2ODYE

Thrombin-bound boophilin displays a functional and accessible reactive-site loop
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
127
structure length
127
Chain Sequence
QRNGFCRLPADEGICKALIPRFYFNTETGKCTMFSYGGCGGNENNFETIEECQKACGAPERVNDFESADFKTGCEPAADSGSCAGQLERWFYNVQSGECETFVYGGCGGNDNNYESEEECELVCKNM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick.
pubmed doi rcsb
molecule tags Blood clotting/blood clotting inhibitor
source organism Rhipicephalus microplus
molecule keywords Prothrombin (EC 3.4.21.5)
total genus 28
structure length 127
sequence length 127
chains with identical sequence F
ec nomenclature
pdb deposition date 2006-12-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 2odyE02
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 2odyE01
1BHCA 1Y62A 2ODYE 3AUGA 4NTYB 2W8XA 1BZXI 1EJMB 1IRHA 3AUHA 1P2II 1QLQA 1YC0I 3LDIA 3TPII 1B0CA 3TGII 3M7QB 1BTHP 1T8NB 4ISOB 4WXVC 4BD9B 4DG4C 1EAWB 4Y11I 1P2NB 3L3TE 2M01A 3BTKI 1TOCR 1ZR0B 1P2OB 8PTIA 5JB6A 1KUNA 1TAPA 1CO7I 1TAWB 1BPIA 1LD5A 4Y0YI 3TGJI 3AUBA 3LDMA 2FI4I 2KAII 1BPTA 1BF0A 1P2JI 4DTGK 1P2MB 2KNTA 3CI7A 3UOUB 2DDIA 2FI5I 6PTIA 2JOTA 3BTHI 1BTIA 1OA65 3P95E 4ISLB 2KCRA 1F7ZI 4ISNB 1T8LB 1TFXC 1NAGA 1JC6A 2HEXA 4NTXB 4BQDA 5JB4A 1YLDB 1FANA 7PTIA 3FP8I 1KIGI 1P2QB 4U32X 3GYMI 3T62D 1DENA 1UUAA 1K6UA 3FP6I 2PTCI 1BUNB 1BZ5A 1CA0D 1YLCB 2FTMB 2ZVXA 3OFWA 3UIRC 3LDJA 1DTKA 1T8MB 2ZJXA 1ADZA 5PTIA 3D65I 1T7CB 1BRBI 3WNYA 1FAKI 1FY8I 1LD6A 3AUDA 2TPII 3BTDI 3BYBA 1KTHA 1AAPA 1JV8A 1PITA 3BTMI 3P92E 2IJOI 1G6XA 4PTIA 4NTWB 4BNRI 3BTTI 3BTEI 1CBWD 2LFKA 5JB7A 1BRCI 2R9PE 2RA3C 1ZJDB 2J6DA 1D0DB 2FTLI 1DTXA 9PTIA 5JB5A 3FP7J 3BTFI 4U30W 3BTQI 3U1JE 1UUBA 1D0DA 3TGKI 5C67C 3BTWI 2FI3I 2UUYB 1BIKA 4TPII 1SHPA 1KNTA 1YKTB 1OA55 3BTGI 1AALA 2DDJA 3AUCA 2TGPI 4Y10I 1T8OB 3L33E 3AUIA 2CA7A 2LFLA 3AUEA 1P2KI 2M99A 2UUXA 1DEMA 1F5RI 1TCPA 3OTJI 1MTND 4WWYC 4Y0ZI 1TPAI 1JV9A
chains in the Genus database with same CATH superfamily
1BHCA 1Y62A 2ODYE 3AUGA 4NTYB 2W8XA 1BZXI 1EJMB 1IRHA 3AUHA 1P2II 1QLQA 1YC0I 3LDIA 3TPII 1B0CA 3TGII 3M7QB 1BTHP 1T8NB 4ISOB 4WXVC 4BD9B 4DG4C 1EAWB 4Y11I 1P2NB 3L3TE 2M01A 3BTKI 1TOCR 1ZR0B 1P2OB 8PTIA 5JB6A 1KUNA 1TAPA 1CO7I 1TAWB 1BPIA 1LD5A 4Y0YI 3TGJI 3AUBA 3LDMA 2FI4I 2KAII 1BPTA 1BF0A 1P2JI 4DTGK 1P2MB 2KNTA 3CI7A 3UOUB 2DDIA 2FI5I 6PTIA 2JOTA 3BTHI 1BTIA 1OA65 3P95E 4ISLB 2KCRA 1F7ZI 4ISNB 1T8LB 