2NL8A

The origin binding domain of the sv40 large t antigen bound non specifically to a 17 bp palindrome dna (sites 1 and 3)
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
117
structure length
117
Chain Sequence
EDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLSTFSFLICKGVNKEYLMYSALTRDPFSVIEESLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Simian virus 40
molecule keywords 18-nt PEN element of the SV40 DNA origin
total genus 29
structure length 117
sequence length 117
ec nomenclature
pdb deposition date 2006-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 2nl8A00
1M55A 2FUFA 3QK2A 5CYNA 4ZQ9A 2ITLA 1L5IA 4FB3A 2ITJA 2HW0A 3QN2A 2NTCA 5BYGA 4ZO0A 1UUTA 2NL8A 4LMDA 5D9IA 1RZ9A 3QFQA 2IF9A 1L2MA 4GDFA 1TBDA 2TBDA 4FGNA 1Z1DB 4NBPA 2IPRA 5DCXA 4LIFA
chains in the Genus database with same CATH superfamily
1M55A 2FUFA 3QK2A 5CYNA 4ZQ9A 1KSYA 2ITLA 1L5IA 4FB3A 2ITJA 2HW0A 3QN2A 2NTCA 4U87A 5BYGA 4KW3A 4ZO0A 1UUTA 2NL8A 4LMDA 5D9IA 1RZ9A 3DKXA 3QFQA 1F08A 2IF9A 1L2MA 1KSXA 4GDFA 1TBDA 2TBDA 4FGNA 1Z1DB 4NBPA 3DKYA 2IPRA 1R9WA 5DCXA 4LIFA
chains in the Genus database with same CATH topology
1M55A 2FUFA 3QK2A 5CYNA 4ZQ9A 1KSYA 2ITLA 1L5IA 4FB3A 2ITJA 2HW0A 3QN2A 2NTCA 4U87A 5BYGA 4KW3A 4ZO0A 1UUTA 2NL8A 4LMDA 5D9IA 1RZ9A 3DKXA 3QFQA 1F08A 2IF9A 1L2MA 1KSXA 4GDFA 1TBDA 2TBDA 4FGNA 1Z1DB 4NBPA 3DKYA 2IPRA 1R9WA 5DCXA 4LIFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M55 A;  2FUF A;  3QK2 A;  5CYN A;  4ZQ9 A;  2ITL A;  1L5I A;  4FB3 A;  2ITJ A;  2HW0 A;  3QN2 A;  2NTC A;  5BYG A;  4ZO0 A;  1UUT A;  2NL8 A;  4LMD A;  5D9I A;  1RZ9 A;  3QFQ A;  2IF9 A;  1L2M A;  4GDF A;  1TBD A;  2TBD A;  4FGN A;  1Z1D B;  4NBP A;  2IPR A;  5DCX A;  4LIF A; 
#chains in the Genus database with same CATH topology
 1M55 A;  2FUF A;  3QK2 A;  5CYN A;  4ZQ9 A;  1KSY A;  2ITL A;  1L5I A;  4FB3 A;  2ITJ A;  2HW0 A;  3QN2 A;  2NTC A;  4U87 A;  5BYG A;  4KW3 A;  4ZO0 A;  1UUT A;  2NL8 A;  4LMD A;  5D9I A;  1RZ9 A;  3DKX A;  3QFQ A;  1F08 A;  2IF9 A;  1L2M A;  1KSX A;  4GDF A;  1TBD A;  2TBD A;  4FGN A;  1Z1D B;  4NBP A;  3DKY A;  2IPR A;  1R9W A;  5DCX A;  4LIF A; 
#chains in the Genus database with same CATH homology
 1M55 A;  2FUF A;  3QK2 A;  5CYN A;  4ZQ9 A;  1KSY A;  2ITL A;  1L5I A;  4FB3 A;  2ITJ A;  2HW0 A;  3QN2 A;  2NTC A;  4U87 A;  5BYG A;  4KW3 A;  4ZO0 A;  1UUT A;  2NL8 A;  4LMD A;  5D9I A;  1RZ9 A;  3DKX A;  3QFQ A;  1F08 A;  2IF9 A;  1L2M A;  1KSX A;  4GDF A;  1TBD A;  2TBD A;  4FGN A;  1Z1D B;  4NBP A;  3DKY A;  2IPR A;  1R9W A;  5DCX A;  4LIF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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