2JA7E

Cpd lesion containing rna polymerase ii elongation complex c
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
publication title Cpd Damage Recognition by Transcribing RNA Polymerase II.
pubmed doi rcsb
molecule keywords 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3'
total genus 47
structure length 214
sequence length 214
chains with identical sequence Q
ec nomenclature
pdb deposition date 2006-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 2ja7E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 2ja7E02
3GTJE 4A3BE 3S1QE 3RZOE 2WAQH 1EIKA 3S1ME 3S2HE 3PO2E 1TWAE 3FKIE 3HOYE 2JA7E 4A3KE 2VUME 3S14E 2Y0SH 3PO3E 1TWHE 5C44E 2JA6E 4X6AE 3GTGE 4BXXE 5IP7E 1Y1VE 1K83E 4A3LE 4C2ME 4C3HE 3GTPE 2NVXE 5IYDE 4A3IE 1SFOE 4BY1E 1DZFA 4AYBH 2R93E 1R9TE 5C4JE 1I50E 3HOWE 5IYBE 1I3QE 2YU9E 2NVQE 3GTKE 3HOZE 5IP9E 4C3JE 4BBSE 2NVYE 4A3JE 2E2IE 2WB1H 2E2JE 5C3EE 5M3ME 5C4XE 3S17E 5IYCE 4A3CE 5M5WE 3M3YE 1TWCE 5FJ8E 5M3FE 4A3DE 4Y7NE 4QIWH 3K7AE 3RZDE 1WCME 1TWFE 2B63E 3S2DE 3S1NE 4A93E 3HOXE 3S16E 3H3VF 4Y52E 1Y1WE 5M5YE 3M4OE 2NVTE 4C3IE 3S1RE 3I4ME 2E2HE 3H0GE 3HKZH 2R7ZE 1TWGE 2JA5E 3GTOE 4A3EE 1I6HE 4A3FE 2PMZH 3GTME 3HOVE 4BBRE 3CQZE 4A3ME 2R92E 4BY7E 2JA8E 5M5XE 3S15E 4A3GE 3GTLE 3HOUE 3I4NE 5FLME 3GTQE
chains in the Genus database with same CATH superfamily
3GTJE 4A3BE 4A3BF 4A3IF 4BBSF 1SFOF 3S1QE 4BY1F 3RZOE 2WAQH 4XSXE 1IW7E 4G7OE 1EIKA 3S1ME 3S2HE 3S2HF 3PO2E 2R93F 2O5JE 1R9TF 3HOWF 2WAQK 1ZYRE 1TWAE 4ZH4E 1I3QF 5D4CE 3FKIE 3HOYE 3FKIF 4KN7E 2JA7E 2YU9F 3HOYF 4A3KE 2NVQF 3HOZF 4C3JF 4YFNE 2NVYF 2E2IF 5D4EE 2VUME 2VUMF 3S14E 1HQME 2A6HE 3PO3E 2Y0SH 3S14F 1TWHE 5C44E 3PO3F 2JA6E 4LLGE 4X6AE 3GTGE 3H3VG 4X6AF 2E2JF 4BXXE 5IP7E 5C3EF 5E17E 5M3MF 1Y1VE 1K83E 1K83F 4A3LE 1Y1VF 4C2ME 4C2MF 4C3HE 3GTPE 1QKLA 4OIRE 5IYCF 2NVXE 4YG2E 2NVXF 5IYDE 4A3IE 5IYDF 4A3CF 2A6EE 5D4DE 1SFOE 5M5WF 3M3YF 4BY1E 1DZFA 4XSZE 5M3FF 4AYBH 4XLNE 4Y7NF 2R93E 2Y0SI 4OINE 1R9TE 5C4JE 5C4JF 1I50E 3HOWE 1I50F 1TWFF 1WCMF 5IYBE 4LK1E 5IYBF 2B63F 1I3QE 2YU9E 4AYBK 4A93F 4Q4ZE 3HOXF 4Y52F 2NVQE 3GTKE 3HOZE 5IP9E 5IP9F 4C3JE 4BBSE 1Y1WF 2NVYE 4A3JE 2E2IE 5M5YF 4MQ9E 4A3JF 4MEXE 2WB1H 3GTMF 2NVTF 2O5IE 4C3IF 3S1RF 2E2JE 3H0GF 4LK0E 5C3EE 2E2HF 5M3ME 5C4XE 5C4XF 4MEYE 3S17E 3S17F 