1TFXC 1NAGA 1JC6A 2HEXA 4NTXB 4BQDA 5JB4A 1YLDB 1FANA 7PTIA 3FP8I 1KIGI 1P2QB 4U32X 3GYMI 3T62D 1DENA 1UUAA 1K6UA 3FP6I 2PTCI 1BUNB 1BZ5A 1CA0D 1YLCB 2FTMB 2ZVXA 3OFWA 3UIRC 3LDJA 1DTKA 1T8MB 2ZJXA 1ADZA 5PTIA 3D65I 1T7CB 1BRBI 3WNYA 1FAKI 1FY8I 1LD6A 3AUDA 2TPII 3BTDI 3BYBA 1KTHA 1AAPA 1JV8A 1PITA 3BTMI 3P92E 2IJOI 1G6XA 4PTIA 4NTWB 4BNRI 3BTTI 3BTEI 1CBWD 2LFKA 5JB7A 1BRCI 2R9PE 2RA3C 1ZJDB 2J6DA 1D0DB 2FTLI 1DTXA 9PTIA 5JB5A 3FP7J 3BTFI 4U30W 3BTQI 3U1JE 1UUBA 1D0DA 3TGKI 5C67C 3BTWI 2FI3I 2UUYB 1BIKA 4TPII 1SHPA 1KNTA 1YKTB 1OA55 3BTGI 1AALA 2DDJA 3AUCA 2TGPI 4Y10I 1T8OB 3L33E 3AUIA 2CA7A 2LFLA 3AUEA 1P2KI 2M99A 2UUXA 1DEMA 1F5RI 1TCPA 3OTJI 1MTND 4WWYC 4Y0ZI 1TPAI 1JV9A
chains in the Genus database with same CATH topology
1BHCA 1Y62A 2ODYE 3AUGA 4NTYB 2W8XA 1BZXI 1EJMB 1IRHA 3AUHA 1P2II 1QLQA 1YC0I 3LDIA 3TPII 1B0CA 3TGII 3M7QB 1BTHP 1T8NB 4ISOB 4WXVC 4BD9B 4DG4C 1EAWB 4Y11I 1P2NB 3L3TE 2M01A 3BTKI 1TOCR 1ZR0B 1P2OB 8PTIA 5JB6A 1KUNA 1TAPA 1CO7I 1TAWB 1BPIA 1LD5A 4Y0YI 3TGJI 3AUBA 3LDMA 2FI4I 2KAII 1BPTA 1BF0A 1P2JI 4DTGK 1P2MB 2KNTA 3CI7A 3UOUB 2DDIA 2FI5I 6PTIA 2JOTA 3BTHI 1BTIA 1OA65 3P95E 4ISLB 2KCRA 1F7ZI 4ISNB 1T8LB 1TFXC 1NAGA 1JC6A 2HEXA 4NTXB 4BQDA 5JB4A 1YLDB 1FANA 7PTIA 3FP8I 1KIGI 1P2QB 4U32X 3GYMI 3T62D 1DENA 1UUAA 1K6UA 3FP6I 2PTCI 1BUNB 1BZ5A 1CA0D 1YLCB 2FTMB 2ZVXA 3OFWA 3UIRC 3LDJA 1DTKA 1T8MB 2ZJXA 1ADZA 5PTIA 3D65I 1T7CB 1BRBI 3WNYA 1FAKI 1FY8I 1LD6A 3AUDA 2TPII 3BTDI 3BYBA 1KTHA 1AAPA 1JV8A 1PITA 3BTMI 3P92E 2IJOI 1G6XA 4PTIA 4NTWB 4BNRI 3BTTI 3BTEI 1CBWD 2LFKA 5JB7A 1BRCI 2R9PE 2RA3C 1ZJDB 2J6DA 1D0DB 2FTLI 1DTXA 9PTIA 5JB5A 3FP7J 3BTFI 4U30W 3BTQI 3U1JE 1UUBA 1D0DA 3TGKI 5C67C 3BTWI 2FI3I 2UUYB 1BIKA 4TPII 1SHPA 1KNTA 1YKTB 1OA55 3BTGI 1AALA 2DDJA 3AUCA 2TGPI 4Y10I 1T8OB 3L33E 3AUIA 2CA7A 2LFLA 3AUEA 1P2KI 2M99A 2UUXA 1DEMA 1F5RI 1TCPA 3OTJI 1MTND 4WWYC 4Y0ZI 1TPAI 1JV9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BHC A;  1Y62 A;  2ODY E;  3AUG A;  4NTY B;  2W8X A;  1BZX I;  1EJM B;  1IRH A;  3AUH A;  1P2I I;  1QLQ A;  1YC0 I;  3LDI A;  3TPI I;  1B0C A;  3TGI I;  3M7Q B;  1BTH P;  1T8N B;  4ISO B;  4WXV C;  4BD9 B;  4DG4 C;  1EAW B;  4Y11 I;  1P2N B;  3L3T E;  2M01 A;  3BTK I;  1TOC R;  1ZR0 B;  1P2O B;  8PTI A;  5JB6 A;  1KUN A;  1TAP A;  1CO7 I;  1TAW B;  1BPI A;  1LD5 A;  4Y0Y I;  3TGJ I;  3AUB A;  3LDM A;  2FI4 I;  2KAI I;  1BPT A;  1BF0 A;  1P2J I;  4DTG