2LFKA

Nmr solution structure of native tdpi-short
Total Genus 3
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
57
structure length
57
Chain Sequence
GDKEECTVPIGWSEPVKGLCKARFTRYYCMGNCCKVYEGCYTGGYSRMGECARNCPG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase inhibitor
source organism Rhipicephalus appendiculatus
publication title Oxidative folding and structural analyses of a kunitz-related inhibitor and its disulfide intermediates: functional implications.
pubmed doi rcsb
molecule keywords Tryptase inhibitor
total genus 3
structure length 57
sequence length 57
ec nomenclature
pdb deposition date 2011-07-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 2lfkA01
1F5RI 1JC6A 1DENA 2TPII 3AUDA 3AUHA 3AUEA 4ISOB 3BTQI 1KIGI 1T8LB 3AUBA 1PITA 3TGJI 1TPAI 3UIRC 2TGPI 3BTTI 2DDJA 4WXVC 2IJOI 1T8NB 2FI5I 1FY8I 2FTLI 3WNYA 1P2II 1BPIA 2RA3C 3L3TE 4U32X 1CO7I 3BTFI 2JOTA 1P2NB 2KNTA 1UUAA 3P95E 1QLQA 1AALA 2LFLA 1BF0A 3OFWA 4U30W 1BUNB 2FI3I 3L33E 4Y10I 4BD9B 1P2JI 1ZJDB 1BRBI 1KTHA 2M99A 3BTHI 3BTMI 4BQDA 1F7ZI 1P2OB 3BYBA 1D0DA 1G6XA 1FAKI 4Y0ZI 3AUGA 2KAII 3D65I 1BIKA 3T62D 4NTYB 1JV9A 1DTXA 1BHCA 3BTDI 1EJMB 1CA0D 1EAWB 2CA7A 1UUBA 2DDIA 1YLCB 2ODYE 5JB6A 3BTGI 1YC0I 2J6DA 1B0CA 4WWYC 3U1JE 1BZ5A 3FP7J 3CI7A 2UUYB 1NAGA 5C67C 1LD6A 5JB4A 3AUIA 3FP6I 3TGKI 1TOCR 3OTJI 4TPII 1FANA 1OA65 5JB7A 4DG4C 2LFKA 4ISLB 1SHPA 1DTKA 3P92E 7PTIA 2UUXA 1P2KI 1BTHP 1T8OB 1KNTA 2R9PE 1Y62A 4Y11I 6PTIA 1ADZA 3TPII 4DTGK 1BTIA 1MTND 3FP8I 1K6UA 1P2QB 2FTMB 3LDJA 3M7QB 2ZJXA 3GYMI 2ZVXA 4PTIA 9PTIA 1DEMA 1JV8A 2HEXA 2M01A 3BTKI 3LDMA 1CBWD 1BZXI 3AUCA 1OA55 1BRCI 1YKTB 1ZR0B 1KUNA 1YLDB 4ISNB 1TCPA 1T8MB 3UOUB 4Y0YI 3BTWI 4NTXB 4BNRI 2KCRA 5JB5A 1D0DB 1T7CB 1TAPA 1TFXC 8PTIA 1IRHA 1TAWB 1LD5A 2W8XA 5PTIA 1P2MB 2PTCI 1BPTA 3BTEI 3LDIA 2FI4I 3TGII 1AAPA 4NTWB
chains in the Genus database with same CATH superfamily
1F5RI 1JC6A 1DENA 2TPII 3AUDA 3AUHA 3AUEA 4ISOB 3BTQI 1KIGI 1T8LB 3AUBA 1PITA 3TGJI 1TPAI 3UIRC 2TGPI 3BTTI 2DDJA 4WXVC 2IJOI 1T8NB 2FI5I 1FY8I 2FTLI 3WNYA 1P2II 1BPIA 2RA3C 3L3TE 4U32X 1CO7I 3BTFI 2JOTA 1P2NB 2KNTA 1UUAA 3P95E 1QLQA 1AALA 2LFLA 1BF0A 3OFWA 4U30W 1BUNB 2FI3I 3L33E 4Y10I 4BD9B 1P2JI 1ZJDB 1BRBI 1KTHA 2M99A 3BTHI 3BTMI 4BQDA 1F7ZI 1P2OB 3BYBA 1D0DA 1G6XA 1FAKI 4Y0ZI 3AUGA 2KAII 3D65I 1BIKA 3T62D 4NTYB 1JV9A 1DTXA 1BHCA 3BTDI 1EJMB 1CA0D 1EAWB 2CA7A 