4LJZE 4Q5SE 5IYCE 4A3CE 2PPBE 5M5WE 3M3YE 1YNNK 1TWCE 1TWCF 2CW0E 4OIQE 4A3EF 5FJ8E 5TMFE 5FJ8F 1I6HF 4JK1E 3GTKF 5M3FE 4A3FF 5IPLE 4A3DE 3HOVF 4Y7NE 4XLPE 4G7HE 4BBRF 4A3DF 2WB1I 4QIWH 2A68E 3K7AE 3RZDE 3K7AF 1WCME 1TWFE 2B63E 3S2DE 3RZDF 2R92F 3S1NE 3S2DF 3S1NF 2JA8F 4A93E 3HOXE 3S16E 5M5XF 3H3VF 3S16F 4Y52E 4QIWK 4A3GF 1Y1WE 3GTLF 5M5YE 3HOUF 3I4NF 4OIOE 3M4OE 3M4OF 5FLMF 2NVTE 3GTQF 4C3IE 3S1RE 5TMCE 3I4ME 3GTJF 3I4MF 2E2HE 3H0GE 3HKZH 3GTPF 3S1QF 1I6VE 5BYHE 3RZOF 2R7ZE 2R7ZF 4GZYE 4KMUE 3S1MF 1TWGE 1TWGF 3PO2F 3HKZK 2JA5E 3GTOE 2JA5F 3GTOF 4A3EE 1I6HE 4YFXE 3EQLE 4KN4E 4YFKE 4A3FE 2PMZH 1TWAF 3GTME 3HOVE 2A69E 4OIPE 4BBRE 3WODE 5E18E 3CQZE 3CQZF 4G7ZE 2JA7F 4A3KF 2KRXA 4A3ME 2R92E 4A3MF 4BY7E 4BY7F 1SMYE 2JA8E 5M5XE 1TWHF 3S15E 2PMZK 5C44F 3S15F 3DXJE 2JA6F 4A3GE 3GTGF 1YNJK 4BXXF 3GTLE 3HOUE 3I4NE 5IP7F 2BE5E 5FLME 4A3LF 4C3HF 3GTQE
chains in the Genus database with same CATH topology
3GTJE 4A3BE 3S1QE 3RZOE 2WAQH 1EIKA 3S1ME 3S2HE 3PO2E 1TWAE 3FKIE 3HOYE 2JA7E 4A3KE 2VUME 3S14E 2Y0SH 3PO3E 1TWHE 5C44E 2JA6E 4X6AE 3GTGE 4BXXE 5IP7E 1Y1VE 1K83E 4A3LE 4C2ME 4C3HE 3GTPE 2NVXE 5IYDE 4A3IE 1SFOE 4BY1E 1DZFA 4AYBH 2R93E 1R9TE 5C4JE 1I50E 3HOWE 5IYBE 1I3QE 2YU9E 2NVQE 3GTKE 3HOZE 5IP9E 4C3JE 4BBSE 2NVYE 4A3JE 2E2IE 2WB1H 2E2JE 5C3EE 5M3ME 5C4XE 3S17E 5IYCE 4A3CE 5M5WE 3M3YE 1TWCE 5FJ8E 5M3FE 4A3DE 4Y7NE 4QIWH 3K7AE 3RZDE 1WCME 1TWFE 2B63E 3S2DE 3S1NE 4A93E 3HOXE 3S16E 3H3VF 4Y52E 1Y1WE 5M5YE 3M4OE 2NVTE 4C3IE 3S1RE 3I4ME 2E2HE 3H0GE 3HKZH 2R7ZE 1TWGE 2JA5E 3GTOE 4A3EE 1I6HE 4A3FE 2PMZH 3GTME 3HOVE 4BBRE 3CQZE 4A3ME 2R92E 4BY7E 2JA8E 5M5XE 3S15E 4A3GE 3GTLE 3HOUE 3I4NE 5FLME 3GTQE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTJ E;  4A3B E;  3S1Q E;  3RZO E;  2WAQ H;  1EIK A;  3S1M E;  3S2H E;  3PO2 E;  1TWA E;  3FKI E;  3HOY E;  2JA7 E;  4A3K E;  2VUM E;  3S14 E;  2Y0S H;  3PO3 E;  1TWH E;  5C44 E;  2JA6 E;  4X6A E;  3GTG E;  4BXX E;  5IP7 E;  1Y1V E;  1K83 E;  4A3L E;  4C2M E;  4C3H E;  3GTP E;  2NVX E;  5IYD E;  4A3I E;  1SFO E;  4BY1 E;  1DZF A;  4AYB H;  2R93 E;  1R9T E;  5C4J E;  1I50 E;  3HOW E;  5IYB E;  1I3Q E;  2YU9 E;  2NVQ E;  3GTK E;  3HOZ E;  5IP9 E;  4C3J E;  4BBS E;  2NVY E;  4A3J E;  2E2I E;  2WB1 H;  2E2J E;  5C3E E;  5M3M E;  5C4X E;  3S17 E;  