K;  1P2M B;  2KNT A;  3CI7 A;  3UOU B;  2DDI A;  2FI5 I;  6PTI A;  2JOT A;  3BTH I;  1BTI A;  1OA6 5;  3P95 E;  4ISL B;  2KCR A;  1F7Z I;  4ISN B;  1T8L B;  1TFX C;  1NAG A;  1JC6 A;  2HEX A;  4NTX B;  4BQD A;  5JB4 A;  1YLD B;  1FAN A;  7PTI A;  3FP8 I;  1KIG I;  1P2Q B;  4U32 X;  3GYM I;  3T62 D;  1DEN A;  1UUA A;  1K6U A;  3FP6 I;  2PTC I;  1BUN B;  1BZ5 A;  1CA0 D;  1YLC B;  2FTM B;  2ZVX A;  3OFW A;  3UIR C;  3LDJ A;  1DTK A;  1T8M B;  2ZJX A;  1ADZ A;  5PTI A;  3D65 I;  1T7C B;  1BRB I;  3WNY A;  1FAK I;  1FY8 I;  1LD6 A;  3AUD A;  2TPI I;  3BTD I;  3BYB A;  1KTH A;  1AAP A;  1JV8 A;  1PIT A;  3BTM I;  3P92 E;  2IJO I;  1G6X A;  4PTI A;  4NTW B;  4BNR I;  3BTT I;  3BTE I;  1CBW D;  2LFK A;  5JB7 A;  1BRC I;  2R9P E;  2RA3 C;  1ZJD B;  2J6D A;  1D0D B;  2FTL I;  1DTX A;  9PTI A;  5JB5 A;  3FP7 J;  3BTF I;  4U30 W;  3BTQ I;  3U1J E;  1UUB A;  1D0D A;  3TGK I;  5C67 C;  3BTW I;  2FI3 I;  2UUY B;  1BIK A;  4TPI I;  1SHP A;  1KNT A;  1YKT B;  1OA5 5;  3BTG I;  1AAL A;  2DDJ A;  3AUC A;  2TGP I;  4Y10 I;  1T8O B;  3L33 E;  3AUI A;  2CA7 A;  2LFL A;  3AUE A;  1P2K I;  2M99 A;  2UUX A;  1DEM A;  1F5R I;  1TCP A;  3OTJ I;  1MTN D;  4WWY C;  4Y0Z I;  1TPA I;  1JV9 A; 
#chains in the Genus database with same CATH topology
 1BHC A;  1Y62 A;  2ODY E;  3AUG A;  4NTY B;  2W8X A;  1BZX I;  1EJM B;  1IRH A;  3AUH A;  1P2I I;  1QLQ A;  1YC0 I;  3LDI A;  3TPI I;  1B0C A;  3TGI I;  3M7Q B;  1BTH P;  1T8N B;  4ISO B;  4WXV C;  4BD9 B;  4DG4 C;  1EAW B;  4Y11 I;  1P2N B;  3L3T E;  2M01 A;  3BTK I;  1TOC R;  1ZR0 B;  1P2O B;  8PTI A;  5JB6 A;  1KUN A;  1TAP A;  1CO7 I;  1TAW B;  1BPI A;  1LD5 A;  4Y0Y I;  3TGJ I;  3AUB A;  3LDM A;  2FI4 I;  2KAI I;  1BPT A;  1BF0 A;  1P2J I;  4DTG K;  1P2M B;  2KNT A;  3CI7 A;  3UOU B;  2DDI A;  2FI5 I;  6PTI A;  2JOT A;  3BTH I;  1BTI A;  1OA6 5;  3P95 E;  4ISL B;  2KCR A;  1F7Z I;  4ISN B;  1T8L B;  1TFX C;  1NAG A;  1JC6 A;  2HEX A;  4NTX B;  4BQD A;  5JB4 A;  1YLD B;  1FAN A;  7PTI A;  3FP8 I;  1KIG I;  1P2Q B;  4U32 X;  3GYM I;  3T62 D;  1DEN A;  1UUA A;  1K6U A;  3FP6 I;  2PTC I;  1BUN B;  1BZ5 A;  1CA0 D;  1YLC B;  2FTM B;  2ZVX A;  3OFW A;  3UIR C;  3LDJ A;  1DTK A;  1T8M B;  2ZJX A;  1ADZ A;  5PTI A;  3D65 I;  1T7C B;  1BRB I;  3WNY A;  1FAK I;  1FY8 I;  1LD6 A;  3AUD A;  2TPI I;  3BTD I;  3BYB A;  1KTH A;  1AAP A;  1JV8 A;  1PIT A;  3BTM I;  3P92 E;  2IJO I;  1G6X A;  