2NL8A

The origin binding domain of the sv40 large t antigen bound non specifically to a 17 bp palindrome dna (sites 1 and 3)
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
117
structure length
117
Chain Sequence
EDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLSTFSFLICKGVNKEYLMYSALTRDPFSVIEESLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
pubmed doi rcsb
molecule keywords 18-nt PEN element of the SV40 DNA origin
molecule tags Dna binding protein/dna
source organism Simian virus 40
total genus 29
structure length 117
sequence length 117
ec nomenclature
pdb deposition date 2006-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 2nl8A00
5DCXA 3QN2A 2ITJA 4ZQ9A 2IPRA 3QK2A 3QFQA 2FUFA 4LMDA 1M55A 1Z1DB 2ITLA 4GDFA 1TBDA 1L5IA 4FGNA 2NTCA 5D9IA 4FB3A 2HW0A 5BYGA 1UUTA 4LIFA 1L2MA 4ZO0A 2IF9A 2TBDA 1RZ9A 5CYNA 4NBPA 2NL8A
chains in the Genus database with same CATH superfamily
5DCXA 3QN2A 2ITJA 4ZQ9A 2IPRA 3QK2A 3QFQA 4NBPA 2FUFA 4LMDA 1F08A 4KW3A 1M55A 4GDFA 2ITLA 1TBDA 1L5IA 4FGNA 2NTCA 5CYNA 1KSYA 5D9IA 4FB3A 2HW0A 5BYGA 1UUTA 1KSXA 1R9WA 4LIFA 1L2MA 3DKYA 4ZO0A 4U87A 2TBDA 3DKXA 1RZ9A 1Z1DB 2IF9A 2NL8A
chains in the Genus database with same CATH topology
5DCXA 3QN2A 2ITJA 4ZQ9A 2IPRA 3QK2A 3QFQA 4NBPA 2FUFA 4LMDA 1F08A 4KW3A 1M55A 4GDFA 2ITLA 1TBDA 1L5IA 4FGNA 2NTCA 5CYNA 1KSYA 5D9IA 4FB3A 2HW0A 5BYGA 1UUTA 1KSXA 1R9WA 4LIFA 1L2MA 3DKYA 4ZO0A 4U87A 2TBDA 3DKXA 1RZ9A 1Z1DB 2IF9A 2NL8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DCX A;  3QN2 A;  2ITJ A;  4ZQ9 A;  2IPR A;  3QK2 A;  3QFQ A;  2FUF A;  4LMD A;  1M55 A;  1Z1D B;  2ITL A;  4GDF A;  1TBD A;  1L5I A;  4FGN A;  2NTC A;  5D9I A;  4FB3 A;  2HW0 A;  5BYG A;  1UUT A;  4LIF A;  1L2M A;  4ZO0 A;  2IF9 A;  2TBD A;  1RZ9 A;  5CYN A;  4NBP A;  2NL8 A; 
#chains in the Genus database with same CATH topology
 5DCX A;  3QN2 A;  2ITJ A;  4ZQ9 A;  2IPR A;  3QK2 A;  3QFQ A;  4NBP A;  2FUF A;  4LMD A;  1F08 A;  4KW3 A;  1M55 A;  4GDF A;  2ITL A;  1TBD A;  1L5I A;  4FGN A;  2NTC A;  5CYN A;  1KSY A;  5D9I A;  4FB3 A;  2HW0 A;  5BYG A;  1UUT A;  1KSX A;  1R9W A;  4LIF A;  1L2M A;  3DKY A;  4ZO0 A;  4U87 A;  2TBD A;  3DKX A;  1RZ9 A;  1Z1D B;  2IF9 A;  2NL8 A; 
#chains in the Genus database with same CATH homology
 5DCX A;  3QN2 A;  2ITJ A;  4ZQ9 A;  2IPR A;  3QK2 A;  3QFQ A;  4NBP A;  2FUF A;  4LMD A;  1F08 A;  4KW3 A;  1M55 A;  4GDF A;  2ITL A;  1TBD A;  1L5I A;  4FGN A;  2NTC A;  5CYN A;  1KSY A;  5D9I A;  4FB3 A;  2HW0 A;  5BYG A;  1UUT A;  1KSX A;  1R9W A;  4LIF A;  1L2M A;  3DKY A;  4ZO0 A;  4U87 A;  2TBD A;  3DKX A;  1RZ9 A;  1Z1D B;  2IF9 A;  2NL8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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