2PNQA

Crystal structure of pyruvate dehydrogenase phosphatase 1 (pdp1)
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
459
structure length
382
Chain Sequence
LTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNRLPANAPIEDRRSATTCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVELLPILQWHKHPNDYFSKEASKLYFNGLRTYWQELIDLDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELQRLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQQNAATHLIRHAVGYRDDITIIVVQFNSHVVGAYQNQEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of pyruvate dehydrogenase phosphatase 1 and its functional implications.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords [Pyruvate dehydrogenase [lipoamide]]-phosphatase 1
total genus 124
structure length 382
sequence length 459
chains with identical sequence B
ec nomenclature ec 3.1.3.43: [Pyruvate dehydrogenase (acetyl-transferring)]-phosphatase.
pdb deposition date 2007-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00481 PP2C Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2pnqA00
4RAFA 2J4OA 4YZGA 3EQ2A 4LG5B 5JO1B 2POMA 3UJGB 3W44A 3JRQA 2JFSA 3KDJB 4OICB 3D8KA 3UJLB 3F79A 3W42A 4DS8B 4JNDA 4YZHA 1TXOA 3KE6A 5JO2B 3T9QA 4WVOB 3W40A 3FXOA 3QN1B 2IQ1A 5ITIA 3PU9A 3W43A 4RAGA 2P8EA 3KB3B 2CM1A 2V06A 2I0OA 3RT0A 4LA7B 4LGBB 3MQ3A 2JFRA 3RNRA 4N0GA 2XZVA 4DA1A 2J86A 2J82A 3FXKA 3ES2A 2I44A 3UJKA 2IRMA 3FXLA 2PNQA 5F1MA 3T91A 3FXJA 3NMVB 3FXMA 3W41A 2POPA 4LGAB 3W45A 2JFTA 3ZVUB 2Y09A 3NMTB 4RA2A 3N3CA 2ISNA 2PK0A 5D2UA 1A6QA 3ZT9A 3NMNB
chains in the Genus database with same CATH superfamily
4RAFA 2J4OA 4YZGA 3EQ2A 4LG5B 5JO1B 2POMA 3UJGB 3W44A 3JRQA 2JFSA 3KDJB 4IIPA 4OICB 3D8KA 3UJLB 3F79A 3W42A 4DS8B 4JNDA 4YZHA 1TXOA 3KE6A 5JO2B 3T9QA 4WVOB 3W40A 3FXOA 3QN1B 2IQ1A 5ITIA 3PU9A 3W43A 4RAGA 4IIKA 2P8EA 3KB3B 2CM1A 2V06A 2I0OA 3RT0A 4LA7B 4LGBB 3MQ3A 2JFRA 3RNRA 4N0GA 2XZVA 4DA1A 2J86A 2J82A 3FXKA 3ES2A 2I44A 3UJKA 2IRMA 3FXLA 2PNQA 5F1MA 3T91A 3FXJA 3NMVB 3FXMA 3W41A 2POPA 4LGAB 3W45A 2JFTA 3ZVUB 2Y09A 3NMTB 4RA2A 3N3CA 2ISNA 2PK0A 5D2UA 1A6QA 3ZT9A 3NMNB
chains in the Genus database with same CATH topology