4PTI A;  4NTW B;  4BNR I;  3BTT I;  3BTE I;  1CBW D;  2LFK A;  5JB7 A;  1BRC I;  2R9P E;  2RA3 C;  1ZJD B;  2J6D A;  1D0D B;  2FTL I;  1DTX A;  9PTI A;  5JB5 A;  3FP7 J;  3BTF I;  4U30 W;  3BTQ I;  3U1J E;  1UUB A;  1D0D A;  3TGK I;  5C67 C;  3BTW I;  2FI3 I;  2UUY B;  1BIK A;  4TPI I;  1SHP A;  1KNT A;  1YKT B;  1OA5 5;  3BTG I;  1AAL A;  2DDJ A;  3AUC A;  2TGP I;  4Y10 I;  1T8O B;  3L33 E;  3AUI A;  2CA7 A;  2LFL A;  3AUE A;  1P2K I;  2M99 A;  2UUX A;  1DEM A;  1F5R I;  1TCP A;  3OTJ I;  1MTN D;  4WWY C;  4Y0Z I;  1TPA I;  1JV9 A; 
#chains in the Genus database with same CATH homology
 1BHC A;  1Y62 A;  2ODY E;  3AUG A;  4NTY B;  2W8X A;  1BZX I;  1EJM B;  1IRH A;  3AUH A;  1P2I I;  1QLQ A;  1YC0 I;  3LDI A;  3TPI I;  1B0C A;  3TGI I;  3M7Q B;  1BTH P;  1T8N B;  4ISO B;  4WXV C;  4BD9 B;  4DG4 C;  1EAW B;  4Y11 I;  1P2N B;  3L3T E;  2M01 A;  3BTK I;  1TOC R;  1ZR0 B;  1P2O B;  8PTI A;  5JB6 A;  1KUN A;  1TAP A;  1CO7 I;  1TAW B;  1BPI A;  1LD5 A;  4Y0Y I;  3TGJ I;  3AUB A;  3LDM A;  2FI4 I;  2KAI I;  1BPT A;  1BF0 A;  1P2J I;  4DTG K;  1P2M B;  2KNT A;  3CI7 A;  3UOU B;  2DDI A;  2FI5 I;  6PTI A;  2JOT A;  3BTH I;  1BTI A;  1OA6 5;  3P95 E;  4ISL B;  2KCR A;  1F7Z I;  4ISN B;  1T8L B;  1TFX C;  1NAG A;  1JC6 A;  2HEX A;  4NTX B;  4BQD A;  5JB4 A;  1YLD B;  1FAN A;  7PTI A;  3FP8 I;  1KIG I;  1P2Q B;  4U32 X;  3GYM I;  3T62 D;  1DEN A;  1UUA A;  1K6U A;  3FP6 I;  2PTC I;  1BUN B;  1BZ5 A;  1CA0 D;  1YLC B;  2FTM B;  2ZVX A;  3OFW A;  3UIR C;  3LDJ A;  1DTK A;  1T8M B;  2ZJX A;  1ADZ A;  5PTI A;  3D65 I;  1T7C B;  1BRB I;  3WNY A;  1FAK I;  1FY8 I;  1LD6 A;  3AUD A;  2TPI I;  3BTD I;  3BYB A;  1KTH A;  1AAP A;  1JV8 A;  1PIT A;  3BTM I;  3P92 E;  2IJO I;  1G6X A;  4PTI A;  4NTW B;  4BNR I;  3BTT I;  3BTE I;  1CBW D;  2LFK A;  5JB7 A;  1BRC I;  2R9P E;  2RA3 C;  1ZJD B;  2J6D A;  1D0D B;  2FTL I;  1DTX A;  9PTI A;  5JB5 A;  3FP7 J;  3BTF I;  4U30 W;  3BTQ I;  3U1J E;  1UUB A;  1D0D A;  3TGK I;  5C67 C;  3BTW I;  2FI3 I;  2UUY B;  1BIK A;  4TPI I;  1SHP A;  1KNT A;  1YKT B;  1OA5 5;  3BTG I;  1AAL A;  2DDJ A;  3AUC A;  2TGP I;  4Y10 I;  1T8O B;  3L33 E;  3AUI A;  2CA7 A;  2LFL A;  3AUE A;  1P2K I;  2M99 A;  2UUX A;  1DEM A;  1F5R I;  1TCP A;  3OTJ I;  1MTN D;  4WWY C;  4Y0Z I;  1TPA I;  1JV9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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