1UUBA 2DDIA 1YLCB 2ODYE 5JB6A 3BTGI 1YC0I 2J6DA 1B0CA 4WWYC 3U1JE 1BZ5A 3FP7J 3CI7A 2UUYB 1NAGA 5C67C 1LD6A 5JB4A 3AUIA 3FP6I 3TGKI 1TOCR 3OTJI 4TPII 1FANA 1OA65 5JB7A 4DG4C 2LFKA 4ISLB 1SHPA 1DTKA 3P92E 7PTIA 2UUXA 1P2KI 1BTHP 1T8OB 1KNTA 2R9PE 1Y62A 4Y11I 6PTIA 1ADZA 3TPII 4DTGK 1BTIA 1MTND 3FP8I 1K6UA 1P2QB 2FTMB 3LDJA 3M7QB 2ZJXA 3GYMI 2ZVXA 4PTIA 9PTIA 1DEMA 1JV8A 2HEXA 2M01A 3BTKI 3LDMA 1CBWD 1BZXI 3AUCA 1OA55 1BRCI 1YKTB 1ZR0B 1KUNA 1YLDB 4ISNB 1TCPA 1T8MB 3UOUB 4Y0YI 3BTWI 4NTXB 4BNRI 2KCRA 5JB5A 1D0DB 1T7CB 1TAPA 1TFXC 8PTIA 1IRHA 1TAWB 1LD5A 2W8XA 5PTIA 1P2MB 2PTCI 1BPTA 3BTEI 3LDIA 2FI4I 3TGII 1AAPA 4NTWB
chains in the Genus database with same CATH topology
1F5RI 1JC6A 1DENA 2TPII 3AUDA 3AUHA 3AUEA 4ISOB 3BTQI 1KIGI 1T8LB 3AUBA 1PITA 3TGJI 1TPAI 3UIRC 2TGPI 3BTTI 2DDJA 4WXVC 2IJOI 1T8NB 2FI5I 1FY8I 2FTLI 3WNYA 1P2II 1BPIA 2RA3C 3L3TE 4U32X 1CO7I 3BTFI 2JOTA 1P2NB 2KNTA 1UUAA 3P95E 1QLQA 1AALA 2LFLA 1BF0A 3OFWA 4U30W 1BUNB 2FI3I 3L33E 4Y10I 4BD9B 1P2JI 1ZJDB 1BRBI 1KTHA 2M99A 3BTHI 3BTMI 4BQDA 1F7ZI 1P2OB 3BYBA 1D0DA 1G6XA 1FAKI 4Y0ZI 3AUGA 2KAII 3D65I 1BIKA 3T62D 4NTYB 1JV9A 1DTXA 1BHCA 3BTDI 1EJMB 1CA0D 1EAWB 2CA7A 1UUBA 2DDIA 1YLCB 2ODYE 5JB6A 3BTGI 1YC0I 2J6DA 1B0CA 4WWYC 3U1JE 1BZ5A 3FP7J 3CI7A 2UUYB 1NAGA 5C67C 1LD6A 5JB4A 3AUIA 3FP6I 3TGKI 1TOCR 3OTJI 4TPII 1FANA 1OA65 5JB7A 4DG4C 2LFKA 4ISLB 1SHPA 1DTKA 3P92E 7PTIA 2UUXA 1P2KI 1BTHP 1T8OB 1KNTA 2R9PE 1Y62A 4Y11I 6PTIA 1ADZA 3TPII 4DTGK 1BTIA 1MTND 3FP8I 1K6UA 1P2QB 2FTMB 3LDJA 3M7QB 2ZJXA 3GYMI 2ZVXA 4PTIA 9PTIA 1DEMA 1JV8A 2HEXA 2M01A 3BTKI 3LDMA 1CBWD 1BZXI 3AUCA 1OA55 1BRCI 1YKTB 1ZR0B 1KUNA 1YLDB 4ISNB 1TCPA 1T8MB 3UOUB 4Y0YI 3BTWI 4NTXB 4BNRI 2KCRA 5JB5A 1D0DB 1T7CB 1TAPA 1TFXC 8PTIA 1IRHA 1TAWB 1LD5A 2W8XA 5PTIA 1P2MB 2PTCI 1BPTA 3BTEI 3LDIA 2FI4I 3TGII 1AAPA 4NTWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F5R I;  1JC6 A;  1DEN A;  2TPI I;  3AUD A;  3AUH A;  3AUE A;  4ISO B;  3BTQ I;  1KIG I;  1T8L B;  3AUB A;  1PIT A;  3TGJ I;  1TPA I;  3UIR C;  2TGP I;  3BTT I;  2DDJ A;  4WXV C;  2IJO I;  1T8N B;  2FI5 I;  1FY8 I;  2FTL I;  3WNY A;  1P2I I;  1BPI A;  2RA3 C;  3L3T E;  4U32 X;  1CO7 I;  3BTF I;  2JOT A;  1P2N B;  2KNT A;  1UUA A;  3P95 E;  1QLQ A;  1AAL A;  2LFL A;  1BF0 A;  3OFW A;  4U30 W;  1BUN B;  2FI3 I;  3L33 E;  4Y10 I;  4BD9 B;  1P2J I;  1ZJD B;  1BRB I;  1KTH A;  