4RAFA 2J4OA 4YZGA 3EQ2A 4LG5B 5JO1B 2POMA 3UJGB 3W44A 3JRQA 2JFSA 3KDJB 4OICB 3D8KA 3UJLB 3F79A 3W42A 4DS8B 4JNDA 4YZHA 1TXOA 3KE6A 5JO2B 3T9QA 4WVOB 3W40A 3FXOA 3QN1B 2IQ1A 5ITIA 3PU9A 3W43A 4RAGA 2P8EA 3KB3B 2CM1A 2V06A 2I0OA 3RT0A 4LA7B 4LGBB 3MQ3A 2JFRA 3RNRA 4N0GA 2XZVA 4DA1A 2J86A 2J82A 3FXKA 3ES2A 2I44A 3UJKA 2IRMA 3FXLA 2PNQA 5F1MA 3T91A 3FXJA 3NMVB 3FXMA 3W41A 2POPA 4LGAB 3W45A 2JFTA 3ZVUB 2Y09A 3NMTB 4RA2A 3N3CA 2ISNA 2PK0A 5D2UA 1A6QA 3ZT9A 3NMNB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RAF A;  2J4O A;  4YZG A;  3EQ2 A;  4LG5 B;  5JO1 B;  2POM A;  3UJG B;  3W44 A;  3JRQ A;  2JFS A;  3KDJ B;  4OIC B;  3D8K A;  3UJL B;  3F79 A;  3W42 A;  4DS8 B;  4JND A;  4YZH A;  1TXO A;  3KE6 A;  5JO2 B;  3T9Q A;  4WVO B;  3W40 A;  3FXO A;  3QN1 B;  2IQ1 A;  5ITI A;  3PU9 A;  3W43 A;  4RAG A;  2P8E A;  3KB3 B;  2CM1 A;  2V06 A;  2I0O A;  3RT0 A;  4LA7 B;  4LGB B;  3MQ3 A;  2JFR A;  3RNR A;  4N0G A;  2XZV A;  4DA1 A;  2J86 A;  2J82 A;  3FXK A;  3ES2 A;  2I44 A;  3UJK A;  2IRM A;  3FXL A;  2PNQ A;  5F1M A;  3T91 A;  3FXJ A;  3NMV B;  3FXM A;  3W41 A;  2POP A;  4LGA B;  3W45 A;  2JFT A;  3ZVU B;  2Y09 A;  3NMT B;  4RA2 A;  3N3C A;  2ISN A;  2PK0 A;  5D2U A;  1A6Q A;  3ZT9 A;  3NMN B; 
#chains in the Genus database with same CATH topology
 4RAF A;  2J4O A;  4YZG A;  3EQ2 A;  4LG5 B;  5JO1 B;  2POM A;  3UJG B;  3W44 A;  3JRQ A;  2JFS A;  3KDJ B;  4IIP A;  4OIC B;  3D8K A;  3UJL B;  3F79 A;  3W42 A;  4DS8 B;  4JND A;  4YZH A;  1TXO A;  3KE6 A;  5JO2 B;  3T9Q A;  4WVO B;  3W40 A;  3FXO A;  3QN1 B;  2IQ1 A;  5ITI A;  3PU9 A;  3W43 A;  4RAG A;  4IIK A;  2P8E A;  3KB3 B;  2CM1 A;  2V06 A;  2I0O A;  3RT0 A;  4LA7 B;  4LGB B;  3MQ3 A;  2JFR A;  3RNR A;  4N0G A;  2XZV A;  4DA1 A;  2J86 A;  2J82 A;  3FXK A;  3ES2 A;  2I44 A;  3UJK A;  2IRM A;  3FXL A;  2PNQ A;  5F1M A;  3T91 A;  3FXJ A;  3NMV B;  3FXM A;  3W41 A;  2POP A;  4LGA B;  3W45 A;  2JFT A;  3ZVU B;  2Y09 A;  3NMT B;  4RA2 A;  3N3C A;  2ISN A;  2PK0 A;  5D2U A;  1A6Q A;  3ZT9 A;  3NMN B; 
#chains in the Genus database with same CATH homology
 4RAF A;  2J4O A;  4YZG A;  3EQ2 A;  4LG5 B;  5JO1 B;  2POM A;  3UJG B;  3W44 A;  3JRQ A;  2JFS A;  3KDJ B;  4OIC B;  3D8K A;  3UJL B;  3F79 A;  3W42 A;  4DS8 B;  4JND A;  4YZH A;  1TXO A;  3KE6 A;  5JO2 B;  3T9Q A;  4WVO B;  3W40 A;  3FXO A;  3QN1 B;  2IQ1 A;  5ITI A;  3PU9 A;  3W43 A;  4RAG A;  2P8E A;  3KB3 B;  2CM1 A;  2V06 A;  2I0O A;  3RT0 A;  4LA7 B;  4LGB B;  3MQ3 A;  2JFR A;  3RNR A;  4N0G A;  2XZV A;  4DA1 A;  2J86 A;  2J82 A;  3FXK A;  3ES2 A;  2I44 A;  3UJK A;  2IRM A;  3FXL A;  2PNQ A;  5F1M A;  3T91 A;  3FXJ A;  3NMV B;  3FXM A;  3W41 A;  2POP A;  4LGA B;  3W45 A;  2JFT A;  3ZVU B;  2Y09 A;  3NMT B;  4RA2 A;  3N3C A;  2ISN A;  2PK0 A;  5D2U A;  1A6Q A;  3ZT9 A;  3NMN B; 
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