2NL8A

The origin binding domain of the sv40 large t antigen bound non specifically to a 17 bp palindrome dna (sites 1 and 3)
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
117
structure length
117
Chain Sequence
EDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLSTFSFLICKGVNKEYLMYSALTRDPFSVIEESLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Simian virus 40
molecule keywords 18-nt PEN element of the SV40 DNA origin
total genus 29
structure length 117
sequence length 117
ec nomenclature
pdb deposition date 2006-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 2nl8A00
2ITLA 1UUTA 4ZO0A 4LIFA 5DCXA 4FB3A 5D9IA 3QN2A 1L2MA 2ITJA 2IF9A 4NBPA 2NTCA 4FGNA 1RZ9A 2FUFA 1Z1DB 2IPRA 4GDFA 5BYGA 1TBDA 3QFQA 1L5IA 2NL8A 2HW0A 1M55A 3QK2A 4ZQ9A 2TBDA 4LMDA 5CYNA
chains in the Genus database with same CATH superfamily
2ITLA 1UUTA 4ZO0A 1R9WA 4LIFA 5DCXA 4FB3A 5D9IA 3QN2A 1L2MA 2ITJA 2IF9A 4NBPA 2NTCA 4U87A 4FGNA 1RZ9A 3DKYA 2FUFA 1F08A 1Z1DB 2IPRA 3DKXA 4GDFA 5BYGA 1TBDA 3QFQA 1L5IA 1KSXA 2NL8A 2HW0A 1KSYA 1M55A 3QK2A 4KW3A 4ZQ9A 2TBDA 4LMDA 5CYNA
chains in the Genus database with same CATH topology
2ITLA 1UUTA 4ZO0A 1R9WA 4LIFA 5DCXA 4FB3A 5D9IA 3QN2A 1L2MA 2ITJA 2IF9A 4NBPA 2NTCA 4U87A 4FGNA 1RZ9A 3DKYA 2FUFA 1F08A 1Z1DB 2IPRA 3DKXA 4GDFA 5BYGA 1TBDA 3QFQA 1L5IA 1KSXA 2NL8A 2HW0A 1KSYA 1M55A 3QK2A 4KW3A 4ZQ9A 2TBDA 4LMDA 5CYNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ITL A;  1UUT A;  4ZO0 A;  4LIF A;  5DCX A;  4FB3 A;  5D9I A;  3QN2 A;  1L2M A;  2ITJ A;  2IF9 A;  4NBP A;  2NTC A;  4FGN A;  1RZ9 A;  2FUF A;  1Z1D B;  2IPR A;  4GDF A;  5BYG A;  1TBD A;  3QFQ A;  1L5I A;  2NL8 A;  2HW0 A;  1M55 A;  3QK2 A;  4ZQ9 A;  2TBD A;  4LMD A;  5CYN A; 
#chains in the Genus database with same CATH topology
 2ITL A;  1UUT A;  4ZO0 A;  1R9W A;  4LIF A;  5DCX A;  4FB3 A;  5D9I A;  3QN2 A;  1L2M A;  2ITJ A;  2IF9 A;  4NBP A;  2NTC A;  4U87 A;  4FGN A;  1RZ9 A;  3DKY A;  2FUF A;  1F08 A;  1Z1D B;  2IPR A;  3DKX A;  4GDF A;  5BYG A;  1TBD A;  3QFQ A;  1L5I A;  1KSX A;  2NL8 A;  2HW0 A;  1KSY A;  1M55 A;  3QK2 A;  4KW3 A;  4ZQ9 A;  2TBD A;  4LMD A;  5CYN A; 
#chains in the Genus database with same CATH homology
 2ITL A;  1UUT A;  4ZO0 A;  1R9W A;  4LIF A;  5DCX A;  4FB3 A;  5D9I A;  3QN2 A;  1L2M A;  2ITJ A;  2IF9 A;  4NBP A;  2NTC A;  4U87 A;  4FGN A;  1RZ9 A;  3DKY A;  2FUF A;  1F08 A;  1Z1D B;  2IPR A;  3DKX A;  4GDF A;  5BYG A;  1TBD A;  3QFQ A;  1L5I A;  1KSX A;  2NL8 A;  2HW0 A;  1KSY A;  1M55 A;  3QK2 A;  4KW3 A;  4ZQ9 A;  2TBD A;  4LMD A;  5CYN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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