5IYC E;  4A3C E;  5M5W E;  3M3Y E;  1TWC E;  5FJ8 E;  5M3F E;  4A3D E;  4Y7N E;  4QIW H;  3K7A E;  3RZD E;  1WCM E;  1TWF E;  2B63 E;  3S2D E;  3S1N E;  4A93 E;  3HOX E;  3S16 E;  3H3V F;  4Y52 E;  1Y1W E;  5M5Y E;  3M4O E;  2NVT E;  4C3I E;  3S1R E;  3I4M E;  2E2H E;  3H0G E;  3HKZ H;  2R7Z E;  1TWG E;  2JA5 E;  3GTO E;  4A3E E;  1I6H E;  4A3F E;  2PMZ H;  3GTM E;  3HOV E;  4BBR E;  3CQZ E;  4A3M E;  2R92 E;  4BY7 E;  2JA8 E;  5M5X E;  3S15 E;  4A3G E;  3GTL E;  3HOU E;  3I4N E;  5FLM E;  3GTQ E; 
#chains in the Genus database with same CATH topology
 3GTJ E;  4A3B E;  4A3B F;  4A3I F;  4BBS F;  1SFO F;  3S1Q E;  4BY1 F;  3RZO E;  2WAQ H;  4XSX E;  1IW7 E;  4G7O E;  1EIK A;  3S1M E;  3S2H E;  3S2H F;  3PO2 E;  2R93 F;  2O5J E;  1R9T F;  3HOW F;  2WAQ K;  1ZYR E;  1TWA E;  4ZH4 E;  1I3Q F;  5D4C E;  3FKI E;  3HOY E;  3FKI F;  4KN7 E;  2JA7 E;  2YU9 F;  3HOY F;  4A3K E;  2NVQ F;  3HOZ F;  4C3J F;  4YFN E;  2NVY F;  2E2I F;  5D4E E;  2VUM E;  2VUM F;  3S14 E;  1HQM E;  2A6H E;  3PO3 E;  2Y0S H;  3S14 F;  1TWH E;  5C44 E;  3PO3 F;  2JA6 E;  4LLG E;  4X6A E;  3GTG E;  3H3V G;  4X6A F;  2E2J F;  4BXX E;  5IP7 E;  5C3E F;  5E17 E;  5M3M F;  1Y1V E;  1K83 E;  1K83 F;  4A3L E;  1Y1V F;  4C2M E;  4C2M F;  4C3H E;  3GTP E;  1QKL A;  4OIR E;  5IYC F;  2NVX E;  4YG2 E;  2NVX F;  5IYD E;  4A3I E;  5IYD F;  4A3C F;  2A6E E;  5D4D E;  1SFO E;  5M5W F;  3M3Y F;  4BY1 E;  1DZF A;  4XSZ E;  5M3F F;  4AYB H;  4XLN E;  4Y7N F;  2R93 E;  2Y0S I;  4OIN E;  1R9T E;  5C4J E;  5C4J F;  1I50 E;  3HOW E;  1I50 F;  1TWF F;  1WCM F;  5IYB E;  4LK1 E;  5IYB F;  2B63 F;  1I3Q E;  2YU9 E;  4AYB K;  4A93 F;  4Q4Z E;  3HOX F;  4Y52 F;  2NVQ E;  3GTK E;  3HOZ E;  5IP9 E;  5IP9 F;  4C3J E;  4BBS E;  1Y1W F;  2NVY E;  4A3J E;  2E2I E;  5M5Y F;  4MQ9 E;  4A3J F;  4MEX E;  2WB1 H;  3GTM F;  2NVT F;  2O5I E;  4C3I F;  3S1R F;  2E2J E;  3H0G F;  4LK0 E;  5C3E E;  2E2H F;  5M3M E;  5C4X E;  5C4X F;  4MEY E;  3S17 E;  3S17 F;  4LJZ E;  4Q5S E;  5IYC E;  4A3C E;  2PPB E;  5M5W E;  3M3Y E;  1YNN K;  1TWC E;  1TWC F;  2CW0 E;  4OIQ E;  4A3E F;  5FJ8 E;  5TMF E;  5FJ8 F;  1I6H F;  4JK1 E;  3GTK F;  5M3F E;  4A3F F;  5IPL E;  4A3D E;  3HOV F;  4Y7N E;  4XLP E;  4G7H E;  4BBR F;  4A3D F;  2WB1 I;  4QIW H;  2A68 