2M99 A;  3BTH I;  3BTM I;  4BQD A;  1F7Z I;  1P2O B;  3BYB A;  1D0D A;  1G6X A;  1FAK I;  4Y0Z I;  3AUG A;  2KAI I;  3D65 I;  1BIK A;  3T62 D;  4NTY B;  1JV9 A;  1DTX A;  1BHC A;  3BTD I;  1EJM B;  1CA0 D;  1EAW B;  2CA7 A;  1UUB A;  2DDI A;  1YLC B;  2ODY E;  5JB6 A;  3BTG I;  1YC0 I;  2J6D A;  1B0C A;  4WWY C;  3U1J E;  1BZ5 A;  3FP7 J;  3CI7 A;  2UUY B;  1NAG A;  5C67 C;  1LD6 A;  5JB4 A;  3AUI A;  3FP6 I;  3TGK I;  1TOC R;  3OTJ I;  4TPI I;  1FAN A;  1OA6 5;  5JB7 A;  4DG4 C;  2LFK A;  4ISL B;  1SHP A;  1DTK A;  3P92 E;  7PTI A;  2UUX A;  1P2K I;  1BTH P;  1T8O B;  1KNT A;  2R9P E;  1Y62 A;  4Y11 I;  6PTI A;  1ADZ A;  3TPI I;  4DTG K;  1BTI A;  1MTN D;  3FP8 I;  1K6U A;  1P2Q B;  2FTM B;  3LDJ A;  3M7Q B;  2ZJX A;  3GYM I;  2ZVX A;  4PTI A;  9PTI A;  1DEM A;  1JV8 A;  2HEX A;  2M01 A;  3BTK I;  3LDM A;  1CBW D;  1BZX I;  3AUC A;  1OA5 5;  1BRC I;  1YKT B;  1ZR0 B;  1KUN A;  1YLD B;  4ISN B;  1TCP A;  1T8M B;  3UOU B;  4Y0Y I;  3BTW I;  4NTX B;  4BNR I;  2KCR A;  5JB5 A;  1D0D B;  1T7C B;  1TAP A;  1TFX C;  8PTI A;  1IRH A;  1TAW B;  1LD5 A;  2W8X A;  5PTI A;  1P2M B;  2PTC I;  1BPT A;  3BTE I;  3LDI A;  2FI4 I;  3TGI I;  1AAP A;  4NTW B; 
#chains in the Genus database with same CATH topology
 1F5R I;  1JC6 A;  1DEN A;  2TPI I;  3AUD A;  3AUH A;  3AUE A;  4ISO B;  3BTQ I;  1KIG I;  1T8L B;  3AUB A;  1PIT A;  3TGJ I;  1TPA I;  3UIR C;  2TGP I;  3BTT I;  2DDJ A;  4WXV C;  2IJO I;  1T8N B;  2FI5 I;  1FY8 I;  2FTL I;  3WNY A;  1P2I I;  1BPI A;  2RA3 C;  3L3T E;  4U32 X;  1CO7 I;  3BTF I;  2JOT A;  1P2N B;  2KNT A;  1UUA A;  3P95 E;  1QLQ A;  1AAL A;  2LFL A;  1BF0 A;  3OFW A;  4U30 W;  1BUN B;  2FI3 I;  3L33 E;  4Y10 I;  4BD9 B;  1P2J I;  1ZJD B;  1BRB I;  1KTH A;  2M99 A;  3BTH I;  3BTM I;  4BQD A;  1F7Z I;  1P2O B;  3BYB A;  1D0D A;  1G6X A;  1FAK I;  4Y0Z I;  3AUG A;  2KAI I;  3D65 I;  1BIK A;  3T62 D;  4NTY B;  1JV9 A;  1DTX A;  1BHC A;  3BTD I;  1EJM B;  1CA0 D;  1EAW B;  2CA7 A;  1UUB A;  2DDI A;  1YLC B;  2ODY E;  5JB6 A;  3BTG I;  1YC0 I;  2J6D A;  1B0C A;  4WWY C;  3U1J E;  1BZ5 A;  3FP7 J;  3CI7 A;  2UUY B;  1NAG A;  5C67 C;  1LD6 A;  5JB4 A;  3AUI A;  3FP6 I;  3TGK I;  1TOC R;  3OTJ I;  4TPI I;  1FAN A;  1OA6 5;  5JB7 A;  4DG4 C;  2LFK A;  4ISL B;  1SHP A;  1DTK A;  3P92 E;  7PTI A;  2UUX A;  1P2K I;  1BTH P;  1T8O B;  1KNT A;  2R9P E;  1Y62 A;  4Y11 