2J4O | Genus

Total Genus 114

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	114
sequence length	355
structure length	355
Chain Sequence	SWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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Time for openFile(/file/5cfd3bfe712f60aed1d2e8b4/pdb.gz): 1489 ms

reading 355 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

355 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 52 ms

Adding embedded #jmolscript: select ({0:354});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein binding
source organism	Homo sapiens
publication title	Tak1-Binding Protein 1 is a Pseudophosphatase. pubmed doi rcsb
molecule keywords	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING
total genus	114
structure length	355
sequence length	355
ec nomenclature
pdb deposition date	2006-09-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00481	PP2C	Protein phosphatase 2C

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.60.40.10	Alpha Beta	4-Layer Sandwich	Phosphatase 2c; domain 1	PPM-type phosphatase domain	2j4oA00

4DA1A 2ISNA 3FXKA 2J86A 3FXMA 3W40A 5ITIA 4YZGA 2POPA 4YZHA 3T91A 4LGAB 3RNRA 3MQ3A 2Y09A 3JRQA 2P8EA 3ZVUB 3W45A 4LGBB 2XZVA 4LG5B 3W42A 2JFTA 4JNDA 2J82A 3D8KA 2JFRA 3RT0A 2I0OA 2PK0A 4WVOB 3ES2A 3NMNB 3ZT9A 2I44A 3W43A 3KDJB 2POMA 4N0GA 3FXLA 3UJLB 4RA2A 3KB3B 5D2UA 3NMTB 4OICB 1TXOA 4RAGA 1A6QA 4LA7B 2IQ1A 2J4OA 2CM1A 3PU9A 2PNQA 3F79A 3T9QA 2V06A 3UJKA 3FXJA 3N3CA 3UJGB 3NMVB 3W41A 5F1MA 3W44A 3QN1B 5JO1B 4RAFA 4DS8B 3EQ2A 2IRMA 2JFSA 3FXOA 3KE6A 5JO2B
chains in the Genus database with same CATH superfamily

4DA1A 2ISNA 3FXKA 2J86A 3FXMA 3W40A 5ITIA 4YZGA 2POPA 4YZHA 3T91A 4LGAB 3RNRA 3MQ3A 2Y09A 3JRQA 2P8EA 3ZVUB 3W45A 4LGBB 2XZVA 4LG5B 3W42A 2JFTA 4JNDA 2J82A 3D8KA 2JFRA 3RT0A 2I0OA 2PK0A 4WVOB 3ES2A 3NMNB 3ZT9A 2I44A 3W43A 3KDJB 4IIKA 2POMA 4N0GA 3FXLA 3UJLB 4RA2A 3KB3B 5D2UA 3NMTB 4OICB 1TXOA 4RAGA 1A6QA 4LA7B 2IQ1A 2J4OA 2CM1A 3PU9A 2PNQA 3F79A 3T9QA 2V06A 3UJKA 3FXJA 3N3CA 3UJGB 4IIPA 3NMVB 3W41A 5F1MA 3W44A 3QN1B 5JO1B 4RAFA 4DS8B 3EQ2A 2IRMA 2JFSA 3FXOA 3KE6A 5JO2B
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4DA1 A;  2ISN A;  3FXK A;  2J86 A;  3FXM A;  3W40 A;  5ITI A;  4YZG A;  2POP A;  4YZH A;  3T91 A;  4LGA B;  3RNR A;  3MQ3 A;  2Y09 A;  3JRQ A;  2P8E A;  3ZVU B;  3W45 A;  4LGB B;  2XZV A;  4LG5 B;  3W42 A;  2JFT A;  4JND A;  2J82 A;  3D8K A;  2JFR A;  3RT0 A;  2I0O A;  2PK0 A;  4WVO B;  3ES2 A;  3NMN B;  3ZT9 A;  2I44 A;  3W43 A;  3KDJ B;  2POM A;  4N0G A;  3FXL A;  3UJL B;  4RA2 A;  3KB3 B;  5D2U A;  3NMT B;  4OIC B;  1TXO A;  4RAG A;  1A6Q A;  4LA7 B;  2IQ1 A;  2J4O A;  2CM1 A;  3PU9 A;  2PNQ A;  3F79 A;  3T9Q A;  2V06 A;  3UJK A;  3FXJ A;  3N3C A;  3UJG B;  3NMV B;  3W41 A;  5F1M A;  3W44 A;  3QN1 B;  5JO1 B;  4RAF A;  4DS8 B;  3EQ2 A;  2IRM A;  2JFS A;  3FXO A;  3KE6 A;  5JO2 B; 
#chains in the Genus database with same CATH topology
 4DA1 A;  2ISN A;  3FXK A;  2J86 A;  3FXM A;  3W40 A;  5ITI A;  4YZG A;  2POP A;  4YZH A;  3T91 A;  4LGA B;  3RNR A;  3MQ3 A;  2Y09 A;  3JRQ A;  2P8E A;  3ZVU B;  3W45 A;  4LGB B;  2XZV A;  4LG5 B;  3W42 A;  2JFT A;  4JND A;  2J82 A;  3D8K A;  2JFR A;  3RT0 A;  2I0O A;  2PK0 A;  4WVO B;  3ES2 A;  3NMN B;  3ZT9 A;  2I44 A;  3W43 A;  3KDJ B;  4IIK A;  2POM A;  4N0G A;  3FXL A;  3UJL B;  4RA2 A;  3KB3 B;  5D2U A;  3NMT B;  4OIC B;  1TXO A;  4RAG A;  1A6Q A;  4LA7 B;  2IQ1 A;  2J4O A;  2CM1 A;  3PU9 A;  2PNQ A;  3F79 A;  3T9Q A;  2V06 A;  3UJK A;  3FXJ A;  3N3C A;  3UJG B;  4IIP A;  3NMV B;  3W41 A;  5F1M A;  3W44 A;  3QN1 B;  5JO1 B;  4RAF A;  4DS8 B;  3EQ2 A;  2IRM A;  2JFS A;  3FXO A;  3KE6 A;  5JO2 B; 
#chains in the Genus database with same CATH homology
 4DA1 A;  2ISN A;  3FXK A;  2J86 A;  3FXM A;  3W40 A;  5ITI A;  4YZG A;  2POP A;  4YZH A;  3T91 A;  4LGA B;  3RNR A;  3MQ3 A;  2Y09 A;  3JRQ A;  2P8E A;  3ZVU B;  3W45 A;  4LGB B;  2XZV A;  4LG5 B;  3W42 A;  2JFT A;  4JND A;  2J82 A;  3D8K A;  2JFR A;  3RT0 A;  2I0O A;  2PK0 A;  4WVO B;  3ES2 A;  3NMN B;  3ZT9 A;  2I44 A;  3W43 A;  3KDJ B;  2POM A;  4N0G A;  3FXL A;  3UJL B;  4RA2 A;  3KB3 B;  5D2U A;  3NMT B;  4OIC B;  1TXO A;  4RAG A;  1A6Q A;  4LA7 B;  2IQ1 A;  2J4O A;  2CM1 A;  3PU9 A;  2PNQ A;  3F79 A;  3T9Q A;  2V06 A;  3UJK A;  3FXJ A;  3N3C A;  3UJG B;  3NMV B;  3W41 A;  5F1M A;  3W44 A;  3QN1 B;  5JO1 B;  4RAF A;  4DS8 B;  3EQ2 A;  2IRM A;  2JFS A;  3FXO A;  3KE6 A;  5JO2 B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2J4OA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations