A;  3QN2 A;  4FGN A;  4GDF A;  1L2M A;  4LMD A;  4ZO0 A; 
#chains in the Genus database with same CATH topology
 1L5I A;  5CYN A;  2NTC A;  4NBP A;  2NL8 A;  2TBD A;  5D9I A;  3QFQ A;  2FUF A;  1RZ9 A;  2HW0 A;  2IF9 A;  4U87 A;  4ZQ9 A;  4KW3 A;  4LIF A;  3QK2 A;  5BYG A;  1Z1D B;  1F08 A;  1KSX A;  2ITL A;  4FB3 A;  1R9W A;  2ITJ A;  2IPR A;  1KSY A;  5DCX A;  1UUT A;  1M55 A;  3DKX A;  1TBD A;  3QN2 A;  4FGN A;  4GDF A;  3DKY A;  1L2M A;  4LMD A;  4ZO0 A; 
#chains in the Genus database with same CATH homology
 1L5I A;  5CYN A;  2NTC A;  4NBP A;  2NL8 A;  2TBD A;  5D9I A;  3QFQ A;  2FUF A;  1RZ9 A;  2HW0 A;  2IF9 A;  4U87 A;  4ZQ9 A;  4KW3 A;  4LIF A;  3QK2 A;  5BYG A;  1Z1D B;  1F08 A;  1KSX A;  2ITL A;  4FB3 A;  1R9W A;  2ITJ A;  2IPR A;  1KSY A;  5DCX A;  1UUT A;  1M55 A;  3DKX A;  1TBD A;  3QN2 A;  4FGN A;  4GDF A;  3DKY A;  1L2M A;  4LMD A;  4ZO0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...