E;  3K7A E;  3RZD E;  3K7A F;  1WCM E;  1TWF E;  2B63 E;  3S2D E;  3RZD F;  2R92 F;  3S1N E;  3S2D F;  3S1N F;  2JA8 F;  4A93 E;  3HOX E;  3S16 E;  5M5X F;  3H3V F;  3S16 F;  4Y52 E;  4QIW K;  4A3G F;  1Y1W E;  3GTL F;  5M5Y E;  3HOU F;  3I4N F;  4OIO E;  3M4O E;  3M4O F;  5FLM F;  2NVT E;  3GTQ F;  4C3I E;  3S1R E;  5TMC E;  3I4M E;  3GTJ F;  3I4M F;  2E2H E;  3H0G E;  3HKZ H;  3GTP F;  3S1Q F;  1I6V E;  5BYH E;  3RZO F;  2R7Z E;  2R7Z F;  4GZY E;  4KMU E;  3S1M F;  1TWG E;  1TWG F;  3PO2 F;  3HKZ K;  2JA5 E;  3GTO E;  2JA5 F;  3GTO F;  4A3E E;  1I6H E;  4YFX E;  3EQL E;  4KN4 E;  4YFK E;  4A3F E;  2PMZ H;  1TWA F;  3GTM E;  3HOV E;  2A69 E;  4OIP E;  4BBR E;  3WOD E;  5E18 E;  3CQZ E;  3CQZ F;  4G7Z E;  2JA7 F;  4A3K F;  2KRX A;  4A3M E;  2R92 E;  4A3M F;  4BY7 E;  4BY7 F;  1SMY E;  2JA8 E;  5M5X E;  1TWH F;  3S15 E;  2PMZ K;  5C44 F;  3S15 F;  3DXJ E;  2JA6 F;  4A3G E;  3GTG F;  1YNJ K;  4BXX F;  3GTL E;  3HOU E;  3I4N E;  5IP7 F;  2BE5 E;  5FLM E;  4A3L F;  4C3H F;  3GTQ E; 
#chains in the Genus database with same CATH homology
 3GTJ E;  4A3B E;  3S1Q E;  3RZO E;  2WAQ H;  1EIK A;  3S1M E;  3S2H E;  3PO2 E;  1TWA E;  3FKI E;  3HOY E;  2JA7 E;  4A3K E;  2VUM E;  3S14 E;  2Y0S H;  3PO3 E;  1TWH E;  5C44 E;  2JA6 E;  4X6A E;  3GTG E;  4BXX E;  5IP7 E;  1Y1V E;  1K83 E;  4A3L E;  4C2M E;  4C3H E;  3GTP E;  2NVX E;  5IYD E;  4A3I E;  1SFO E;  4BY1 E;  1DZF A;  4AYB H;  2R93 E;  1R9T E;  5C4J E;  1I50 E;  3HOW E;  5IYB E;  1I3Q E;  2YU9 E;  2NVQ E;  3GTK E;  3HOZ E;  5IP9 E;  4C3J E;  4BBS E;  2NVY E;  4A3J E;  2E2I E;  2WB1 H;  2E2J E;  5C3E E;  5M3M E;  5C4X E;  3S17 E;  5IYC E;  4A3C E;  5M5W E;  3M3Y E;  1TWC E;  5FJ8 E;  5M3F E;  4A3D E;  4Y7N E;  4QIW H;  3K7A E;  3RZD E;  1WCM E;  1TWF E;  2B63 E;  3S2D E;  3S1N E;  4A93 E;  3HOX E;  3S16 E;  3H3V F;  4Y52 E;  1Y1W E;  5M5Y E;  3M4O E;  2NVT E;  4C3I E;  3S1R E;  3I4M E;  2E2H E;  3H0G E;  3HKZ H;  2R7Z E;  1TWG E;  2JA5 E;  3GTO E;  4A3E E;  1I6H E;  4A3F E;  2PMZ H;  3GTM E;  3HOV E;  4BBR E;  3CQZ E;  4A3M E;  2R92 E;  4BY7 E;  2JA8 E;  5M5X E;  3S15 E;  4A3G E;  3GTL E;  3HOU E;  3I4N E;  5FLM E;  3GTQ E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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