I;  6PTI A;  1ADZ A;  3TPI I;  4DTG K;  1BTI A;  1MTN D;  3FP8 I;  1K6U A;  1P2Q B;  2FTM B;  3LDJ A;  3M7Q B;  2ZJX A;  3GYM I;  2ZVX A;  4PTI A;  9PTI A;  1DEM A;  1JV8 A;  2HEX A;  2M01 A;  3BTK I;  3LDM A;  1CBW D;  1BZX I;  3AUC A;  1OA5 5;  1BRC I;  1YKT B;  1ZR0 B;  1KUN A;  1YLD B;  4ISN B;  1TCP A;  1T8M B;  3UOU B;  4Y0Y I;  3BTW I;  4NTX B;  4BNR I;  2KCR A;  5JB5 A;  1D0D B;  1T7C B;  1TAP A;  1TFX C;  8PTI A;  1IRH A;  1TAW B;  1LD5 A;  2W8X A;  5PTI A;  1P2M B;  2PTC I;  1BPT A;  3BTE I;  3LDI A;  2FI4 I;  3TGI I;  1AAP A;  4NTW B; 
#chains in the Genus database with same CATH homology
 1F5R I;  1JC6 A;  1DEN A;  2TPI I;  3AUD A;  3AUH A;  3AUE A;  4ISO B;  3BTQ I;  1KIG I;  1T8L B;  3AUB A;  1PIT A;  3TGJ I;  1TPA I;  3UIR C;  2TGP I;  3BTT I;  2DDJ A;  4WXV C;  2IJO I;  1T8N B;  2FI5 I;  1FY8 I;  2FTL I;  3WNY A;  1P2I I;  1BPI A;  2RA3 C;  3L3T E;  4U32 X;  1CO7 I;  3BTF I;  2JOT A;  1P2N B;  2KNT A;  1UUA A;  3P95 E;  1QLQ A;  1AAL A;  2LFL A;  1BF0 A;  3OFW A;  4U30 W;  1BUN B;  2FI3 I;  3L33 E;  4Y10 I;  4BD9 B;  1P2J I;  1ZJD B;  1BRB I;  1KTH A;  2M99 A;  3BTH I;  3BTM I;  4BQD A;  1F7Z I;  1P2O B;  3BYB A;  1D0D A;  1G6X A;  1FAK I;  4Y0Z I;  3AUG A;  2KAI I;  3D65 I;  1BIK A;  3T62 D;  4NTY B;  1JV9 A;  1DTX A;  1BHC A;  3BTD I;  1EJM B;  1CA0 D;  1EAW B;  2CA7 A;  1UUB A;  2DDI A;  1YLC B;  2ODY E;  5JB6 A;  3BTG I;  1YC0 I;  2J6D A;  1B0C A;  4WWY C;  3U1J E;  1BZ5 A;  3FP7 J;  3CI7 A;  2UUY B;  1NAG A;  5C67 C;  1LD6 A;  5JB4 A;  3AUI A;  3FP6 I;  3TGK I;  1TOC R;  3OTJ I;  4TPI I;  1FAN A;  1OA6 5;  5JB7 A;  4DG4 C;  2LFK A;  4ISL B;  1SHP A;  1DTK A;  3P92 E;  7PTI A;  2UUX A;  1P2K I;  1BTH P;  1T8O B;  1KNT A;  2R9P E;  1Y62 A;  4Y11 I;  6PTI A;  1ADZ A;  3TPI I;  4DTG K;  1BTI A;  1MTN D;  3FP8 I;  1K6U A;  1P2Q B;  2FTM B;  3LDJ A;  3M7Q B;  2ZJX A;  3GYM I;  2ZVX A;  4PTI A;  9PTI A;  1DEM A;  1JV8 A;  2HEX A;  2M01 A;  3BTK I;  3LDM A;  1CBW D;  1BZX I;  3AUC A;  1OA5 5;  1BRC I;  1YKT B;  1ZR0 B;  1KUN A;  1YLD B;  4ISN B;  1TCP A;  1T8M B;  3UOU B;  4Y0Y I;  3BTW I;  4NTX B;  4BNR I;  2KCR A;  5JB5 A;  1D0D B;  1T7C B;  1TAP A;  1TFX C;  8PTI A;  1IRH A;  1TAW B;  1LD5 A;  2W8X A;  5PTI A;  1P2M B;  2PTC I;  1BPT A;  3BTE I;  3LDI A;  2FI4 I;  3TGI I;  1AAP A;  4NTW B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...